Diversity of non-palpable breast cancer. Timely diagnosis, adequate treatment and prevention

2021 ◽  
pp. 34-40
Author(s):  
N. I. Rozhkova ◽  
I. I. Burdina ◽  
S. B. Zapirova ◽  
P. G. Labazanova ◽  
M. L. Mazo ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Screening ◽  
Mammary Cancer ◽  
Diagnostic Methods ◽  
Breast Diseases ◽  
High Tech ◽  
Adequate Treatment ◽  
X Ray ◽  
Palpable Breast ◽  
Power Radiation

The goal. To show the variety of manifestations of non-palpable breast cancer, which create difficulties in diagnostics and the choice of treatment tactics, to focus on the need to accelerate the introduction of the latest organ-saving treatment and diagnostic technologies and prevention into the system of mammary cancer screening. The main provisions. The epidemiology of cancer, risk factors, positive trends in mammary cancer screening in Russia are presented. A description is given of the diversity of X-ray sonographic and molecular biological manifestations of non-palpable breast cancer based on the results of the analysis of a complex clinical X-ray sonographic pathomorphological and molecular genetic examination of 1,212 patients with clinically latent breast diseases, including 708 patients with non-palpable cancer of various molecular subtypes, manifested by a variety of options – a nodular growth (40.1%), an accumulation of microcalcifications (17.5%), a site of local heavy rearrangement of the structure (31.2%), cancer accompanied by pathological secretion (6.6%), X-ray negative cancer (4.6%). When distributed by stages, 70.3% had T1N0M0, 25% had TisN0M0 and microinvasive cancer. For differential diagnosis, high-tech radiological techniques were used – 3D X-ray and ultrasound tomosynthesis. Effective preoperative diagnostics allowed for adequate organ-saving treatment, including oncoplastic surgery, high-power radiation therapy and modern targeted drug treatment, timely rehabilitation and prevention. Conclusion. Non-palpable breast cancer has many faces. Knowledge of the variants of its manifestations and the use of modern diagnostic methods are necessary for mammary cancer screening, which creates the preconditions for adequate timely organ-saving treatment that preserves the life of patients and its quality.

Diagnosis of breast diseases under the assisted reproductive technologies programme

2020 ◽  
Vol 19 (4) ◽  
pp. 70-74
Author(s):  
L.D. Belotserkovtseva ◽  
◽  
N.V. Klimova ◽  
L.V. Kovalenko ◽  
V.V. Danilogorskaya ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Assisted Reproductive Technologies ◽  
Reproductive Technologies ◽  
The State ◽  
Diagnostic Methods ◽  
Breast Diseases ◽  
Old Patients ◽  
Core Needle ◽  
X Ray ◽  
Radiation Imaging

Objective. To study the state of the breasts in women who undergo assisted reproductive technologies treatment, using modern methods of radiation imaging. Patients and methods. Pre- and prospective examination and analysis of the data of radiation imaging of the breasts of 220 women, having tubal factor infertility in combination with benign mammary dysplasia, who have successful or unsuccessful experience of participation in assisted reproductive technology programmes. The average age of patients was 42.5 years. Assessment points were: breast tissue density according to the findings of ultrasound, mammography and tomosynthesis, presence of clustered microcalcifications, presence of benign dysplastic processes and fibroadenomas of the breasts. Results. In the group of 35–39-year old patients, the most common pathological processes were fibrocystic mastopathy and fibroadenomas. The main diagnostic methods were ultrasound visualization and US-controlled core-needle vacuum-assisted biopsy. In the group of 40–44-year old women, the predominant pathological process was microcalcification clusters alongside high mammographic density. The main diagnostic methods were digital x-ray tomosynthesis and X-ray-guided core-needle vacuum-assisted biopsy. In the group of 45–49-year old women, cases of breast cancer were diagnosed. 12 women in this group had breast implants. Conclusion. Hormonal medication used in assisted reproductive technologies under the protocols of in-vitro fertilization and intracytoplasmatic sperm injection influence the state of the breasts, increasing a risk of developing diffuse benign mammary dysplasias and, quite possible, a risk of developing breast cancer later in life. Key words: breast diseases, assisted reproductive technologies, tomosynthesis, mammotome, clustered microcalcifications

