scholarly journals A Mini Review on Non-augmentative Surgical Therapy of Peri-Implantitis—What Is Known and What Are the Future Challenges?

2021 ◽  
Vol 2 ◽  
Author(s):  
Kristina Bertl ◽  
Andreas Stavropoulos
Keyword(s):  
Surgical Treatment ◽  
Bone Loss ◽  
Bone Regeneration ◽  
Surgical Therapy ◽  
Treatment Approach ◽  
Future Research ◽  
Implant Surface ◽  
Research Challenges ◽  
Future Challenges ◽  
Open Flap Debridement

Non-augmentative surgical therapy of peri-implantitis is indicated for cases with primarily horizontal bone loss or wide defects with limited potential for bone regeneration and/or re-osseointegration. This treatment approach includes a variety of different techniques (e.g., open flap debridement, resection of peri-implant mucosa, apically positioned flaps, bone re-contouring, implantoplasty, etc.) and various relevant aspects should be considered during treatment planning. The present mini review provides an overview on what is known for the following components of non-augmentative surgical treatment of peri-implantitis and on potential future research challenges: (1) decontamination of the implant surface, (2) need of implantoplasty, (3) prescription of antibiotics, and (4) extent of resective measures.

scholarly journals The Treatment of Peri-Implant Diseases: A New Approach Using HYBENX® as a Decontaminant for Implant Surface and Oral Tissues

Antibiotics ◽  
2021 ◽  
Vol 10 (5) ◽  
pp. 512
Author(s):  
Michele Antonio Lopez ◽  
Pier Carmine Passarelli ◽  
Emmanuele Godino ◽  
Nicolò Lombardo ◽  
Francesca Romana Altamura ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Pathological Condition ◽  
Implant Surface ◽  
Probing Depth ◽  
Average Residual ◽  
Potential Benefits ◽  
Bone Level ◽  
Bone Gain ◽  
Open Flap Debridement

Background: Peri-implantitis is a pathological condition characterized by an inflammatory process involving soft and hard tissues surrounding dental implants. The management of peri-implant disease has several protocols, among which is the chemical method HYBENX®. The aim of this study is to demonstrate the efficacy of HYBENX® in the treatment of peri-implantitis and to compare HYBENX® with other chemical agents used in the surgical treatment of peri-implantitis. Methods: The present study included a population of ten subjects with severe peri-implantitis. The procedure used in the study involves the application of HYBENX® after open-flap debridement. Each patient has been followed for 12 months after a single application of the decontaminant agent. Clinical and radiographical parameters were recorded at baseline, 3 months, and 12 months after treatment completion. Results: At baseline, a mean pocket probing depth (PPD) of 7.3 ± 0.5 mm and a mean clinical attachment level (CAL) of 8.8 ± 0.8 mm was recorded. An average residual PPD of 4.2 ± 0.5 mm and a mean CAL of 5.2 ± 0.8 mm were observed after 1 year. Additionally, the average of bone gain was about 3.4 mm, with a mean marginal bone level (MBL) change from 5.8 mm (baseline) to 2.4 mm (12 months). In total, 90% of the treated implants reached the success rate after the 1-year follow-up. Only in one case out of ten treated implants was resolution of the disease not achieved. Conclusion: Clinical improvements highlight that the procedure of open-flap debridement (OFD) + HYBENX® may be considered an effective technique in the treatment of peri-implantitis. From the results obtained, it can be concluded that the use of HYBENX® in the surgical treatment of peri-implantitis is promising. Overall, this protocol demands further studies to better understand the role and potential benefits of HYBENX® in the treatment of peri-implantitis.

Intrabony Defects and Non-Surgical Treatment

2014 ◽  
Vol 3 (3) ◽  
pp. 48-50 ◽  
Author(s):  
Luigi Nibali
Keyword(s):  
Surgical Treatment ◽  
Bone Loss ◽  
Bone Regeneration ◽  
Disease Progression ◽  
Surgical Procedures ◽  
Scientific Evidence ◽  
Periodontal Treatment ◽  
Intrabony Defects ◽  
Risk Of Progression ◽  
Non Surgical Treatment

Periodontitis can lead to vertical bone loss with the creation of ‘intrabony defects’, associated with higher risk of progression if left untreated. Intrabony defects are considered candidates for periodontal surgical procedures, in order to arrest disease progression and achieve bone regeneration. This paper brings forward anecdotal and scientific evidence from the literature to describe how even non-surgical periodontal treatment can result in clinical and radiographic resolution of periodontal intrabony defects.

