scholarly journals Global publication trends and hotspots of molecular biomarkers in DILI from 1991 to 2020: A 30-year bibliometric analysis

2021 ◽  
Vol 104 (1) ◽  
pp. 003685042110005
Author(s):  
Mingnan Cao ◽  
Li Wang ◽  
Lin Zhang ◽  
Jingli Duan

Drug-induced liver injury (DILI) is one of the common adverse drug reactions and the leading cause of drug development attritions, black box warnings, and post-marketing withdrawals. Current biomarkers are suboptimal in detecting DILI and predicting its outcome. This study aimed to quantitatively and qualitatively investigate the research trends on DILI biomarkers using bibliometric analysis. All relevant publications were extracted from the Web of Science database. An online analysis platform of literature metrology, bibliographic item co-occurrence matrix builder, and CiteSpace software were used to analyze the publication trends. CitNetExplorer was used to construct direct citation networks and VOSviewer was used to analyze the keywords and research hotspots. We found a total of 485 publications related to DILI biomarkers published from 1991 to 2020. Toxicological Sciences had been the most popular journal in this field over the past 30 years. The USA maintained a top position worldwide and provided a pivotal influence, followed by China. Among all the institutions, the University of Liverpool was regarded as a leader for research collaboration. Moreover, Professors Paul B. Watkins and Tsuyoshi Yokoi made great achievements in topic area. We analyzed the citation networks and keywords, therefore identified five and six research hotspot clusters, respectively. We considered the publication information regarding different countries/regions, organizations, authors, journals, et al. by summarizing the literature on DILI biomarkers over the past 30 years. Notably, the subject of DILI biomarkers is an active area of research. In addition, the investigation and discovery of novel promising biomarkers such as microRNAs, keratin18, and bile acids will be future developing hotspots.

Author(s):  
Jingli Chen ◽  
Xin Li ◽  
Yifan Jia ◽  
Zhongyuan Xia ◽  
Jishi Ye

In the past 16 years, research on mitophagy has increasingly expanded to a wider range of subjects. Therefore, comprehensively analyzing the relevant progress and development trends on mitophagy research requires specific methods. To assess the hotspots, directions, and quality of results in this field worldwide, we used multiple tools to examine research progress and growing trends in research on the matter during the last 16 years (from 2005 to 2020). We also compared the quantity and quality of the literature records on mitophagy published by research institutions in China and other developed countries, reviewed China’s contribution, and examined the gap between China and these developed countries. According to the results of our bibliometric analysis, the United States and its research institutes published the most papers. We identified cell biology as the most commonly researched subject on mitophagy and AUTOPHAGY as the most popular journal for research on mitophagy. We also listed the most cited documents from around the world and China. With gradually increased funding, China is progressively becoming prominent in the field of mitophagy; nevertheless, the gap between her and major countries in the world must be closed.


2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Md Anwarul Islam ◽  
Gunilla Widen

Purpose VINE Journal of Information and Knowledge Management Systems (VJIKMS) is one of the oldest and leading journals in the knowledge management (KM) field. The purpose of this study is to conduct bibliometrics analysis of publications published in VJIKMS for the past two decades. For doing this, this paper covered the past two decades of publications and carried out a science mapping analysis of publications. Design/methodology/approach The methodology included bibliometrics and the science mapping analysis process. This paper imported the bibliographic information of VJIKMS from the abstract and citation database Scopus. Through bibliometrics method, this paper examined the citation results, author productivity, authorship pattern, research collaboration and other parameters of the selected publications. Afterward, this paper used VOSviewer software to carry out the science mapping of bibliometric networks. Findings The findings showed that VJIKMS published 718 publications during 2000–2020, which got cited 4,311 times (6 times per article) till date. Joint authorship and international collaboration have been increasing where 1,417 authors from 66 countries have published. The USA, the UK and Iran lead the KM publications in this journal. Nonaka’s publications and Journal of Knowledge Management (JKM) are highly cited references and journals in the VJIKMS. Research limitations/implications The findings of this study would help the KM students, researchers and practitioners to see the diffusion of KM globally, what are the promising areas to work and helps to know the various patterns of publications if they aim to publish in VJIKMS. Originality/value This is the first time a bibliometric analysis has been conducted to analysis of research publications published in VJIKMS. This presents a comprehensive analysis of publications between 2000 and 2020.


2021 ◽  
Vol 12 ◽  
Author(s):  
Sheng Wang ◽  
Huanping Zhou ◽  
Li Zheng ◽  
Wanli Zhu ◽  
Lina Zhu ◽  
...  

