scholarly journals Endoscopic Evaluation of Dyspeptic Patients

2021 ◽  
Vol 12 (1) ◽  
pp. 9-14
Author(s):  
Md Ruhul Amin Sarker ◽  
Md Atiqul Islam ◽  
Mohammad Habibullah ◽  
Saleh Mohammad Ali ◽  
Abu Hena Md Shohel Rana ◽  
...  
Keyword(s):  
Large Scale ◽  
Epigastric Pain ◽  
Age Groups ◽  
Duodenal Mucosa ◽  
College Hospital ◽  
Cross Sectional ◽  
Socioeconomic Condition ◽  
Upper Gi ◽  
Gastrointestinal Problems ◽  
Non Ulcer Dyspepsia

Background: Dyspepsia is a common gastrointestinal problems affecting all age groups & social classes. Objectives: The purpose of the study was to determine the endoscopic findings of dyspeptic patients & to observe the demographic characteristics (age, sex, residence, education, socioeconomic condition) of the patients presented with dyspepsia. Methodology: This was a cross-sectional study conducted at Department of Medicine, Rangpur Medical College Hospital, Rangpur over a period of 1 year from 1st June 2010 to 31st May 2011. 150 dyspeptic patients of 18 or > 18 years old irrespective of sexes and suffering from one or more of the five symptoms (flatulence, food intolerance, epigastric pain, heartburn and aerophagia) for at least 6 months duration were recruited for the study from outpatient and inpatient department who were met the inclusion & exclusion criteria. Data were collected by using a structured questionnaire after taking written consent & upper GI Endocopy were done following meticulous history & through physical examination. Result: Over one-third (36%) of the patients were below 30 years, 17% between 30 – 40 years old, predominantly were rural residents, having primary to secondary level of education with monthly income below Taka 10000. Males to females ratio were 2:1. More than half (50.6%) of the patients was smoker, 32.7% had habit of taking tea, 10% were tobacco chewing and rest 6.7% used to take spicy meal.. Epigastric discomfort, flatulence and heartburn were the common complaints in both male and females but vomiting were proportionately higher in male dyspeptics compared to the female dyspeptics. Common associated symptoms like constipation and weight loss were equally in both sexes. Upper GI endoscopy revealed 17.3% of male and 11.5% of female with abnormal findings.Others abnormal findings included gastric ulcer, gastritis and duodenal ulcers (17.6 vs. 33.3%; 23.6 vs. 50% and 17.6 vs. 16.7% in male and female respectively). Majority (nearly 90% in either sex) of patients does not show any lesions on endoscopic examination and hence can be considered as non-ulcer dyspepsia. Conclusion: The study concludes that majority of patients with complaints of dyspepsia have no lesion on the gastric or duodenal mucosa and can be considered non-ulcer dyspepsia. The study findings also suggest that dyspepsia is a disease of young and early middle aged people with males being more likely to develop the disease than the females. However, large-scale community survey is recommended for further evaluation of dyspepsia. J Shaheed Suhrawardy Med Coll, December 2020, Vol.12(1); 9-14

scholarly journals Drug Prescription Profiles in Patients with Polypharmacy in Spain: A Large-Scale Pharmacoepidemiologic Study Using Real-World Data

2021 ◽  
Vol 18 (9) ◽  
pp. 4754
Author(s):  
Miguel Ángel Hernández-Rodríguez ◽  
Ermengol Sempere-Verdú ◽  
Caterina Vicens-Caldentey ◽  
Francisca González-Rubio ◽  
Félix Miguel-García ◽  
...  
Keyword(s):  
Psychotropic Drugs ◽  
Large Scale ◽  
Anatomical Therapeutic Chemical ◽  
Drug Prescription ◽  
Age Groups ◽  
System Level ◽  
Real World Data ◽  
Converting Enzyme Inhibitors ◽  
Cross Sectional ◽  
Β Blockers