scholarly journals Surgical Treatment of Severe Peri-Implantitis Using a Round Titanium Brush for Implant Surface Decontamination: A Case Report With Clinical Reentry

2017 ◽  
Vol 43 (3) ◽  
pp. 218-225 ◽  
Author(s):  
Yin-Zhe An ◽  
Jae-Hong Lee ◽  
Young-Ku Heo ◽  
Jung-Seok Lee ◽  
Ui-Won Jung ◽  
...  
Keyword(s):  
Case Report ◽  
Surgical Treatment ◽  
Bone Loss ◽  
Reliability And Validity ◽  
Surgical Approaches ◽  
Implant Surface ◽  
Common Cause ◽  
Regenerative Approach ◽  
Clinical And Radiological Results

The most common cause of peri-implantitis is the accumulation of plaque and the formation of a biofilm on the implant surface. Terminating the development of the disease requires the biofilm to be removed from the implant surface. This paper describes 2 cases of severe peri-implantitis lesions treated through surgical approaches. Complete mechanical debridement with a round titanium brush was mainly performed to detoxify and modify the affected implant surface. A regenerative approach was then performed. In both cases, the surgical procedure was effective in arresting the peri-implantitis, and clinical reentry revealed uneventful healing of the existing bone defect. No further radiographic bone loss was observed over the 2-year follow-up period. This technique has the advantage of effective cleaning the contaminated implant surface, producing positive clinical and radiological results. However, further studies involving more cases are necessary to verify the reliability and validity of this technique.

scholarly journals How to handle minor and major bone loss in the shoulder? Current concepts

2020 ◽  
Vol 5 (3) ◽  
pp. 117-122
Author(s):  
Giovanni Di Giacomo ◽  
Mattia Pugliese ◽  
Denny Tjiauw Tjoen Lie ◽  
Andrew Chia Chen Chou ◽  
Jiwu Chen ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Bone Loss ◽  
Treatment Failure ◽  
Treatment Choice ◽  
Glenoid Bone Loss ◽  
Anterior Shoulder Instability ◽  
Future Research ◽  
Bone Block ◽  
Cause Of Failure ◽  
The Right

Anterior shoulder instability is a significant problem in orthopaedic surgery. It carries a heavy burden on quality of life, especially in young, active patients. Surgical treatment is therefore often carried out in this population. Several strategies can effectively address this issue. Yet, the consensus is lacking on the parameters which favour one technique over another, especially when bone loss is present. This is because of the complex, dynamic interplay between bone loss on the humeral side (ie, Hill-Sachs lesion) and glenoid bone loss, which is a common occurrence and defined as ‘bipolar’. There is an ongoing debate over the percentage of glenoid bone loss warranting bone block procedures: 13.5–15% is an indicator for such procedures (ie, Latarjet), although this value is still considered controversial and not uniformly accepted. A multitude of other factors (ie, age, sex, level of activity and so on) come into play alongside bipolar bone loss and the weight of each factor has yet to be fully elucidated. Also, refining the algorithm for the right procedure in the right patients will reduce the number of side effects stemming from initial, suboptimal treatment choice. Knowing how to manage previous surgical treatment failure is also key for the treating orthopaedic surgeon, who must be able to address the root cause of failure and react accordingly and effectively. This paper analyses key factors in treatment choice, the current stance of the literature on varying degrees of bone loss and choices on surgical treatment failure, lack of evidence and need for future research.

Management of Retrograde Peri-implantitis: A Clinical Case Report

2006 ◽  
Vol 32 (6) ◽  
pp. 308-312 ◽  
Author(s):  
Khurram Ataullah ◽  
Loh Fun Chee ◽  
Lim Lum Peng ◽  
Henry Ho Kim Lung
Keyword(s):  
Case Report ◽  
Bone Loss ◽  
Bone Regeneration ◽  
Dental Implants ◽  
Clinical Case ◽  
Guided Bone Regeneration ◽  
Surgical Debridement ◽  
Implant Surface ◽  
Exact Etiology ◽  
Current Article

