scholarly journals Utilization Trends of Antiviral and Antifungal Agents for Human Systemic Use in Tanzania From 2010 to 2017 Using the World Health Organization Collaborating Centre for Drug Statistics Methodology

2021 ◽  
Vol 2 ◽  
Author(s):  
Hafidh Hamim ◽  
Raphael Z. Sangeda ◽  
Maganga Bundala ◽  
Sonia Mkumbwa ◽  
Adonis Bitegeko ◽  
...  

IntroductionThe increase in antimicrobial consumption contributes to the emergence of antimicrobial resistance (AMR). Many studies have investigated the patterns of antibacterial consumption and antibacterial resistance. However, there is a paucity of data on the utilization of antivirals and antifungals in low and middle-income countries to serve as a baseline for monitoring and surveillance of AMR. Therefore, this study determined Tanzania’s systemic antifungal and antiviral utilization trends from 2010 to 2017, based on the Tanzania Medicines and Medical Devices Authority (TMDA) medicine importation archives.MethodologyAn analytical, longitudinal retrospective survey covering 2010 to 2017 was conducted. The study utilized the Anatomical Therapeutic and Chemical (ATC) classification and Defined Daily Dose (DDD) developed by the World Health Organization (WHO) Collaborating Centre for Drug Statistics and the WHO Collaboration Centre for International Drug Consumption Monitoring. Human medicine importation data were collected from TMDA headquarters and used to assess the systemic antiviral and antifungal consumption trends. The importation data included the date, generic name, strength, brand name, currency, quantity, ATC classification, supplier country, port of entry and product supplier. The data were cleaned, reorganized and analyzed. Reference was made to the latest revised DDD list to assign antifungals and antivirals to their respective ATC/DDDs and then adjusted to the population estimates from the National Bureau of Statistics of Tanzania.ResultsThere was a high proportion of systemic antivirals and antifungals utilization with 367.1 and 10.8 DDD per 1000 inhabitants per day (DID) respectively over eight years. In regression model, there was a significant increase in both antiviral (p-value = 0.043) and antifungal (p-value = 0.015) agents’ utilization trends in Tanzania in the study period. Fluconazole had the highest proportion of utilization for antifungals, followed by ketoconazole, itraconazole, miconazole and amphotericin B. For systemic antivirals, a high proportion was attributed to antiretrovirals used for HIV infections.ConclusionFindings from this study suggest an increase in the utilization of systemic antiviral and antifungal agents. These findings may be used to further benchmark utilization and AMR studies in Tanzania.

Antibiotics ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 58
Author(s):  
Gulzira Zhussupova ◽  
Dinara Utepova ◽  
Galiya Orazova ◽  
Saule Zhaldybayeva ◽  
Galina Skvirskaya ◽  
...  

The purpose of this study is to conduct a comparative analysis of the consumption of antibiotics for systemic use reimbursed by the state in Kazakhstan for 2017–2019 with the Access, Watch, and Reserve classification (AWaRe 2019) of the World Health Organization (WHO). The evaluation of the consumption of antibiotics for systemic use in Kazakhstan for 2017–2019 was carried out using the ATC/DDD methodology in accordance with the WHO AWaRe classification. The study used data on all antibiotics that were centrally purchased by a single purchaser during the study period. To understand how often Access group antibiotics are taken in Kazakhstan, the top-10 most consumed antibiotics were additionally studied. The results of a comparative analysis of the antibiotics for systemic use consumption for 2017–2019 by the Access, Watch, and Reserve groups showed a negative trend of a decrease in the consumption of Access group drugs from 1.17 defined daily dose (DDDs) per 1000 inhabitants per day (DID) (39%) in 2017 to 0.59 DID (30%) in 2019. There is an increase in consumption of Watch group antibiotics from 1.84 DID (61%) in 2017 to 1.37 DID (68%) in 2019, as well as an increase in consumption of Reserve antibiotics from 0.001 DID (0.03%) to 0.4 DID (2.11%). In recent years in Kazakhstan, there has been a decrease in the consumption of Access group antibiotics. In addition, the Watch group antibiotics are widely consumed with a certain upward trend. In 2019, one Reserve antibiotic was included in the top-10 most commonly consumed antibiotics. There is a predominant consumption of parenteral forms of antibiotics for systemic use in the country.


