scholarly journals Lupus mastitis in men

2021 ◽  
Vol 10 (7) ◽  
pp. e2210716182
Author(s):  
André Luiz Costa e Silva ◽  
Diego Maia Diógenes Rabelo Caldas ◽  
Laura Cristina Costa e Silva ◽  
Alyne Barreto Mesquita de Goés ◽  
Thais Cristina Loyola da Silva ◽  
...  
Keyword(s):  
Lupus Erythematosus ◽  
Web Of Science ◽  
Clinical Presentation ◽  
Academic Community ◽  
Malignant Neoplasms ◽  
Initial Manifestation ◽  
Skin Changes ◽  
Lymphoplasmacytic Infiltrate ◽  
Breast Cancer In Men ◽  
Selection Of

To analyze the pathophysiological aspects of lupus mastitis (LM), clinical presentation, epidemiology, radiological and histological findings, and treatment, to disseminate it to the academic community and draw attention to this pathology as one of the differential diagnoses in the management of breast lesions in males, especially in the case of breast cancer in men. A literature review was done by searching scientific studies in the PubMed / Medline, Scopus, Scielo, Embase, Web of Science, and Google Scholar databases. Relevant scientifically validated studies related to lupus mastitis in men were selected. The analysis, review and selection of articles carried out in pairs, blindly and separately, based on the reading of the title and abstract, with a third reviewer in case of disagreement.  The LM should be suspect in patients known to have lupus erythematosus who present painful breast nodules associated with skin changes. However, LM can be the initial manifestation of lupus and mimic, both clinically and imaging, malignant neoplasms. The histopathological diagnostic criteria are well-established, finding mainly hyaline fat necrosis and lymphoplasmacytic infiltrate. Treatment must be drug-based as invasive procedures can exacerbate the injury. Due to physiological and anatomical aspects, this condition can appear and evolve differently in men. The knowledge of this pathology is necessary to carry out the correct approach since the non-identification of the disease and its erroneous management can lead to complications and irreversible sequelae to the patient.

Viral arthritis

2013 ◽  
Author(s):  
Stanley J. Naides
Keyword(s):  
Lupus Erythematosus ◽  
Host Response ◽  
Clinical Presentation ◽  
Viral Infections ◽  
Acute Infection ◽  
Sudden Onset ◽  
Joint Involvement ◽  
Host Interactions ◽  
Symptoms And Signs ◽  
Selection Of

Viral infection may cause sudden onset polyarthralgia or polyarthritis. Recognizing viral syndromes during the acute phase of illness is critical as markers of acute infection may fade during convalescence. While joint symptoms and signs in many cases are self limited, in others joint involvement may persist for months to years. Acute and chronic findings may resemble classic idiopathic diseases such as rheumatoid arthritis or systemic lupus erythematosus. Some viral infections may manifest with rash, vasculitis, or organ involvement. Understanding of epidemiology, geography, clinical presentation, virus behaviour and host response assists diagnosis and selection of appropriate management. Understanding virus-host interactions may offer insights into mechanisms of pathogenesis in idiopathic rheumatic diseases.

PILONIDAL DISEASE: CHANGES IN UNDERSTANDING OF ETIOLOGY, PATHOGENESIS AND APPROACH TO TREATMENT

2019 ◽  
Vol 72 (8) ◽  
pp. 1559-1565
Author(s):  
Viktor Konoplitskyi ◽  
Ruslan Shavliuk ◽  
Dmytro Dmytriiev ◽  
Kostiantyn Dmytriiev ◽  
Oleksii Kyrychenko ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Pilonidal Sinus ◽  
Randomized Clinical Trials ◽  
Web Of Science ◽  
Surgical Intervention ◽  
Pilonidal Disease ◽  
Treatment Methods ◽  
Principles Of Treatment ◽  
Selection Of

Data from Web of Science, SCOPUS, Pub Med, Medline, E-library, and other sources was used in writing this article. The main focus was directed towards literature written in English. The selection of literature was based on such concepts as: etiopathogenesis, historical principles of treatment, methods of surgical and non-surgical intervention. Data from metanalysis publications and randomized clinical trials pertaining to the treatment of the pilonidal sinus at various stages of its formation was used, as well.

