scholarly journals Potencial Evocado Auditivo Mismatch Negativity em músicos e não músicos: Revisão sistematica

2021 ◽  
Vol 10 (1) ◽  
pp. e59610112170
Author(s):  
Ainoã Ruthy Farias Silva Veras ◽  
Ysa Karen Santos Macambira ◽  
Ruth Raquel Soares de Farias

O potencial evocado de longa latência Mismatch Negativity (MMN) se refere de forma objetiva como método eletrofisiológico às habilidades de discriminação sonora, processamento auditivo, memória auditiva e atenção involuntária em nível central. Tais habilidades são encontradas de maneira distinta entre músicos e não músicos e o MMN é utilizado de forma objetiva para detecta-las. Objetivo: realizar uma revisão sistemática para verificar se existe diferenças de latência e amplitude apresentadas por meio do MMN em músicos e não músicos. Método: A pesquisa foi realizada entre setembro e novembro de 2020, nas bases eletrônicas Pubmed, ScienceDirect, BVS (Lilacs), Scopus, Circumpolar Health Bibliographic Database, SciELO, Embase, Web of science e Cochrane Central Register of Controlled Trials (CENTRAL), bem como as bases de literatura cinzenta OpenGrey.eu, DissOnline, The New York Academy of Medicine, Clinical Evidence e Clinical Trials, utilizando os descritores da seguinte forma Music OR musician OR musicians AND potencial mismatch negavitity OR MMN OR evoked potentials auditory OR Long Latency. Resultados: Foram encontrados 9 artigos , sendo que 7 abordavam que os músicos superavam os não músicos em suas latências e amplitudes de MMN, em contraste 2 artigos não diferenciavam as latências e amplitudes entre músicos e não músicos. Conclusão: Os músicos apresentaram em uma grande maioria dos estudos uma superioridade aos não músicos em amplitude, o que significa que as habilidades neurais de discriminação auditiva e comportamentais dos músicos superam aos de não músicos, os músicos apresentaram menor latência de MMN ainda assim superando os não músicos.

2021 ◽  
Vol 10 (1) ◽  
pp. e43110111969
Author(s):  
Kyvia Magalhães Carvalho ◽  
Ysa Karen Santos Macambira ◽  
Ruth Raquel Soares de Farias

O potencial evocado miogênico vestibular ocular possui reflexo a partir de músculos extraoculares, em resposta a sons de elevada intensidade. O VEMP ocular avalia a via vestibular superior e a via contralateral ascendente, através do reflexo vestíbulo-ocular. Caracterizada por breves episódios de vertigem, náuseas e/ou nistagmo de posicionamento à mudança de posição da cabeça, a VPPB é provocada pela presença inapropriada de partículas de estatocônios advindas da mácula utricular flutuantes na endolinfa do(s) canal(is) semicircular(es) ou aglutinados à cúpula do(s) mesmo(s). O presente estudo tem como objetivo verificar se os valores de latência e amplitude dos componentes do oVEMP são diferentes em pacientes com VPPB quando comparados com adultos normais.  O estudo trata-se de uma revisão sistemática, onde buscou investigar os valores de latência e amplitude do oVEMP em VPPB e grupo controle, pesquisado nas seguintes bases de dados: PubMed, ScienceDirect, BVS (lilacs), SciELO, Scopus, Circumpolar Health Bibliographic Database, Embase, Web of Science e Cochrane Central Register of Controlled Trials (CENTRAL). Além das bases de literatura cinzenta: OpenGrey, DissOnline, The New York Academy of Medicine, ClinicalEvidence.com e ClinicalTrials.gov. Nos estudos observa-se que as médias de latência n1 e p1 em indivíduos com VPPB e controle saudáveis não mostraram diferenças entre sim, caracterizando como respostas normais. Enquanto, os dados de amplitude n1 e p1 em indivíduos com VPPB foi menor quando comparados com grupo controle. Os achados apontam a relevância do enfoque e validam o estudo, uma vez que os resultados do grau de latência e amplitude podem sugerir alterações desencadeadas pela VPPB. Sendo então o teste oVEMP o mais eficiente para avaliar os casos com VPPB.


