scholarly journals Letter to the Editor: Effectiveness of the Varicella Vaccine Among Korean Children: Suggestions for Future Research

2022 ◽  
Vol 37 (1) ◽  
Author(s):  
BongKyoo Choi ◽  
Hyunjeong Cho ◽  
Younchul Shin ◽  
Eun-Kyoung Lee
Vaccines ◽  
2021 ◽  
Vol 9 (5) ◽  
pp. 492
Author(s):  
Yunhwa Kim ◽  
Ji-Young Hwang ◽  
Kyung-Min Lee ◽  
Eunsil Lee ◽  
Hosun Park

The prevalence of varicella is especially high among children in the age group of 4–6 years in South Korea, regardless of vaccination. We investigated the immune status of healthy children enrolled in day-care centers and compared pre- and post-vaccination immunity. Antibody titers were measured using a glycoprotein enzyme-linked immunosorbent assay (gpEIA) kit, and the seroconversion rate was assessed using a fluorescent antibody to membrane antigen (FAMA) test. Among 541 vaccinated children, 109 (20.1%) had breakthrough varicella. However, 13 (72.2%) of the 18 unvaccinated children had a history of varicella. The gpEIA geometric mean titers (GMTs) of pre- and 5 weeks post-vaccination in 1-year-old children were 14.7 and 72 mIU/mL, respectively, and the FAMA seroconversion rate was 91.1%. The gpEIA GMTs of 2-, 3-, 4-, 5-, and 6-year-old children were 104.1, 133.8, 223.5, 364.1, and 353.0 mIU/mL, respectively. Even though the gpEIA GMT increased with age, the pattern of gpEIA titer distribution in 4- to 6-year-old vaccinees without varicella history represented both waning immunity and natural boosting immunity. These results suggest that some vaccinees are vulnerable to varicella infection. Therefore, it is necessary to consider a two-dose varicella vaccine regimen in South Korea.


2021 ◽  
pp. 089443932110375
Author(s):  
Il Bong Mun ◽  
Seyoung Lee

The present study investigates the mechanisms underlying the relationship between parental depression and children’s smartphone addiction. It explores the effects of parental depression on children’s smartphone addiction, as well as the mediating roles of parental neglect and children’s self-esteem in this relationship, which multiplies sequentially. We utilize data—comprising 2,396 children and their parents—from the National General Survey on Korean Children, using parent–child dyads. First, a hierarchical regression analysis shows that parental depression significantly and positively predicts children’s smartphone addiction ( B = .29, SE = .03, p < .001). Second, Hayes’s PROCESS macro (Model 6), executed to test the mediation effects, reveals that the effect of parental depression on children’s smartphone addiction is significantly mediated by parental neglect ( B = .07, Boot SE = .01, 95% Boot CI [.05, .10]) and children’s self-esteem ( B = .12, Boot SE = .01, 95% Boot CI [.10, .14]). Moreover, the serial mediation model’s results support that parental neglect and children’s self-esteem serially mediate the relationship between parental depression and children’s smartphone addiction ( B = .02, Boot SE = .004, 95% Boot CI [.01, .03]), implying that a higher level of parental depression is sequentially associated with increased parental neglect that reduces children’s self-esteem and consequently accelerates their smartphone dependence. The theoretical and practical implications of the results as well as the directions for future research are discussed.


2016 ◽  
Vol 34 (11) ◽  
pp. 2203-2226 ◽  
Author(s):  
Jingu Kim ◽  
Eunha Kim

The primary aim of this study was to examine the direct and indirect links of rejecting/neglecting parenting, sibling victimization, and friendship quality with peer victimization using a convenience sample of 584 Korean children in Grades 3 to 6. In addition, we tested whether these associations differed between male and female students. Structural equation modeling was performed to analyze the data. The results revealed rejecting/neglecting parenting indirectly influenced peer victimization through sibling victimization for both males and females, although such effects were stronger for females than males. Sibling victimization had a direct effect on peer victimization across both sexes, although it indirectly influenced peer victimization through poor friendship quality only for males. Therefore, bullying prevention and intervention programs must involve parents to make them aware of the important role they play in this process and to improve their parenting styles and involvement in sibling conflicts. Furthermore, while the role of friendship quality needs to be highlighted to prevent peer victimization among males, future research continues to explore other peer variables that are related to decreased peer victimization for females.


2020 ◽  
Vol 35 (28) ◽  
Author(s):  
BongKyoo Choi ◽  
Ji-hyeun Shin ◽  
Jee Eun Lee ◽  
Sangbaek Ko

2021 ◽  
Vol 36 (27) ◽  
Author(s):  
BongKyoo Choi ◽  
Ji-hyeun Shin ◽  
Jee Eun Lee ◽  
Sangbaek Koh

2004 ◽  
Vol 28 (3) ◽  
pp. 128-128
Author(s):  
David C. Clarke

The following is the abstract of the article discussed in the subsequent letter: Silverthorn DU. Restoring physiology to the undergraduate biology curriculum: a call to action. Adv Physiol Educ 27:91–96, 2003.—The National Research Council-sponsored report, BIO 2010: Transforming Undergraduate Education for Future Research Biologists, describes a number of significant changes that should be made to the undergraduate biology curriculum if we are to adequately train students to become the researchers of the 21st century. What should be of concern to the physiology community is the lack of identifiable physiology in the proposed revisions. This article describes the report and suggests some steps that physiologists can take to enhance our discipline in the undergraduate biology curriculum.


2014 ◽  
Vol 3 (1) ◽  
pp. 91 ◽  
Author(s):  
Sung-Ho Cha ◽  
Seon-Hee Shin ◽  
Taek-jin Lee ◽  
Chang Hwi Kim ◽  
Michael Povey ◽  
...  

PEDIATRICS ◽  
1996 ◽  
Vol 97 (6) ◽  
pp. 932-932
Author(s):  
Steve Kohl

Dr May's letter raises the important question of the use of varicella vaccine in households with high-risk hosts such as neonates of varicella-susceptible mothers, varicella-susceptible pregnant women, HIV-positive individuals, or individuals receiving immunosuppressive therapy. The manufacturer warns that vaccine recipients avoid such hosts. On the basis of low to absent levels of transmission of vaccine from healthy recipients to others, the Committee on Infectious Diseases feels this is a very unlikely occurrence. In the Weibel study, using a vaccine with ten times the current vaccine viral load, there were no symptomatic transmissions to unvaccinated siblings, and only 3/439 seroconversions attributed to vaccine transmission (although these actually may have been attributed to wild virus).1


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