Myocardial Infarction in Systemic Lupus Erythematosus – the Sex Specific Risk Profile

2020 ◽  
Vol 26 ◽  
Author(s):  
Marija Vavlukis ◽  
Daniela Pop-Gjorceva ◽  
Lidija Poposka ◽  
Emilija Sandevska ◽  
Sasko Kedev
Keyword(s):  
Myocardial Infarction ◽  
Systemic Lupus Erythematosus ◽  
Cardiovascular Risk ◽  
Coronary Artery ◽  
Young Women ◽  
Lupus Erythematosus ◽  
Molecular Mechanisms ◽  
Clinical Presentation ◽  
Systemic Lupus ◽  
Antiinflammatory Therapy

Background: Accelerated atherosclerosis is widely present in patients with systemic lupus erythematosus. Objective: The aim of this review is to analyze the relationship between systemic lupus erythematosus and cardiovascular diseases, with the emphasis on acute myocardial infarction. Results: Various molecular mechanisms triggered by infection/inflammation are responsible for endothelial dysfunction and development of atherosclerosis at an earlier age. Contributing factor is the cumulative effect of traditional cardiovascular risk factors interaction with disease related characteristics. Myocardial infarction rates are 2- to 10-fold higher compared to the general population. Young women have the highest relative risk, however, men carry at least 3- fold higher risk than women. Coronary involvement varies from normal coronary artery with thrombosis, coronary microartery vasculitis, coronary arteritis, and coronary atherosclerosis. Typical clinical presentation is observed in men and older women, while atypical is more frequent in young women. Treatment is guided by the underlying mechanism, engaging invasive procedures alone, or accompanied with immunosuppressive and/or antiinflammatory therapy. There are significant gender differences in pathophysiology and clinical presentation. However, they receive the same therapeutic treatments. Conclusion: Systemic lupus erythematosus is a major contributor to atherosclerotic and non-atherosclerotic mechanisms involved in the development of myocardial infarction, which should be taken into account during therapeutic treatment. Although Systemic lupus erythematosus per se is a “female” disease, males are at increased cardiovascular risk and worse outcome. Method: We conducted a literature review through PubMed and Cochrane, using key words: SLE, atherosclerosis, atherothrombosis, coronary artery disease, myocardial infarction, prognosis, sex specifics.

Acute pericardial tamponade: The initial manifestation of systemic lupus erythematosus with Graves’ hyperthyroidism

Lupus ◽  
2021 ◽  
pp. 096120332110047
Author(s):  
Muming Yu ◽  
Yulei Gao ◽  
Heng Jin ◽  
Songtao Shou
Keyword(s):  
Myocardial Infarction ◽  
Systemic Lupus Erythematosus ◽  
Female Patient ◽  
Lupus Erythematosus ◽  
Pericardial Tamponade ◽  
Medical Emergency ◽  
Systemic Lupus ◽  
Initial Manifestation ◽  
Life Threatening ◽  
Obstructive Shock

Acute pericardial tamponade, which can cause obstructive shock, is a serious life-threatening medical emergency that can be readily reversed by timely identification and appropriate intervention. Acute pericardial tamponade can occur for a number of reasons, including idiopathic, malignancy, uremia, iatrogenic, post-myocardial infarction, infection, collagen vascular, hypothyroidism, and others. Systemic lupus erythematosus (SLE) and hyperthyroidism associated with pericardial tamponade are rarely reported. Here, we report the case of a 20-year-old female patient was final diagnosed of SLE with Graves’ hyperthyroidism.

