scholarly journals A Demographic Study on Oral Non Squamous Cell Malignant Tumors

2014 ◽  
Vol 3 (2) ◽  
pp. 34-38
Author(s):  
Md Amirul Islam ◽  
Md Shahjahan Ali ◽  
Md Mahfuz Hossain ◽  
Md Nazmul Hasan ◽  
Tazdik G Chowdhury
Keyword(s):  
Malignant Melanoma ◽  
Salivary Glands ◽  
Squamous Cell ◽  
Clinical Presentation ◽  
Malignant Tumors ◽  
Maxillofacial Surgery ◽  
Malignant Neoplasm ◽  
Minor Salivary Glands ◽  
Female Ratio ◽  
Oral Malignancies

Background: Nonsquamous cell malignant tumors of jaw and oral soft tissue are rare constituting between 6%-10% of all malignancies in the region. A few case reports of individual tumors are available while reviews of significant series is lacking. This report presents 22 cases of Nonsquamous cell malignant tumors collected over 8 months at a tertiary oral care centre in Dhaka, Bangladesh. Objective: To find out the distribution & pattern of oral nonsquamous cell malignant tumors among all oral malignancy and to find out the age, sex, site, clinical presentation, the histological types of these tumors. Method: This descriptive cross sectional study was done in Oral and Maxillofacial Surgery Department, Dhaka Dental College and Hospital.The entire patient histopathologically diagnosed as any type of Nonsquamous cell tumor were selected. Data were collected in a summarized data sheet. Then histopathological types of them were analyzed to indicate the distribution according to age, gender, site and clinical presentation. Result: There were 107 Oral malignancies of which 22(20.56%) were Nonsquamous cell malignant tumors which is significant in comparison to Squamous cell carcinoma in Bangladesh. Among the respondents, 9(40.91%) were diagnosed as minor salivary glands malignant tumors, 7(31.2%) were diagnosed as sarcomas, Malignant melanoma were 4(18.18%) and Non- Hodgkin’s lymphoma were 2(9.09%). The male to female ratio was 1:1.2 with ages were between 9 years to 70 years old (mean age 35.45 ± 21.76 years) with most patients (36.36%) in 16 to 30 years of life. Cases presented with symptoms such as swelling (100%), pain, paresthesia, loose tooth and tissue ulceration. Conclusion: In Dhaka Dental College Hospital, nonsquamous cell malignant tumors account for 20.56% of all oral malignancies among them minor salivary glands malignant neoplasm and malignant melanoma were the predominant type. Most affected were people in the 2nd and 3rd decades of life with no sex predilection. Most common site of involvement was maxilla. The need for improved medical awareness, diagnostic facilities and upgrading of infrastructure was stressed. DOI: http://dx.doi.org/10.3329/updcj.v3i2.17997 Update Dent. Coll. j: 2013; 3 (2): 34-38

Endoscopic Transnasal Resection of Ectopic Esthesioneuroblastoma in the Pterygopalatine Fossa: Technical Case Report

2009 ◽  
Vol 65 (suppl_6) ◽  
pp. onsE112-onsE113 ◽  
Author(s):  
Satoru Kodama ◽  
Toshiaki Kawano ◽  
Masashi Suzuki
Keyword(s):  
Clinical Presentation ◽  
Malignant Tumors ◽  
Malignant Neoplasm ◽  
Complete Removal ◽  
Pterygopalatine Fossa ◽  
Open Approach ◽  
Transnasal Approach ◽  
Olfactory Neuroepithelium ◽  
Endoscopic Transnasal Approach ◽  
Left Maxillary Sinus

Abstract Objective: Esthesioneuroblastoma is a rare, malignant neoplasm arising from the olfactory neuroepithelium in the upper nasal cavity. Even more rare is ectopic esthesioneuroblastoma developing from the region outside the olfactory epithelium. In addition, tumors occurring in the pterygopalatine fossa (PPF) are uncommon, and the endoscopic transnasal approach for the resection of malignant tumors in this region is also uncommon. Clinical Presentation: We describe an esthesioneuroblastoma arising from the left maxillary sinus and PPF. The tumor was resected using the endoscopic transnasal approach, followed by treatment with radiotherapy. The patient showed no evidence of recurrence 12 months postoperatively. Technique: The endoscopic transnasal approach could be successfully used for the complete removal of malignant tumors in the PPF. Conclusion: The PPF is an anatomic area that is difficult to access. The endoscopic transnasal approach improves access and visualization; it also has the potential to reduce complications compared with the open approach. The endoscopic transnasal approach might become the treatment of choice for malignant tumors in the PPF.