We aimed to identify and compare medication profiles in populations with polypharmacy between 2005 and 2015. We conducted a cross-sectional study using information from the Computerized Database for Pharmacoepidemiologic Studies in Primary Care (BIFAP, Spain). We estimated the prevalence of therapeutic subgroups in all individuals 15 years of age and older with polypharmacy (≥5 drugs during ≥6 months) using the Anatomical Therapeutic Chemical classification system level 4, by sex and age group, for both calendar years. The most prescribed drugs were proton-pump inhibitors (PPIs), statins, antiplatelet agents, benzodiazepine derivatives, and angiotensin-converting enzyme inhibitors. The greatest increases between 2005 and 2015 were observed in PPIs, statins, other antidepressants, and β-blockers, while the prevalence of antiepileptics was almost tripled. We observed increases in psychotropic drugs in women and cardiovascular medications in men. By patient´s age groups, there were notable increases in antipsychotics, antidepressants, and antiepileptics (15–44 years); antidepressants, PPIs, and selective β-blockers (45–64 years); selective β-blockers, biguanides, PPIs, and statins (65–79 years); and in statins, selective β-blockers, and PPIs (80 years and older). Our results revealed important increases in the use of specific therapeutic subgroups, like PPIs, statins, and psychotropic drugs, highlighting opportunities to design and implement strategies to analyze such prescriptions’ appropriateness.

scholarly journals Relationship between Stature and Length of Tendo Achilles in Adult Male and Female of Bangladesh

2020 ◽  
Vol 7 (2) ◽  
pp. 80-83
Author(s):  
Sanjida Amin ◽  
Shamim Ara ◽  
Rawshon Naznin ◽  
Umma Marium ◽  
Farah Diba ◽  
...  
Keyword(s):  
Medical Science ◽  
Age Groups ◽  
Medical College Hospital ◽  
Radiology Department ◽  
College Hospital ◽  
Cross Sectional ◽  
Male And Female ◽  
Medical College ◽  
Tendon Thickness ◽  
Ankle Flexibility

Background: Tendo Achilles injuries are usually related to poor ankle flexibility and strength and to overuse. Morphology of tendo Achilles is an important tool for its assessment which can be done by measuring tendon thickness, cross-sectional area and length of tendon. Objective: The aim of the study was to correlate length of tendo Achilles with stature in several age groups of sedentary people as measured by ultrasonography. Materials and method: This cross sectional analytical type of study was conducted in the department of Anatomy, Dhaka Medical College Hospital, Dhaka, Bangladesh from July 2013 to June 2014. The present study was performed on 200 tendo Achilles of 100 people (50 male and 50 female) randomly selected from the patients who came to the Radiology department of Dhaka Medical College Hospital for ultrasonography of any region of their body other than leg. Results: In this study length of tendo Achilles was measured in both legs of adult people and was correlated with stature. Highly significant correlation was found between length of tendo Achilles with stature (p<0.001). Conclusion: The data of length of tendo Achilles obtained from the present study may provide valuable information in different aspects of medical science as a guide line for physiotherapists, radiologists, sports professionals and ortho-surgeons in early detection and monitoring of rehabilitation especially of professional athletes. Delta Med Col J. Jul 2019 7(2): 80-83

scholarly journals Leisure-Time Physical Activity Participation Trends 2014–2018: A Cross-Sectional Study in Poland

2019 ◽  
Vol 17 (1) ◽  
pp. 208 ◽  
Author(s):  
Elżbieta Biernat ◽  
Monika Piątkowska
Keyword(s):  
Physical Activity ◽  
Large Scale ◽  
Leisure Time ◽  
Leisure Time Physical Activity ◽  
Occupational Status ◽  
Age Groups ◽  
The Elderly ◽  
Sociodemographic Factors ◽  
World Health ◽  
Cross Sectional

Objective, the aim is an analysis of sociodemographic factors that had an essential relation with undertaking leisure-time physical activity—LTPA (with particular emphasis on World Health Organization (WHO) health recommendations) by adult Poles from a time-trend perspective. Methods, the paper is based on data retrieved from five large-scale surveys carried out on the representative samples of Poles aged 15–69 in 2014–2018 (n = 7347). In each wave, the Polish long version of the International Physical Activity Questionnaire was used. Results, the participation of Poles in LTPA constantly increases (p < 0.001) and the percentage of people meeting the dose of PA required for health recommendations is growing (on average, met by 43.9% of Polish men and 43.5% of women), which indicates a trend of behaviour of citizens of this country. The probability of realisation of WHO norms was determined by sex, age, place of residence and occupational status. Conclusion: it seems reasonable to develop Polish recommendations and guidelines for specific groups, including females and males, those who live in the villages and in the towns, different age groups: children/adolescents, adults (aged 50 to 59—most vulnerable to physical inactivity), the elderly, and various professional groups (especially farmers and physical workers).

