Case of Metastasis of Alveolar Soft Part Sarcoma Lower Limb To Brain Diagnosed on Squash Cytology

JMS SKIMS ◽  
2017 ◽  
Vol 20 (2) ◽  
pp. 108
Author(s):  
Sumat Ul Khurshid ◽  
Iqbal Lone ◽  
Imza Feroz ◽  
Wajahat Mir
Keyword(s):  
Lower Limb ◽  
Soft Part ◽  
Low Density ◽  
Parietal Region ◽  
Limb Weakness ◽  
Left Lower Limb ◽  
History Of ◽  
One Year ◽  
The Brain ◽  
Space Occupying Lesion

A 19‑year‑old male patient was admitted, after experiencing occasional headaches during the previous 6 months. The patient's headaches had become progressively more severe 1 month prior to admis­sion to hospital, and were associated with right upper limb weakness. As revealed by cranial computed tomog­raphy, a high‑density lesion was observed in the left parietal region [CT values, 52 Houns field units, (HU)] and a peripheral low‑density edematous zone was visible.(figure a) . The medical history of the patient included an indolent 4x4 cm subcutaneous iliac mass in the left lower limb from last one year, which the patient had neglected. Therefore, the patient was diagnosed as space occupying lesion brain. During surgery, a purplish‑red tumor was observed in the brain. Intraoperative crush cytology was asked for. JMS 2017;20(2):108

scholarly journals Recurrent Malignant Fibrous Histiocytoma in the Left Parietal Region of Cranium: A Case Report

1970 ◽  
Vol 17 (1) ◽  
pp. 55-56
Author(s):  
ML Rahman ◽  
ASM Shawkat Ali
Keyword(s):  
Malignant Fibrous Histiocytoma ◽  
Fibrous Histiocytoma ◽  
Brain Parenchyma ◽  
Parietal Region ◽  
Skull Bone ◽  
Previous Surgery ◽  
History Of ◽  
One Year ◽  
The Brain ◽  
Space Occupying Lesion

A male of 20 years of age presented with features of intracranial space occupying lesion of cranium involving the brain. He came with the history of previous surgery in the head one-year back. On operation, an osteolytic growth from the skull bone invading the meninges and brain parenchyma. Who found Histopathological report revealed malignant fibrous histiocytoma.   doi: 10.3329/taj.v17i1.3492 TAJ 2004; 17(1) : 55-56

scholarly journals Corpus callosum infarction: a case report

2020 ◽  
Vol 7 (11) ◽  
pp. 1751
Author(s):  
Ziyad Almushayti
Keyword(s):  
Magnetic Resonance Imaging ◽  
Corpus Callosum ◽  
Lower Limb ◽  
Case Reports ◽  
Resonance Imaging ◽  
Limb Weakness ◽  
Lower Limb Weakness ◽  
Left Lower Limb ◽  
History Of ◽  
Artery Disease

Infarctions of corpus callosal are rare due to an abundant collateral blood supply. Few case reports published in the literature regarding the corpus callosum infarction. We present a case of corpus callosum infarction in a 66-year-old man with a history of diabetes mellitus, hypertension, and coronary artery disease who presented to the emergency room with left lower limb weakness. Diagnosed was made based on magnetic resonance imaging and treated conservatively.  

scholarly journals Neurologic melioidosis presented as encephalomyelitis and subdural collection in two male labourers in India

2015 ◽  
Vol 9 (11) ◽  
pp. 1289-1293 ◽  
Author(s):  
Kavitha Saravu ◽  
Rajagopal Kadavigere ◽  
Ananthakrishna Barkur Shastry ◽  
Rohit Pai ◽  
Chiranjay Mukhopadhyay
Keyword(s):  
Lower Limb ◽  
Corticosteroid Treatment ◽  
Conus Medullaris ◽  
Subdural Empyema ◽  
Lower Limbs ◽  
High Dose ◽  
Limb Weakness ◽  
Subdural Collection ◽  
Lower Limb Weakness ◽  
Left Lower Limb

