Serum Magnesium Levels in Exacerbation of COPD: A Single Centre Prospective Study from Kashmir, India.

JMS SKIMS ◽  
2010 ◽  
Vol 13 (1) ◽  
pp. 15-19
Author(s):  
Bashir Ahmed Shah ◽  
Muzafar Ahmed Naik ◽  
Sajjad Rajab ◽  
Syed Muddasar ◽  
Ghulam Nabi Dhobi ◽  
...  
Keyword(s):  
Acute Exacerbation ◽  
Serum Magnesium ◽  
Stage Iii ◽  
Advanced Stage ◽  
Copd Exacerbation ◽  
Post Discharge ◽  
Duration Of Symptoms ◽  
Copd Patients ◽  
Exacerbation Of Copd ◽  
Time Of Admission

Objective: To study the significance of serum magnesium levels during COPD exacerbation and stability.Materials & Methods: The patient population consisted of all patients of COPD admitted as acute exacerbation as defined by the Anthonisens criteria, from June 2006 to may 2008. Same patients one month post discharge presenting to the OPD for routine check up as stable COPD served as controls. Results: A total number of 77 patients of COPD presenting as acute exacerbation were included in the study. The incidence of Hypomagnesaemia was 33.8% at admission; 5% at discharge and 4% at one month of post discharge in COPD patients. The mean serum magnesium levels were significantly lower in cases than controls (1.88±0.67mg/ dl V/S 2.3±0.36mg/dl; p<0.0001). Also, hypomagnesemia was present in higher number of cases (22/77, 33.8%) compared to controls, 3/75, 4.0%; (p<0.0001). Patients of COPD with acute exacerbation and hypomagnesemia, had longer duration of symptoms and had advanced stage III of COPD (p<0.001); and had raised mean corpuscle volume (p<0.045) and longer hospital stay (p<0.008).  Conclusion: We conclude COPD exacerbation is associated with hypomagnesemia. The duration of symptoms of more than 8 days, advanced stage of COPD (stage III) and raised MCV were associated with hypomagnesemia. We recommend to monitor serum magnesium levels in COPD patients with acute exacerbation at the time of admission and during their stay in the hospital.J Med Sci.2010;13(1);15-19

scholarly journals Serum magnesium level in acute exacerbation of the chronic obstructive pulmonary disease

2020 ◽  
Vol 11 (SPL4) ◽  
pp. 2231-2235
Author(s):  
Nitin N Jadhav ◽  
Patange Aparna ◽  
Patil Shilpa ◽  
Pardesi A T
Keyword(s):  
Acute Exacerbation ◽  
Serum Magnesium ◽  
Magnesium Level ◽  
Stage Ii ◽  
Control Group ◽  
Chronic Obstructive ◽  
Copd Exacerbation ◽  
Serum Magnesium Level ◽  
Copd Patients ◽  
Number Of Patients

In this hospital based Case Control study, the patient population consisted of 100 patients of COPD admitted as an acute exacerbation, maximum number of patients of acute exacerbation 45% was in the age of 61-70 years, mean age was 66.44 ± 8.19 years. 74 patients were males, 71% of COPD patients were chronic smokers, 45 (45%) patients were in stage II, and 72% of patients of COPD exacerbation had hypomagnesaemia. In the control group, 99% of patients had normomagnesaemia. The incidence of hypomagnesaemia was 78% with acute exacerbation. The correlation of serum magnesium levels in exacerbation patients moreover, serum magnesium level stable COPD patients was significantly important. There was a significant correlation between hypomagnesaemia and GOLD staging in stage II and stage III, with a non-significant correlation between hypomagnesaemia and stage I and stage IV. The study concludes that COPD exacerbation is associated with hypomagnesaemia. Further studies are needed to find out the correlation between the staging of COPD and serum magnesium levels, and the effect of magnesium therapy in COPD exacerbation patients with hypomagnesaemia. Also, further studies are needed to find out possible aetiology of hypomagnesaemia in COPD exacerbation.

Study of serum magnesium levels in acute exacerbation of COPD

2016 ◽  
Vol 3 (1) ◽  
pp. 56-64
Author(s):  
M.G.Krishna Murthy ◽  
◽  
Tarigopula Pramod Kumar ◽  
M. Kiran kumar
Keyword(s):  
Acute Exacerbation ◽  
Serum Magnesium ◽  
Acute Exacerbation Of Copd ◽  
Exacerbation Of Copd

“RESPIRATORY VIRAL INFECTION: AN UNDERRATED ENTITY THAT NEED TO CONSIDER IN MANAGEMENT OF ACUTE EXACERBATION OF COPD”

2021 ◽  
pp. 6-8
Author(s):  
Gyan Singh Meena ◽  
Ajith Kumar M S ◽  
Shashank Sharma ◽  
SP Agnihotri
Keyword(s):  
Acute Exacerbation ◽  
Viral Infections ◽  
Respiratory Viruses ◽  
Cross Sectional Study ◽  
Viral Etiology ◽  
Cross Sectional ◽  
Acute Exacerbation Of Copd ◽  
Medical College ◽  
Copd Patients ◽  
Exacerbation Of Copd

BACKGROUND: Acute exacerbation of COPD (AECOPD) is one of the most common cause of hospital admission. It causes signicant morbidity, mortality and inexorable decline in ling function. Many exacerbations are believed to be due to upper and/ lower respiratory tract viral infections, but the incidence of these infections in patients with COPD is still undetermined. Objectives of the study are-(a) To nd out the viral etiology in patients having acute exacerbation of COPD. (b) To correlate the severity of COPD patients having exacerbations with viral etiology. METHODS: This cross-sectional study was carried out on 70 AECOPD patients admitted in department of Respiratory Medicine, Institute of Respiratory Diseases, SMS Medical College, Jaipur during July 2019–June 2020. Demographic and clinical parameters were recorded from each patient during admission. Twin nasopharyngeal/oropharyngeal swabs were collected and are tested for Respiratory viruses via RT-PCR. RESULTS: Respiratory viruses were detected in 15 of 70 (21.42%) patients during exacerbations of COPD. The viruses detected were inuenza (10%), rhinovirus (5.71%), adenovirus (4.29%) and RSV (1.42%). Majority of the patients had exacerbations in severe COPD subgroup, had duration of hospital stay of more than or equal to 5 days, had one episode of acute exacerbation per year and 5, 9, 11 respiratory viruses were detected in this group respectively. CONCLUSION: Viral infections seem to contribute to the exacerbations of COPD in our settings and should be strongly considered in the management of such patients. Considering appropriate antiviral therapy can timely reduce morbidity in an event of an inuenza viral exacerbation.

Effect of the Air Pollution on Acute Exacerbation of COPD Patients in Shanghai

CHEST Journal ◽  
2016 ◽  
Vol 149 (4) ◽  
pp. A343
Author(s):  
Xian Wen Sun ◽  
Qing Yun Li ◽  
Pei Li Chen ◽  
Lei Ni ◽  
Lei Ren ◽  
...  
Keyword(s):  
Air Pollution ◽  
Acute Exacerbation ◽  
Acute Exacerbation Of Copd ◽  
Copd Patients ◽  
Exacerbation Of Copd
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