End Results of Surgical Treatment of 622 Cases of Tumors of the Salivary Glands.

1974 ◽  
Vol 60 (4) ◽  
pp. 307-316 ◽  
Author(s):  
Carmelo Vinicio Catania ◽  
Emanuele Galante ◽  
Gaetano Bandieramonte ◽  
Bruno Salvadori
Keyword(s):  
Salivary Glands ◽  
Radical Surgery ◽  
Malignant Tumors ◽  
Survival Rates ◽  
High Rate ◽  
Surgical Removal ◽  
Minor Salivary Glands ◽  
Benign Lesions ◽  
Submandibular Glands ◽  
Mixed Tumors

Surgery was performed on 622 patients with tumors of the salivary glands from 1929 to 1972; the gland affected was the parotid in 527 cases, the submandibular glands in 50, and minor salivary glands of palate and other sites in 45. The analysis of distant results point out that both for benign and malignant tumors total sialoadenectomy must be the treatment of choice, as demonstrated by the high rate of recurrence after local excision or partial resection of the gland, even in cases of surely benign lesions such as mixed tumors. It is worthy of being quoted the high rate of recurrence from cylindromas, especially of the palate (48.5%), after surgical removal. As to malignancies of parotid and submandibular glands 5-years survival rates after radical surgery were of 52 % and 30 % respectively.

scholarly journals Nasopharyngeal Hyalinizing Clear Cell Carcinoma: A Case Report and Review of the Literature

2019 ◽  
Vol 10 ◽  
pp. 215265671988903 ◽  
Author(s):  
Madison J. Malfitano ◽  
Meghan N. Norris ◽  
Wesley H. Stepp ◽  
Griffin D. Santarelli ◽  
T. Danielle Samulski ◽  
...  
Keyword(s):  
Case Report ◽  
Salivary Glands ◽  
Clear Cell ◽  
Malignant Tumors ◽  
Treatment Strategies ◽  
Low Grade ◽  
Minor Salivary Glands ◽  
Presenting Symptoms ◽  
Nasopharyngeal Mass ◽  
The Right

Background Hyalinizing clear cell carcinomas (HCCCs) are rare, low-grade, malignant tumors which most often arise from the minor salivary glands primarily in palate and tongue but can arise in any location with minor salivary glands including the nasopharynx. Methods A case report of primary nasopharyngeal HCCC is presented. Because of the rarity of this tumor and location, a literature search was conducted to determine the most common presenting symptoms, treatment strategies, and outcomes. Results A 48-year-old man underwent biopsy of a 4.5 cm mass of the right nasopharynx with pathology suggesting an intermediate grade mucoepidermoid carcinoma. After discussing management with the patient, an endoscopic resection was performed. Final pathology revealed an HCCC which was confirmed after negative Mastermind-like 2 (MAML2) and positive Ewing sarcoma breakpoint region 1 (ESWR1) gene rearrangements on fluorescence in situ hybridization (FISH) studies. Literature review of other nasopharyngeal HCCC cases shows diverse presentation and overall excellent prognosis through surgical and radiation therapy. Conclusion HCCCs are rare, low-grade malignant tumors of the minor salivary glands and can present as a nasopharyngeal mass. Presenting symptoms are diverse but frequently involve otologic and sinonasal disturbances. HCCC is an indolent tumor with an excellent prognostic outcome when treated appropriately with surgical resection and adjuvant radiotherapy.

scholarly journals Cheilitis Glandularis of Both Lips: Successful Treatment with a Combination of an Intralesional Steroid Injection and Tacrolimus Ointment

2018 ◽  
Vol 2018 ◽  
pp. 1-3
Author(s):  
Norberto Sugaya ◽  
Dante Migliari
Keyword(s):  
Salivary Glands ◽  
Successful Treatment ◽  
Clinical Presentation ◽  
Steroid Injection ◽  
Inflammatory Condition ◽  
Minor Salivary Glands ◽  
Successful Management ◽  
Tacrolimus Ointment ◽  
Intralesional Steroid ◽  
Intralesional Steroid Injection

Cheilitis glandularis (CG) is an inflammatory condition of unknown cause that predominantly affects the minor salivary glands of the lips. Although a diagnosis of CG is not difficult, its treatment is a challenge. This article highlights the clinical presentation of the disease together with a case of successful management of this disease using a combination of a steroid injection followed by a topical immunosuppressor.