Two distinct and potentially deceitful cases of neurologic melioidosis are reported. Case 1: A 39-year-old alcoholic and uncontrolled diabetic male presented with cough, fever, and left focal seizures with secondary generalization. An magnetic resonance imaging (MRI) brain scan revealed a small peripherally enhancing subdural collection along the interhemispheric fissure suggestive of minimal subdural empyema. Blood culture grew Burkholderia pseudomallei. Patient was diagnosed with disseminated bacteraemic melioidosis with subdural empyema. He was successfully treated with ceftazidime-cotrimoxazole-doxycycline. Case 2: A 45-year-old male presented with left lower limb weakness, difficulty in passing urine and stool, and back pain radiating to lower limbs. Neurological examination revealed flaccid left lower limb with absent deep tendon reflexes and plantar reflex. Spinal MRI showed T2 hyperintensity from D9 to L1 suggestive of demyelination. Patient was treated with high dose methylprednisolone. By day 3 of steroid treatment, lower limb weakness progressed. Subsequent MRI showed extensive cord hyperintensity on T2 weighted sequence extending from C5 to conus medullaris consistent with demyelination. Cerebrospinal fluid (CSF) culture grew B. pseudomallei, and the patient was given meropenem-cotrimoxazole. After three weeks of parenteral treatment, the lower limbs remained paralyzed. Patient was discharged on oral cotrimoxazole-doxycycline. Conclusions: Melioidosis should be considered as a differential in focal suppurative central nervous system (CNS) lesions, meningoencephalitis, or encephalomyelitis in endemic areas. CNS infections must be ruled out prior to steroid administration. The role of corticosteroids in demyelinating CNS melioidosis has been refuted. This is a rare documentation of effect of unintentional corticosteroid treatment in melioidosis.

Lymphoedema praecox in a young woman: a rare disease

2021 ◽  
Vol 14 (9) ◽  
pp. e245353
Author(s):  
Sri Hari Priya Vemulakonda ◽  
Naveen Kumar Gaur ◽  
Oseen Hajilal Shaikh ◽  
Uday Shamrao Kumbhar
Keyword(s):  
Rare Disease ◽  
Young Woman ◽  
Lower Limb ◽  
Young Age ◽  
Rare Disorder ◽  
Imaging Studies ◽  
Left Lower Limb ◽  
History Of

Primary lymphoedema is a rare disorder. Often presents at a young age with asymptomatic limb oedema with gradual progression. We present a 16-year-old woman who presented with a history of swelling of the left lower limb for 6 years. There was the presence of isolated left lower limb oedema, which was a non-pitting type. The patient underwent imaging studies and was diagnosed to have primary lymphoedema. The patient was managed conservatively as the patient did not have any other problems other than the left lower limb oedema.

A craniopharyngioma in a seven-year-old dog

1991 ◽  
Vol 62 (2) ◽  
pp. 65-67 ◽  
Author(s):  
G. N. Eckersley ◽  
Judith K. Geel ◽  
N. P.J. Kriek
Keyword(s):  
Cerebrospinal Fluid ◽  
Clinical Investigation ◽  
Sinus Bradycardia ◽  
Post Mortem ◽  
Axial Tomography ◽  
History Of ◽  
Computerised Axial Tomography ◽  
The Brain ◽  
Tomography Scan ◽  
Space Occupying Lesion

A seven-year-old male Border Collie was presented with a history of lethargy, episodic circling, incoordination and polydypsia. Physical examination revealed depression, obesity and bradycardia. A neurological examination indicated the possible presence of a space-occupying lesion in the brain. Results of the clinical investigation revealed hyposthenuria, sinus bradycardia and increased concentration of protein in the cerebrospinal fluid. A computerised axial tomography scan revealed a mass in the region of the hypophysis. The dog was euthanased and a post mortem examination confirmed the presence of a craniopharyngioma.

