scholarly journals Clinico-epidemiological profile of patients admitted with Plasmodium vivax malaria in a tertiary care hospital, Delhi

Author(s):  
Geeta Yadav ◽  
Geeta Pardeshi ◽  
Neelam Roy

Background: Malaria is an important public health problem in India. Severe and complicated forms of malaria are usually associated with Plasmodium falciparum species. But recently published literature suggests that Plasmodium vivax infection also presents as severe malaria. The objective was to study clinical and epidemiological profile of patients with P. vivax malaria admitted in Safdarjung hospital.Methods: A record based retrospective study was conducted in Vardhman Mahavir Medical College & Safdarjung Hospital, a tertiary care hospital in Delhi. Data were collected from all case records with ICD 10 codes for Malaria (B50-B54) for the year 2011 obtained from Medical Records Department, Safdarjung Hospital and analyzed using SPSS 21.0.Results: A total of 147 case records which had information about the test results for type of malaria infection were reviewed. Out of 147, 89 (60.5%) had P. vivax malaria. Of the 89 patients with P. vivax malaria, 47 (53%) were children and 63 (70.7%) were males. A peak in the number of inpatients was seen in September with median duration of hospital stay of 4 days and case fatality rate of 9%. A total of 56 (63%) patients had one or more severe manifestations of malaria as per WHO criteria. The most common severe manifestation was bleeding 27 (30%) followed by impaired consciousness 18 (20%).Conclusions: In more than half of the malaria patients admitted at the tertiary care centre the diagnosis was P. vivax malaria. Of them 63% patients had severe malaria as per WHO criteria.

Author(s):  
Prachi D Sondankar ◽  
Shubhangi U Agawane ◽  
Abhay B Mane ◽  
Parvinder S Chawla

Introduction: The COVID-19 caused by Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2), has spread throughout the world from its place of origin in Wuhan city of China. From origin in December 2019 till May 2021, this disease affected 222 countries in the world with 152,534,452 confirmed cases. As on May 2021, India is the second worst affected country in the world. Aim: To know the epidemiological profile and clinical outcome of COVID-19 positive patients to help in understanding the disease dynamics. Materials and Methods: It was a cross-sectional, record based study at a tertiary care hospital. All the COVID-19 laboratory confirmed positive patients admitted from 15th June, 2020 to 15th September, 2020 were included in the study. Sample size was 1146. All the required data regarding patients were collected and analysed subsequently with the help of percentages, Z-test for proportion, Chi-square test and Odds ratio. Results: The mean age of the patients was 47.06 ±17.4 years ranging from 1 to 92 years. Males were significantly higher in numbers than females. 30.19% patients had some or other co-morbidities. 89.8% patients were discharged and 9.2% patients died. More number of deaths occurred in higher age group and highest death rate was seen in the patients who had multiple co-morbidities. Conclusion: The study concludes that most of the COVID-19 patients were middle aged and males were significantly more affected than females. Most of the patients were asymptomatic at the time of admission. It can be concluded that maximum patients had favourable clinical outcome as around 90% patients being discharged and case fatality rate was 9.2%. High rate of mortality was significantly associated with higher age and presence of co-morbidities.


2017 ◽  
Vol 4 (5) ◽  
pp. 1781
Author(s):  
Venkata Krishna Munagala ◽  
Ramisetty M. UmaMahesh ◽  
Kandati Jithendra ◽  
Muni Lakshmi Ponugoti ◽  
Mohan Rao Nandam

Background: Malaria caused by Plasmodium species and transmitted by Female anopheles mosquito, still remains as a major public health concern around the world. India is one of the major contributors of malaria cases in South East Asia. Malaria accounts for 205,000 deaths with 55,000 deaths occurring in early childhood. In endemic areas, children under 5 years are particularly susceptible to infection, illness and death. The present study was aimed to study the clinical, epidemiological profile of malaria cases among children (<12 years) attending a tertiary care hospital. We also assessed the complications associated with non-severe and severe malaria. Methods: The study was conducted at a tertiary care hospital for a period of two years and all children <12 years of age diagnosed with malaria were enrolled in the study. The demographic, clinical and laboratory parameters were observed and noted. Cases were categorized into severe and non-severe malaria based on the WHO guidelines.Results: A total of 2420 cases were observed and 250 cases of malaria were diagnosed, of which 136 were p. vivax mono infections, 82 falciparum malaria and 32 had evidence of mixed infections. Males were predominant in the study (58.8%) and 1-5 years was the common age group. Fever was the most common symptom (100%) in all cases and pallor, edema was common in falciparum malaria. jaundice was observed in 62% of mixed infections and altered sensorium in 43% of mixed infections. Severe malaria was observed almost equally in vivax and falciparum cases. Hyperparasitemia, cerebral malaria was common in falciparum cases than vivax. Thrombocytopenia, hypoglycemia and impaired consciousness were more common in mixed infections than falciparum and vivax cases.Conclusions: Present study finally concludes that there is a significant change in the trends of vivax malaria in this region where both species coexist. The spectrum of complications seen in vivax and falciparum follow a similar pattern, then mentioned earlier that complications are less frequently seen in vivax than falciparum malaria. Hence more number of studies is required to generate the differing patterns associated with vivax and compare them with different studies from geographic regions. 


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