scholarly journals A Study of Late Postpartum Eclampsia - 178 Cases

1970 ◽  
Vol 37 (2) ◽  
pp. 52-55
Author(s):  
Sahin Akhter Jahan Habib ◽  
Sayeeda Sultana
Keyword(s):  
Health Care Providers ◽  
Postpartum Period ◽  
Late Onset ◽  
Epigastric Pain ◽  
Prodromal Symptom ◽  
Care Providers ◽  
College Hospital ◽  
Cross Sectional ◽  
Medical College ◽  
Relationship Of

Objective: The purpose of this study was to determine whether there is a shift in the timing of eclampsia in relation to delivery and whether traditional symptoms precede impending postpartum eclampsia. Study Design: A cross - sectional hospital - based study conducted at Gynae Unit, Dhaka Medical College Hospital from January 2006 - December 2007. Data was collected regarding the relationship of the patient's first seizure to delivery prodromal symptoms, neuroimaging studies, use of magnesium sulfate, antihypertensive therapy and follow up medical care. The analysis focused on women who had late postpartum eclampsia. Result: During the study period 178 patients were diagnosed with eclampsia. Fifty eight women (33%) had postpartum eclampsia, of which 46 women (79%) had late onset (> 48 hrs.). Interestingly only 10 of these 46 women (22%) had been previously diagnosed with preeclampsia. Forty two pt.(91%) with late postpartum eclampsia had at least 1 prodromal symptom, and 24 pt. (52%) had> 1 symptom that heralded the seizure : 40 women (87%) had headache , 20 women (44%) had visual changes, 10 (22%) had nausea or vomiting and 4 (9% ) experienced epigastric pain. Only 14 of this 42 women (33%) sought care for their symptoms , of whom 12 women (86%)had clinical evidence of preeclampsia that was not considered by the treating physician. Among all patients with eclampsia there were 14 cases of aspiration pneumonia,6 cases of pulmonary edema, 6 cases of pleural effusion 4 cases of DIC and no cases of maternal death. Conclusion: Current obstetric treatment has a resulted in a shift of eclampsia toward the postpartum period with most cases being seen as late postpartum. To reduce the rate of the postpartum eclampsia, efforts should be directed to the education of the health care providers and patients regarding the importance of prompt reporting and evaluation of symptoms of preeclampsia during the postpartum period.   DOI: 10.3329/bmj.v37i2.3594 Bangladesh Medical Journal 37(2) 2008 52-55

scholarly journals Bacteriological Profile of ESBL Producing Bacteria With Their Antibiotic Resistance Pattern

KYAMC Journal ◽  
2019 ◽  
Vol 10 (1) ◽  
pp. 7-12
Author(s):  
Mst Monira Khatun ◽  
Md Mofazzal Sharif ◽  
AKM Enamul Haque ◽  
Saiful Arifin ◽  
Khondoker Mohammad Ali
Keyword(s):  
Antibiotic Resistance ◽  
Family Income ◽  
Clinical Laboratory ◽  
Age Groups ◽  
Educational Status ◽  
Resistance Pattern ◽  
College Hospital ◽  
Cross Sectional ◽  
Extended Spectrum Beta Lactamase ◽  
Antibiotic Resistance Pattern

