scholarly journals A Clinicopathological Study of Solitary Thyroid Nodule

2019 ◽  
Vol 31 (2) ◽  
pp. 85-88
Author(s):  
GHM Shahidul Haque ◽  
Md Jakir Hossain ◽  
Sabrina Haque ◽  
Md Anisur Rahman

Introduction:Common presentation of thyroid disorders is solitary nodule. A discrete swelling in an otherwise impalpable gland is termed as solitary nodule of thyroid. The majority of solitary thyroid nodules are benign. The incidence of malignancy is 10-20%, being more common in females with a mean age of 35 years.The object of the study was to identify the incidence of malignancy in solitary nodule thyroid which emphasizes on the early diagnosis and adequate treatment. Materials and Methods: The study was carried out in the department of ENT and Head-Neck Surgery of Rangpur Medical College Hospital, Rangpur and Shaheed Ziaur Rahman Medical College Hospital, Boruga in 50 patients with solitary thyroid nodule from July 2013 to June 2015. Results: The solitary thyroid nodules were seen in 1.76% of surgical admissions. The mean age of the incidence of solitary thyroid nodule is 35 years. The incidence of malignancy in solitary thyroid nodule is 18.51%. The solitary thyroid nodules were frequent in females than males in the ratio of 6.71:1. Conclusion: It is concluded from the present study that a remarkable proportion 10% of solitary thyroid nodules was malignant with females preponderance which emphasizes on the early diagnosis and adequate treatment. Medicine Today 2019 Vol.31(2): 85-88

2018 ◽  
Vol 6 (1) ◽  
pp. 293
Author(s):  
Palani V. ◽  
Reshma S.

Background: Thyroid nodules are common endocrine problem. A discrete swelling in an otherwise impalpable gland is termed as solitary nodule of thyroid. Solitary nodules have a high likelihood of being malignant. They should be characterized properly for optimum management. Aim of the study is to identify the incidence of malignancy in solitary nodule thyroid.Methods: A prospective study had been carried out from January 2018 to October 2018, in the Department of General surgery, ACS Medical College and Hospital, Chennai, India. Fifty patients, who presented with solitary thyroid swelling were examined clinically and confirmed after taking a detailed history and underwent thyroid surgery were included in this study. The histopathological reports were evaluated by standard statistical methods.Results: There were 50 cases of clinically detected solitary thyroid nodule with female preponderance more than males. The mean age of the incidence of solitary thyroid nodule is 35years. The incidence of malignancy in solitary thyroid nodule is 20%.Conclusions: It is concluded from the present study that 20% of solitary thyroid nodules are malignant, with female preponderance and a mean age of solitary thyroid nodule is 35years.


2018 ◽  
Vol 5 (6) ◽  
pp. 2279
Author(s):  
A. Manmadha Kishan ◽  
Kameshwari Prasad

Background: A solitary nodule may become cosmetically distressing to a patient and occasionally causes pressure symptoms. Less frequently, an autonomously hyper functioning single nodule may cause hyperthyroidism. However, in the greater proportion of patients the major concern relates to the potential of malignancy with in such a nodule. Objective of present study was to study prevalence of solitary thyroid nodule and evaluate the risk factors associated with occurrence of malignancy in a solitary nodule of thyroid.Methods: This is a prospective study of randomly selected patients with clinically palpable, solitary thyroid nodule diagnosed and treated at Prathima Institute of Medical Sciences Karimnagar. Total duration of study was two years, from 2010 October to 2012 September.Results: The prevalence was found to be 19.2% in the present study. Majority were females i.e. 86.7%. It was found that maximum i.e. 36% of the cases belonged to the age group of 21-30 years. Swelling of the thyroid region was present in all cases. 97% of the patients were found to be euthyroid. FNAC showed that majority had follicular neoplasm. Hemi-thyroidectomy was the most common method used in 62 cases. Cytology diagnosis as Follicular neoplasm was the most common indication of surgery in 34 cases. Follicular adenoma was the most common histopathological finding in 43% of the cases. Benign lesion was the most common lesion in both males and females. Papillary cancer was the most common. The sensitivity of FNAC was found to be 94%.Conclusions: FNAC is the gold standard for evaluation of solitary thyroid nodules with an accuracy of 94% in our study. Females are more commonly affected than Males. 11.4% of Solitary Thyroid nodules were malignant. Suspect malignancy at extremes of age. Malignant potential of solitary thyroid nodule after 6th decade is 50%.


