scholarly journals Online tools to easily build augmented reality models of biomolecules that run right on the web

Author(s):  
Fabio Cortés Rodríguez ◽  
Matteo Dal Peraro ◽  
Luciano Abriata

Abstract. Several groups developed in the last years augmented and virtual reality (AR/VR) programs and apps to visualize 3D molecules, most rather static, limited in content, and requiring software installs, some even requiring expensive hardware. During the Covid-19 pandemic, our team launched moleculARweb (https://molecularweb.epfl.ch), a website that offers interactive content for chemistry and structural biology education through commodity web-based AR that works on consumer devices like smartphones, tablets and laptops. Among thousands of users, teachers increasingly request more biological macromolecules to be available, a demand that we cannot satisfy individually. Therefore, to allow users to build their own material, we built a web interface where any user can build any online AR experience in few steps starting from a PDB structure or from virtual objects/scenes exported from VMD. The website also returns a WebXR session for viewing and manipulating the model in high-end immersive VR headsets with web browsers, here tested on the ~400 USD Oculus Quest 2. The tool is accessible at https://molecularweb.epfl.ch/pages/pdb2ar.html.

2021 ◽  
Author(s):  
Fabio Cortés Rodríguez ◽  
Matteo Dal Peraro ◽  
Luciano Abriata

Several groups developed in the last years augmented and virtual reality (AR/VR) programs and apps to visualize 3D molecules, most rather static, limited in content, and requiring software installs, some even requiring specialized hardware. During the Covid-19 pandemic, our team launched moleculARweb (https://molecularweb.epfl.ch), a website that offers interactive content for chemistry and structural biology education through web-based AR that works on consumer devices like smartphones, tablets and laptops. The website quickly got thousands of student and teacher users, a substantial fraction of them accessing from their homes given the pandemic. Teachers have been increasingly requesting more biological macromolecules to be available in AR, a demand that we cannot satisfy individually. Therefore, to allow them to build their own material, and also to help us expedite development of activities, we built a web interface where any user can build any online AR experience in few steps starting from a PDB structure or from virtual objects/scenes exported from VMD. We here briefly describe the tool, that is accessible at https://molecularweb.epfl.ch/pages/pdb2ar.html.


2020 ◽  
Author(s):  
Fabio Cortés Rodríguez ◽  
Gianfranco Frattini ◽  
Lucien Krapp ◽  
Hassan Martinez-Huang ◽  
Diego Moreno ◽  
...  

<p>Here we introduce <i>MoleculARweb</i>, a purely web-based AR platform for chemistry, molecular and structural biology education that runs out of the box in regular web browsers in ordinary computers, laptops, tablets and smartphones. Through regular-printed markers recognized via the device’s webcam, students and teachers can handle molecules in an AR environment to interactively explore their structure, dynamics and interactions. The release version of <i>MoleculARweb</i> features over 20 activities covering topics about molecular shapes, atomic and molecular orbitals, acid-base equilibria and hydrogen bonding, protein and nucleic acid structures, X-ray diffraction and electron microscopy, and molecular mechanics; applicable from high school to early university levels. <i>MoleculARweb</i> is freely available without registration at <a href="https://molecularweb.epfl.ch">https://MoleculARweb.epfl.ch</a> in 6 languages. </p>


2020 ◽  
Author(s):  
Fabio Cortés Rodríguez ◽  
Gianfranco Frattini ◽  
Lucien Krapp ◽  
Hassan Martinez-Huang ◽  
Diego Moreno ◽  
...  

<p>Here we introduce <i>MoleculARweb</i>, a purely web-based AR platform for chemistry, molecular and structural biology education that runs out of the box in regular web browsers in ordinary computers, laptops, tablets and smartphones. Through regular-printed markers recognized via the device’s webcam, students and teachers can handle molecules in an AR environment to interactively explore their structure, dynamics and interactions. The release version of <i>MoleculARweb</i> features over 20 activities covering topics about molecular shapes, atomic and molecular orbitals, acid-base equilibria and hydrogen bonding, protein and nucleic acid structures, X-ray diffraction and electron microscopy, and molecular mechanics; applicable from high school to early university levels. <i>MoleculARweb</i> is freely available without registration at <a href="https://molecularweb.epfl.ch">https://MoleculARweb.epfl.ch</a> in 6 languages. </p>


2019 ◽  
Vol 11 (7) ◽  
pp. 147 ◽  
Author(s):  
Masaki Kohana ◽  
Shinji Sakamoto ◽  
Shusuke Okamoto

Real-time web applications such as a virtual world require considerable computing resources. However, as the number of servers increases, so does the maintenance and financial cost. To share tasks among web browsers, the browsers must share data. Therefore, a network must be constructed among the web browsers. In this paper, we propose the construction of a web browser network based on the Barabasi–Albert model (BA model). We focus on a web-based multiplayer online game that requires higher frequent communication and significant computing resources. We attempt to optimize computing resource utilization for web browsers. We improve upon the method in our previous study, which constructed a network for a web-based virtual world, using only location information. When a new user logged into a world, the web browser connected to two other browsers whose users had a location close to that of the user. The experimental results of that method showed 50% data coverage, which was insufficient to display the game screen because the web browser displays the characters on the virtual world. In this study, we attempt to use the BA model to construct more efficient networks than those in the previous study to increase data coverage. Our new method uses the number of connections of the web browser and location information to calculate the probability of web browser selection. The experimental results show that the data coverage exceeds 90%, indicating significant improvement over the previous method.


2021 ◽  
Vol 8 ◽  
Author(s):  
Rodrigo V. Honorato ◽  
Panagiotis I. Koukos ◽  
Brian Jiménez-García ◽  
Andrei Tsaregorodtsev ◽  
Marco Verlato ◽  
...  

