scholarly journals An electrophysiological assessment of subclinical lead toxicity in children

2017 ◽  
Vol 6 (1) ◽  
pp. 23-26
Author(s):  
Mohammad Sayeed Hassan ◽  
Sheikh Farjana Sonia ◽  
Ferdous Ara ◽  
Md Abdullah Yusuf ◽  
Ahmad Raihan Sharif ◽  
...  

Background: While heavy exposure to inorganic lead is capable of inducing symptomatic neuropathy, subclinical neuropathy due to low level of lead exposure remains to be proved.Objectives: This study was assessed peripheral nerve function in environmental lead exposed primary school children.Methods: Electrophysiological evaluation of peripheral nerve function was done in 17 subclinical lead exposed and 17 non-exposed primary school children in an urban industrial area of Dhaka. Lead exposed children had mean blood lead level (BLL) 20.2 (±5.17) ?gm/ dl. Non-exposed children had BLL 6.2 (±2.82) ?gm/ dl.Results: Electrophysiological evaluation of peripheral nerve function was normal in lead exposed children. Statistical analysis also did not show any significant difference in parameters of nerve function between lead exposed and non-exposed children (p value >0.05).Conclusion: This study did not find any electrophysiological evidence of peripheral nerve dysfunction in the environmental lead exposed children compared to nonexposed.J Shaheed Suhrawardy Med Coll, June 2014, Vol.6(1); 23-26

2013 ◽  
Vol 25 (1) ◽  
pp. 1-5
Author(s):  
MS Hassan ◽  
MKK Patwary ◽  
MM Rahman ◽  
SF Sonia ◽  
M Kabiruzzaman ◽  
...  

Lead poisoning is one of the burning issues in Bangladesh. This study assessed the relation of blood lead level with IQ and peripheral nerve function in environmental lead exposed primary school children in Dhaka.Blood lead level (BLL) was measured in 84 primary school children in an urban industrial area of Dhaka. IQ was measured with Wechsler Intelligence Scales- Revised for children. Electrophysiological evaluation was done in 31 children.Verbal, Performance and Full scale IQ had a negative correlation with blood lead level (p<0.001). Decrement in Verbal, Performance and Full scale IQ associated with 1 microgram per deciliter increase in blood lead level were 0.99, 0.86 and 0.95 respectively (p<0.001). None had clinical features of neuropathy. Statistical analysis also did not show any significant difference in NCS between children with normal and elevated BLL (p value >0.05).It was found that IQ of children decreased in a linear trend with increasing blood lead level. This study did not find any clinical or electrophysiological evidence of peripheral nerve dysfunction in the environmental lead exposed children. DOI: http://dx.doi.org/10.3329/medtoday.v25i1.15899 Medicine Today 2013 Vol.25(1): 1-5


Author(s):  
Hussein Rizal ◽  
Mawar Siti Hajar ◽  
Ayu Suzailiana Muhamad ◽  
Yee Cheng Kueh ◽  
Garry Kuan

Brain Breaks Physical Activity Solutions (BBPAS) is a web-based structured physical activity (PA) video that is specifically designed for school settings and can stimulate a student’s health and learning. The purpose of this study is to measure the effect of BBPAS on the stages of change, decisional balance, processes of change, self-efficacy and leisure-time exercise among Malay ethnic primary school children. A validated Malay version of three of the five constructs was derived with sound validity and was used in the present study. A total of 159 male and 163 female children aged 10 to 11 years old, mean (SD) = 10.53 (0.50), were recruited from two schools in Kelantan, Malaysia. Purposive sampling was used to divide the children into intervention (n = 177) and control (n = 145) groups. Children in the intervention group underwent BBPAS activity for an accumulated 30 min per week, while children in the control group were not involved in the BBPAS intervention. Mixed factorial analysis of variance (ANOVA) was used to examine the effect of BBPAS on the study variables. A mixed ANOVA showed significant changes (time effect) on cognitive process, F(1, 320) = 5.768, p-value = 0.017; behavioural process, F(1, 313) = 5.736, p-value = 0.017; and internal feeling, F(1, 312) = 6.050, p-value = 0.014. There was also a significant difference between groups on cons, F(1, 316) = 7.504, p-value = 0.007. A significant interaction effect was observed for stages of change, F(1, 319) = 7.861, p-value = 0.005; pros, F(1, 316) = 31.311, p-value = 0.001; internal feeling, F(1, 312) = 4.692, p-value = 0.031; and behavioural process, F(1, 313) = 7.312, p-value = 0.007. In conclusion, BBPAS was successful in improving four of the five constructs, and thus, should be recommended to be used in schools throughout Malaysia.