2012 ◽  
Vol 30 (1) ◽  
pp. 44-47 ◽  
Author(s):  
MM Hussain ◽  
A Rahman ◽  
MR Abedin ◽  
MA Habib

Jejunogastric intussusception is an established complication following any type of gastroenterostomy. In its acute form it presents with abdominal pain and lump suggestive of obstruction. It is also a rare cause of haematemesis. Chronic and intermittent presentation has also been described. It is a surgical emergency in its acute form. Early diagnosis and prompt treatment is required to avoid mortality. We report here a case that had a history suggestive of recurrent symptoms and ultimately presented as an acute emergency in the emergency department of Dhaka Medical College Hospital, Dhaka, Bangladesh   DOI: http://dx.doi.org/10.3329/jbcps.v30i1.11366   J Bangladesh Coll Phys Surg 2012; 30: 44-47  


2019 ◽  
Vol 10 (05) ◽  
pp. 20737-20740
Author(s):  
Md Shazibur Rashid ◽  
Najnin Akter ◽  
Jahangir Alam Majumder ◽  
AHM Delwar ◽  
Md Golam Mustafa

Objectives: To determine the frequency of thyroid malignancy in clinically or zoographically multinodular goiter in patients undergoing thyroidectomy in Cumilla Medical College Hospital, Bangladesh. Methods: A cross sectional study was carried out at the department of Otolaryngology and Head Neck Surgery of Cumilla Medical College Hospital during the period from January 2016 to January 2019. This study includes all patients admitted and undergoing surgery with multinodular goiter. Results: Out of 146 patients 118 patients were female and 28 patients were male with female male ratio is 4.2:1. Out of 146 patients 13 patients were found histologically thyroid malignancy. Among them 8 patients were male and 5 patients were female. Papillary carcinoma was found in all cases.


1970 ◽  
Vol 6 (4) ◽  
pp. 486-490 ◽  
Author(s):  
UN Khadilkar ◽  
P Maji

Objective: To determine the incidence of various thyroid disorders manifesting as Solitary Thyroid Nodule and also to evaluate the histomorphology of the lesions. Materials and methods: Hundred specimens of Solitary Thyroid Nodules were studied for gross characteristics, microscopic features, age and sex incidence. Results: Of the 100 cases of Solitary Thyroid Nodules, 66% were non neoplastic and 34% were neoplastic. Among the neoplasms, 21% were malignant and 13% were benign. The age incidence ranged from 20-50 years for non neoplastic lesions and 20-40 years for neoplasms. A female preponderance was seen for both non neoplastic and neoplastic conditions. The solitary nodules involved the right side of the thyroid more commonly than the left. Involutional colloid nodule was the predominant type of solitary nodule (52%). Among the malignant neoplasms, papillary carcinoma was the commonest solitary nodule (13%). One case each of hyalinising trabecular adenoma, columnar cell variant of papillary carcinoma and medullary carcinoma unusually presenting as solitary nodules were encountered in the present study. Conclusion: Histomorphologic evaluation of Solitary Thyroid Nodules presenting without a background setting of multinodular goiter is challenging and mandatory as the diagnoses ranges from the common non neoplastic lesions like involuting nodules to the rare neoplastic conditions like medullary carcinoma. Key words: Solitary Thyroid Nodule morphology, involuting nodule, medullary carcinoma doi: 10.3126/kumj.v6i4.1740   Kathmandu University Medical Journal (2008), Vol. 6, No. 4, Issue 24, 486-490


2012 ◽  
Vol 18 (1) ◽  
pp. 16-22
Author(s):  
Mazharul Alam Siddique ◽  
Mahbuba Hossen ◽  
Ahmmad Taous ◽  
Kazi Shamimus Salam ◽  
Belayat Hossain Siddiquee ◽  
...  

