scholarly journals Complete cessation of epileptiform events caused by benign epilepsy with centrotemporal spikes (BECTS) in 9-year-old male

2019 ◽  
Vol 10 ◽  
Author(s):  
Shannon Leon ◽  
Jason Langhough
1972 ◽  
Vol 70 (1) ◽  
pp. 167-174 ◽  
Author(s):  
Artur Ber

ABSTRACT Hypophysectomy was performed at the same time as ovariectomy in 19 rats aged 6 weeks; in addition a fragment of the animal's own ovary was implanted into the greater omentum. The graft took but there was complete cessation of the growth of the implant and a decrease in body and uterine weights as compared to 15 ovariectomized controls of the same age killed after one month. This shows that the pituitary is indispensable for the growth of ovarian implants but not for their take. In 84 spayed rats aged 3 weeks with ovarian implants, methallibure (6 mg/day in a 0.2% solution of Tween 20) was given by gavage during one month. Some of them were treated with PMSG (20 IU/day), HCG (20 IU/day) or with oestradiol benzoate (0.05 mg/day) only or in combinations. As controls, there were 74 spayed rats with ovarian implants, seven of which received Tween 20, and 67 were untreated. No differences were found between the two control groups. Methallibure alone caused arrest of the development of the implants and uteri and a decrease in body weight. In the methallibure treated animals HCG stimulated the growth of the implant which was, however, smaller than that in the controls, while PMSG restored the weight of the implant even above that of the control rats. Oestradiol benzoate caused a further diminution in the size of the implants but augmented considerably the influence of HCG on the implants. It had no effect on the weight of the implant in rats treated with PMSG. It is concluded that FSH is the principal implant growth-promoting factor and that oestrogens appear to act in two directions. They decrease the gonadotrophin output from the pituitary thus inhibiting the growth of the implants, but in the presence of gonadotrophins they act directly on the implants, promoting their development.


2021 ◽  
Vol 11 (15) ◽  
pp. 6983
Author(s):  
Maritza Mera-Gaona ◽  
Diego M. López ◽  
Rubiel Vargas-Canas

Identifying relevant data to support the automatic analysis of electroencephalograms (EEG) has become a challenge. Although there are many proposals to support the diagnosis of neurological pathologies, the current challenge is to improve the reliability of the tools to classify or detect abnormalities. In this study, we used an ensemble feature selection approach to integrate the advantages of several feature selection algorithms to improve the identification of the characteristics with high power of differentiation in the classification of normal and abnormal EEG signals. Discrimination was evaluated using several classifiers, i.e., decision tree, logistic regression, random forest, and Support Vecctor Machine (SVM); furthermore, performance was assessed by accuracy, specificity, and sensitivity metrics. The evaluation results showed that Ensemble Feature Selection (EFS) is a helpful tool to select relevant features from the EEGs. Thus, the stability calculated for the EFS method proposed was almost perfect in most of the cases evaluated. Moreover, the assessed classifiers evidenced that the models improved in performance when trained with the EFS approach’s features. In addition, the classifier of epileptiform events built using the features selected by the EFS method achieved an accuracy, sensitivity, and specificity of 97.64%, 96.78%, and 97.95%, respectively; finally, the stability of the EFS method evidenced a reliable subset of relevant features. Moreover, the accuracy, sensitivity, and specificity of the EEG detector are equal to or greater than the values reported in the literature.


2019 ◽  
Vol 15 (2) ◽  
pp. 211
Author(s):  
Hyun-Soo Choi ◽  
Yoon Gi Chung ◽  
Sun Ah Choi ◽  
Soyeon Ahn ◽  
Hunmin Kim ◽  
...  

2009 ◽  
Vol 25 (1) ◽  
pp. 127-128 ◽  
Author(s):  
Thierry Deonna ◽  
Eliane Roulet-Perez ◽  
Stephany Cronel-Ohayon ◽  
Claire Mayor-Dubois

2005 ◽  
Vol 113 (7) ◽  
pp. 939-949 ◽  
Author(s):  
A. Liasis ◽  
D. E. Bamiou ◽  
S. Boyd ◽  
A. Towell
Keyword(s):  

PEDIATRICS ◽  
1988 ◽  
Vol 81 (5) ◽  
pp. 746-746
Author(s):  
P. A.D. BOUMA ◽  
A. C.B. PETERS

To the Editor.— Is there a group of children whose seizures have an excellent prognosis without any treatment whatsoever? The recent article by Freeman et al1 clearly favors a positive answer. They suggest that children who are likely to remain seizure free when medication is discontinued after 2 years without seizures2 might be good candidates for withholding any treatment. Our findings3 may support this suggestion. Anticonvulsant medication was stopped in a prospective study in 116 children with epilepsy (defined as two afebrile seizures or more) who had had no seizures for 2 years.


2007 ◽  
Vol 36 (3) ◽  
pp. 141-145 ◽  
Author(s):  
Anita Datta ◽  
D. Barry Sinclair
Keyword(s):  

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