scholarly journals Use of Archived Neonatal Bloodspots for Examining Associations between Prenatal Exposure to Potentially Traumatic or Stressful Life Events, Maternal Herpesvirus Infection and Lifetime History of Generalized Anxiety Disorder in Offspring

2016 ◽  
Vol 4 ◽  
Author(s):  
Amanda M. Simanek ◽  
Monica Uddin ◽  
Robert H. Yolken ◽  
Allison E. Aiello
Keyword(s):  
Anxiety Disorder ◽  
Life Events ◽  
Generalized Anxiety Disorder ◽  
Prenatal Exposure ◽  
Stressful Life Events ◽  
Stressful Life ◽  
Generalized Anxiety ◽  
Herpesvirus Infection ◽  
Lifetime History ◽  
History Of

scholarly journals THE IMPACT OF STRESSFUL LIFE EVENTS ON RELAPSE OF GENERALIZED ANXIETY DISORDER

2012 ◽  
Vol 29 (5) ◽  
pp. 386-391 ◽  
Author(s):  
Jennifer L. Francis ◽  
Ethan Moitra ◽  
Ingrid Dyck ◽  
Martin B. Keller
Keyword(s):  
Anxiety Disorder ◽  
Life Events ◽  
Generalized Anxiety Disorder ◽  
Stressful Life Events ◽  
Stressful Life ◽  
Generalized Anxiety ◽  
The Impact

The impact of generalized anxiety disorder and stressful life events on risk for major depressive episodes

2006 ◽  
Vol 36 (6) ◽  
pp. 789-795 ◽  
Author(s):  
JOHN M. HETTEMA ◽  
JONATHAN W. KUHN ◽  
CAROL A. PRESCOTT ◽  
KENNETH S. KENDLER
Keyword(s):  
Anxiety Disorder ◽  
Life Events ◽  
Generalized Anxiety Disorder ◽  
Stressful Life Events ◽  
Stressful Life ◽  
Generalized Anxiety ◽  
Major Depressive ◽  
Major Depressive Episodes ◽  
Depressive Episodes ◽  
The Impact

Background. Both generalized anxiety disorder (GAD) and stressful life events (SLEs) are established risk factors for major depressive disorder, but no studies exist that examine the interrelationship of their impact on depressive onsets. In this study, we sought to analyze the joint effects of prior history of GAD and recent SLEs on risk for major depressive episodes, comparing these in men and women.Method. In a population-based sample of 8068 adult twins, Cox proportional hazard models were used to predict onsets of major depression from reported prior GAD and last-year SLEs rated on long-term contextual threat.Results. For all levels of threat, prior GAD increases risk for depression, with a monotonic relationship between threat level and risk. While females without prior GAD consistently show higher depressive risk than males, this is no longer the case in subjects with prior GAD who have experienced SLEs. Rather, males appear to be more vulnerable to the depressogenic effects of both prior GAD and SLEs.Conclusion. The effects of prior GAD and SLEs jointly increase the risk of depression in both sexes, but disproportionately so in males.

Fatigue in a community sample of twins

2003 ◽  
Vol 33 (2) ◽  
pp. 263-281 ◽  
Author(s):  
P. F. SULLIVAN ◽  
P. KOVALENKO ◽  
T. P. YORK ◽  
C. A. PRESCOTT ◽  
K. S. KENDLER
Keyword(s):  
Anxiety Disorder ◽  
Major Depression ◽  
Life Events ◽  
Generalized Anxiety Disorder ◽  
Latent Class ◽  
Stressful Life Events ◽  
Community Sample ◽  
Stressful Life ◽  
Generalized Anxiety ◽  
Addictive Disorders

Background. Fatigue is a complex symptom associated with many physiological, psychological and pathological processes. Its correlates and typology remain inadequately understood.Method. These data were from two large, longitudinal twin studies. Trained interviewers enquired as to the presence of a [ges ]5 day period in the previous year of fatigue or tiredness that interfered with daily activities. A range of potential correlates was assessed in a structured interview: demography; health beliefs; the presence of nine physical disorders; mood, anxiety and addictive disorders; neuroticism and extraversion; recollections of parental rearing; and nine stressful life events. Statistical analyses included logistic regression, CART, MARS, latent class analysis and univariate twin modelling.Results. Data were available for interfering fatigue (IF) on 7740 individual twins (prevalence 9·9% in the previous year). IF was significantly associated with 42 of 52 correlates (most strongly with major depression, generalized anxiety disorder, reported major health problems and neuroticism). Multivariate analyses demonstrated that IF is a highly complex construct with different sets of correlates in its subtypes. There were two broad clusters of correlates of IF: (a) major depression, generalized anxiety disorder and neuroticism; and (b) beliefs of ill health coexisting with alcoholism and stressful life events. Twin analyses were consistent with aetiological heterogeneity – genetic effects may be particularly important in women and shared environmental effects in men.Conclusions. IF is a complex and common human symptom that is highly heterogeneous. More precise understanding of the determinants of IF may lead to a fuller understanding of more extreme conditions like chronic fatigue syndrome.

