Assessment of the functional state of the cardiovascular system in workers of the government military mine-rescue (emergency rescue) services by the monitoring method of arterial pressure and heart rate

The article presents the results of a clinical and instrumental examination of 80 healthy women (average age 32,313,57 years) in order to assess the heart rhythm disturbances after induction of superovulation duringin vitrofertilization. All women were examined twice before and after induction of superovulation during extracorporeal fertilization. Clinical and instrumental examination included: electrocardiography at rest; echocardiography; 24-hour ECG monitoring with heart rate variability analysis; 24-hour blood pressure monitoring. Induction of superovulation is associated with a significant increase in mean daily HR max (р0,01), and consequently with an increase in myocardial oxygen demand. It has been established that induction of superovulation contributes to the development of supraventricular arrhythmias (р0,01) and an increase in episodes of apnea/hypnea (р0,01). Regression analysis revealed predictors of supraventricular arrhythmias after induction of superovulation, including adverse circadian heart rate profile, adverse circadian blood pressure profile, impaired autonomic regulation of heart activity (р0,01). It was shown that the appearance of rhythm disturbances is associated with both the initial functional state of the cardiovascular system and its response to the induction of superovulation. It was established a correlation between the estradiol concentration and the increase of daily average heart rate after induction of superovulation (r=0,30,р0,05), apnea/hypnea index after induction of superovulation (r=0,34,р0,05). Conclusion. Superovulation induction may exacerbate existing chronic cardiovascular diseases. Due to the adverse effect of superovulation induction on the daily heart rate profile, women need to evaluate the functional state of the cardiovascular system duringinvitrofertilization planning. This will prepare the woman for the upcoming procedure and avoid adverse reactions from the cardiovascular system in response to stimulation of superovulationin vitrofertilization.

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Vasodepressor responses elicited by diencephalic stimulation in dogs

American Journal of Physiology-Legacy Content ◽

10.1152/ajplegacy.1964.207.4.915 ◽

1964 ◽

Vol 207 (4) ◽

pp. 915-920 ◽

Cited By ~ 8

Author(s):

Ralph J. Gorten ◽

Orville A. Smith ◽

Robert F. Rushmer

Keyword(s):

Central Nervous System ◽

Heart Rate ◽

Arterial Pressure ◽

Cardiovascular System ◽

System Control ◽

Experimental Conditions ◽

Nervous Control ◽

Anesthetized Dogs ◽

Systemic Arteries ◽

Central Nervous System Control

Tachycardia and peripheral vasoconstriction are the usual means by which the cardiovascular system, under nervous control, attempts to compensate for a lowering of pressure in the systemic arteries. When such compensatory efforts are absent during sudden, unexpected periods of hypotension, an alteration in central nervous system control should be suspected. The possibility of producing such alterations in the control of the circulation under experimental conditions was studied in five anesthetized dogs. Diencephalic areas were found in which electrical stimulation evoked a lowering of arterial pressure in the absence of tachycardia. Electrodes were chronically implanted in these areas so that stimulation could be performed in the unanesthetized state. The observed effects on the cardiovascular system were not always the same as those induced while the animals were anesthetized. The decrease in arterial pressure was usually less in extent. Occasionally an actual rise in pressure occurred, followed after the period of stimulation by a decrease in arterial pressure and heart rate.

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FACTOR STRUCTURE OF FUNCTIONAL PARAMETERS OF WOMEN WITH POST-MASTECTOMY SYNDROME WITH DIFFERENT LEVELS OF FUNCTIONAL STATE OF THE CARDIOVASCULAR SYSTEM

Sport Science and Human Health ◽

10.28925/2664-2069.2019.1.12 ◽

2019 ◽

Author(s):

Tetiana Odinets

Keyword(s):