THUR 007 A garden variety neuropathy

2018 ◽  
Vol 89 (10) ◽  
pp. A2.2-A2
Author(s):  
Salini Sumangala ◽  
Ben Simpson ◽  
Jithin George
Keyword(s):  
Lower Limb ◽  
Northern Europe ◽  
Suspected Case ◽  
Structural Imaging ◽  
Facial Weakness ◽  
Rapid Improvement ◽  
Limb Weakness ◽  
Lower Limb Weakness ◽  
Uncertain Significance ◽  
The Brain

A 47 year old with subacute onset of walking difficulties, asymmetric lower limb and facial weakness and areflexia was admitted as a suspected case of Guillain-Barre syndrome. Clinical examination revealed left lower motor neuron facial weakness, right upper limb and lower limb weakness and a suspended area of pain and allodynia at T7. Structural imaging of the brain and spine was normal. CSF protein was elevated with pleocytosis. Nerve conduction studies was suggestive of proximal demyelinating polyradicular neuropathy. The clinical suspicion of neuroborreliosis was confirmed in CSF with Borrelia VlsE antigen positivity and serum Borrelia Burgdorferi IgG EIA positivity. The patient had no recollection of tick exposure but did recall a presumed horsefly bite on the forearm two weeks earlier of uncertain significance. This is a case of Bannwarth syndrome - meningoradiculoneuritis due to neuroborreliosis endemic in Northern Europe. Our patient was treated with Ceftriaxone with rapid improvement of symptoms. This case highlights the importance of careful history taking including ascertainment of travel to Borrelia endemic areas and recognition of this eminently treatable meningoradiculoneuropathy.

scholarly journals Successful Treatment of Lower Limb Complex Regional Pain Syndrome following Three Weeks of Hyperbaric Oxygen Therapy

2016 ◽  
Vol 2016 ◽  
pp. 1-4 ◽  
Author(s):  
Rita Katznelson ◽  
Shira C. Segal ◽  
Hance Clarke
Keyword(s):  
Complex Regional Pain Syndrome ◽  
Hyperbaric Oxygen ◽  
Lower Limb ◽  
Hyperbaric Oxygen Therapy ◽  
Skin Color ◽  
Oxygen Therapy ◽  
Pain Syndrome ◽  
Animal Pain ◽  
History Of ◽  
One Year

Hyperbaric oxygen therapy (HBOT) is a treatment that delivers 100% oxygen at increased atmospheric pressures. The efficacy of HBOT for treating pain has been described in various animal pain models and may have clinical efficacy in the treatment of human chronic pain syndromes. We present our experience with posttraumatic Complex Regional Pain Syndrome (CRPS) type 2 in a patient who underwent 15 sessions of HBOT. A 41-year-old male with one-year history of CRPS of left foot followed by left ankle fracture demonstrated less pain, decreased swelling, less allodynia, and improvement in skin color and range of motion of the lower limb after 3 weeks of HBOT. Patient was back to work for the first time in over a year. HBOT may be considered as a valuable therapeutic tool in the treatment of long-standing CRPS.

scholarly journals Multiple CNS Tumors in a Patient With Neurofibromatosis Type 2: Classical Presentation of a Rare Disease

2020 ◽  
Author(s):  
Aamer Ubaid ◽  
Farishta Waheed ◽  
Awais Naeem
Keyword(s):  
Rare Disease ◽  
Lower Limb ◽  
Neurofibromatosis Type ◽  
Neurofibromatosis Type 2 ◽  
Lumbar Region ◽  
Nerve Paralysis ◽  
Function Tests ◽  
Left Lower Limb ◽  
History Of

Neurofibromatosis type 2 is a genetic autosomal dominant disorder caused by a spontaneous mutation in the gene located on chromosome 22 q11-13.1, which usually emerges in adolescence or early adulthood and is characterized by the development of bilateral vestibular schwannoma. We hereby report the classical case of Neurofibromatosis type 2 in a 25-year-old young male with multiple tumors associated with the disease. This patient presented to us with 3 years history of multiple painless nodules on his skin, facial weakness, left-sided progressive hearing loss, and 20 days history of weakness in the left lower limb. On Examination, he was vital with a GCS of 15/15. He was anemic with no jaundice. He had left inguinal lymphadenopathy along with multiple subcutaneous nodules on different areas, including the scalp, face, left mid-axillary line over the abdomen. He also had Right-sided facial palsy and horizontal nystagmus. CNS examination revealed an upgoing plantar on the left side, right facial nerve palsy, and bilateral vestibulocochlear nerve paralysis. Spine examination revealed spinal tenderness in the lower lumbar region. Superficial abdominal reflexes were absent. Upper limb and right lower limb power, tone, and reflexes were normal while the tone and power in the left lower limb were reduced power being ⅗. Reflexes were also exaggerated in the left lower limb. The right ankle showed swelling, most probably a plexiform neuroma. On investigations, he had normochromic normocytic anemia with mild leucocytosis. Platelets were normal. The rest of the biochemical investigations, including serum electrolytes, liver function tests, and renal function tests, were also normal.MRI brain and spine confirmed bilateral acoustic neuroma and multiple cranial and peripheral nerve tumors i.e., classical presentation of a rare disease neurofibromatosis. He was referred to the neurology unit for further assessment and treatment.