2020 ◽  
pp. jrheum.200307
Author(s):  
Hao Deng ◽  
Bao Long Zhang ◽  
Jin Dong Tong ◽  
Xiu Hong Yang ◽  
Hui Min Jin

Objective To assess whether febuxostat use increases the risk of developing cardiovascular events, death from cardiac-cause and all-cause mortalities. Methods The relevant literature was searched in several databases including the MEDLINE (PubMed, 1 Jan. 1966–29 Feb. 2020), Web of science, EMBASE (1 Jan. 1974–29 Feb. 2020), ClinicalTrials.gov and Cochrane Central Register for Controlled Trials. Manual searches for references cited in the original studies and relevant review articles were also performed. All studies included in this metanalysis were published in English. Results In the end, 20 studies that met our inclusion criteria were included in this meta-analysis. Use of febuxostat was found not to be associated with an increased risk of all-cause mortality (RR = 0.87, 95% CI 0.57–1.32, P =0.507). Also, there was no association between febuxostat use and mortalities arising from cardiovascular diseases (CVD) (RR = 0.84, 95% CI 0.49–1.45, P=0.528). The RR also revealed that febuxostat use was not associated with CVD events (RR = 0.98, 95% CI 0.83–1.16, P =0.827). Furthermore, the likelihood of occurrence of CVD events was found not to be dependent on febuxostat dose (RR = 1.04, 95% CI 0.84–1.30, P =0.723). Conclusion Febuxostat use is not associated with increased risks of all-cause mortality, death from CVD or CVD events. Accordingly, it is a safe drug for the treatment of gout. Systematic review registration: PROSPERO CRD42019131872


Author(s):  
Francisca Jane Gomes de Oliveira ◽  
Andrea Bezerra Rodrigues ◽  
Islane Costa Ramos ◽  
Joselany Áfio Caetano

Objective: to analyze the evidence available in the literature about the lowest necessary dose of heparin to maintain the patency of the totally implanted central venous catheter in adult cancer patients. Method: an integrative literature review, carried out in the following databases: Literatura Latino-Americana e do Caribe em Ciências de Saúde, Sciverse Scopus, Web of Science, Cumulative Index to Nursing and Allied Health Literature, Cochrane Central Register of Controlled Trials, including thirteen studies. Results: the evidence showed that the dose of heparin (300 IU/ml) is the most used in maintaining the patency of the totally implanted central venous catheter. Conclusion: according to the selected studies, the lowest dose of heparin found in maintaining the patency of the totally implanted central venous catheter in cancer patients was 10 UN/ml with a volume of 5 ml of the heparin solution.


2020 ◽  
Vol 9 (12) ◽  
pp. e43291210459
Author(s):  
Wanessa Kallyne Nascimento ◽  
Maria Eduarda Bezerra Sales Queiroz ◽  
Larissa Pereira Costa ◽  
Eliane Araújo de Oliveira ◽  
Bernadino Fernández-Calvo ◽  
...  

O objetivo do presente estudo foi avaliar os efeitos da Estimulação Transcraniana por Corrente Contínua (ETCC) sob a cognição, funcionalidade e os sintomas comportamentais e psicológicos em indivíduos com Doença de Alzheimer (DA). Trata-se de uma revisão sistemática, realizada nas bases Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE (PubMed), Cumulative Index to Nursing and Allied Health Literature (CINAHL), PsycINFO, Scopus, Web of Science, Lilacs e Embase. O período de publicação do material utilizado na presente revisão levou em consideração estudos publicados desde sua inserção até setembro de 2020. Como resultados, foram encontrados 759 estudos, dos quais 742 foram removidos de acordo com os critérios de elegibilidade. Foram eleitos 17 artigos para a leitura completa, dos quais 7 foram rejeitados por não preencherem os critérios de elegibilidade. Portanto, 10 estudos foram selecionados e incluídos para análise nesta revisão.  As evidências atuais sugerem que a ETCC se configura como terapia alternativa para pacientes com DA. Contudo, a recomendação desta terapêutica deve ser realizada com cautela, uma vez que os achados encontrados no presente trabalho indicam baixa qualidade dos estudos atuais, acompanhados de dados utilizando pequenos tamanhos de amostra e problemas metodológicos, o que sugere que mais estudos são necessários para verificar a eficácia clínica da ETCC nesta população.