Background: Congenital neck mass is a very common problem in children in Otolaryngology & Head-Neck Surgery and Paediatric Surgery Department but data of our country is inadequate and there is lack of published study. This study will help to diagnose congenital neck masses, evaluate the success of surgical treatment in our country.Objective: To assess the frequency of congenital neck mass in children and to see the clinical presentation of different congenital neck mass.Study design: Cross sectional prospective study.Place of study: Department of Otolaryngology – Head & Neck Surgery, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Dhaka Medical College Hospital (DMCH)l, Dhaka and Mymensingh Medical College Hospital (MMCH), Mymensingh.Methodology: Patients below the age of 18 years with congenital neck mass who presented to three tertiary level hospitals from January 2010 to December 2010 were included in this study. Total thirty six patients were purposively selected. Age, gender, types of swelling and location were examined, investigations were done. Data was analyzed with SPSS software and was presented in the form of tables, diagrams and pie charts.Results: 36 patients with different congenital neck swelling were examined. Out of 36 patients, thyroglossal cysts were commonest- 21(58.33%). Other congenital lesions were as follows: Branchial cyst 7(19.44), Lymphangioma 3(8.33%), Haemangioma 3(8.33%), Dermoid cyst 2(5.55%). Midline was most common location 21 (58.33%).Conclusion: Congenital neck masses constitute important differential diagnosis for neck masses. These masses constitute diagnostic and therapeutic challenges for many clinicians. Correct diagnosis, safe and complete surgical excision requires sound knowledge of the location and extent of these masses.   DOI: http://dx.doi.org/10.3329/bjo.v18i1.10409  Bangladesh J Otorhinolaryngol 2012; 18(1): 16-22


1970 ◽  
Vol 14 (2) ◽  
pp. 51-56
Author(s):  
Md Abu Yusuf Fakir ◽  
Md Arif Hossain Bhuyan ◽  
Md Mosleh Uddin ◽  
HM Mustafizur Rahman ◽  
Syed Hasan Imam Al-Masum ◽  
...  

Objective: To evaluate the clinical outcome, morbidity and mortality of patients diagnosed as Ludwig's angina. Study design: Retrospective study. Setting: Department of Otolaryngology & Head and Neck Surgery, Dhaka Medical College Hospital and Apollo Hospitals Dhaka. Patients and Methods: 50 patients were included in this study (36 males and 14 female) between the ages of 8 and 78 years (mean, 45.5 years) who were treated between January 2007 and December 2008 in the department of Otolaryngology and Head-Neck surgery, Dhaka Medical College Hospital and Apollo Hospitals Dhaka. Etiology, microbiology, associated systemic diseases, treatment, airway management, duration of hospital stay and outcome were reviewed. Results: Most common age group was 3rd decade (42%) and 72% patients were male. Most patients came from poor socio-economic condition and rural area of Bangladesh. 100% patients presented with neck swelling, pain, tenderness and fever. Dental infection was documented as the most common cause (70%) of Ludwig's angina, followed by infection of the tonsils (10%) and submandibular gland (6%). Systemic illnesses included diabetes mellitus (30%) and chronic renal failure (4%).Streptococcus is commonest organism found in culture of pus. Intravenous antibiotics were started immediately in all patients. 4 patients underwent emergency tracheostomy. 40 patients underwent incision and drainage. Infected tooth/ teeth were also removed at the same time. Postoperatively, the airway was secured by endotracheal intubation in 1 case and by tracheotomy in 5 cases. In 88 %( 44 patients) of the cases, no artificial airway was used. 9 patients were managed in the intensive care unit for 1 to 3 days. All except 1 patient made uneventful recoveries and they were discharged after 3 to 26 days of hospitalization (mean, 14.1 days). Conclusion: Airway protection, aggressive antibiotic therapy and surgical decompression can significantly alter the mortality rate of Ludwig's angina. Key Words: Cellulitis, Ludwig's angina, surgical decompressionDOI: 10.3329/bjo.v14i2.3281 Bangladesh J of Otorhinolaryngology 2008; 14(2) : 51-56


2016 ◽  
Vol 21 (2) ◽  
pp. 85-89
Author(s):  
Md Nazmul Islam ◽  
Dipankar Lodh ◽  
Mohammad Mamun Siddiqui ◽  
AF Mohiuddin Khan ◽  
Kazi Meherunnesa

A Cross-Sectional Study was carried out from July 2006 to June 2007 at Department of Otolaryngology and Head-Neck Surgery of Dhaka Medical College Hospital, Dhaka. Data was collected from 150 patients with histologically diagnosed Hypopharyngeal carcinoma. Results of this study showed that hypopharyngeal carcinoma affects more in fifth (36.7%) and sixth (27.4%) decades of life. It was found that male were highly predominant to develop hypopharyngeal carcinoma and male female ratio was 9:1. People with lower educational level were found to be affected more by hypopharyngeal carcinoma. In this study 86 percent patients had history of smoking. Mean duration of smoking was 38.0±23.6 years. This study found that the key symptoms of hypopharyngeal carcinoma was dysphagia, pain and neck mass. In this study 83.5 percent patients presented with palpable lymph node and most (76.6%) of them were in level II. Pyriform fossa was found to be the commonest site (83.3%). In this study all malignancy in hypopharynx was histopathologically squamous cell carcinomaBangladesh J Otorhinolaryngol; October 2015; 21(2): 85-89