2018 ◽  
Vol 8 (2) ◽  
pp. 200
Author(s):  
RAHMITA YANTI

The main nutritional problems facing the Indonesian government one of Iodine deficiency disorders (IDD). West Sumatra province found the prevalence of enlarged adenoids school children is still high which ranges from 12% -44,1% and Total Goiter Rate also high in the coastal region. This study aims to determine the factors cause iodine deficiency disorder (IDD) and relationship to nutritional status of primary school children 36 Singgalang Tanah Datar.This type of research is Case Control. The study population are the all of primary school children 36 Singgalang Tanah Datar, aged 9-12 years who suffered goiter examined palpation. The sample consisted of 30 cases and 30 controls. Sampling was done by purposive sampling technique. Data were processed using univariate, bivariate with chisquare test.The research results revealed there is relationship IDD to nutritional status of primary school children 36 Singgalang Tanah Datar (p = 0,034 (95% CI: 1,2 to 11,4)), an related of iodine intake (p = 0,016 (95% CI: 1,5 -14,4)), goitrogenik intake (p = 0,039 (95% CI: 1,2-9,9)), the quality of salt (p = 0,038 (95% CI: 1,2 to 10,2)), socioeconomic status (p = 0,02 (95% CI: 1,4-11,8), and the level of parents knowledge (p = 0,039 (95% CI: 1,2 to 9,9)) with iodine deficiency disorder. While variable which is not related to iodine deficiency disorder is the parents education level p = 0,77 (p value> 0,05)This study concluded that there is relationship IDD to nutritional status and there are relationship iodine intake, goitrogenik, salt quality, socioeconomic status, and level of knowledge of parent with iodine deficiency disorder. Need for nutrition counseling conducted by the health promotion officers regularly about the importance of the use of iodized salt for children's growth and nutrition education in the family menu processing so as to improve the nutritional status of children at the household levelKeywords : Iodine deficiency disorder, nutritional status, school children


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Jana Müller ◽  
Charlotte Kreutz ◽  
Steffen Ringhof ◽  
Maximilian Koeppel ◽  
Nikolaus Kleindienst ◽  
...  

AbstractImpaired postural control is often observed in response to neurotoxic chemotherapy. However, potential explanatory factors other than chemotherapy-induced peripheral neuropathy (CIPN) have not been adequately considered to date due to primarily cross-sectional study designs. Our objective was to comprehensively analyze postural control during and after neurotoxic chemotherapy, and to identify potential CIPN-independent predictors for its impairment. Postural control and CIPN symptoms (EORTC QLQ-CIPN20) were longitudinally assessed before, during and three weeks after neurotoxic chemotherapy, and in three and six months follow-up examinations (N = 54). The influence of peripheral nerve function as determined by nerve conduction studies (NCS: compound motor action potentials (CMAP) and sensory action potentials (SNAP)), physical activity, and muscle strength on the change in postural control during and after chemotherapy was analyzed by multiple linear regression adjusted for age and body mass index. Postural control, CIPN signs/symptoms, and CMAP/SNAP amplitudes significantly deteriorated during chemotherapy (p < .01). During follow-up, patients recovered from postural instabilities (p < .01), whereas CIPN signs/symptoms and pathologic NCS findings persisted compared to baseline (p < .001). The regression model showed that low CMAP and high SNAP amplitudes at baseline predicted impairment of postural control during but not after chemotherapy. Hence, pre-therapeutically disturbed somatosensory inputs may induce adaptive processes that have compensatory effects and allow recovery of postural control while CIPN signs/symptoms and pathologic peripheral nerve function persist. Baseline NCS findings in cancer patients who receive neurotoxic chemotherapy thus might assist in delineating individual CIPN risk profiles more precisely to which specific exercise intervention programs could be tailor-made.


2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
D Austys ◽  
A Sprudzanaitė ◽  
R Arlauskas ◽  
R Stukas

Abstract Background A large number of primary school children have personal smartphones which enable them to communicate with lots of people and use social networks. However, social networking should not be accessible to primary school pupils due to existing age restrictions. Studies show that cell phones can be used to send offensive or sexual content to children or by them. This might have long-term effects on child's mental health and even provoke suicidal thoughts. While parents are able to control many aspects of children's life, we aimed to disclose parental attitudes towards use of mobile phones among children. Methods A total number of 619 parents of primary school children from middle-sized town of Lithuania participated in this study. Parents anonymously expressed their opinion to questions about personal cell phones usage among children. Distribution of participants was assessed according to social and demographic characteristics. Results Most of the respondents (79.8%) indicated that use of mobile phones might be harmful to children's health, 56.0% indicated that their children use social networks and every second child was registered by their parents (49.5%). Minority of the respondents (8.1%) thought that children (including children from other families) receive messages from strangers and communicate with them (2.1%). Similarly, very few of the respondents thought that children receive offensive (15.0%) or sexual (4.8%) content. Younger and lower educated parents registered their children to social networks more frequently (p-value less than 0.05). Lower educated parents more frequently indicated that offensive or sexual content can reach children via smartphones (p-value less than 0.05). Conclusions Majority of parents of primary school children thought that cell phones might be harmful to children's health but most of them did not pay attention to threats such as communication with strangers or transmission of sexual content. Key messages Only minority of parents of primary school children indicated communication with strangers or transmission of sexual content as threats induced by use of smartphones among children. Regardless that lower educated parents indicated awareness of content-related threats to children more frequently they registered their children to social networks more frequently as well.


Amyloid ◽  
2003 ◽  
Vol 10 (1) ◽  
pp. 17-24 ◽  
Author(s):  
Sachio Kobayashi ◽  
Hiroshi Morita ◽  
Teruko Asawa ◽  
Yo-Ichi Takei ◽  
Takao Hashimoto ◽  
...  

1990 ◽  
Vol 11 (4) ◽  
pp. 451-456 ◽  
Author(s):  
C VANDERZEE ◽  
T SCHUURMAN ◽  
R VANDERHOOP ◽  
J TRABER ◽  
W GISPEN

2002 ◽  
pp. 645-668
Author(s):  
H. Gerhard Vogel ◽  
Wolfgang H. Vogel ◽  
Bernward A. Schölkens ◽  
Jürgen Sandow ◽  
Günter Müller ◽  
...  

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