scholarly journals Severity of Migraine with or without comorbidities: A Comparative Study

2017 ◽  
Vol 1 (2) ◽  
pp. 33-36 ◽  
Author(s):  
Mohammad Akter Hossain ◽  
Quazi Deen Mohammad ◽  
Mansur Habib ◽  
Md. Azharul Hoque ◽  
Md. Badrul Alam ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Cross Sectional Study ◽  
Major Depressive ◽  
Cross Sectional ◽  
Medical College ◽  
Group I ◽  
Group Ii ◽  
Headache Clinic ◽  
Severe Migraine

Background: Migraine causes difficulties in daily life. Objective: The purpose of this present study was to assess the severity of migraine associated with comorbidities.Methodology: This cross sectional study was carried out in Headache Clinic and Neurology outdoor in the Department of Neurology at Dhaka Medical College and Hospital (DMCH), Dhaka during the period of July 2010 to June 2011 for a period of one (01) year. All the patients presented with migraine were included as study population who were divided into two groups. Migraine patients without comorbidities were designated as group I and with comorbidities were in group II. The comorbidities were assessed which were both physical as well as psychiatric. The severity of migraine was assessed on the basis of four principal components like pain intensity, nausea, disability and tolerability.Result: A total of 70 patients with migraine were recruited of which 37 patients were in group I and 33 patients were in group II. In group II major depressive disorder was in 8(24.3%) cases, generalized anxiety disorder was in 6(18.1%) cases and hypertensive was in 7(21.2%) cases. Among 8 major depressive disorder patients, mild, moderate and severe migraines were found in 1(3.03%) cases, 2(6.06%) cases and 5(15.15%) cases respectively. Out of 6 GAD patients, mild, moderate and severe migraine were found in 1(3.03%) case, 1(3.03%) case and 4(12.12%) cases. Seven patients were hypertensive of which 1(3.03) patient had mild, 2(6.06%) had moderate and 4(12.12%) had severe migraine. Mild migraine was found in 18(48.6%) patients in group I and 6(18.2%) patients in group II. Moderate migraine was found in 12(32.5%) patients and 8(24.2%) in group I and group II respectively. Severe migraine was found in 7(18.9%) patients in group I and 19(57.6%) patients in group II.Conclusion: Severity of migraine is associated with different physical and psychiatric comorbidities. Journal of National Institute of Neurosciences Bangladesh, 2015;1(2): 33-36

scholarly journals TO STUDY THE ONSET AND PROGRESSION OF AIRWAY ABNORMALITY IN TERMS OF ALTERATION IN PFT IN ASYMPTOMATIC SMOKERS.

2019 ◽  
Vol 3 (11) ◽  
Author(s):  
Dr. Hitesh Kumar Solanki ◽  
Dr. Omnath P Yadav ◽  
Dr. Anita J Gojiya
Keyword(s):  
Lung Function ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Medical College ◽  
Group I ◽  
Significant Difference ◽  
History Of ◽  
Young Smokers ◽  
The Mean ◽  
Group Ii

The study was conducted in department of physiology, B J Medical College, Ahmedabad from Mar. 2012 to Feb. 2013. This was a cross-sectional study to evaluate the effect of smoking on lung   function and serum lipids in asymptomatic smokers   and comparable non   smokers. The mean of the various spirometric parameters were calculated of the subjects for both the groups. The mean FVC in group I and group II was 2.60 ± 0.62 L and 4.10 ± 0.64L respectively. The mean FEV1 in group I was 1.91 ± 0.57L and     3.19 ± 0.77L in group II Group I had mean FEF25% - 75% and PEFR of 1.98 ± 0.67L/sec and 4.50 ± 1.57L/sec respectively. Group II had mean FEF25 – 75% of 4.22 ± 1.23L/sec and a mean PEFR of 7.22 ± 1.42L/sec. In young smokers and asymptomatic, still the spirometric values were significantly deranged as compared to controls. Even smokers with history of less pack years of smoking also had significant abnormalities of lung function. All he spirometric values in the two groups had statistically highly significant difference and were higher in non-smokers as compared to smokers. The spirometric values were reduced in smokers with history of smoking for as low as two pack years. Keywords: Progression, PFT, Asymptomatic & Smokers

scholarly journals Major depression subtypes are differentially associated with migraine subtype, prevalence and severity