scholarly journals Hypokalaemic paralysis and metabolic alkalosis in a patient with Sjögren syndrome: a case report and literature review

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Rasika Ranaweerage ◽  
Shehan Perera ◽  
Aruna Gunapala
Keyword(s):  
Lower Limb ◽  
Metabolic Alkalosis ◽  
Muscle Power ◽  
Autoimmune Disorders ◽  
Sjögren Syndrome ◽  
Gitelman Syndrome ◽  
Sjogren Syndrome ◽  
Limb Weakness ◽  
Primary Sjögren Syndrome ◽  
History Of

Abstract Background Acquired Gitelman syndrome is a very rare disorder reported in association with autoimmune disorders, mostly Sjögren syndrome. It is characterized by the presence of hypokalaemic metabolic alkalosis, hypocalciuria, hypomagnesaemia and hyper-reninaemia, in the absence of typical genetic mutations associated with inherited Gitelman syndrome. Case presentation A 20 year old woman who was previously diagnosed with primary Sjögren syndrome and autoimmune thyroiditis presented with two week history of lower limb weakness and salt craving. Examination revealed upper limb and lower limb muscle weakness with muscle power of 3/5 on MRC scale and diminished deep tendon reflexes. On evaluation, she had hypokalaemia with high trans-tubular potassium gradient, metabolic alkalosis and hypocalciuria, features suggestive of Gitelman syndrome. New onset hypokalaemic alkalosis in a previously normokalaemic patient with Sjögren syndrome strongly favored a diagnosis of acquired Gitelman syndrome. Daily potassium supplementation and spironolactone resulted in complete clinical recovery. Conclusions Acquired Gitelman syndrome associated with Sjögren syndrome is rare. It should be considered as a differential diagnosis during evaluation of acute paralysis and hypokalaemic metabolic alkalosis in patients with autoimmune disorders, especially Sjögren syndrome.

Successful treatment of disseminated granulomatous aspergillosis in an apparently immunocompetent host

2020 ◽  
Vol 50 (4) ◽  
pp. 346-349 ◽  
Author(s):  
Umang Agrawal ◽  
Pratik Savaj ◽  
Kanishka Davda ◽  
Rajeev Soman ◽  
Anjali Shetty ◽  
...  
Keyword(s):  
Granulomatous Inflammation ◽  
Surgical Excision ◽  
Immunocompetent Host ◽  
Short History ◽  
Normal Individuals ◽  
History Of ◽  
One Year ◽  
Work Up ◽  
The Brain

A young Indian man presented elsewhere with a short history of haematuria and cough. Investigations revealed renal and pulmonary lesions. Histopathology of these lesions was reported as mucormycosis. He consulted us two months after onset of symptoms, asymptomatic and clinically well, having received no treatment. In view of clinico-histopathological discordance, a review of the biopsy slides was advised but the patient refused further work-up at that time. One week later, however, he was admitted with left hemiparesis. Brain imaging showed an abscess. He underwent surgical excision of the brain abscess and nephrectomy. Review of previous slides showed septate fungal filaments with granulomatous inflammation. Intraoperative cultures grew Aspergillus flavus. He received voriconazole for one year and is well at his two-year follow-up. His immunological work-up was negative for immunodeficiency. This case illustrates that granulomatous aspergillosis may be an indolent infection in apparently normal individuals and reiterates the importance of interpreting diagnostic reports in conjunction with clinical features.

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