scholarly journals Global Perspectives on Immunization Against SARS-CoV-2 During Pregnancy and Priorities for Future Research: An International Consensus Paper From the World Association of Infectious Diseases and Immunological Disorders

2021 ◽  
Vol 12 ◽  
Author(s):  
Bahaa Abu-Raya ◽  
Shabir A. Madhi ◽  
Saad B. Omer ◽  
Gayatri Amirthalingam ◽  
Michelle L. Giles ◽  
...  

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in pregnancy is associated with a higher risk for severe morbidity and mortality when compared with infection in non-pregnant women of childbearing age. An increasing number of countries recommend immunization against SARS-CoV-2 in pregnant women. Recent studies provide preliminary and supportive evidence on safety, immunogenicity and effectiveness of coronavirus disease 2019 (COVID-19) vaccines in pregnant women; however, important knowledge gaps remain which warrant further studies. This collaborative consensus paper provides a review of the current literature on COVID-19 vaccines in pregnant women, identifies knowledge gaps and outlines priorities for future research to optimize protection against SARS-CoV-2 in the pregnant women and their infants.

2017 ◽  
Vol 18 (1) ◽  
Author(s):  
K Michael Hambidge ◽  
Nancy F Krebs ◽  
Ana Garcés ◽  
Jamie E Westcott ◽  
Lester Figueroa ◽  
...  

2018 ◽  
Vol 55 (5) ◽  
pp. 633-641 ◽  
Author(s):  
Sarah F. Schillie ◽  
Lauren Canary ◽  
Alaya Koneru ◽  
Noele P. Nelson ◽  
Wade Tanico ◽  
...  

2016 ◽  
Vol 3 (1) ◽  
pp. 48
Author(s):  
Annisaa’ Nurmasari ◽  
Fatimah Fatimah ◽  
Febrina Suci Hati

<p>HIV infection in pregnant women can threaten the life of the mother and the mother can transmit the virus to their babies. Sleman PHC registered 2 people including one pregnant woman and one women of childbearing age in the year of 2014. Incidence of pregnant women suffering from HIV-AIDS in 2014 is 1 patients and detected from PITC test results for 7 weeks in a row is 1 patient. And in January year of 2015 found 1 patient with 3 times test and the results was positive. The purpose of this study was to determine relationship between Knowledge Level of Pregnant women about HIV/AIDS and Behaviour of PITC (Provider Initiated Test and Counselling) test. This study was a quantitative analysis of correlation with cross-sectional design. The population of this study were all pregnant women checkups at the health center in Yogyakarta Sleman. The sampling technique was used accidental sampling study which consisted of 72 respondents. The analysis used univariate and bivariate. The results showed that most respondents aged 20-35 (72.2%), senior high school education (47.2%) and work as a housewife (IRT) (38.9%). Most respondents have good knowledge about HIV/AIDS were 50 respondents (69.4%). Most respondents perform checks PITC were 71 respondents (98.6%). There was no relationship between knowledge level of pregnant women about HIV/AIDS and Behaviour of PITC (p-value=0.243&gt;0.005). In Conclusion, There was no relationship between knowledge level of pregnant women about HIV/AIDS and Behaviour of PITC in Sleman, Yogyakarta.</p>


2019 ◽  
Vol 29 (Supplement_4) ◽  
Author(s):  
T Petkova ◽  
S Pachkova ◽  
T z Doichinova ◽  
S Aleksandrova-Yankulovska

Abstract Background Parvovirus B19 is a widespread infection in childhood. Seroprevalence of anti-Parvovirus B19 increases with age and about 60% to 70% of women of childbearing age have serological evidence of past exposure to virus. Diaplacental Parvovirus B19 infection in pregnant women can lead to anaemia, non-immune hydrops fetalis and foetal death. The aim of the study is determining the susceptibility to Parvovirus B19 in childbearing age women. Methods We conducted a prospective seroepidemiological study in which 90 healthy women of childbearing age (19 to 40 years) were tested during the period September-October 2018 in Medical Center “Clinical Institute for Reproductive Medicine”- Pleven, Bulgaria. Participants were surveyed on a voluntary basis. The exclusion criteria were: presence of autoimmune disorder, immunosuppressive states, malignancy and populations at risk such as persons under 18 years of age and pregnant women. The presence of specific Parvovirus B19 IgG was detected using a standardized anti-Parvovirus B19 (IgG) ELISA kit. The demographic and anamnestic data were collected for each participant in Case Report Form. Results The average age of the women was 31.4 ± 4.9 years. Dominating were women with higher education (52.2%) living in urban areas (92.2%). The survey results showed that 37.8% of women were positive for anti-Parvovirus B19 IgG, 61.1% were negative and 1.1% equivocal. Immunty to the virus increased from 27.3% to 45% with age. There was no significant correlation between the presence of antibodies and the demographic factors (living area, education and number of family members). Conclusions The results of this study imply that 61.1% of the childbearing age women in Pleven region are susceptible to infection with Parvovirus B19. Because of the high susceptibility to Parvovirus B19, active monitoring of risk groups pregnant women for the prevention of fetal complications is recommended. Key messages There is no specific treatment or prophylaxis against Parvovirus B19 infection and epidemiological surveillance requires the introduction of effective preventive measures at the public health level. Active monitoring in childbearing age women is necessary to reduce the risk of fetal damage and the cost of healthcare associated with the infection.


Vaccines ◽  
2020 ◽  
Vol 8 (2) ◽  
pp. 214
Author(s):  
Claudia M. Trombetta ◽  
Emanuele Montomoli ◽  
Simonetta Viviani ◽  
Rosa Coluccio ◽  
Serena Marchi

Varicella is a highly contagious, infectious disease caused by the varicella-zoster virus. Those at higher risk of severe complications are immunocompromised individuals, adults, non-immune pregnant women, and newborns. According to the gestational time, when varicella-zoster virus infection is acquired during pregnancy, serious complications can potentially occur for both the woman and the fetus. The present study was conducted to assess the profile of varicella susceptibility in pregnant women in Apulia, a large region in Southern Italy, from 2016 to 2019. The data showed that pregnant women between the age of 15–24 and 40–49 years, the youngest and the oldest, respectively, are the most protected against varicella-zoster virus infection, exceeding the prevalence rate of 90%. Conversely, pregnant women between the age of 25 and 34 years seem to be the most vulnerable and the most at risk for acquiring varicella-zoster virus infection during pregnancy. Analysis of the immunity status against varicella should be introduced as a screening test before pregnancy, together with a strategic vaccination campaign targeting non-immune women of childbearing age, in order to reduce the risk of congenital and perinatal varicella.


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