2021 ◽  
Vol 3 (3) ◽  
pp. 437-444
Author(s):  
Sri Nur Hartiningsih ◽  
Eka Oktavianto ◽  
Niken Setyaningrum

Penderita HIV makin meningkat dari tahun ke tahun, penyakit ini memperburuk keadaan fisik maupun psikososial bagi penderitanya sehingga dapat memperburuk kualitas hidupnya. Pada penderita HIV spiritualitas dianggap sebagai hal yang penting, karena dengan spiritualitas akan menurunkan rasa putus asa,  hidup lebih bermakna sehingga akan meningkatkan kualitas hidup pada penderita HIV. Penelitian ini bertujuan untuk mengetahui hubungan tingkat spiritualitas dengan kualitas hidup penderita HIV di Yayasan Victory Plus Yogyakarta. Penelitian ini merupakan jenis penelitian kuantitatif dengan rancangan cross sectional. Pengambilan sampel yang digunakan pada penelitian ini menggunakan Total Sampling yaitu sebanyak 35 responden. Instrumen penelitian yang digunakan yaitu kuesioner spiritualitas SOI  (Spirituality Orientation Inventory) dan kualitas hidup WHOQOL-HIV BREF (The World Health Organization Quality Of Life). Analisis ini menggunakan uji Kendall Tau. Spiritualitas berhubungan dengan kualitas hidup penderita HIV . Spiritualitas berhubungan dengan kualitas hidup penderita HIV dengan hasil dari correlations sebesar 0,358 dengan nilai signifikan yaitu sebesar 0,000 (p value < 0,05).


2019 ◽  
Vol 13 (1) ◽  
pp. 76-83
Author(s):  
Surmiasih Surmiasih ◽  
Noven Winarsi ◽  
Wahidun Wahidun

THE EFFECTIVENESS OF REPRODUCTIVE HEALTH EDUCATION AMONG FEMALE ADOLESCENTSBackground: The World Health Organization states that poor women's reproductive health problems have reached 33% of the total burden of diseases suffered by women in the world. In Indonesia alone 75% of women have experienced vaginal discharge at least once in their lives. In Lampung, it was recorded that the implementation of health promotion or health education about hygiene behavior regarding the care of reproductive organs in adolescents was 20.29% of teenagers doing good hygiene behavior.Purpose: Knowing of the effectiveness of reproductive health education among female adolescentsMethods: This research is a type of quantitative research with quasi experimental design, one group pretest-post test design approach. The population is 124 female students. The sampling technique in this study uses the total population.Results: There was an effect of health education on the ability of female adolescents in the care of reproductive organs, obtained p-value 0.001.Conclusion: expected to increase knowledge about reproductive health for adolescents and how to care for good reproductive organs so that adolescents avoid the adverse effects caused if they do not treat reproductive organs. Keywords   : Reproductive health education, female, adolescents Pendahuluan: World Health Organization menyatakan masalah kesehatan reproduksi perempuan yang buruk telah mencapai 33% dari jumlah total beban penyakit yang diderita para perempuan di dunia. Di Indonesia sendiri 75% wanita pernah mengalami keputihan minimal satu kali dalam hidupnya. Di Lampung tercatat pelaksaan promosi kesehatan atau pendidikan kesehatan tentang perilaku hygiene tentang perawatan organ reproduksi pada remaja sebanyak 20,29% remaja melakukan perilaku hygiene yang baik.Tujuan: Diketahui adanya pengaruh pendidikan kesehatan terhadap kemampuan remaja puteri dalam perawatan organ reproduksi.Metode: Penelitian ini merupakan jenis penelitian kuantitatif dengan desain quasi eksperimental design dengan pendekatan one group pretest-posttest. .Jumlah populasi adalah 124 siswi.Teknik pengambilan sampel dalam penelitian ini menggunakan total population.Hasil:  Ada pengaruh pendidikan kesehatan terhadap kemampuan remaja puteri dalam perawatan organ reproduksi, didapatkan p-value 0,001.Simpulan: Seluruh siswa dapat menambah pengetahuan tentang kesehatan reproduksi dan cara merawat organ reproduksi yang baik sehingga remaja terhindar dari efek buruk yang ditimbulkan jika mereka tidak merawat organ reproduksi.