1970 ◽  
Vol 17 (2) ◽  
pp. 104-109
Author(s):  
Md Golam Mustafa ◽  
Khabiruddin Ahmed ◽  
Mahmudal Hasan

Objective: To study the quality of life in patient who underwent ESS operation. Design and setting: A prospective study conducted over a period of one(01) year; from July 2004 to June 2005 in Otolaryngology – Head & Neck Surgery Department of Shaheed Suhrawardy Medical College Hospital and Dhaka Medical College Hospital, Dhaka, Bangladesh. Results: Hospital admitted 60(Sixty) cases of ESS patients were included and analyzed. 42 cases were male; whereas 18 cases were female in this study. 21-40 years (44 cases) were the commonest age group of study people. No significant/ alarming complications were recorded during post operative period. Conclusion: Instead of all limitations, outcome of ESS is more acceptable in comparison with conventional sinus surgery. The main symptoms, like nasal obstruction, discharge, headache and facial pain get relieved off dramatically which is compatible with other recognized study. Key words: Endoscopic sinus surgery; open the sinuses; restore normal air flow. DOI: http://dx.doi.org/10.3329/bjo.v17i2.8849 BJO 2011; 17(2): 104-109


2020 ◽  
Vol 22 (2) ◽  
pp. 110-117
Author(s):  
Md Mahmudul Islam ◽  
Khondkar AK Azad ◽  
Md Aminul Islam ◽  
Rivu Raj Chakraborty

Background: Chest trauma is responsible for 50% of deaths due to trauma. This kind of death usually occurs immediately after the trauma has occurred. Various therapeutic options have been reported for management of chest injuries like clinical observation, thoracocentesis, tube thoracostomy and open thoracotomy. Objective: To observe the pattern and outcome of management in chest trauma Methods: This is an observational study carried out in Casualty department of Chittagong Medical College Hospital (CMCH), Chittagong, between April 2015 to March 2016. Our study was included all patients, both sexes, following chest injury at Casualty units of Chittagong Medical College Hospital. All the data were recorded through the preformed data collection sheet and analyzed. Result: The mean age was found 37.7±18.1 years with range from 12 to 80 years. Male female ratio was 11.8:1. The mean time elapsed after trauma was found 6.1±3.1 hours with range from 1 to 72 hours. Almost one third (35.7%) patients was affecting road traffic accident followed by 42(27.3%) assault, 35(22.7%) stab injury, 15(9.7%) fall and 7(4.5%) gun shot . More than three fourth (80.5%) patients were managed by tube thoracostomy followed by 28(18.2%) observation and 2(1.3%) ventilatory support. No thoracotomy was done in emergency department. 42(27.2%) patients was found open pneumothorax followed by 41(26.6%) rib fracture, 31(20.1%) haemopneumothorax, 14(9%) simple pneumothorax, 12(7.8%) haemothorax, 6(3.9%) chest wall injury, 5(3.2%) tension pneumothorax, and 3(1.9%) flail chest. About the side of tube 60(39.0%) patients were given tube on left side followed by 57(37.0%) patients on right side, 9(5.8%) patients on both (left & right) side and 28(18.2%) patients needed no tube. Regarding the complications, 13(30%) patients had persistent haemothorax followed by 12(29%)tubes were placed outside triangle of safety, 6(13.9%) tubes were kinked, 6(13.9%) patients developed port side infection, 2(4.5%)tube was placed too shallow, 2(4.5%) patients developed empyema thoracis and 2(4.5%) patients developed bronchopleural fistula. The mean ICT removal information was found 8.8±3.6 days with range from 4 to 18 days. Reinsertion of ICT was done in 6(4.7%) patients. More than two third (68.2%) patients were recovered well, 43(27.9%) patients developed complication and 6(3.9%)patients died. More than two third (66.9%) patients had length of hospital stay 11-20 days. Conclusion: Most of the patients were in 3rd decade and male predominant. Road traffic accident and tube thoracostomy were more common. Open pneumothorax, rib fracture and haemopneumothorax were commonest injuries. Nearly one third of the patients had developed complications. Re-insertion of ICT needed almost five percent and death almost four percent. Journal of Surgical Sciences (2018) Vol. 22 (2) : 110-117


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