scholarly journals To study the Clinico epidemiological profile of pityriasis rosea in a tertiary care Hospital in North Kerala

Author(s):  
Dr. Shwetha V Rajiv
Author(s):  
Balaji Ommurugan ◽  
Amita Priya ◽  
Swaminathan Tambaram Natesh

ABSTRACTPityriasis Rosea is a self-limiting skin disorder of unknown etiology affecting women more than men. It is very rare in pregnancy and evidence shows conflicting reports on pregnancy outcomes related to Pityriasis Rosea. But however recent evidence says, pregnancy outcomes are not altered, although clinicians must monitor the patient throughout the gestation for adverse outcomes. Hence, we report a case of Pityriasis Rosea infection in a primigravida, in the first trimester and the follow up done in a tertiary care hospital in Southern India.KEYWORDSRASH, FIRST TRIMESTER, ANOMALY SCAN, HUMAN HERPES VIRUS


Author(s):  
Geeta Yadav ◽  
Geeta Pardeshi ◽  
Neelam Roy

Background: Malaria is an important public health problem in India. Severe and complicated forms of malaria are usually associated with Plasmodium falciparum species. But recently published literature suggests that Plasmodium vivax infection also presents as severe malaria. The objective was to study clinical and epidemiological profile of patients with P. vivax malaria admitted in Safdarjung hospital.Methods: A record based retrospective study was conducted in Vardhman Mahavir Medical College & Safdarjung Hospital, a tertiary care hospital in Delhi. Data were collected from all case records with ICD 10 codes for Malaria (B50-B54) for the year 2011 obtained from Medical Records Department, Safdarjung Hospital and analyzed using SPSS 21.0.Results: A total of 147 case records which had information about the test results for type of malaria infection were reviewed. Out of 147, 89 (60.5%) had P. vivax malaria. Of the 89 patients with P. vivax malaria, 47 (53%) were children and 63 (70.7%) were males. A peak in the number of inpatients was seen in September with median duration of hospital stay of 4 days and case fatality rate of 9%. A total of 56 (63%) patients had one or more severe manifestations of malaria as per WHO criteria. The most common severe manifestation was bleeding 27 (30%) followed by impaired consciousness 18 (20%).Conclusions: In more than half of the malaria patients admitted at the tertiary care centre the diagnosis was P. vivax malaria. Of them 63% patients had severe malaria as per WHO criteria.


Author(s):  
Rangaraj Murugaiyan ◽  
Karthikeyan Kaliyaperumal ◽  
Balamurugan Rangasamy

<p class="abstract"><strong>Background:</strong> Human herpes virus (HHV) 6 and 7 belongs to <em>Betaherpesviridae</em> a sub-family of <em>Herpesviridae</em>. HHV-6 and HHV-7 are double stranded DNA group viruses. The cause of PR and the disease caused by HHV is not well established. The association of HHV 6 and HHV 7 with pityriasis rosea (PR) is under controversy. The HHV DNA is also detected in normal controls which evidence the non- significance of HHV in the pathogenesis of PR.</p><p class="abstract"><strong>Methods:</strong> The study design was planned for 35 consecutive cases of pityriasis rosea of all age groups. This study was carried out at the department of Dermatology and Central Research Lab, at Sri Manakula Vinayagar Medical College and Hospital, a tertiary care hospital in Puducherry. Since there is no universally accepted diagnostic protocol for PR, we have planned to detect HHV-6 and 7 DNA by PCR from the lesions of all clinically diagnosed cases of pityriasis rosea.<strong></strong></p><p class="abstract"><strong>Results:</strong> In contrary to the expected outcome that HHV-6 and HHV-7 positivity would correlate to the possible pathogenesis of the disease, the PCR results of all the 35 samples from clinically suspected PR cases were found to be negative.</p><p class="abstract"><strong>Conclusions:</strong> We conclude that HHV-6 and HHV-7 viruses may not always play a role in the pathogenesis of the disease. Thus PR speculated to have more than one etiology may have agents other than HHV6 and HHV7 involved in the pathogenesis of the disease.</p>


2019 ◽  
Vol 8 (8) ◽  
pp. 527-531
Author(s):  
Ajay Kumar G ◽  
Sailaja Rani M ◽  
Sree Gowthami I ◽  
Balachandrudu B ◽  
Dhanyasree S ◽  
...  

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