Background: Extended Spectrum Beta-Lactamase (ESBL) can cause infections, such as kidney infections, wound infections or in severe cases, blood infection. If a patient is prone to infection and the infection is caused by ESBLs, it can be more difficult to treat, because many of the commonly used antibiotics will not work against ESBLs. Materials and Method: This descriptive cross-sectional study was carried out to evaluate samples submitted for culture and sensitivity at Clinical Laboratory of North Bengal Medical College Hospital, Sirajganj the general objective identify the causative organisms and their antimicrobial resistance pattern. Results: Majority of subjects (37.5%) were from 46-60 years age group. ESBL resistance was significantly related with age groups and educational status. Resistance was not related with gender distribution, occupation, family size and yearly family income. Detection rate of ESBL production among Pseudomonas spp were (91.67 %), followed by Klebsiella spp. (83.33 %), Proteus spp. (69.49%), Esch. Coli (64.42 %) and others (82.35 %). Aztreonam, Ampicillin, Amoxyclave and Piperacillin were more resistant antibiotics against ESBL producing organisms. Conclusion: ESBL antibiotic resistance pattern should be determined in chronic Gram negative infection for effective treatment. KYAMC Journal Vol. 10, No.-1, April 2019, Page 7-12

scholarly journals Non-motor correlates of wrist-worn wearable sensor use in Parkinson’s disease: an exploratory analysis

2019 ◽  
Vol 5 (1) ◽  
Author(s):  
Daniel J. van Wamelen ◽  
Shweta Hota ◽  
Aleksandra Podlewska ◽  
Valentina Leta ◽  
Dhaval Trivedi ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Gastrointestinal Tract ◽  
Large Scale ◽  
Disease Duration ◽  
Wearable Sensors ◽  
International Study ◽  
Exploratory Analysis ◽  
College Hospital ◽  
Gastrointestinal Problems

Abstract Wearable sensors are becoming increasingly more available in Parkinson’s disease and are used to measure motor function. Whether non-motor symptoms (NMS) can also be measured with these wearable sensors remains unclear. We therefore performed a retrospective, exploratory, analysis of 108 patients with a diagnosis of idiopathic Parkinson’s disease enroled in the Non-motor Longitudinal International Study (UKCRN No. 10084) at King’s College Hospital, London, to determine the association between the range and nature of NMS and an accelerometer-based outcome measure of bradykinesia (BKS) and dyskinesia (DKS). NMS were assessed by the validated NMS Scale, and included, e.g., cognition, mood and sleep, and gastrointestinal, urinary and sexual problems. Multiple linear regression modelling was used to identify NMS associated with BKS and DKS. We found that BKS was associated with domains 6 (gastrointestinal tract; p = 0.006) and 8 (sexual function; p = 0.003) of the NMS scale. DKS was associated with domains 3 (mood/cognition; p = 0.016), 4 (perceptual problems; p = 0.025), 6 (gastrointestinal tract; p = 0.029) and 9 (miscellaneous, p = 0.003). In the separate domains, constipation was significantly associated with BKS. Delusions, dysphagia, hyposmia, weight change and hyperhidrosis were identified as significantly associated with DKS. None of the NMSS domains were associated with disease duration (p ≥ 0.08). In conclusion, measures of BKS and DKS were mainly associated with gastrointestinal problems, independent of disease duration, showing the potential for wearable devices to pick up on these symptoms. These exploratory results deserve further exploration, and more research on this topic in the form of comprehensive large-scale studies is needed.

scholarly journals Maternal Outcome in Ruptured Uterus: A Review of 72 Cases

2016 ◽  
Vol 5 (1) ◽  
pp. 20-26
Author(s):  
Nibedita Roy ◽  
Kamrun Nahar ◽  
Uttam Kumar Sarker ◽  
Fouzia Akter ◽  
Ayesha Beg ◽  
...  
Keyword(s):  
Age Groups ◽  
Cross Sectional Study ◽  
Study Data ◽  
Maternal Outcome ◽  
College Hospital ◽  
Cross Sectional ◽  
Medical College ◽  
Data Collection Sheet ◽  
Death Cases ◽  
Ruptured Uterus

