Publication Trends on Mitophagy in the World and China: A 16-Year Bibliometric Analysis

In the past 16 years, research on mitophagy has increasingly expanded to a wider range of subjects. Therefore, comprehensively analyzing the relevant progress and development trends on mitophagy research requires specific methods. To assess the hotspots, directions, and quality of results in this field worldwide, we used multiple tools to examine research progress and growing trends in research on the matter during the last 16 years (from 2005 to 2020). We also compared the quantity and quality of the literature records on mitophagy published by research institutions in China and other developed countries, reviewed China’s contribution, and examined the gap between China and these developed countries. According to the results of our bibliometric analysis, the United States and its research institutes published the most papers. We identified cell biology as the most commonly researched subject on mitophagy and AUTOPHAGY as the most popular journal for research on mitophagy. We also listed the most cited documents from around the world and China. With gradually increased funding, China is progressively becoming prominent in the field of mitophagy; nevertheless, the gap between her and major countries in the world must be closed.

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A Bibliometric Analysis of Researches on Flap Endonuclease 1 From 2005 to 2019

10.21203/rs.3.rs-136655/v1 ◽

2021 ◽

Author(s):

Qiaochu Wei ◽

Jiming Shen ◽

Dongni Wang ◽

Xu Han ◽

Jing Shi ◽

...

Keyword(s):

Bibliometric Analysis ◽

Protein Interactions ◽

Cell Biology ◽

Biological Activities ◽

The United States ◽

Dna Metabolism ◽

Flap Endonuclease 1 ◽

The Past ◽

Oncology Research ◽

Research Frontiers

Abstract Background: Flap endonuclease 1 (FEN1) is a structure-specific nuclease that plays a role in a variety of DNA metabolism processes. FEN1 is important for maintaining genomic stability and regulating cell growth and development. It is associated with the occurrence and development of several diseases, especially cancers. There is a lack of systematic bibliometric analyses focusing on research trends and knowledge structures related to FEN1.Purpose: To analyze hotspots, the current state and research frontiers performed for FEN1 over the past 15 years. Methods: Publications were retrieved from the Web of Science Core Collection (WoSCC) database, analyzing publication dates ranging from 2005 to 2019. VOSviewer1.6.15 and Citespace5.7 R1 were used to perform a bibliometric analysis in terms of countries, institutions, authors, journals and research areas related to FEN1. A total of 421 publications were included in this analysis. Results: Our findings indicated that FEN1 has received more attention and interest from researchers in the past 15 years. Institutes in the United States, specifically the Beckman Research Institute of City of Hope published the most research related to FEN1. SHEN BH，ZHENG L and BAMBARA RA were the most active researchers investigating this endonuclease and most of this research was published in the Journal of Biological Chemistry. The main scientific areas of FEN1 were related to biochemistry, molecular biology，cell biology，genetics and oncology. Research hotspots included biological activities, DNA metabolism mechanisms, protein-protein interactions and gene mutations. Research frontiers included oxidative stress, phosphorylation and tumor progression and treatment. Conclusion: This bibliometric study may aid researchers in the understanding of the knowledge base and research frontiers associated with FEN1. In addition, emerging hotspots for research can be used as the subjects of future studies.

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A bibliometric analysis of researches on flap endonuclease 1 from 2005 to 2019

BMC Cancer ◽

10.1186/s12885-021-08101-2 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Qiaochu Wei ◽

Jiming Shen ◽

Dongni Wang ◽

Xu Han ◽

Jing Shi ◽

...

Keyword(s):

Bibliometric Analysis ◽

Protein Interactions ◽

Cell Biology ◽

Biological Activities ◽

The United States ◽

Dna Metabolism ◽

Flap Endonuclease 1 ◽

The Past ◽

Oncology Research ◽

Research Frontiers

Abstract Background Flap endonuclease 1 (FEN1) is a structure-specific nuclease that plays a role in a variety of DNA metabolism processes. FEN1 is important for maintaining genomic stability and regulating cell growth and development. It is associated with the occurrence and development of several diseases, especially cancers. There is a lack of systematic bibliometric analyses focusing on research trends and knowledge structures related to FEN1. Purpose To analyze hotspots, the current state and research frontiers performed for FEN1 over the past 15 years. Methods Publications were retrieved from the Web of Science Core Collection (WoSCC) database, analyzing publication dates ranging from 2005 to 2019. VOSviewer1.6.15 and Citespace5.7 R1 were used to perform a bibliometric analysis in terms of countries, institutions, authors, journals and research areas related to FEN1. A total of 421 publications were included in this analysis. Results Our findings indicated that FEN1 has received more attention and interest from researchers in the past 15 years. Institutes in the United States, specifically the Beckman Research Institute of City of Hope published the most research related to FEN1. Shen BH, Zheng L and Bambara Ra were the most active researchers investigating this endonuclease and most of this research was published in the Journal of Biological Chemistry. The main scientific areas of FEN1 were related to biochemistry, molecular biology, cell biology, genetics and oncology. Research hotspots included biological activities, DNA metabolism mechanisms, protein-protein interactions and gene mutations. Research frontiers included oxidative stress, phosphorylation and tumor progression and treatment. Conclusion This bibliometric study may aid researchers in the understanding of the knowledge base and research frontiers associated with FEN1. In addition, emerging hotspots for research can be used as the subjects of future studies.