2021 ◽  
Author(s):  
Johan Wormser ◽  
Christophe Romanet ◽  
François Philippart ◽  
Aurel Bellaïche

Abstract Background: Patients admitted in intensive care units often receive mechanical ventilation. Prior to extubation, the weaning process could be a major cause of dyspnea and anxiety in awake intubated patients. Hypnotherapy is nowadays commonly used to manage anxiety and pain. Our hypothesis is that hypnosis would decrease stress during the weaning and extubation process.Methods: This systematic review follows PRISMA Guidelines and was registered in PROSPERO (CRD42020171445). Web of Science, MEDLINE and Cochrane Central Register of Controlled Trials databases were searched between 02/23/20 and 03/11/20. We included all types of interventional trials assessing hypnotherapy for intubated patients whom were undergoing the weaning process or extubation. Two of the authors independently screened studies, extracted data and assessed risk of bias from identified trials.Results: One study fulfilled our selection. This case series included 2 patients. Eleven sessions were completed. Hypnotherapy decreased anxiety during the weaning process from a median of 1 point (Interquartile Range: 1.0-2.5). Increase in oxygen saturation is also reported. There was no evidence of neither an anxiety reduction or an oxygen saturation improvement. This is due to the scarcity of publication and the methodological design of the one selected study.Conclusions: We cannot conclude whether or not hypnosis could be recommended in the weaning process of intubated patients. Further studies are needed to assess hypnosis effects.


2021 ◽  
Author(s):  
Afshin Heidari ◽  
◽  
Saeed Biroudian ◽  
Hadi Zamanian

Review question / Objective: This study aims to distinguish disparities in usage and telemedicine access in the era of CoVid-19 from diverse perspectives. Condition being studied: Telemedicine is the distribution and delivery of health services through remote telecommunications. Since the beginning of the CoVid-19 Pandemic, the application of telemedicine services has been grown; and by increasing the usage of telemedicine, the access gaps of telemedicine are multiplied. The disparities of telemedicine access and use are being reviewed and discussed in this review. Information sources: Pubmed, Embase (via Ovid), Psychinfo (via Ovid), WHO Global Index Medicus, Global Health (via Ovid), Cochrane CENTRAL Register of Controlled Trials, Web of Science, SCOPUS, and CINAHL(EBSCO).


QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Hanna Habib Hanna ◽  
Sherif Abdelhalim ◽  
Aboelatta Khairy ◽  
Rihaj Mohammed Abdulfattah Al-Abbasi

Abstract Background ERAS programs are not only used in abdominal surgeries, they are also used in cardiothoracic, gynecology, urology, orthopedic, and neurosurgery. Many authors and surgeons worldwide have been adapting this program, also trying to modify it due to its promising outcomes and it’s low damage toit’s continence. Objective To present an updated assessment of perioperative care in colorectal surgery from the available evidence and Enhanced Recovery After Surgery (ERAS) group recommendations. Patients and Methods We performed this systematic review and meta-analysis in accordance to the recommendations of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement and Meta-analysis Of Observational Studies in Epidemiology (MOOSE) statement. PRISMA and MOOSE are reporting checklists for Authors, Editors, and Reviewers of Meta-analyses of interventional and observational studies. According to International committee of medical journal association (ICJME), reviewers must report their findings according to each of the items listed in those checklists. An electronic search was conducted from the inception till March 2019 in the following bibliographic databases: Medline via PubMed, SCOPUS, Cochrane Central Register of Controlled Trials (CENTRAL), Web of Science, and Google Scholar to identify relevant articles. We used different combinations of the following queries: ("Colorectal Surgery"[Mesh]) AND ("Enhanced recovery" OR "conventional care"). The search have been done with no limit regarding the year publication or language. Results In the present study, we searched Medline via PubMed, SCOPUS, Web of Science, Cochrane Central Register of Controlled Trials (CENTRAL), and Google Scholar from their inception till March 2019. The search retrieved 2861 unique records. We then retained 41 potentially eligible records for full-texts screening. Finally, 28 reports of 25 RCTs were included in the present systematic review and meta-analysis Conclusion ERAS was proven to be feasible, minimally invasive, cheap, relatively easy, which is safe and effective at the same time. This program can be ideal for patients undergoing elective colo-rectal surgery, yet more studies should be conducted in Egypt to compare results regarding different approaches of this program with longer follow up and randomization of patients.


