THE USE OF SOLID AND LIQUID MEDIUM TO STUDY THEEFFECTS OF HEAVY METALS ON THE GROWTH OF CANDIDA ALBICANS

2006 ◽  
Vol 5 (2) ◽  
pp. 170-182
Author(s):  
iMakia M.Al-Hejuje ◽  
Mohammed H.Khudor
1978 ◽  
Vol 64 (3) ◽  
pp. 143-146 ◽  
Author(s):  
M. Gunasekaran ◽  
Walter T. Hughes

2020 ◽  
Vol 15 (2) ◽  
pp. 26-32
Author(s):  
Uchenna Jude Okobo ◽  
Nwadibe Eze Chibuzor ◽  
Uchenna Kalu Akpi

1994 ◽  
Vol 302 (2) ◽  
pp. 535-538 ◽  
Author(s):  
J Alvarez-Bravo ◽  
S Kurata ◽  
S Natori

Previously, we identified a core undecapeptide of sapecin B having antimicrobial activity. Based on the structure of this peptide, we systematically synthesized peptides consisting of terminal basic motifs and internal oligo-leucine sequences and examined their antimicrobial activities. Of these peptides, RLKLLLLLRLK-NH2 and KLKLLLLLKLK-NH2 were found to have potent microbicidal activity against Staphylococcus aureus, Escherichia coli, methicillin-resistant S. aureus and Candida albicans in liquid medium. We also synthesized the D-enantiomer of KLKLLLLLKLK-NH2. This enantiomer was resistant to tryptic digestion and persisted longer in the culture medium, showing greater antimicrobial activity than the original peptide.


2012 ◽  
Vol 12 (1) ◽  
pp. 34 ◽  
Author(s):  
Reginawanti Hindersah ◽  
Dedeh Hudaya Arief ◽  
Soetijoso Soemitro ◽  
Lukman Gunarto

The contamination of toxic heavy metal Cadmium (Cd) in soils will be endanger the human health because it ismore available comparing to another toxic heavy metals. One method of Cd-contaminated soil bioremediation isusing exopolysachharide-producing bacteria Azotobacter. Exopolysachharides (EPS) can mobilize Cd through theformation of complex Cd-EPS which sequentially can increase the availability of Cd for plants uptake. A laboratoryexperiment has been done to study the EPS production and the viability of six Azotobacter isolates in the liquidculture containing 0.01, 0.1, and 1 mM CdCl2. The bacteria were cultured in liquid medium with and without CdCl2 for72 hours at room temperature. The EPS production was determined by gravimetric method after precipitationusing acetone and centrifugation at 7000 rpm. The result was that all of Azotobacter isolates produce EPS in thepresence of CdCl2. In the culture with 1 mM CdCl2, the density of Azotobacter sp. isolate BS3, LK5, LKM6 increasedsignificantly, and that of isolate LH16 decreased. No significant effect of CdCl2 on the density of isolate BS2 andLH15. This research suggested that some Azotobacter isolates were relatively resistence to the Cd and could bedeveloped as biological agents in Cd-contaminated soil bioremediation.


Author(s):  
Ismael Acosta Rodríguez ◽  
Juan Fernando Cárdenas-González ◽  
Víctor Manuel Martínez Juárez ◽  
Adriana Rodríguez Pérez ◽  
María de Guadalupe Moctezuma Zarate ◽  
...  

2020 ◽  
Vol 18 (3) ◽  
pp. 225-228
Author(s):  
Valentina V. Novikova ◽  
Natalya A. Pulina ◽  
Fedor V. Sobin ◽  
Konstantin V. Lipatnikov

Among more than 600 types of micromycetes of clinical importance, fungi of the Candida spp. are the most common pathogen, causing different forms of candidiasis (superficial candidiasis, visceral candidiasis). The aim of this work was to determine the antifungal activity of new derivatives of 4-(het)aryl-2,4-dioxobutanoic acids, in relation to typical strains of Candida yeast and to identify the most active compounds. The study of the antifungal activity of the compounds was carried out by the micromethod of double serial dilutions in a liquid medium. The antifungal activity of 6 compounds in relation to 4 typical strains of Candida spp. was studied; the high antimycotic activity of 4 compounds against the Candida albicans strain was established. A leader compound with high antifungal activity for all the studied strains was revealed. The prospects of studying the modified compounds of this series are shown.


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