First experience with MRI-guided vacuum aspirated breast biopsy

2020 ◽  
pp. 25-31
Author(s):  
M. L. Mazo ◽  
O. E. Jacobs ◽  
O. S. Puchkova ◽  
M. V. Feldsherov ◽  
E. V. Kondratyev
Keyword(s):  
Breast Cancer ◽  
Breast Augmentation ◽  
Breast Biopsy ◽  
Breast Mri ◽  
Breast Tumors ◽  
High Tech ◽  
X Ray ◽  
Vacuum Aspiration ◽  
Mri Guided ◽  
Aesthetic Breast

The rate of detection of breast cancer by MRI, while other methods of radiological diagnosis are not sufficiently informative, ranges from 5.2 to 26.3 per cent. Suspicious breast tumors of category BI-RADS 4, 5 show morphological image-guided biopsy verification, in particular MRI with contrast. Purpose. To show the possibilities and features of carrying out MRI-guided vacuum breast biopsy, including after aesthetic breast augmentation. Material and methods. A comprehensive X-ray, ultrasound and MRI examination of 54 women aged between 28 and 70 years with different breast tumors was conducted. Of these, five were detected only by breast MRI with contrast, and were morphologically verified by MRI-guided vacuum aspiration biopsy. Results. 14 of the 54 patients with breast mass were diagnosed with breast cancer and 26 were diagnosed with benign diseases. The effectiveness of comprehensive examination and low-invasive high-tech MRI-guided procedures in early refined screening for breast cancer, including after aesthetic breast augmentation, has been demonstrated. MRI-guided vacuum-assisted breast biopsy is a fast, safe and accurate diagnostic method of morphological verification of suspicious breast tumors that do not have X-ray and ultrasound.

X-Ray Mammography for Breast Cancer Screening

1988 ◽  
Vol 39 (5) ◽  
pp. 192-194
Author(s):  
Michael Fitzgerald
Keyword(s):  
Breast Cancer ◽  
Cancer Screening ◽  
Breast Cancer Screening ◽  
X Ray

scholarly journals Breast Cancer Screening Among Medical Staff in Tehran, Iran: Improvement of Early Detection

2020 ◽  
Author(s):  
Hossein Yahyazadeh ◽  
Marzieh Beheshti ◽  
Azita Abdollahinejad ◽  
Maria Hashemian ◽  
Narges Sistany Allahabad ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Screening ◽  
Early Detection ◽  
Breast Cancer Screening ◽  
Medical Staff ◽  
Demographic Data ◽  
Cross Sectional Study ◽  
Breast Diseases ◽  
Cross Sectional ◽  
Screening Programs

Breast cancer is the most prevalent Iranian female malignancy. Breast screening reduces the number of malignant breast diseases. We aimed to assess the results of the pilot breast cancer screening on early detection in female medical staff in Milad Hospital, Tehran, Iran. A cross-sectional study. Female medical staff from Milad Hospital, Tehran, Iran, were examined by a specialist in 2016. A checklist, including demographic data, was completed by the participants. If necessary, they referred to as sonography or mammography. Data were analyzed using SPSS software. Of 746 people enrolled, 137 had no pathological point, 609 had suspicious or positive findings that were referred for further investigation, 449 had normal findings, and 7 had suspicious mass and were biopsied, 6 were benign. One case had primary invasive cancer. Since screening for breast cancer helps to early detection of this disease, the implementation of cancer screening programs should be on the priority of health authorities.

scholarly journals What is the effect of advanced diagnostic methods on sensitivity and survival in the multiple breast cancers? A systematic analysis and comparison