Breast Cancer ◽

Heart Rate ◽

Cardiovascular System ◽

Factor Structure ◽

Functional State ◽

Breast Cancer Treatment ◽

Font Size ◽

Functional Parameters ◽

Postmastectomy Syndrome ◽

Different Levels

HUMAN HEALTH Open Journal Systems ipv6 ready Journal Help User Username Password Remember me Notifications View Subscribe Language Select Language Journal Content Search Search Scope Browse By Issue By Author By Title Other Journals Categories Font Size Make font size smaller Make font size default Make font size larger Home About Login Register Search Current Archives Announcements Editorial Board Home > No 1 (2019) > Odinets FACTOR STRUCTURE OF FUNCTIONAL PARAMETERS OF WOMEN WITH POST-MASTECTOMY SYNDROME WITH DIFFERENT LEVELS OF FUNCTIONAL STATE OF THE CARDIOVASCULAR SYSTEM Tetiana Odinets Abstract Modern approaches used in breast cancer treatment resulted in increasing survival rates. However, significant adverse events such as сardiotoxicity and cardiovascular complications remain high. A lot of women experienced fatigue, arrhythmias, heart failure, ischemic heart disease, and pulmonary side effects induced by breast cancer treatment. The objective: to determine the features of the factor structure of functional parameters in women with postmastectomy syndrome with different levels of functional state of the cardiovascular system. Methods: analysis of sources of literature and empirical data; rheography, spirography, analysis of heart rate variability; anthropometry; mathematical statistics methods. Results. a developed method for estimating the level of functional state of the cardiovascular system of women with postmastectomy syndrome based on age and objective indicators of central hemodynamics: heart rate, minute blood volume and left ventricular work, as well as their significant contribution to overall predicted level. Based on the values of the determined parameters and coefficients of multiple regression, criteria of levels of functional state of the cardiovascular system of patients with postmastectomy syndrome are determined. The proposed method allows to carry out rapid monitoring and with a high degree of probability to assess the functional state of the cardiovascular system of the patients with postmastectomy syndrome, as well as to determine the effectiveness of therapeutic, rehabilitation measures and make adjustments to the program of rehabilitation. Defined factors of the direction of the rehabilitation process with the integral account of the predicted level of the functional state of the cardiovascular system are in the manuscript. It has been identified that the hemodynamic factor has covered 22.37% of the dispersion in women with the low level of functional state, 21.24% – with the lower-than-average level, 22.06 – with the average level; expiratory – 17.15%, 16.74% and 17.48; vegetative – 11.21%, 13.29% and 12.97% at corresponding levels at outpatient rehabilitation stage. Conclusions. obtained results are the basis for choosing priority means of physical rehabilitation during developing a program for the rehabilitation of women with postmastectomy syndrome with various levels of the functional state of the cardiovascular system.

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Dynamics of the functional state of the body of young athletes practicing sports games

Hygiene and Sanitation ◽

10.47470/0016-9900-2021-100-3-268-273 ◽

2021 ◽

Vol 100 (3) ◽

pp. 268-273

Author(s):

Serghei I. Cebanu ◽

Raisa D. Deleu ◽

Alisa V. Tabîrța ◽

Ovidiu I. Tafuni ◽

Grigore E. Friptuleac

Keyword(s):

Blood Pressure ◽

Arterial Pressure ◽

Cardiovascular System ◽

Functional State ◽

Peripheral Resistance ◽

Systolic Pressure ◽

The Body ◽

Motor Reaction ◽

Young Athletes ◽

Functional Changes

Introduction. Maintaining and strengthening young athletes’ health is very important since a growing body is more sensitive than an adult one. The overload on young athletes’ bodies’ functional systems is much higher compared to their peers who do not engage in intense physical activities and sports. This study aimed to assess the functional changes in the body of young athletes practicing sports games in the training process. Materials and methods. The functional state of the body of young athletes practicing five types of sports (volleyball, basketball, football, tennis, and handball) was studied on a representative group of 94 people, of which 50 (53.2%) males and 44 (46.8%) females with an average age of 17.7 ± 0.19 years. The cardiovascular system, central nervous system, respiratory system, and musculoskeletal system were investigated. The functional state assessment was carried out, taking into account the degree and direction of changes in the dynamics of training of individual indicators and integral indicators. It was determined the degree of risk of developing adverse functional changes. To identify premorbid states, we establish the type of self-regulation of blood circulation. Results. The obtained results in this study indicate that significant changes express the biological significance of the response of athletes to the conditions of training in the indices of the functions of the cardiovascular and central nervous systems and the musculoskeletal system. The indices of the functional state of the young athletes’ body at the end of the training changed in both directions. The degree of their severity fluctuated within limits from little too clearly expressed values. On the part of the cardiovascular system, an acceleration of heart rate from 60.1 ± 0.93 to 123.1 ± 0.93 beats/min (p < 0.001) was noted, an increase of systolic blood pressure from 101.1 ± 2.84 to 129.2 ± 1.40 mm Hg. (p <0.001), diastolic arterial pressure from 65.8 ± 1.60 to 76.3 ± 1.20 mm Hg. (p < 0.001), pulse pressure from 33.5 ± 2.35 to 71.5 ± 0.85 mm Hg. (p < 0.001), systolic pressure from 78.3 ± 1.75 to 84.2 ± 1.06 ml (p < 0.001), minutes volume from 4.3 ± 0.22 to 10.3 ± 0.11 l (p < 0.001), total peripheral resistance from 934.2 ± 42.11 to 1646.4 ± 37.61 dyn•s/cm5 (p < 0.001). On the part of the central nervous system, there was an increase in visual motor reaction from 236 ± 20.0 to 389 ± 5.3 ms (p < 0.001) and the auditory-motor reaction from 160 ± 3.8 to 256 ± 7.7 ms (p < 0.001). Young athletes who play volleyball have a higher load on the cardiovascular system. Functional changes are more pronounced in female athletes. The risk of developing unfavorable functional changes was noted for 15 physiological indices. The relative risk varied within 1.03-2.45 for boys and 1.04-2.90 for girls. The most pronounced risk is characteristic for total peripheral resistance (RR = 1.60), minutes volume (RR = 1.58), systolic pressure (RR = 1.55) in boys and systolic pressure (RR = 2.35), minutes volume (RR = 2.21), systolic arterial pressure (RR = 1.75), diastolic arterial pressure (RR = 1.73) and peripheral blood pressure (RR = 1.52) in girls. Conclusions. When playing sports games, a specific professional environment for different types of sports games is formed, this harming the functional state, performance, and health of young athletes.