Cephalalgia ◽  
2019 ◽  
Vol 40 (4) ◽  
pp. 347-356 ◽  
Author(s):  
Claudia Pisanu ◽  
Emma Lundin ◽  
Martin Preisig ◽  
Mehdi Gholam-Rezaee ◽  
Enrique Castelao ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Migraine With Aura ◽  
Migraine Without Aura ◽  
Population Based ◽  
Cross Sectional Study ◽  
High Rate ◽  
Major Depressive ◽  
Cross Sectional ◽  
Depression Subtypes

Objective Migraine and major depressive disorder show a high rate of comorbidity, but little is known about the associations between the subtypes of major depressive disorder and migraine. In this cross-sectional study we aimed at investigating a) the lifetime associations between the atypical, melancholic, combined and unspecified subtype of major depressive disorder and migraine with and without aura and b) the associations between major depressive disorder and its subtypes and the severity of migraine. Methods A total of 446 subjects with migraine (migraine without aura: n = 294; migraine with aura: n = 152) and 2511 controls from the population-based CoLaus/PsyCoLaus study, Switzerland, were included. Associations between major depressive disorder subtypes and migraine characteristics were tested using binary logistic or linear regression. Results Melancholic, combined and unspecified major depressive disorder were associated with increased frequency of migraine with aura, whereas only melancholic major depressive disorder was associated with increased frequency of migraine without aura. Lifetime and unspecified major depressive disorder were associated with severe migraine intensity among subjects with migraine with aura but not migraine without aura, while combined major depressive disorder was associated with higher migraine frequency independently from migraine subtype. Conclusion This study suggests that melancholic but not atypical major depressive disorder is associated with migraine and migraine subtypes. Future studies exploring pathophysiological mechanisms shared between melancholic depression and migraine are warranted.

Investigation of associations between recurrence of major depressive disorder and spinal posture alignment: A quantitative cross-sectional study

2017 ◽  
Vol 52 ◽  
pp. 258-264 ◽  
Author(s):  
Janette Z. Canales ◽  
Juliana T. Fiquer ◽  
Rodolfo N. Campos ◽  
Márcio Gerhardt Soeiro-de-Souza ◽  
Ricardo Alberto Moreno
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Major Depressive ◽  
Cross Sectional ◽  
Spinal Posture

White matter fiber microstructure is associated with prior hospitalizations rather than acute symptomatology in major depressive disorder

2020 ◽  
pp. 1-9
Author(s):  
Susanne Meinert ◽  
Elisabeth J. Leehr ◽  
Dominik Grotegerd ◽  
Jonathan Repple ◽  
Katharina Förster ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Diffusion Tensor ◽  
Mean Diffusivity ◽  
Cross Sectional Study ◽  
Disease State ◽  
Major Depressive ◽  
Cross Sectional ◽  
Course Of Illness ◽  
The Right

Abstract Background Eighty percent of all patients suffering from major depressive disorder (MDD) relapse at least once in their lifetime. Thus, understanding the neurobiological underpinnings of the course of MDD is of utmost importance. A detrimental course of illness in MDD was most consistently associated with superior longitudinal fasciculus (SLF) fiber integrity. As similar associations were, however, found between SLF fiber integrity and acute symptomatology, this study attempts to disentangle associations attributed to current depression from long-term course of illness. Methods A total of 531 patients suffering from acute (N = 250) or remitted (N = 281) MDD from the FOR2107-cohort were analyzed in this cross-sectional study using tract-based spatial statistics for diffusion tensor imaging. First, the effects of disease state (acute v. remitted), current symptom severity (BDI-score) and course of illness (number of hospitalizations) on fractional anisotropy (FA), mean diffusivity (MD), radial diffusivity (RD), and axial diffusivity were analyzed separately. Second, disease state and BDI-scores were analyzed in conjunction with the number of hospitalizations to disentangle their effects. Results Disease state (pFWE < 0.042) and number of hospitalizations (pFWE< 0.032) were associated with decreased FA and increased MD and RD in the bilateral SLF. A trend was found for the BDI-score (pFWE > 0.067). When analyzed simultaneously only the effect of course of illness remained significant (pFWE < 0.040) mapping to the right SLF. Conclusions Decreased FA and increased MD and RD values in the SLF are associated with more hospitalizations when controlling for current psychopathology. SLF fiber integrity could reflect cumulative illness burden at a neurobiological level and should be targeted in future longitudinal analyses.

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