2021 ◽  
Vol 12 (7) ◽  
pp. 138-145
Author(s):  
Hasan Zafer Acar ◽  
Nazmi - Ozer
Keyword(s):  
Breast Cancer ◽  
Molecular Structure ◽  
Cancer Screening ◽  
Treatment Plan ◽  
Diagnostic Methods ◽  
Breast Cancers ◽  
Recurrence Rates ◽  
Systematic Analysis ◽  
Screening Programs ◽  
Conventional Methods

The sensitivities of the advanced diagnostic methods appear to be higher than the conventional methods and do have the potential to prolong survival, in multiple (multifocal and multicenter) breast cancers. Thus, the aim of this study is to compare the sensitivities of advanced and conventional diagnostic methods and to reveal their effects on survival. The studies published about diagnosis and treatment methods in multiple breast cancer in literature were searched, analyzed, and the sensitivities obtained with advanced and conventional diagnostic methods were compared, and the results were evaluated statistically. The sensitivity obtained with the advanced diagnostic methods in multiple breast cancers was found to be significantly higher than the conventional methods (p <0.05). The high sensitivities obtained with advanced diagnostic methods were found to have a high potential for survivial prolongation in multiple breast cancers. The use of advanced diagnostic methods in breast cancer screening programs, the investigation of tumor foci with molecular methods, increases the rate of diagnosis in multiple breast cancers. In the treatment of multiple breast cancers, a personalized treatment plan is made with the diagnosis of the molecular structure of the tumor foci. Thus, the recurrence rates are reduced, the survival is prolonged.

Fine Needle Aspiration Cytological Study of Palpable Breast Lump Among Sample of Iraqi Women Attending Al Elweiya Teaching Hospital Breast Cancer Screening Unit in Baghdad

2021 ◽  
Vol 24 (04) ◽  
Author(s):  
Mohamed Yehya Abdul Hasan ◽  
Ban Abdul Ridha Al Hashimi ◽  
Najim Abid Issa Al-Khalidy ◽  
Marwah Imad Al Ameen ◽  
Jawad Kadhim Al Diwan
Keyword(s):  
Breast Cancer ◽  
Cancer Screening ◽  
Fine Needle Aspiration ◽  
Cytological Study ◽  
Needle Aspiration ◽  
Breast Lump ◽  
Fine Needle ◽  
Screening Unit ◽  
Iraqi Women ◽  
Palpable Breast

Benign Breast Diseases in Breast Cancer Screening Programs in Italy (2000-2001)

2004 ◽  
Vol 90 (6) ◽  
pp. 547-549 ◽  
Author(s):  
Sandra Fabbri ◽  
Elisa Perfetti ◽  
Deanna Govoni ◽  
Simonetta Bianchi ◽  
Beniamino Brancato ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Screening ◽  
Breast Cancer Screening ◽  
Breast Diseases ◽  
Screening Programs ◽  
Benign Breast Diseases

scholarly journals Awareness about breast cancer and mammogram among women attending outpatient clinics, Ain Shams University Hospitals, Egypt

2019 ◽  
Vol 94 (1) ◽  
Author(s):  
Ayat F. Manzour ◽  
Dina A. Gamal Eldin
Keyword(s):  
Breast Cancer ◽  
Risk Factors ◽  
Cancer Screening ◽  
Breast Cancer Screening ◽  
Screening Method ◽  
Outpatient Clinics ◽  
Breast Diseases ◽  
Poor Knowledge ◽  
Attitude And Practice ◽  
Knowledge Attitude And Practice