Structural biology aims at characterizing the structural and dynamic properties of biological macromolecules at atomic details. Gaining insight into three dimensional structures of biomolecules and their interactions is critical for understanding the vast majority of cellular processes, with direct applications in health and food sciences. Since 2010, the WeNMR project (www.wenmr.eu) has implemented numerous web-based services to facilitate the use of advanced computational tools by researchers in the field, using the high throughput computing infrastructure provided by EGI. These services have been further developed in subsequent initiatives under H2020 projects and are now operating as Thematic Services in the European Open Science Cloud portal (www.eosc-portal.eu), sending &gt;12 millions of jobs and using around 4,000 CPU-years per year. Here we review 10 years of successful e-infrastructure solutions serving a large worldwide community of over 23,000 users to date, providing them with user-friendly, web-based solutions that run complex workflows in structural biology. The current set of active WeNMR portals are described, together with the complex backend machinery that allows distributed computing resources to be harvested efficiently.


Transport ◽  
2020 ◽  
Vol 35 (5) ◽  
pp. 511-522
Author(s):  
Kumar Balaji ◽  
Muthusamy Selvam

This paper describes a new system – Vehicle Kit (VEKIT), which uses a secure web-based interface for the authentication and monitoring of Vehicular Ad-Hoc Network (VANET) infrastructure and for preventing environment pollution. This paper presents the hazards caused by the usage of bags made of plastic material and proposes the design of VEKIT, which is to be installed in the vehicles for reducing the usage of such carry bags up to 75%. The survey results prove that the proposed VEKIT approach is very much relevant to solve the pollution problem faced by various countries. This novel application adds value to the future VANET projects by helping the countries to prevent pollution. The web interface of VEKIT presented in the paper can also be used to monitor the vehicles for their authenticity. A secure architecture is proposed for the usage of VANET in transport related projects.


2019 ◽  
Vol 35 (20) ◽  
pp. 4179-4180 ◽  
Author(s):  
X Raymond Gao ◽  
Hua Huang

Abstract Summary Pleiotropy plays an important role in furthering our understanding of the shared genetic architecture of different human diseases and traits. However, exploring and visualizing pleiotropic information with currently publicly available tools is limiting and challenging. To aid researchers in constructing and digesting pleiotropic networks, we present PleioNet, a web-based visualization tool for exploring this information across human diseases and traits. This program provides an intuitive and interactive web interface that seamlessly integrates large database queries with visualizations that enable users to quickly explore complex high-dimensional pleiotropic information. PleioNet works on all modern computer and mobile web browsers, making pleiotropic information readily available to a broad range of researchers and clinicians with diverse technical backgrounds. We expect that PleioNet will be an important tool for studying the underlying pleiotropic connections among human diseases and traits. Availability and implementation PleioNet is hosted on Google cloud and freely available at http://www.pleionet.com/.


2020 ◽  
Vol 45 (2) ◽  
pp. 159-167
Author(s):  
Himadri Barman

This article looks at the implementation of a web-based support system for measuring the fielding performance in cricket using open source technologies. Front-end has been developed using HTML, CSS and JavaScript. The back-end uses MySQL as the database for storing fielding related data. PHP is used to interact with the MySQL database. The web-based support system which is named Field-o-meter can be used to record fielding data, display fielding data, compute fielding performance measure and generate reports. The system has facilities for different categories of users, viz., administrators, data entry operators and viewers. Users need to login to access the system. Data can be added, deleted, displayed and also edited with certain restrictions. Analysis reports may be viewed online. Fielding data can be downloaded in xls (MS Excel) format. Being an online system hosted on a web server, it can be accessed from anywhere with an Internet connection. The web-based support system is easy to use with a simply designed interface. The system’s interface gets adjusted to mobile devices and as such can be used with a mobile browser. The system has been tested successfully for all the leading web browsers—Google Chrome, Firefox, Microsoft Edge, Opera and Safari.


2014 ◽  
Vol 29 (2) ◽  
pp. 134-153 ◽  
Author(s):  
Andrés Fortier ◽  
Cecilia Challiol ◽  
Juan Lautaro Fernández ◽  
Santiago Robles ◽  
Gustavo Rossi ◽  
...  

AbstractThere is an increasing trend in moving desktop applications to web browsers, even when the web server is running on the same desktop machine. In this paper, we go further in this direction and show how to combine a web server, a web application framework (enhanced to support desktop-like Model–View–Controller interaction) and a context-aware architecture to develop web-based mobile context-aware applications. By using this approach we take advantage of the well-established web paradigm to design the graphical user interfaces (GUIs) and the inherent ability of the web to mash up applications with external components (such as Google Maps). On top of that, since the web server runs on the device itself, the application can access local resources (such as disk space or sensing devices, which are indispensable for context-aware systems) avoiding the sandbox model of the web browsers. To illustrate our approach we show how a mobile hypermedia system has been built on top of our platform.


2009 ◽  
Vol 13 (1) ◽  
Author(s):  
Kelly Fadel ◽  
David Olsen ◽  
Karina Hauser

The growing popularity of Internet-enabled commerce has produced increased demand for Information Technology (IT) professionals who are skilled in the development and management of data-driven, Web-based business applications. Many academic programs in information systems offer courses on relational database design and management, as well as courses on Web development using technologies such as PHP or Microsofts ASP.NET. However, such courses typically contain independent content, which tends to leave students with a fragmented understanding of how these technologies (i.e. the Web and relational databases) interact. In this paper, we present integrated instructional modules for teaching best practices in connecting advanced Web applications with a relational database backend. The objective of these modules is to provide students with a seamless context for developing both a relational database and a Web interface supporting database transactions.


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