This descriptive type of cross-sectional study of 72 cases of uterine rupture was conducted over 1 year (from September 2006 to August 2007) in the department of Obstetrics and Gynaecology, Mymensingh Medical College Hospital, Bangladesh to evaluate the maternal outcome of different types of surgery, to assess the maternal mortality and maternal morbidity. All cases of ruptured uterus which were received & treated and did not die within 30 minutes of admission are included in the study. Data were collected by preformed data collection sheet. The results showed that the common age groups were between 20-30 years in 31(68.00%) cases. Among all ruptured cases, 6 cases (8.33%) were Primigravida, 52 cases (72.22%) were between gravida 2nd to 4th and 14 cases (19.44%) were gravida 5th or above. Among all cases, 66 cases (91.66%) required blood transfusion; Subtotal hysterectomy was done in 36 cases (50.00%), total hysterectomy in 4 cases (5.56%), and repair of the rent in 32 cases (44.44%). Associated operations were done along with repair or hysterectomy in 13 (18.05%) cases. Postoperative complications were found in 23 (31.94%) cases. The shortest stay was 8 days & the longest stay was 62 days. The hospital staying was about 2 weeks in 48(66.70%) cases. Among 10 death cases (13.90%) maximum patient died within first 5 hours. The causes of maternal death were due to septicemia, renal failure and shock in 20%, 30% and 50% respectfully. CBMJ 2016 January: Vol. 05 No. 01 P: 20-26

scholarly journals Occurrence of Four Dengue Virus Serotypes and Chikungunya Virus in Kilombero, Tanzania during Dengue Outbreak in 2018

2020 ◽  
Author(s):  
Beatrice Chipwaza ◽  
Robert David Sumaye ◽  
Maja Weisser ◽  
Winfrid Gingo ◽  
Nicholas Kim-Wah Yeo ◽  
...  
Keyword(s):  
Large Scale ◽  
Age Groups ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Denv Serotypes ◽  
First Occurrence ◽  
Dry Seasons ◽  
Dengue Virus Serotypes ◽  
And Gender ◽  
Dry And Rainy Seasons

AbstractBackgroundDengue and Chikungunya viruses can cause large-scale epidemics with attack rates exceeding 80%. In Tanzania, there have been repeated outbreaks of dengue fever, the most recent one in 2018 and 2019 mostly reported in coastal areas. Despite its importance, there is limited knowledge on epidemiology of dengue (DENV) and chikungunya (CHIKV) in Tanzania. This study was conducted to investigate the prevalence of DENV and CHIKV in Kilombero district, South-Eastern Tanzania.MethodsA cross-sectional study was conducted at Kibaoni Health Center, in Kilombero district, in the rainy and dry seasons of 2018. Febrile patients of any age and gender were enrolled. Blood samples were taken and screened for DENV and CHIKV viral RNA by real-time RT-PCR assays.ResultsA total of 294 patients were recruited. Most were females (65%), and aged between 14⍰25 years (33%). DENV and CHIKV were detected in 29 (9.9%) and 3 (1.0%) patients, respectively. DENV was detected across all age groups and during both dry and rainy seasons. Although all four DENV serotypes were detected, serotypes 1 and 3 dominated and were present in 14 patients (42.4%) each. Additionally, the study showed DENV-1 and DENV-3 co-infections.ConclusionThis study reveals the co-circulation of all four DENV serotypes and CHIKV in Kilombero district. Importantly, we report the first occurrence of DENV-4 in Tanzania. Unlike previous DENV outbreaks caused by DENV-2, the 2018 outbreak was dominated by DENV-1 and DENV-3. Occurrence of all serotypes suggests the possibility of having severe clinical outcomes in future DENV epidemics in Tanzania.

scholarly journals Routine Multiple Duodenal Biopsy during Endoscopy of Dyspeptic Patients Seems Unnecessary for Screening of Celiac Disease

2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Amir Behforouz ◽  
Abbas Esmaeelzadeh ◽  
Homan Mosanan Mozaffari ◽  
Ali Mokhtarifar ◽  
Elham Faravani ◽  
...  
Keyword(s):  
Celiac Disease ◽  
Epigastric Pain ◽  
Diagnostic Yield ◽  
Positive Family History ◽  
Normal Mucosa ◽  
Duodenal Mucosa ◽  
Deficiency Anemia ◽  
Intestinal Biopsy ◽  
Cross Sectional ◽  
Postprandial Fullness