Abstract The term retrograde peri-implantitis has been commonly used to describe lesions in the periapical region of dental implants. There are very few reports on this condition, and the exact etiology and pathogenesis are subject to speculation. Management of retrograde peri-implantitis is even more scarcely discussed in the literature. The current article briefly reviews the literature on this subject and presents a case report of retrograde peri-implantitis. Special emphasis is placed on the management of the condition, and different strategies are critically evaluated. If the fixture is stable despite bone loss in the periapical region, it is suggested that surgical debridement be carried out with the use of a surface antiseptic like chlorhexidine. Also all possible efforts should be made to prevent damage to the implant surface. Bone loss due to this condition may be regenerated on the basis of the principle of guided bone regeneration.

scholarly journals The Role of Alcohol, LPS Toxicity, and ALDH2 in Dental Bony Defects

Biomolecules ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 651
Author(s):  
Hsiao-Cheng Tsai ◽  
Che-Hong Chen ◽  
Daria Mochly-Rosen ◽  
Yi-Chen Ethan Li ◽  
Min-Huey Chen
Keyword(s):  
Bone Loss ◽  
Bacterial Infection ◽  
Bone Regeneration ◽  
Alcohol Drinking ◽  
Bacterial Species ◽  
Dominant Negative ◽  
Enzyme Inactivation ◽  
Wild Type ◽  
Micro Computed Tomography ◽  
Dominant Negative Mutation

It is estimated that 560 million people carry an East Asian-specific ALDH2*2 dominant-negative mutation which leads to enzyme inactivation. This common ALDH2 polymorphism has a significant association with osteoporosis. We hypothesized that the ALDH2*2 mutation in conjunction with periodontal Porphyromonas gingivalis bacterial infection and alcohol drinking had an inhibitory effect on osteoblasts and bone regeneration. We examined the prospective association of ALDH2 activity with the proliferation and mineralization potential of human osteoblasts in vitro. The ALDH2 knockdown experiments showed that the ALDH2 knockdown osteoblasts lost their proliferation and mineralization capability. To mimic dental bacterial infection, we compared the dental bony defects in wild-type mice and ALDH2*2 knockin mice after injection with purified lipopolysaccharides (LPS), derived from P. gingivalis which is a bacterial species known to cause periodontitis. Micro-computed tomography (micro-CT) scan results indicated that bone regeneration was significantly affected in the ALDH2*2 knockin mice with about 20% more dental bony defects after LPS injection than the wild-type mice. Moreover, the ALDH2*2 knockin mutant mice had decreased osteoblast growth and more dental bone loss in the upper left jaw region after LPS injection. In conclusion, these results indicated that the ALDH2*2 mutation with alcohol drinking and chronic exposure to dental bacterial-derived toxin increased the risk of dental bone loss.

scholarly journals Large-Scale Object Monitoring in Internet-of-Things: Energy-Efficient Perspectives

Electronics ◽  
2021 ◽  
Vol 10 (4) ◽  
pp. 461
Author(s):  
Yongbin Yim ◽  
Euisin Lee ◽  
Seungmin Oh
Keyword(s):  
Energy Efficient ◽  
Large Scale ◽  
Future Research ◽  
Technological Evolution ◽  
Node Density ◽  
Mobile Objects ◽  
Research Challenges ◽  
Energy Efficient Communication ◽  
Efficient Communication ◽  
Architectural Principles

Recently, the demand for monitoring a certain object covering large and dynamic scopes such as wildfires, glaciers, and radioactive contaminations, called large-scale fluid objects (LFOs), is coming to the fore due to disasters and catastrophes that lately happened. This article provides an analytic comparison of such LFOs and typical individual mobile objects (IMOs), namely animals, humans, vehicles, etc., to figure out inherent characteristics of LFOs. Since energy-efficient monitoring of IMOs has been intensively researched so far, but such inherent properties of LFOs hinder the direct adaptation of legacy technologies for IMOs, this article surveys technological evolution and advances of LFOs along with ones of IMOs. Based on the communication cost perspective correlated to energy efficiency, three technological phases, namely concentration, integration, and abbreviation, are defined in this article. By reviewing various methods and strategies employed by existing works with the three phases, this article concludes that LFO monitoring should achieve not only decoupling from node density and network structure but also trading off quantitative reduction against qualitative loss as architectural principles of energy-efficient communication to break through inherent properties of LFOs. Future research challenges related to this topic are also discussed.

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