Clinico-epidemiologic review of 91 cases of non-odontogenic sarcomas of the orofacial region in a Nigerian population

2019 ◽  
Vol 8 (2) ◽  
pp. 25-31 ◽  
Author(s):  
ROWLAND AGBARA ◽  
BENJAMIN FOMETE ◽  
KELVIN OMEJE ◽  
POLYCARP ONYEBUCHI
Keyword(s):  
Malignant Tumors ◽  
Maxillofacial Surgery ◽  
Osteogenic Sarcoma ◽  
University Teaching ◽  
Oral And Maxillofacial Surgery ◽  
Female Ratio ◽  
Oncological Treatment ◽  
Orofacial Region ◽  
Surgery Department

Introduction: Sarcomas are a rare group of malignant tumors. This study highlights important findings in 91 cases of non-odontogenic sarcomas of the orofacial region. Materials and Methods: Patients who presented with orofacial sarcoma at the Oral and Maxillofacial Surgery Department of a regional University Teaching Hospital between January 1997 and June 2017 were retrospectively studied. Excluded were cases of Kaposi and odontogenic sarcomas. Data obtained were analyzed using the Statistical Package for Social Sciences (SPSS) version 16 (SPSS Inc., Chicago, IL, USA). Results from descriptive statistics were represented in the form of charts. Results: A total of 91 cases were reviewed and consisted of 51 (56.0%) males and 40 (44.0%) females, with a male to female ratio of 1.3:1. The mandible (n=47; 51.6%) and the maxilla (n=26; 28.6%) were the major sites involved. Osteogenic sarcoma (n=44; 48.4%) and rhabdomyosarcoma (n=16; 17.6%) occurred more frequently. A total of 41 (45.1%) patients had surgery and the common hard tissue procedures were mandibulectomy (n=26; 28.6%) and maxillectomy (n=10; 11.0%). Non-surgical oncological treatment was administered to 32 (35.2%) patients, and this was the only modality of treatment in 8 (8.8%) cases. The period of follow-up Arranged from 1-43 months and within this period; there were 7 (17.1%) recurrences with 1 case of pulmonary metastasis. Discussion: Most recurrences were noted less than one-year post-treatment. There is a tendency for patients to present late and compliance with follow up review is poor in this environment.

scholarly journals Clinical Presentation and Histological Variation of Pleomorphic Adenoma of Salivary Glands

2019 ◽  
Vol 37 (2) ◽  
pp. 72-77
Author(s):  
Md Nazmul Hasan Khandker ◽  
SM Anwar Sadat ◽  
Tarin Rahman ◽  
Ismat Ara Haider ◽  
Mohiuddin Ahmed
Keyword(s):  
Salivary Gland ◽  
Salivary Glands ◽  
Pleomorphic Adenoma ◽  
Clinical Presentation ◽  
Maxillofacial Surgery ◽  
Mouth Opening ◽  
Morphological Characteristics ◽  
Salivary Gland Tumour ◽  
Frequent Pattern ◽  
Gland Tumour