Introduction. Celiac disease (CD) is a chronic and common cause of dyspepsia with a rising prevalence worldwide. This study is aimed at investigating the prevalence of CD in dyspeptic patients based on serology and biopsy, determining the associated factors, and assessing the necessity of regular duodenal biopsies from normal mucosa in diagnosis of CD among dyspeptic patients. Methods. This cross-sectional study was performed on 530 adult dyspeptic patients who underwent gastroduodenoscopy in Imam Reza hospital, Mashhad, during 2016-2018. Demographic characteristics, clinical data, and laboratory analyses were extracted from hospital records. CD was diagnosed based on intestinal biopsy and serum antitissue transglutaminase (anti-TTG) levels. Mucosal lesions were classified according to the modified Marsh classification. Data were analyzed in SPSS with P < 0.05 being considered significant. Results. Overall, 163 males (30.8%) and 367 females (69.2%) with an average age of 46.38 ± 15.54 years were studied. High anti-TTG levels were seen in 36 (6.8%) patients, and duodenal pathologies were seen in 23 (4.5%) patients. Fifteen (2.8%) were diagnosed with CD based on both serology and biopsy. Bloating was the most common type of dyspepsia in CD patients (7, 46.7%), followed by epigastric pain (6, 40%), and postprandial fullness (2, 13.3%). Two CD patients (13.3%) reported a positive family history for CD. Logistic regression model showed that iron deficiency anemia (IDA), anti-TTG level, and Helicobacter pylori infection were predictors of histological changes of CD, whereas IDA was the only independent predictor of CD in dyspeptic patients ( OR = 17.65 , 95 % CI = 1.53 ‐ 202.52 , and P = 0.021 ). Conclusion. CD is prevalent in dyspeptic patients, but routine biopsy from normal-appearing duodenal mucosa is not recommended for all patients. Serological studies, complete history, and careful endoscopic evaluation may provide better cost-effective clinical solutions to improve the diagnostic yield of celiac disease in dyspeptic patients.

scholarly journals Animal-related injuries and fatalities: evidence from a large-scale population-based cross-sectional survey in rural Bangladesh

BMJ Open ◽  
2019 ◽  
Vol 9 (11) ◽  
pp. e030039
Author(s):  
Md Al Amin Bhuiyan ◽  
Priyanka Agrawal ◽  
Shirin Wadhwaniya ◽  
Qingfeng Li ◽  
O Alonge ◽  
...  
Keyword(s):  
Large Scale ◽  
Age Groups ◽  
Population Based ◽  
Secondary Outcome ◽  
Public Health Issue ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Rural Bangladesh ◽  
Snake Bites ◽  
Reported Data

ObjectiveThis study determines the magnitude and pattern of animal-related injury mortalities and morbidities in rural Bangladesh.Design and settingA cross-sectional survey was conducted in 51 Unions of 7 subdistricts of Bangladesh from June 2013 to September 2013.ParticipantsA total of approximately 1.17 million individuals across all age and gender profiles were included in the survey. The participants had to be residents of the seven subdistricts and have provided consent to participate in the study.Primary and secondary outcome measuresAnimal-related injury characteristics and demographic information was collected in the study. Frequency, proportion and 95% CIs of variables such as type of animal, type of animal attack, activity of the person prior to attack and the seasonality of the injury were reported. Data was then statistically analysed for associations between injury and sociodemographic characteristics.ResultsThe incidence rate of fatal and non-fatal animal-related injuries across all ages were 0.7 (95% CI 0.4 to 1.4) and 1635.3 (95% CI 1612.0 to 1658.0) per 100 000 populations, respectively. Non-fatal animal-related injury rates were highest among adults 18 years and older (1820.6 per 100 000 population (1777.2 to 1865.1)), and in males across all age groups. The most common animal injury was wasp/hornet/bee sting (49%), followed by cow/buffalo (25%), dog bite (9%) and snake bites (9%).ConclusionsAnimal-related injuries are an important public health issue in rural Bangladesh. The incidence of animal-related morbidities was found high in the study area. Males, school-going and productive age groups were at high risk. Immediate attention should be given to prevent these events.

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