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Interweaving Industrial Ecology and Ecological Modernization: A Comparative Bibliometric Analysis

Sustainability ◽

10.3390/su13179673 ◽

2021 ◽

Vol 13 (17) ◽

pp. 9673

Author(s):

Feng Han ◽

Zhangcong Feng ◽

Chao Wang ◽

Nujie Yang ◽

Dong Yang ◽

...

Keyword(s):

Bibliometric Analysis ◽

Industrial Development ◽

Industrial Ecology ◽

Resource Constraints ◽

Policy Design ◽

Developed Countries ◽

The United States ◽

Future Research ◽

Ecological Modernization ◽

The Past

Although industrial activity has brought about rapid economic growth, it also faces the dual challenges of resource constraints and environmental pressure. Industrial ecology (IE) and ecological modernization (EM) are two theories regarding the conceptualization and implementation of sustainable development that emerged from the natural and social sciences, respectively. Over the past three decades, scholars have conducted copious amounts of theoretical and applied research on IE and EM, but comparative studies from an interdisciplinary perspective on the relationship between the two remain relatively rare. On the basis of a bibliometric analysis, this study offers a comprehensive examination of the background, theoretical connotations, and main content of IE and EM, also exploring the role of both theoretical perspectives in the promotion of sustainable industrial development. The findings are fourfold: (1) the research on IE and EM has been increasing year by year, particularly in the past decade; (2) the research is mostly concentrated in developed countries such as the United States and European Union member nations, and contributions from China have increased significantly in recent years; (3) IE has a broader research community than EM and has evolved clearer and more specific research contents and methods; and (4) IE, which analyzes the problems of specific industrial systems, and EM, which constitutes a higher-level institutional policy design, exhibit a trend of cross-fertilization. This study provides a reference for building a more systematic and comprehensive theoretical system of ecological transformation and discusses the future research directions in this field.

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A Worldwide Bibliometric Analysis of Publications on Advance Care Planning in the Past 3 Decades

American Journal of Hospice and Palliative Medicine® ◽

10.1177/1049909119886305 ◽

2019 ◽

Vol 37 (6) ◽

pp. 474-480

Author(s):

Chia-Jen Liu ◽

Te-Chun Yeh ◽

Ming-Hsuan Hsieh ◽

Lin-Chung Woung ◽

Sheng-Jean Huang ◽

...

Keyword(s):

United States ◽

End Of Life ◽

Bibliometric Analysis ◽

Advance Care Planning ◽

Developed Countries ◽

The United States ◽

Research Field ◽

Care Planning ◽

The Past ◽

Advance Care

Background: In recent decades, issues related to end-of-life care and advance care planning (ACP) have attracted popular attention. Advance care planning has been broadly discussed as one of the potential solutions to protect a patient’s rights, autonomy, and dignity at the end of life. To better understand publishing on this topic, we conducted this study to demonstrate the worldwide research productivity, trends, and citations of ACP in the past 3 decades by bibliometric analysis. Methods: Articles published on ACP were retrieved from the Web of Science Core Collection database, and the subject terms included “advance directive,” or “advance care planning.” Results: Overall, 2126 publications on ACP were retrieved until January 22, 2019. North America, Western Europe, and Australia were the most productive regions. The top 15 countries published 95.9% of the total number of articles. The United States accounted for approximately three-fifths (61.0%) of all publications. When adjusted for population size, Australia had the highest number of articles per million persons (6.64), followed by the Netherlands (6.14) and Belgium (4.61). The most productive authors were Sudore (n = 37), Deliens (n = 29), and Green (n = 24). Conclusions: The current study revealed that research in terms of publications on ACP has rapidly increased over the past 3 decades. Developed countries, especially the United States, were more concerned with the ACP research field than developing countries were.