scholarly journals Longitudinal investigation of the role of temperament and stressful life events in childhood anxiety

2014 ◽  
Vol 26 (2) ◽  
pp. 437-449 ◽  
Author(s):  
Suzanne Broeren ◽  
Carol Newall ◽  
Helen F. Dodd ◽  
Ruth Locker ◽  
Jennifer L. Hudson
Keyword(s):  
Anxiety Disorder ◽  
Life Events ◽  
Stressful Life Events ◽  
Negative Life Events ◽  
Childhood Anxiety ◽  
Diagnostic Interview ◽  
Anxiety Symptoms ◽  
Positive Behavior ◽  
Stressful Life ◽  
The Impact

AbstractThe current study investigated the longitudinal relationships among behavioral inhibition (BI), life events, and anxiety in a sample of 102 BI children and 100 behaviorally uninhibited (BUI) children aged 3 to 4 years. Children's parents completed questionnaires on BI, stressful life events, and anxiety symptoms, and were administered a diagnostic interview three times in a 5-year period. In line with our hypotheses, negative life events, particularly negative behavior-dependent life events (i.e., life events that are related to the children's own behaviors), and the impact of negative life events were predictive of increases in subsequent anxiety symptoms, the likelihood of having an anxiety disorder, and increased number of anxiety diagnoses over the 5-year follow-up period. Experiencing more positive, behavior-independent life events decreased the risk of being diagnosed with an anxiety disorder. Furthermore, differences were found in life events between BI and BUI children. That is, BI children experienced fewer positive and specifically positive behavior-dependent life events, and the impact of these positive life events was also lower in BI children than in BUI children. However, BI did not interact with life events in the prediction of anxiety problems as hypothesized. Therefore, this study seems to indicate that BI and life events act as additive risk factors in the development of anxiety problems.

The effects of co-morbidity on the onset and persistence of generalized anxiety disorder in the ICPE surveys

2002 ◽  
Vol 32 (7) ◽  
pp. 1213-1225 ◽  
Author(s):  
R. C. KESSLER ◽  
L. H. ANDRADE ◽  
R. V. BIJL ◽  
D. R. OFFORD ◽  
O. V. DEMLER ◽  
...  
Keyword(s):  
Anxiety Disorder ◽  
Generalized Anxiety Disorder ◽  
Composite International Diagnostic Interview ◽  
The United States ◽  
Elevated Risk ◽  
World Health ◽  
Generalized Anxiety ◽  
Co Morbidity ◽  
First Onset ◽  
History Of

Background. Although it is well known that generalized anxiety disorder (GAD) is highly co-morbid with other mental disorders, little is known about the extent to which earlier disorders predict the subsequent first onset and persistence of GAD. These associations are examined in the current report using data from four community surveys in the World Health Organization (WHO) International Consortium in Psychiatric Epidemiology (ICPE).Method. The surveys come from Brazil, Canada, the Netherlands and the United States. The Composite International Diagnostic Interview (CIDI) was used to assess DSM-III-R anxiety, mood and substance use disorders in these surveys. Discrete-time survival analysis was used to examine the associations of retrospectively reported earlier disorders with first onset of GAD. Logistic regression analysis was used to examine the associations of the disorders with persistence of GAD.Results. Six disorders predict first onset of GAD in all four surveys: agoraphobia, panic disorder, simple phobia, dysthymia, major depression and mania. With the exception of simple phobia, only respondents with active disorders have elevated risk of GAD. In the case of simple phobia, in comparison, respondents with a history of remitted disorder also have consistently elevated risk of GAD. Simple phobia is also the only disorder that predicts the persistence of GAD.Conclusions. The causal processes linking temporally primary disorders to onset of GAD are likely to be state-dependent. History of simple phobia might be a GAD risk marker. Further research is needed to explore the mechanisms involved in the relationship between simple phobia and subsequent GAD.