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PROBABILITY-STATISTICAL REGULARITIES Of MILITARY MINING RESCUE SQUADS FUNCTIONING AT MINING INDUSTRY FACILITIES

Fire and Emergencies prevention elimination ◽

10.25257/fe.2021.4.66-74 ◽

2021 ◽

Vol 4 ◽

pp. 66-74

Author(s):

Beck A. ◽

Keyword(s):

Mathematical Modeling ◽

Organizational Design ◽

Mining Industry ◽

Mining Sites ◽

Emergency Rescue ◽

Rescue Services ◽

Wide Range ◽

Hazardous Production ◽

Mine Rescue ◽

Production Facilities

Purpose. The article discusses the possibility and necessity of forming and functioning of emergency rescue squads capable of carrying out a wide range of emergency rescue and other urgent operations at the mining industry facilities. Methods. The basis for theoretical researches was mathematical statistics methods, the mathematical modeling method, modeling and calculations related to the assessment of joint units forming and functioning for servicing hazardous production facilities of the mining industry. Findings. The study of statistical data on responses of the most loaded paramilitary mine rescue squads carried out on the territory of guarded hazardous production facilities of the mining industry of the Russian Federation for the period from 2015 to 2019 has been carried out. Substantiating the number of the mine rescue squads detachments for servicing calls has been carried out. The probabilistic, time and frequency characteristics of the failure-free call service have been used as criteria to substantiate the number n of the detachments. It has been found that accidents and incidents at mining sites are of a different nature, and mine rescue squads have a different load associated with the operational activity, which is explained by the industrial hazard of protected mining sites and industrial infrastructure. The main share of registered accidents at mining facilities are fires (52.4 %) and collapses (22.9 %). Research application field. The data obtained can be used in the organizational design of mine rescue units and services. Conclusions. The flow of destructive events at the mining industry facilities obeys the Poisson stationary distribution law, and the temporal characteristics of the mine rescue squads response process are described by the Erlang distribution. Methods of mathematical modeling functioning processes of urgent emergency rescue services can be used for organizational design of emergency rescue services and units at the mining industry facilities.

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The simplest device for measuring average blood pressure

Kazan medical journal ◽

10.17816/kazmj71930 ◽

1934 ◽

Vol 30 (5) ◽

pp. 404-407

Author(s):

S. M. Marcuse

Keyword(s):

Blood Pressure ◽

Arterial Pressure ◽

Cardiovascular System ◽

Functional State ◽

Pulse Wave ◽

Mean Blood Pressure ◽

A Value ◽

Average Blood Pressure ◽

The Mean ◽

Number Of Authors

The apparatus designed by the author is an oscilloscilloscope, which serves to measure the oscillation range (oscillations) of the pulse wave and determine the mean blood pressure. The latter is currently given great importance by a number of authors for evaluation of the functional state of the cardiovascular system, since the mean blood pressure is considered to be a value really corresponding to intra-arterial pressure.