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Global trends of researches on pycho-oncology during 1999-2019: A 21-year bibliometric study based on VOSviewer

10.21203/rs.3.rs-22565/v1 ◽

2020 ◽

Author(s):

Chengjiao Zhang ◽

Guangfu Hu ◽

Xiaochun Qiu ◽

Lingyi Pan ◽

Cheng Wang

Keyword(s):

Breast Cancer ◽

Quality Of Life ◽

New York ◽

Bibliometric Analysis ◽

Developed Countries ◽

The United States ◽

University Hospital ◽

Screening Process ◽

Author Keywords

Abstract BackgroundThe studies on psycho-oncology are growing rapidly, but there were no bibliometric studies regarding psycho-oncology. This study was to explore a bibliometric analysis of psycho-oncology in the past 21 years at a global level.MethodsThe literature was searched in Web of Science (WOS) by using subject terms. VOSviewer software was used for bibliometric analysis of the retrieval results.ResultsThe literature search yielded 1921 papers. After screening process, 968 papers were included, which came from 55 countries/regions, 1,452 organizations and 4,152 authors. The top three countries/regions, organizations and authors ranked by the number of published papers were the United States of America (USA) (286), Germany (143) and Australia (130); the Memorial Sloan-Kettering Cancer Centre (MSKCC) (New York, USA) (34), Newcastle University (Newcastle, Australia) (29) and McGill University (Montreal, Canada) (28); Luigi Grassi (University of Ferrara in Italy) (26), Tatsuo Akechi (Nagoya City University Hospital in Japan) (20) and Anja Mehnert (University of Leipzig in Germany) (18), respectively. Moreover, the 968 papers contained 1,768 author keywords, involved in 300 journals and cited 28,311 references. The top three co-occurrence author keywords, most-involved journals and most-cited references were “Quality-of-life”, “Depression” and “Breast cancer”; Psycho-Oncology, Supportive Care in Cancer and Journal of Psychosocial Oncology; “Zigmond AS, 1983”, “Zabora J, 2001” and “Mitchell AJ, 2011”, respectively.ConclusionsThere was a growing trend in published papers related to psycho-oncology, with the organizations and authors from developed countries leading the field. “Quality-of-life”, “Depression” and “Breast cancer” reflected the most hotspots, and the latest progress can be tracked in Psycho-Oncology.

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Research Progress of Coronavirus Based on Bibliometric Analysis

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph17113766 ◽

2020 ◽

Vol 17 (11) ◽

pp. 3766 ◽

Cited By ~ 9

Author(s):

Fei Zhai ◽

Yuxuan Zhai ◽

Chuang Cong ◽

Tingyan Song ◽

Rongwu Xiang ◽

...

Keyword(s):

International Cooperation ◽

Bibliometric Analysis ◽

Core Collection ◽

Web Of Science ◽

The United States ◽

Research Progress ◽

Research Directions ◽

The Past ◽

Funding Support ◽

The Web

Background: COVID-19 has become one of the most serious global epidemics in the 21st Century. This study aims to explore the distribution of research capabilities of countries, institutions, and researchers, and the hotspots and frontiers of coronavirus research in the past two decades. In it, references for funding support of urgent projects and international cooperation among research institutions are provided. Method: the Web of Science core collection database was used to retrieve the documents related to coronavirus published from 2003 to 2020. Citespace.5.6.R2, VOSviewer1.6.12, and Excel 2016 were used for bibliometric analysis. Results: 11,036 documents were retrieved, of which China and the United States have contributed the most coronavirus studies, Hong Kong University being the top contributor. Regarding journals, the Journal of Virology has contributed the most, while in terms of researchers, Yuen Kwok Yung has made the most contributions. The proportion of documents published by international cooperation has been rising for decades. Vaccines for SARS-CoV-2 are under development, and clinical trials of several drugs are ongoing. Conclusions: international cooperation is an important way to accelerate research progress and achieve success. Developing corresponding vaccines and drugs are the current hotspots and research directions.

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The Contribution of American Nurses to the Evolution of the International Council of Nurses

OJIN: The Online Journal of Issues in Nursing ◽

10.3912/ojin.vol25no02man05 ◽

2020 ◽

Vol 25 (2) ◽

Author(s):

Stephanie Ferguson ◽

David Benton

Keyword(s):

Services Quality ◽

The United States ◽

Nursing Profession ◽

Collaborative Effort ◽

Access To Services ◽

International Council ◽

The Past ◽

Wide Range ◽

The World

As the nursing profession celebrates the International Year of the Nurse and Midwife, it is time to take stock of the contribution that American nurses and the United States have made to the evolution of the International Council of Nurses (ICN). American nurses were involved even before the conception of the organization and have played a significant role in its leadership and development. Nurses who have been active in the American Nurses Association (ANA) have often been heavily involved in various aspects of ICN governance and evolution. Additionally, several American philanthropic foundations and corporate donors have supported a wide range of ICN activity that has helped advance the nursing profession around the world. As we celebrate Nightingale’s legacy, we should also think about all the nurses who have brought us to this point from the past, and those collaborating today and tomorrow. Examining the contribution of American nursing highlights the fact that this collaborative effort of the world’s nurses is needed if we are to optimize access to services, quality of care and sustainability of the nursing profession.