scholarly journals Stressful life events among individuals with a history of eating disorders: a case-control comparison

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Selma Ø. Lie ◽  
Cynthia M. Bulik ◽  
Ole A. Andreassen ◽  
Øyvind Rø ◽  
Lasse Bang
Keyword(s):  
Eating Disorders ◽  
Sexual Assault ◽  
Binge Eating ◽  
Life Events ◽  
Emotional Abuse ◽  
Stressful Life Events ◽  
Case Control ◽  
Stressful Life ◽  
Close Relative ◽  
History Of

Abstract Background Experiencing stressful life events (SLEs) can negatively impact mental health and increase risk for psychiatric disorders including eating disorders (EDs). Previous research has shown that childhood sexual abuse is associated with some EDs, but less is known about the association between other non-sexual SLEs and EDs. Method A case-control study of individuals with (n = 495, age mean ± SD = 29.1 ± 9.8 years) and without (n = 395, age = 30.2 ± 11.7) self-reported lifetime history of EDs was conducted to compare history of self-reported SLEs. Participants reported history of sexual (e.g., rape, other sexual assault) and non-sexual (e.g., emotional abuse, assault, bereavement) life events using an adaptation of the Stressful Life Events Screening Questionnaire. Individuals with EDs were divided into ED subtypes along the restricting – binge eating/purging spectrum to examine subtype differences. Logistic regressions were conducted for each SLE and ED subtype to obtain odds ratios (ORs). We report p-values corrected for multiple comparisons. Results Exposure to any SLE was significantly more common in individuals with EDs than in controls (OR = 2.47, p < .001). Specifically, rape, other sexual assault, and emotional abuse were significantly more common among individuals with a history of binge-eating/purging ED subtypes (ORs = 2.15–3.58, p’s < .01) compared with controls. Furthermore, history of life-threatening disease and loss of a close relative/partner/friend were associated with some ED subtypes. The association between SLEs and EDs was stronger for individuals who had experienced multiple SLEs. Conclusion By investigating a range of different SLEs, we showed that both sexual and non-sexual SLEs were more common in individuals with a history of EDs (binge-eating/purging subtypes) than controls. Results highlight the importance of assessing a variety of past SLEs in risk assessment for different EDs.

scholarly journals Clinical correlation between Migraine and Generalized Anxiety Disorders: a literature review

2021 ◽  
Author(s):  
Samantha Lia Ziotti Bohn Gonçalves Soares ◽  
Letícia Santana Ferreira Gonçalves ◽  
Emily Thauara de Souza ◽  
Pollyana Yuri Salles Suguinoshita ◽  
Luana Isla Rocha Alves ◽  
...  
Keyword(s):  
Anxiety Disorder ◽  
Anxiety Disorders ◽  
Generalized Anxiety Disorder ◽  
Low Income ◽  
Epidemiological Studies ◽  
Generalized Anxiety ◽  
Epidemiological Factors ◽  
Painful Sensation ◽  
Generalized Anxiety Disorders ◽  
History Of

Background: Migraine and anxiety are common neuro-psychiatric disorders in clinical practice, sharing symptoms and epidemiological factors among themselves. The presence of both pathologies in the same individual is frequently reported in the literature. Objectives: To report the clinical and epidemiological correlations established between generalized anxiety disorder and migraine. Methodology: Systematic review of studies published between 2016 and 2021, exploring the association between generalized anxiety disorders and Migraine. The descriptors “association”, “Migraines” and “Generalized Anxiety Disorder” were used in the LILACS, SCIELO and PUBMED databases. Fourteen articles were selected, mostly dealing with epidemiological studies. Results: Evidence suggests that these pathologies are associated and share common symptoms, pathophysiology and epidemiological factors. Studies corroborate that anxiety and painful sensation are more strongly associated with migraine than with other psychiatric illnesses. It has also demonstrated some characteristics of patients who are predisposed to develop both comorbidities such as smoke, low income and a history of other previous diseases. Common triggering factors such as pain, sleep disorders and stress can also contribute to the association between pathologies. Conclusions: Based on the studies analyzed in full, the high prevalence of both diseases in the same individual highlights the importance of research on the cause and consequence relationship between Anxiety and Migraine, since this is not yet clarified in the medical literature. In addition, paying attention to migraine correlation to generalized anxiety disorder increases the quality of life of the patient in the short and long term, as well as help in the choice of better treatments.

Sign in / Sign up

Export Citation Format

Share Document