scholarly journals The Relationship between Dietary Phosphorus Level and the Level of Plasma Inorganic Phosphorus of Chicks

1962 ◽  
Vol 41 (4) ◽  
pp. 1156-1163 ◽  
Author(s):  
E.E. Gardiner
1971 ◽  
Vol 51 (2) ◽  
pp. 445-450 ◽  
Author(s):  
E. E. GARDINER

Two factorial experiments were conducted to compare the dietary calcium requirements of two breeds of chickens and to determine the relationship between breed, dietary phosphorus level, and dietary calcium levels. Both experiments used two breeds of chickens (broiler crossbreds and Single Comb White Leghorns), two levels of added dietary phosphorus (0.18 and 0.36%), and six levels of added dietary calcium (experiment 1: 0.2, 0.4, 0.6, 0.8, 1.2, and 1.4%; experiment 2: 0.0, 0.3, 0.6, 0.9, 1.2, and 1.5%). Criteria observed included body weight (4-week), feed efficiency, mortality, and percent bone-ash. Breed and calcium level had a consistent significant effect on body weight, feed efficiency, and percent bone-ash. The breed × calcium interaction was significant for all the criteria measured, indicating that the Leghorn and broiler-type chickens differ in their dietary calcium requirements.


1969 ◽  
Vol 49 (2) ◽  
pp. 193-195 ◽  
Author(s):  
E. E. Gardiner

Male crossbred broiler-type chickens were fed graded levels of dietary phosphorus from hatching to 4 weeks of age. Plasma inorganic phosphorus and plasma inorganic calcium were determined on aliquots of blood plasma samples taken when the chickens were 4 weeks of age. The level of plasma inorganic phosphorus decreased when the chickens were fed low levels of dietary phosphorus. The level of plasma inorganic calcium was inversely related to the plasma inorganic phosphorus level. Regression equations were different for each of the four dietary phosphorus levels fed. The sum of plasma inorganic phosphorus and plasma inorganic calcium was very similar for the four treatments.


Author(s):  
Christin Volk ◽  
Benjamin Schmidt ◽  
Corinna Brandsch ◽  
Tabea Kurze ◽  
Ulf Schlegelmilch ◽  
...  

Abstract Context Hyperphosphatemia and high levels of fibroblast growth factor 23 (FGF23) are risk factors for cardiovascular events in patients with chronic kidney diseases. However, the impact of an inorganic phosphorus additive in healthy people is largely unknown. Objective We aimed to investigate the acute effect of excessive dietary phosphorus administered as sodium dihydrogen phosphate on the postprandial levels of Pi and FGF23 and the response to food. Methods This study was a double-blind placebo-controlled crossover study with 29 healthy male and female participants from the general community who were administered a single dose of either 700 mg phosphorus (NaH2PO4) or a sodium-adjusted placebo in combination with a test meal. Postprandial plasma levels of Pi and FGF23 were measured. Results Compared with placebo, oral phosphorus increased the plasma Pi level, which remained elevated during the ensuing 8 hours (at 480 minutes: 1.31 vs 1.16 mmol/l; P < 0.001), increased urinary Pi (iAUC0-480 789 vs 95 mmol/mmol; P < 0.001), reduced tubular Pi reabsorption (iAUC0-480 −31.5 vs −6.2; P < 0.001), decreased urinary calcium (iAUC0-240 30.6 vs 53.0 mmol/mmol; P = 0.009), and stimulated the release of parathyroid hormone (iAUC0-480 2212 vs 768 ng/l; P < 0.001). However, the FGF23 levels did not change. Postprandial levels of glucose, insulin, and lipids were not substantially affected by phosphorus vs placebo. Conclusion An oral phosphorus load can induce elevated postprandial levels of circulating Pi for hours in healthy subjects, despite rapid homeostatic counterreactions. FGF23 levels and the postprandial response to food were not affected.


1984 ◽  
Vol 246 (2) ◽  
pp. E168-E173 ◽  
Author(s):  
Y. Tanaka ◽  
H. F. DeLuca

The effects of thyroparathyroidectomy, parathyroid hormone, 1,25-dihydroxyvitamin D3, dietary calcium, dietary phosphorus, age, and sex on the renal 25-hydroxyvitamin D3 1- and 24-hydroxylases measured in vitro in rats have been studied. Thyroparathyroidectomy of vitamin D-deficient rats abolishes 25-hydroxyvitamin D3 1-hydroxylase activity, and administration of bovine parathyroid extract to the thyroparathyroidectomized rat restores diminished 1-hydroxylase activity. Both suppression and restoration of the enzyme activities require many hours (18-24 h) independent of rapid changes in serum calcium and inorganic phosphorus levels in response to these manipulations. Administration of 1,25-dihydroxyvitamin D3 to vitamin D-deficient rats suppresses 25-hydroxyvitamin D3 1-hydroxylase activity and stimulates 25-hydroxyvitamin D3 24-hydroxylase activity within 48 h. Rats maintained on a low-calcium or a low-phosphorus diet with a daily supplement of 20 IU vitamin D3 show high 25-hydroxyvitamin D3 1-hydroxylase activity and low 24-hydroxylase activity as compared with rats similarly treated but fed a diet containing adequate calcium or adequate phosphorus. When vitamin D-sufficient rats having suppressed renal 25-hydroxyvitamin D3 1-hydroxylase activity are placed on a low-calcium vitamin D-deficient diet for 7 days, the 1-hydroxylase activity is greatly stimulated in 6-wk-old rats but much less so in rats with advancing age.


1964 ◽  
Vol 82 (1) ◽  
pp. 111-114 ◽  
Author(s):  
E. R. Miller ◽  
D. E. Ullrey ◽  
C. L. Zutaut ◽  
J. A. Hoefer ◽  
R. W. Luecke

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