Hemophagocytic Syndrome as the Initial Manifestation of Systemic Lupus Erythematosus

2014 ◽  
Vol 10 (5) ◽  
pp. 321-324 ◽  
Author(s):  
César Antonio Egües Dubuc ◽  
Miren Uriarte Ecenarro ◽  
Carlos Meneses Villalba ◽  
Vicente Aldasoro Cáceres ◽  
Iñaki Hernando Rubio ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Hemophagocytic Syndrome ◽  
Systemic Lupus ◽  
Initial Manifestation

scholarly journals HOMOLOGOUS DISEASE IN THE ADULT RAT, A MODEL FOR AUTOIMMUNE DISEASE

1963 ◽  
Vol 118 (4) ◽  
pp. 635-648 ◽  
Author(s):  
Peter Stastny ◽  
Vernie A. Stembridge ◽  
Morris Ziff
Keyword(s):  
Autoimmune Disease ◽  
Lupus Erythematosus ◽  
Connective Tissue Diseases ◽  
Skin Lesions ◽  
Cutaneous Lesions ◽  
Adult Rats ◽  
Hydropic Degeneration ◽  
Skin Changes ◽  
Adult Rat ◽  
The One

The cutaneous lesions of adult rats with homologous disease are described, and evidence is presented to indicate that they have an immunologic basis. The skin changes included erythema, purpura, edema, and a variety of inflammatory lesions. In the more active lesions, dermal infiltration, hydropic degeneration, acanthosis, and atrophy of the epidermis with hyperkeratosis and follicular plugging were present. In some cases, ulceration and sloughing were also observed. More chronic lesions were characterized by atrophy of the epidermis and collagenization of the dermis with disappearance of the skin appendages. Rejection of autografts was observed simultaneously with acceptance of homografts. The histologic appearance of autografts undergoing rejection was similar to that of the spontaneous skin lesions, suggesting that the latter, too, had an immunologic basis. In favor of this, also, was the specificity of the dermatitis for the skin of the host, with sparing of neighboring homograft tissue. There was a histologic similarity between the spontaneous skin lesions of homologous disease and those of lupus erythematosus on the one hand, and scleroderma on the other, thus supporting the possibility that the cutaneous lesions of these connective tissue diseases of man may also have an immunologic basis. It was concluded that the adult rat with homologous disease may furnish a model for human autoimmune disease.

Poster 327: Acute Paralysis as the Initial Manifestation of Systemic Lupus Erythematosus: A Case Report

PM&R ◽  
2009 ◽  
Vol 1 ◽  
pp. S246-S246
Author(s):  
Jasmine Martinez-Barrizonte ◽  
Kresimir Banovac ◽  
Alberto Martinez-Arizala
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Case Report ◽  
Lupus Erythematosus ◽  
Systemic Lupus ◽  
Initial Manifestation

Chorea as an Initial Manifestation of Systemic Lupus Erythematosus

1984 ◽  
Vol 23 (5) ◽  
pp. 298-300 ◽  
Author(s):  
Osamu Arisaka ◽  
Kaoru Obinata ◽  
Hidekuni Sasaki ◽  
Madoka Arisaka ◽  
Kenichiro Kaneko
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Systemic Lupus ◽  
Initial Manifestation

scholarly journals NEW MATERIALS FROM THE AMHERST MEREZHKOVSKY ARCHIVE 2. N. A. BERDIAEV IN THE «DIARIES» OF T. N. GIPPIUS (1906–1908)

2021 ◽  
Vol 2 ◽  
pp. 144-172
Author(s):  
Margarita Mikhailovna Pavlova ◽  
Keyword(s):  
Academic Community ◽  
New Materials ◽  
Russian Culture ◽  
The Relationship ◽  
Selection Of

This publication introduces the academic community to the new data from the archives of the Merezhkovskys and D. V. Filosofov, which are stored in the Amherst Center for Russian Culture (Massachusetts, USA). It presents a selection of letters by Filosofov (1906) and N. A. Berdiaev (1907) that provide new details concerning the relationship between the two. Excerpts from the «diaries» of T. N. Gippius that supplement the «Berdiaev» narrative are published as an appendix.

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