Acute lung injury (ALI) is an intractable disorder associated with macrophages. This bibliometric analysis was applied to identify the characteristics of global scientific output, the hotspots, and frontiers about macrophages in ALI over the past 10 years. We retrieved publications published from 2011 to 2020 and their recorded information from Science Citation Index Expanded (SCI-expanded) of Web of Science Core Collection (WoSCC). Bibliometrix package was used to analyze bibliometric indicators, and the VOSviewer was used to visualize the trend and hotspots of researches on macrophages in ALI. Altogether, 2,632 original articles were reviewed, and the results showed that the annual number of publications (Np) concerning the role of macrophages in ALI kept increasing over the past 10 years. China produced the most papers, the number of citations (Nc) and H-index of the USA ranked first. Shanghai Jiaotong University and INT IMMUNOPHARMACOL were the most prolific affiliation and journal, respectively. Papers published by Matute-Bello G in 2011 had the highest local citation score (LCS). Recently, the keywords “NLRP3” and “extracellular vesicles” appeared most frequently. Besides, researches on COVID-19–induced ALI related to macrophages seemed to be the hotspot recently. This bibliometric study revealed that publications related to macrophages in ALI tend to increase continuously. China was a big producer and the USA was an influential country in this field. Most studies were mainly centered on basic researches in the past decade, and pathways associated with the regulatory role of macrophages in inhibiting and attenuating ALI have become the focus of attention in more recent studies. What is more, our bibliometric analysis showed that macrophages play an important role in COVID-19–induced ALI and may be a target for the treatment of COVID-19.


2019 ◽  
Vol 16 (9) ◽  
pp. 1031-1039
Author(s):  
Peng Zhou ◽  
Minhui Zhu ◽  
Caiyun Zhang ◽  
Donghui Chen ◽  
Hongliang Zheng

Background: There has been increased interest in the research of proteasome inhibitors for more than two decades. Hotspots in this field are constantly changing. Objective: This study aimed to investigate trends in proteasome inhibitors research from 1992 to 2018 and compare the contributions of such research from different countries and authors. Methods: We used Excel 2013 and VoSviewer to analyze bibliometric data on the subject of proteasome inhibitors, including the number of publications, citations frequency, H-index, and country contributions and hotspots (keywords of popular scientific fields). Results: A total of 3646 articles were included. The USA contributed the largest percentage of articles (1742), with the most citations (90666) and the highest H-index (139). The journal Blood had the most articles. Dana Farber Cancer Institute and Millennium Pharmaceuticals Incorporation were the most contributive institutions. Keywords could be divided into three clusters: Basic experiment, clinical research, and others. Conclusion: The number of proteasome inhibitors articles has been increasing for the past 27 years. The USA made the largest contribution in this field. Recent studies on the topic of “carfilzomib” are relatively new and should be closely followed in proteasome inhibitors research.


2021 ◽  
Author(s):  
Ning Li ◽  
Lei Wang ◽  
Yaoda Hu ◽  
Wei Han ◽  
Fuling Zheng ◽  
...  

Aim: To provide a historical and global picture of research concerning lung nodules, compare the contributions of major countries and explore research trends over the past 10 years. Methods: A bibliometric analysis of publications from Scopus (1970–2020) and Web of Science (2011–2020). Results: Publications about pulmonary nodules showed an enormous growth trend from 1970 to 2020. There is a high level of collaboration among the 20 most productive countries and regions, with the USA located at the center of the collaboration network. The keywords ‘deep learning’, ‘artificial intelligence’ and ‘machine learning’ are current hotspots. Conclusions: Abundant research has focused on pulmonary nodules. Deep learning is emerging as a promising tool for lung cancer diagnosis and management.


2020 ◽  
Vol 73 (3) ◽  
pp. 85-94
Author(s):  
Erin E. Soares ◽  
Jillian N. Thrall ◽  
Taylor N. Stephens ◽  
Ricardo Rodriguez Biglieri ◽  
Andrés J. Consoli ◽  
...  

2021 ◽  
Vol 2021 ◽  
pp. 1-11
Author(s):  
Hein Hendrik Smith ◽  
Oladayo Amed Idris ◽  
Mark Steve Maboeta

The fast-growing world population places food production under enormous pressure to ensure food security. One of the most common methods to increase food production is the use of pesticides, but the continuous use thereof has numerous detrimental effects on the environment. The interest in biopesticides for a possible substitute has grown over the past two decades. To determine the research evolution of biopesticides (green pesticides), a bibliometric analysis from 1994 to 2019 was carried out. A total of 580 documents were found eligible in the Scopus database for this analysis. Parameters such as the number of articles, article citations, keywords, source impact, and countries of publication were used to analyse the documents and rank countries based on authors, productivity, article citations, and co-authorship. The analysis reveals production increased significantly from 2009 and has the most published documents in 2019 with a total of 74 articles. Asia’s most populous countries, India and China, were ranked first and second, respectively, and the USA third in terms of the most productive countries in the field of plant biopesticides. Countries in Europe and Africa however have fewer publications than expected in this field, given the fact that they are high consumers of pesticides. India, China, and the USA have 4.08%, 2.94%, and 12.5% multiple country publications (MCPs), respectively, with the USA having a stronger collaboration. Finally, there is a clear indication in this study that India and China are taking the lead in substituting synthetic pesticides with the alternative natural plant biopesticide.