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Fetal heart rate, arterial pressure, and blood volume responses to cortisol infusion

AJP Regulatory Integrative and Comparative Physiology ◽

10.1152/ajpregu.1987.253.6.r904 ◽

1987 ◽

Vol 253 (6) ◽

pp. R904-R909 ◽

Cited By ~ 9

Author(s):

C. E. Wood ◽

C. Y. Cheung ◽

R. A. Brace

Keyword(s):

Heart Rate ◽

Arterial Pressure ◽

Cardiovascular System ◽

Blood Volume ◽

Fetal Heart Rate ◽

Fetal Heart ◽

Plasma Renin ◽

Simultaneous Increase ◽

Plasma Norepinephrine ◽

Plasma Cortisol Concentration

The purpose of this study was to determine whether physiological amounts of cortisol affect the fetal cardiovascular system. Cortisol (4 micrograms/min) or the vehicle was infused intravenously for 5 h into six chronically catheterized sheep fetuses at 127-143 days gestation (term = 145-150 days). In the cortisol-infused animals, plasma cortisol concentration increased from 2.0 +/- 0.6 (SE) to 8.3 +/- 0.9 ng/ml. There was a concomitant decrease in fetal heart rate of 38 beats/min (P less than 1 X 10(-6)) and an increase in arterial pressure. Estimated blood volume decreased by 6% in the cortisol-infused fetuses compared with the vehicle-infused animals (P less than 1 X 10(-4]. In addition, plasma norepinephrine and epinephrine concentrations decreased to 70% of control at the end of the 5-h cortisol infusion, whereas plasma renin concentration decreased to 34% of control. The simultaneous increase in fetal arterial pressure and decrease in estimated blood volume suggest that fetal vascular resistance increased, whereas vascular compliance and/or nonstressed vascular volume decreased. However, this does not appear to be mediated by increases in circulating vasoconstrictor hormone concentrations or increased sympathetic tone. Thus the present study shows that physiological amounts of cortisol have significant effects on the fetal cardiovascular system but the mechanisms are unknown.

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Evaluation for roles of nitric oxide generated in the anteroventral third ventricular region in controlling vasopressin secretion and cardiovascular system of conscious rats

Acta Endocrinologica ◽

10.1530/eje.0.1430523 ◽

2000 ◽

pp. 523-533 ◽

Cited By ~ 15

Author(s):

K Yamaguchi ◽

K Watanabe ◽

K Yamaya

Keyword(s):

Nitric Oxide ◽

Heart Rate ◽

Arterial Pressure ◽

Cardiovascular System ◽

Plasma Osmolality ◽

Cardiovascular Responses ◽

Prostaglandin E ◽

Adjacent Area ◽

Conscious Rats ◽

Cardiovascular Variables

OBJECTIVE: To examine local actions of nitric oxide (NO) on the neural mechanisms controlling the release of vasopressin (AVP) and the cardiovascular system in the anteroventral third ventricular region (AV3V), a pivotal area for autonomic functions, and to pursue the problem of whether it may have any role in the AVP and cardiovascular responses evoked by plasma hypertonicity or by increased prostaglandin E(2) (PGE(2)) in the AV3V - one possible factor implicated in osmotic responses. METHODS: We infused NO-related agents into the AV3V, its adjacent area, the nucleus of the vertical limb of the diagonal band (VDB), or into the lateral cerebral ventricle of conscious rats, monitoring effects on plasma AVP, osmolality, sodium, potassium and chloride, arterial pressure and heart rate in the presence or absence of an osmotic or PGE(2) stimulus. The infusion sites were determined histologically. RESULTS: Infusion of L-arginine, the substrate of NO synthase (NOS), into the AV3V structures such as the median preoptic nucleus and periventricular nucleus produced dose-related increases in plasma AVP, arterial pressure and heart rate 5 or 15 min later, whereas infusion of D-arginine (which is not a substrate for NO synthesis) was without significant effect on these variables. Plasma osmolality or electrolytes were not changed by these treatments. The AV3V infusion of sodium nitroprusside (SNP), a spontaneous releaser of NO, also induced dose-dependent augmentations of plasma AVP, without evoking remarkable alteration in the cardiovascular parameters. The infusion of L- or D-arginine into the VDB affected none of the variables significantly. When applied intracerebroventricularly, L-arginine caused only increases in plasma AVP, whereas SNP caused only reductions in arterial pressure, leaving other variables at stable values. The effects of AV3V L-arginine on plasma AVP and the cardiovascular variables were abolished by N(G)-nitro-L-arginine methyl ester (L-NAME), a potent inhibitor of NOS, applied 15 min before. In contrast, infusion of L-NAME to the AV3V did not exert a significant effect on the responses of plasma AVP or cardiovascular variables to AV3V application of PGE(2) or i.v. infusion of hypertonic NaCl. The infusion of L-NAME alone did not affect plasma variables including AVP, although it tended to increase basal arterial pressure and heart rate. CONCLUSION: These results suggest that NO generated in or near the AV3V may act to enhance AVP release, arterial pressure and heart rate, but it may not play an essential role in eliciting the responses of these variables to osmotic or PGE(2) stimuli.

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