2017 ◽  
Vol 79 (07) ◽  
pp. 526-527

Coenen M et al. [Recommendation for the collection and analysis of data on participation and disability from the perspective of the World Health Organization]. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 2016; 59: 1060–1067 Um eine gleichberechtigte Teilhabe an der Gesellschaft von Menschen mit Behinderung zu ermöglichen, werden zunächst Daten zu vorhandenen Einschränkungen gebraucht. Erst wenn diese detailliert erhoben wurden, können Konzepte zur Beseitigung von Problemen entwickelt werden. Ein standardisiertes Erhebungsinstrument für alle Aspekte der Funktionsfähigkeit fehlte jedoch bisher.


2020 ◽  
Vol 10 (31) ◽  
pp. 87-95
Author(s):  
Nicole Maria Miyamoto Bettini ◽  
Fabiana Tomé Ramos ◽  
Priscila Masquetto Vieira de Almeida

A Organização Mundial da Saúde - OMS confirmou a circulação internacional do novo Coronavírus em janeiro de 2020, nomeando-o como COVID-19 e, declarando uma pandemia. É de extrema importância que durante a pandemia, os profissionais de saúde tenham acesso e conhecimento sobre o uso correto dos Equipamentos de Proteção Individual (EPIs) e suas indicações, tomando assim, as devidas precauções na prevenção de infecções. O presente estudo buscou identificar a padronização mundial quanto ao uso dos EPIs utilizados no atendimento a pacientes suspeitos e/ou confirmados de COVID-19 no Brasil, EUA, China, Espanha, Itália e demais países europeus. Os guidelines apresentam a padronização quanto ao uso dos EPIs utilizados no atendimento a suspeitos e/ou confirmados de COVID-19, indo ao encontro das recomendações fornecidas pela OMS. Até o momento, o uso de EPIs é sem dúvida a estratégia mais importante e eficaz para proteger os profissionais de saúde durante a assistência ao paciente com COVID-19.Descritores: Infecções por Coronavírus, Equipamento de Proteção Individual, Pessoal de Saúde, Enfermagem. Recommendations for personal protective equipment to combat COVID-19Abstract: The World Health Organization - WHO confirmed the international circulation of the new Coronavirus in January 2020, naming it as COVID-19 and declaring a pandemic. It is extremely important that during the pandemic, health professionals have access and knowledge about the correct use of Personal Protective Equipment (PPE) and its indications, thus taking appropriate precautions to prevent infections. The present study sought to identify the worldwide standardization regarding the use of PPE utilized to take care of suspected and confirmed patients with COVID-19 in Brazil, USA, China, Spain, Italy and other European countries. The guidelines present a standardization regarding the use of PPE utilized to take care of suspected and confirmed with COVID-19, in line with the recommendations provided by WHO. To date, the use of PPE is undoubtedly the most important and effective strategy to protect healthcare professionals during care for patients with COVID-19.Descriptors: Coronavirus Infections, Personal Protective Equipment, Health Personnel, Nursing. Recomendaciones para el equipo de protección personal para combatir COVID-19Resumen: La Organización Mundial de la Salud - La OMS confirmó la circulación internacional del nuevo Coronavirus en enero de 2020, nombrándolo COVID-19 y declarando una pandemia. Es extremadamente importante que durante la pandemia, los profesionales de la salud tengan acceso y conocimiento sobre el uso correcto del Equipo de Protección Personal (EPP) y sus indicaciones, tomando así las precauciones adecuadas para prevenir infecciones. El presente estudio buscó identificar la estandarización mundial con respecto al uso de EPP utilizado para atender a pacientes sospechosos y/o confirmados con COVID-19 en Brasil, Estados Unidos, China, España, Italia y otros países europeos. Las pautas presentan la estandarización con respecto al uso de EPP utilizado para cuidar COVID-19 sospechoso y/o confirmado, de acuerdo con las recomendaciones proporcionadas por la OMS. Hasta la fecha, el uso de EPP es, sin duda, la estrategia más importante y efectiva para proteger a los profesionales de la salud durante la atención de pacientes con COVID-19.Descriptores: Infecciones por Coronavirus, Equipo de Protección Personal, Personal de Salud, Enfermería.


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