2021 ◽  
pp. 175857322110190
Author(s):  
Morissa F Livett ◽  
Deborah Williams ◽  
Hayley Potter ◽  
Melinda Cairns

Background Glenohumeral joint instability is associated with structural deficits and/or alterations in sensory and motor processing; however, a proportion of patients with glenohumeral joint instability fail to respond to surgical and rehabilitative measures. This systematic review aimed to establish if functional cortical changes occur in patients with glenohumeral joint instability. Methods AMED, CINAHL, Cochrane Central Register of Controlled Trials, Embase, Medline, PEDro, Pubmed, PsychINFO and Scopus were searched from inception to 17 March 2021. Randomised controlled trials and non-randomised trials were included and quality was appraised using the Downs and Black tool. Results One thousand two hundred seventy-nine records were identified of which five were included in the review. All studies showed altered cortical function when comparing instability patients with healthy controls and included areas associated with higher cortical functions. Discussion The findings of this systematic review offer some insight as to why interventions addressing peripheral pathoanatomical factors in patients with glenohumeral joint instability may fail in some cases due to functional cortical changes. However, data are of moderate to high risk of bias. Further high-quality research is required to ascertain the degree of functional cortical changes associated with the type and duration of glenohumeral joint instability.


Metabolites ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 375
Author(s):  
John Koussiouris ◽  
Nikita Looby ◽  
Melanie Anderson ◽  
Vathany Kulasingam ◽  
Vinod Chandran

Metabolomics investigates a broad range of small molecules, allowing researchers to understand disease-related changes downstream of the genome and proteome in response to external environmental stimuli. It is an emerging technology that holds promise in identifying biomarkers and informing the practice of precision medicine. In this review, we summarize the studies that have examined endogenous metabolites in patients with psoriasis and/or psoriatic arthritis using nuclear magnetic resonance (NMR) or mass spectrometry (MS) and were published through 26 January 2021. A standardized protocol was used for extracting data from full-text articles identified by searching OVID Medline ALL, OVID Embase, OVID Cochrane Central Register of Controlled Trials and BIOSIS Citation Index in Web of Science. Thirty-two studies were identified, investigating various sample matrices and employing a wide variety of methods for each step of the metabolomics workflow. The vast majority of studies identified metabolites, mostly amino acids and lipids that may be associated with psoriasis diagnosis and activity. Further exploration is needed to identify and validate metabolomic biomarkers that can accurately and reliably predict which psoriasis patients will develop psoriatic arthritis, differentiate psoriatic arthritis patients from patients with other inflammatory arthritides and measure psoriatic arthritis activity.


2016 ◽  
pp. 33-42
Author(s):  
Débora Wanderley ◽  
Joaquim José de Souza Costa Neto ◽  
Marcelo Moraes Valença ◽  
Daniella Araújo de Oliveira

A intolerância aos movimentos, incapacidade do pescoço e alterações nos músculos pericranianos são aspectos que podem interferir durante as crises de migrânea. A presença destes achados tornou a fisioterapia uma modalidade terapêutica alternativa para as cefaleias. Assim, as desordens estruturais e comportamentais musculares podem promover modificações na biomecânica da cabeça e região cervical, bem como limitações na mobilidade cervical no paciente com cefaleia, as quais podem ser tratadas por meio de diferentes modalidades fisioterapêuticas. O objetivo deste estudo foi revisar as publicações mais relevantes sobre o papel da fisioterapia no tratamento das cefaleias, a fim de fundamentar e direcionar o tratamento não farmacológico destes pacientes. Foi feito um levantamento da literatura, entre setembro/2015 e maio/2016, nas bases de dados MEDLINE/ PubMed, LILACS e Cochrane Central Register of Controlled Trials - CENTRAL, buscando ensaios clínicos randomizados e quasi randomizados sobre o tema. Os descritores do MeSH/DeCS utilizados foram: 'cefaleia', 'modalidades de fisioterapia', e seus equivalentes em inglês. Foram identificados 589 artigos, dos quais 19 foram incluídos, segundo os critérios de elegibilidade. De acordo com os resultados dos estudos avaliados, a fisioterapia promove melhora da cefaleia, dos sintomas associados e das disfunções musculoesqueléticas relacionadas. Entre as modalidades utilizadas estão correção postural, mobilização da coluna, alongamento muscular, técnicas de relaxamento, massagem, exercícios ativos ou passivos, entre outras. Devido à baixa qualidade metodológica da maioria dos estudos, são necessários novos ensaios controlados e randomizados, baseados nos critérios diagnósticos da ICHD, utilizando protocolos descritos de maneira mais detalhada e reprodutível, incluindo a avaliação de efeitos adversos.


Sign in / Sign up

Export Citation Format

Share Document