Abstract Background Breast diseases in women, whether benign or malignant, are very commonly encountered. The breast is the commonest site for female cancer in Egypt (38.8%). Breast cancer screening can reduce morbidity and mortality and improve the survival rate for this malignancy. Mammogram can be used as a screening technique beside its role as diagnostic, especially in women over 40 years of age. Objectives To assess knowledge, attitude and practice regarding breast cancer and awareness about mammogram as a screening method among a group of females attending Ain Shams University outpatient clinics. Methods A cross-sectional study was performed from August to September 2017. A systematic random sample was taken from attending females (18–70 years) in Ain Shams University outpatient clinics (Internal Medicine, Surgery, Pediatrics Hospital, and Maternity hospital). They were interviewed using a questionnaire inquiring about sociodemographic background, participants’ knowledge, attitude, and practice towards breast cancer and its screening. Results The mean age ± SD of attending females (18–70 years) was 37 ± 11 years. Most study participants had correct information about mammography. They showed poor knowledge level about risk factors. Mass media such as TV and internet were identified as the main source of information on breast cancer by 43% and 23.9%, respectively. In general, participants had positive attitude towards breast cancer screening by mammography. Around 90% agreed that mammogram was the best way to find a very small lump in the breast, and 91.4% agreed that women who have regular screening by mammogram have better disease outcome than those who do not screen. Regarding mammography practice rate, a small percent of participants (8.1%) was advised by their doctors to conduct a screening mammography. The level of knowledge was significantly and positively correlated with their attitude towards breast cancer screening. Conclusion The poor knowledge and practices of women illustrate the need for health education program directed to Egyptian females to improve their knowledge about breast cancer—especially its risk factors—and its screening. Using TV and Internet as media for spreading information about this disease is crucial.

scholarly journals Breast cancer screening during the adverse COVID-19 epidemiological situation

2021 ◽  
Vol 8 (3) ◽  
pp. 34-44
Author(s):  
K. S. Drzhevetskaya ◽  
G. P. Korzhenkova
Keyword(s):  
Breast Cancer ◽  
Cancer Screening ◽  
Breast Cancer Screening ◽  
Medical Personnel ◽  
Screening Mammography ◽  
Breast Diseases ◽  
Expert Review ◽  
Mobile Mammography ◽  
Mammographic Examination ◽  
Epidemiological Situation

Purpose of the study. To evaluate the results of breast cancer screening (BC) in the conditions of an unfavorable epidemiological situation COVID‑19 based on the analysis of the BC screening project in the Kaluga Region.Patients and methods. Screening system: creation and implementation in practice of mobile mammography complexes (MMC); training of medical personnel in the method of conducting a standardized mammographic examination (ME); quality control of ME; "Cloud" storage and software development for archiving patients; an independent review of mammograms by certified specialists; expert review of images in case of discrepancies in diagnoses; referral of patients diagnosed with BI-RADS IV and V to the regional oncological dispensary for further examination and treatment. From 04.2018 to 12.2020 patients were examined on MMC according to the BC screening protocol. We examined 47367 patients over the age of 40 years. SD 57.66 ± 8.17 years (38-93). During the COVID‑19 pandemic, imaging of breast diseases must be carried out in compliance with all safety regulations for both personnel and patients. Balancing the need to avoid delays in diagnosing BC while preventing infection requires careful attention to personal protective equipment, handling of diagnostic equipment, diagnostic facilities, and physical distancing and vigilance to maintain these measures.Results. From 07.2020 to 11.2020: a total of 10736 studies have been carried out. In the context of new coronavirus infection, we noted an increased demand among patients wishing to undergo BC screening. The flow of patients over the same period of previous years was less, which indicates the demand and justification for screening mammography and the use of MMC in an unfavorable epidemiological situation. 174 patients received category BI-RADS IV-V and were referred for a follow-up examination and required treatment at an oncological dispensary. In 39 patients (22.4 %), BC was verified, and appropriate treatment was carried out. In 135 cases, benign processes were verified.Conclusion. BC screening should not be stopped against the backdrop of the COVID‑19 epidemic since a delay in BC diagnosis later threatens to reveal more voluminous processes with a worse prognosis for treatment and rehabilitation than timely detected changes in the mammary glands in the early preclinical stages of the disease.

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