2021 ◽  
Vol 13 (22) ◽  
pp. 12532
Author(s):  
Yuh-Shan Ho ◽  
Sharif A. Mukul

Mangroves are one the most productive ecosystems on Earth, and they are geographically located in the tropics and sub-tropics. Notwithstanding their critical role in providing a large number of environmental services and benefits as well as livelihood provisions, mangrove forests are being lost globally at an alarming rate. At the same time, they are increasingly recognized as a cost-effective nature-based climate solution for their carbon sequestration and storage capacity. Despite their enormous importance to people’s lives and the ecosystem, no bibliometric study on this topic has been published to our knowledge. Here, we provide a bibliometric analysis of the research on mangroves with research trends, most influential research based on citation count, and the origins (country and institution) of major research. Using the Science Citation Index Expanded (SCI-EXPANDED) database of the Web of Science Core Collection (Clarivate Analytics), we identified 13,918 documents published between 1990 and 2019. Nevertheless, 12,955 articles met our final criteria and were analyzed in detail. Six publications and their citations per publication (CPP2019) were applied to evaluate the publication performance of countries and institutes. When considering the top ten Web of Science subject categories, articles published on the ecology of mangroves had the highest CPP2019 of 28. Environmental sciences have been the major category since 2013. The USA dominated the total articles and single-author articles. The USA was also the most frequent partner of international collaborative publications. China published the most single-country articles, first-author articles, and corresponding-author articles. However, articles by the USA and Australia had a higher CPP2019. Sun Yat Sen University in China was the most active university. The Australian Institute of Marine Science dominated all kinds of publications with the top CPP2019. Together with the USA, Australia, China, India, Brazil, and Japan ranked both the top six on total publications and total publications in 2019. Our bibliometric study provides useful visualization of the past and current landscape of research on mangroves and emerging fields, to facilitate future research collaboration and knowledge exchange.


2021 ◽  
Author(s):  
Xiaonan Sheng ◽  
Huijuan Dai ◽  
Yonggang Song ◽  
Xueyun Ma

Abstract Background: Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer, and it lacks an efficient target treatment. Here, we aimed to gain knowledge on the development of TNBC research and explore potential treatment strategies.Methods: We analyzed 14,389 publications on TNBC from the Web of Science (WOS) over the past 20 years, from 2000 to 2020, using bibliometric methods. We evaluated the publication tendency of TNBC and the contributions of different countries. Institutions and journals with the highest number of TNBC publications were screened. Finally, the research focus of the TNBC publications were also analyzed.Results: TNBC publications have significantly increased in the past 20 years, with elevated relative research interest (RRI). The USA has the most TNBC-related publications with high quality, and China is the country with the most rapid growth tendency in TNBC publications. The University of Texas System is the institution with the most TNBC publications. Breast Cancer Research and Treatment is the journal that published the most TNBC-related publications. The top 30 publications with high citations are also listed. The researches focusing on TNBC in the past 20 years were separated into four main clusters: tumor biology, TNBC therapies, treatment sensitivity, and gene mutations. The research focus in TNBC ranked by appearing years reflects the development of TNBC treatment strategy, showing that targeting tumor immunity is now the main focus in TNBC research. Conclusions: Using bibliometric analysis, we initially revealed the increasing interest in TNBC research and summarized the publication tendency of TNBC. We also reported focused topics screened from publications in the past 20 years, indicating the main problems and research objectives of TNBC for the first time. Immune-related topics are becoming the focus of TNBC research.


2021 ◽  
Vol 2021 ◽  
pp. 1-12
Author(s):  
Huifang Xia ◽  
Shali Tan ◽  
Shu Huang ◽  
Peiling Gan ◽  
Chunyu Zhong ◽  
...  

Objective. To identify and evaluate characteristics of the most influential articles in achalasia research during the period 1995-2020. Methods. Articles in Scopus, Web of Science Core Collection (WoSCC), and PubMed were scanned from 1995 to 2020 with achalasia as the keyword. We retrieved the articles that met all criteria by descending order after using EndNote to remove the duplicated references. Our bibliometric analysis highlighted publication year, country, journals, and networks of keywords. Results. Fifteen percent of the top 100 most-cited articles were published in Annals of Surgery. They were performed in 15 countries, and most ( n = 55 ) were from the USA. The number of citations of the 482 articles ranged from 30 to 953, 38 of which had been published in American Journal of Gastroenterology. Those articles were from 31 countries, and most of the studies ( n = 217 ) had been performed in the USA. Most of articles ( n = 335 ) were clinical research. Treatments were hotspots in the field of achalasia in the past years. The most influential title words were “achalasia,” “esophagomyotomy,” “pneumatic dilation,” and “lower esophageal sphincter.” Conclusion. Our study offers a historical perspective on the progress of achalasia research and identified the most significant evolution in this field. Results showed treatment was the most influence aspect in achalasia.


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