Background: Pleomorphic Adenoma is the most common salivary gland tumour accounts 40-70% of all salivary gland tumour and about 60-80% of the benign tumours and 60- 70% of all parotid tumours. There is no study conducted in Bangladesh to observe the clinical and histological variation of the tumour. This study presents 36 cases of Pleomorphic adenoma collected over 11 months at the different territory hospital of Dhaka city. Design: Observational study (November’ 2011 to September’ 2012) Setting: Department of Oral and Maxillofacial Surgery (Dhaka Dental College and Hospital, Bangabandhu Sheikh Mujib Medical Universityl), Department of ENT and Head- Neck Surgery (Dhaka Medical College and Hospital, Bangabandhu Sheikh Mujib Medical University). Method: The entire patient clinically and cytologically diagnosed as Pleomorphic adenoma were selected. Data were collected in a summarized data sheet. Then histopathological types of them were analyzed from excisional biopsized tissue. Result: There were 36 patients of Pleomorphic adenoma of which 24(66.67%) in Parotid glands, 4(11.11%) in Submandibular glands and 8(22.22%) in minor salivary glands. Among the respondents, female was predominant 20(55.56%) with ages were between 29 years to 65 years old (mean age 44.83 ± 8.32 years) with most patients (44.44%) in 41 to 50 years of life. In histophathological study showed Stromal rich 38.89%, cell rich 36.11% and classic 25%. Cuboidal cells were the most commonly found cellular type followed by plasmacytoid and spindle.Trabeculae and duct like structures were the most frequent pattern by the epithelial cells.Myxoid and Hyalinization were the most frequently found mesenchymal like tissue.Cases presented with symptoms such as swelling (100%), limitation of mouth opening, paesthesia and pain. Conclusion: The knowledge about clinical presentation and the immense variety of cells, architectures and morphological characteristics present in Pleomorphic adenoma of the salivary gland is essential for correct diagnosis and prognosis. The need for improved diagnostic facilities and upgrading of infrastructure was stressed. J Bangladesh Coll Phys Surg 2019; 37(2): 72-77

scholarly journals Atypical presentation of adenosquamous carcinoma: A case report

2018 ◽  
Vol 6 ◽  
pp. 2050313X1880121
Author(s):  
Annie Genois ◽  
Catherine Maari ◽  
Danielle Bouffard
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Clinical Presentation ◽  
Adenosquamous Carcinoma ◽  
Malignant Neoplasm ◽  
Atypical Presentation ◽  
Rare Tumour ◽  
The Past ◽  
Prompt Diagnosis

Cutaneous adenosquamous carcinoma is a rare malignant neoplasm that is more aggressive than conventional squamous cell carcinoma. The typical clinical presentation is an indurated papule or plaque on the head and neck of elderly patients. The authors report the case of a 52-year-old man with a right scrotal and inguinal tumour measuring 10 cm × 15 cm that had progressed over the past 2 years. The histological examination was compatible with adenosquamous carcinoma. Metastatic inguinal and pelvic lymph nodes were identified. This case demonstrates an atypical presentation of a rare tumour. Adenosquamous carcinoma is more aggressive than conventional squamous cell carcinoma, and prompt diagnosis is important.

Surgery for Malignant Tumors of the Minor Salivary Glands

2019 ◽  
pp. 97-122
Author(s):  
Davide Lombardi ◽  
Remo Accorona ◽  
Davide Lancini ◽  
Vittorio Rampinelli ◽  
Anna Bozzola ◽  
...  
Keyword(s):  
Salivary Glands ◽  
Malignant Tumors ◽  
Minor Salivary Glands

Decreasing Incidence of Malignant Tumors of the Paranasal Sinuses in Sweden

2003 ◽  
Vol 112 (3) ◽  
pp. 236-241 ◽  
Author(s):  
Tomas Norlander ◽  
Claes Silfverswärd ◽  
Jan-Erik Frödin ◽  
Anders Änggård
Keyword(s):  
Paranasal Sinus ◽  
Squamous Cell ◽  
Malignant Tumors ◽  
Squamous Cell Carcinomas ◽  
Sphenoidal Sinus ◽  
Female Ratio ◽  
Adjusted Incidence Rate ◽  
Poorly Differentiated ◽  
Male Patients ◽  
Adjusted Incidence

We reviewed 141 cases of paranasal sinus tumors treated at Karolinska Hospital from 1960 to 1980. Of these tumors, 100 were located in the maxillary sinus, 32 in the ethmoidal sinuses, 8 in both the ethmoidal and maxillary regions, and 1 in the sphenoidal sinus. The male-to-female ratio was 2.1 to 1. Squamous cell carcinoma and adenocarcinoma were the most frequent types of tumors (55% and 13%, respectively). Treatment included surgery, irradiation, or both. The 5-year survival rate was 34% for squamous cell carcinomas and 64% for adenocarcinomas. When compared to a previous material of patients treated at the same hospital from 1940 to 1950, the proportion of poorly differentiated squamous cell carcinomas had increased significantly. The age-adjusted incidence rate decreased from 1.2 to 0.4 for male patients and from 0.7 to 0.3 for female patients between 1960 and 1980. We conclude that the incidence of malignant paranasal sinus tumors has decreased, and that squamous cell tumors now seem to be generally less differentiated than they were 50 years ago.

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