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The Quest for a Better World

Mechanical Engineering ◽

10.1115/1.2000-dec-2 ◽

2000 ◽

Vol 122 (12) ◽

pp. 46-51

Author(s):

Henry Petroski

Keyword(s):

Air Conditioning ◽

Technological Progress ◽

Developed Countries ◽

Past Century ◽

Open Problems ◽

The Past ◽

The World ◽

The Developed Countries ◽

Made In

This article highlights the pervasiveness of the products and processes of engineering in having improved the quality of life in the developed countries of the world. The airplane and its associated infrastructure of airports and ticketing schemes have come a long way since the Wright Brothers’ first flight in 1903, and the ensemble that goes under the rubric ‘airplane’ certainly warrants recognition as achievement. All the engineering achievements that have been identified as among the greatest of the past century leave room for improvement. Air conditioning and refrigeration are among the more domestic achievements of 20th century engineering, but at exactly what stage they became so is hard to say. Refrigerators especially came a long way in the second half of the century. Well-controlled air conditioning, for all the technological progress made in the field since air was fanned over a block of ice, seems to remain one of the great open problems of mechanical engineering. All achievements, engineering and otherwise, are relative to their time and circumstances.

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Remaking Retirement

10.1093/oso/9780198867524.001.0001 ◽

2020 ◽

Keyword(s):

Interest Rates ◽

Older Workers ◽

Older Persons ◽

The United States ◽

Older Population ◽

The Past ◽

Cost Of Education ◽

The World ◽

Low Interest Rates ◽

Key Aspects

Around the world, people nearing and entering retirement are holding ever-greater levels of debt than in the past. This is not a benign situation, as many pre-retirees and retirees are stressed about their indebtedness. Moreover, this growth in debt among the older population may render retirees vulnerable to financial shocks, medical care bills, and changes in interest rates. Contributors to this volume explore key aspects of the rise in debt across older cohorts, drill down into the types of debt and reasons for debt incurred by the older population, and review policies to remedy some of the financial problems facing older persons, in the United States and elsewhere. The authors explore which groups are most affected by debt, and they also identify the factors causing this important increase in leverage at older ages. It is clear that the economic and market environments are influential when it comes to saving and debt. Access to easy borrowing, low interest rates, and the rising cost of education have had important impacts on how much people borrow, and how much debt they carry at older ages. In this environment, the capacity to manage debt is ever more important as older workers lack the opportunity to recover for mistakes.

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Global publication trends and hotspots of molecular biomarkers in DILI from 1991 to 2020: A 30-year bibliometric analysis

Science Progress ◽

10.1177/00368504211000535 ◽

2021 ◽

Vol 104 (1) ◽

pp. 003685042110005

Author(s):

Mingnan Cao ◽

Li Wang ◽

Lin Zhang ◽

Jingli Duan

Keyword(s):

Bibliometric Analysis ◽

Research Collaboration ◽

Citation Networks ◽

Publication Trends ◽

Drug Induced ◽

Topic Area ◽

The Past ◽

Black Box Warnings ◽

The Usa ◽

Post Marketing

Drug-induced liver injury (DILI) is one of the common adverse drug reactions and the leading cause of drug development attritions, black box warnings, and post-marketing withdrawals. Current biomarkers are suboptimal in detecting DILI and predicting its outcome. This study aimed to quantitatively and qualitatively investigate the research trends on DILI biomarkers using bibliometric analysis. All relevant publications were extracted from the Web of Science database. An online analysis platform of literature metrology, bibliographic item co-occurrence matrix builder, and CiteSpace software were used to analyze the publication trends. CitNetExplorer was used to construct direct citation networks and VOSviewer was used to analyze the keywords and research hotspots. We found a total of 485 publications related to DILI biomarkers published from 1991 to 2020. Toxicological Sciences had been the most popular journal in this field over the past 30 years. The USA maintained a top position worldwide and provided a pivotal influence, followed by China. Among all the institutions, the University of Liverpool was regarded as a leader for research collaboration. Moreover, Professors Paul B. Watkins and Tsuyoshi Yokoi made great achievements in topic area. We analyzed the citation networks and keywords, therefore identified five and six research hotspot clusters, respectively. We considered the publication information regarding different countries/regions, organizations, authors, journals, et al. by summarizing the literature on DILI biomarkers over the past 30 years. Notably, the subject of DILI biomarkers is an active area of research. In addition, the investigation and discovery of novel promising biomarkers such as microRNAs, keratin18, and bile acids will be future developing hotspots.

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