scholarly journals Safety and Efficacy of a Novel Centrifugal Pump and Driving Devices of the OASSIST ECMO System: A Preclinical Evaluation in the Ovine Model

2021 ◽  
Vol 8 ◽  
Author(s):  
Sizhe Gao ◽  
Weining Wang ◽  
Jiachen Qi ◽  
Gang Liu ◽  
Jian Wang ◽  
...  
Keyword(s):  
Centrifugal Pump ◽  
Complete Blood Count ◽  
Ovine Model ◽  
Heparin Infusion ◽  
Preclinical Evaluation ◽  
Cardiopulmonary Support ◽  
Control Console ◽  
Pump Head ◽  
Rotary Speed ◽  
Clinical Conditions

Background: Extracorporeal membrane oxygenation (ECMO) provides cardiopulmonary support for critically ill patients. Portable ECMO devices can be applied in both in-hospital and out-of-hospital emergency conditions. We evaluated the safety and biocompatibility of a novel centrifugal pump and ECMO device of the OASSIST ECMO System (Jiangsu STMed Technologies Co., Suzhou, China) in a 168-h ovine ECMO model.Methods: The portable OASSIST ECMO system consists of the control console, the pump drive, and the disposable centrifugal pump. Ten healthy sheep were used to evaluate the OASSIST ECMO system. Five were supported on veno-venous ECMO and five on veno-arterial ECMO, each for 168 h. The systemic anticoagulation was achieved by continuous heparin infusion to maintain the activated clotting time (ACT) between 220 and 250 s. The rotary speed was set at 3,200–3,500 rpm. The ECMO configurations and ACT were recorded every 6 hours (h). The free hemoglobin (fHb), complete blood count, and coagulation action test were monitored, at the 6th h and every 24 h after the initiation of the ECMO. The dissection of the pump head and oxygenator were conducted to explore thrombosis.Results: Ten sheep successfully completed the study duration without device-related accidents. The pumps ran stably, and the ECMO flow ranged from 1.6 ± 0.1 to 2.0 ± 0.11 L/min in the V-V group, and from 1.8 ± 0.1 to 2.4 ± 0.14 L/min in the V-A group. The anticoagulation was well-performed. The ACT was maintained at 239.78 ± 36.31 s, no major bleeding or thrombosis was observed during the ECMO run or in the autopsy. 3/5 in the V-A group and 4/5 in the V-V group developed small thrombus in the bearing pedestal. No obvious thrombus formed in the oxygenator was observed. The hemolytic blood damage was not significant. The average fHb was 0.17 ± 0.12 g/L. Considering hemodilution, the hemoglobin, white blood cell, and platelets didn't reduce during the ECMO runs.Conclusions: The OASSIST ECMO system shows satisfactory safety and biocompatibility for the 168-h preclinical evaluation in the ovine model. The OASSIST ECMO system is promising to be applied in clinical conditions in the future.

Effect of semi-open impeller side clearance on centrifugal pump cavitation inception

2018 ◽  
Vol 1 (2) ◽  
pp. 24-39
Author(s):  
A. Farid ◽  
A. Abou El-Azm Aly ◽  
H. Abdallah
Keyword(s):  
Centrifugal Pump ◽  
Static Pressure ◽  
Rotation Speed ◽  
Centrifugal Pumps ◽  
Severe Condition ◽  
Cavitation Inception ◽  
Total Input ◽  
Input Pressure ◽  
Pump Head ◽  
Pump Pressure

Cavitation in pumps is the most severe condition that centrifugal pumps can work in and is leading to a loss in their performance.  Herein, the effect of semi-open centrifugal pump side clearance on the inception of pump cavitation has been investigated.  The input pump pressure has been changed from 80 to 16 kPa and the pump side clearance has been changed from 1 mm to 3 mm at a rotation speed of 1500 rpm. It has been shown that as the total input pressure decreased; the static pressure inside the impeller is reduced while the total pressure in streamwise direction has been reduced, also the pump head is constant with the reduction of the total input pressure until the cavitation is reached. Head is reduced due to cavitation inception; the head is reduced in the case of a closed impeller with a percent of 1.5% while it is reduced with a percent of 0.5% for pump side clearance of 1mm, both are at a pressure of 20 kPa.   Results also showed that the cavitation inception in the pump had been affected and delayed with the increase of the pump side clearance; the cavitation has been noticed to occur at approximate pressures of 20 kPa for side clearance of 1mm, 18 kPa for side clearances of 2mm and 16 kPa for 3mm.

scholarly journals ANALISA PERHITUNGAN DAYA POMPA SENTRIFUGAL DI GEDUNG UNIVERSITAS 17AGUSTUS 1945 JAKARTA

2019 ◽  
Vol 4 (1) ◽  
pp. 7-14
Author(s):  
M Fajri Hidayat ◽  
Nor Fajri
Keyword(s):  
Pump Power ◽  
Centrifugal Pump ◽  
Water Requirement ◽  
Clean Water ◽  
Pump Head ◽  
Pump Shaft ◽  
Specific Speed

AbstrakPompa adalah suatu alat atau mesin untuk memindahkan cairan dari satu tempat ketempat lain melalui suatu media perpipaan dengan cara menambahkan energi pada cairan yang dipindahkan dan berlangsung secara terus menerus. Pompa yang digunakan dalam analisa ini yaitu Pompa Sentrifugal yang terdapat di gedung Universitas 17 Agustus 1945 Jakarta. Tujuan dari analisa ini yaitu untuk mengetahui kebutuhan air pada gedung Universitas 17 Agustus 1945 Jakarta. Kebutuhan air pada gedung Universitas 17 Agustus 1945 Jakarta dihitung berdasarkan luas lantai gedung dan pemakaian setiap dosen, karyawan, mahasiswa, dan rektorat di Universitas 17 Agustus 1945 Jakarta. Hasil analisa di dapatkan total kebutuhan air bersih pada gedung Universitas 17 Agustus 1945 Jakarta adalah 1.7910 Liter/hari. Kapasitas pompa sebesar 0.06 m3/s. Head total pompa sebesar 31.99 m. Putaran poros pompa yaitu 1500 rpm. Daya pompa sebesar 0.817 kW. Kecepatan spesifik sebesar 48.51 rpm. Dari hasil analisa dapat dinyatakan bahwa Pompa Sentrifugal yang berada di gedung Universitas 17 Agustus 1945 Jakarta sudah layak untuk digunakan. Kata Kunci : Kebutuhan air, kapasitas pompa, pompa sentrifugal Abstract          A pump is a device or a machine to move liquids from one place to another via a piping medium by adding energy to the fluid that is moved and continuous. The pump used in this analysis is the Centrifugal Pump contained in the building University 17 August 1945 Jakarta. The purpose of this analysis is to determine the needs of water in the building University 17 August 1945 Jakarta. Water requirement at University building August 17, 1945 Jakarta is calculated based on building floor and usage of every lecturer, staff, student, and rectorate in University 17 August 1945 Jakarta. The result of the analysis in obtaining the total clean water requirement at the building University 17 August 1945 Jakarta is 1.7910 Liter / day. The pump capacity is 0.06 m3 / s. The total pump head is 31.99 m. The rotation of the pump shaft is 1500 rpm. The pump power is 0.817 kW. Specific speed of 48.51 rpm. The results of the analysis can be stated that the Centrifugal Pump located in the building University 17 August 1945 Jakarta is feasible to use. Keywords : Water requirement, pump capacity, centrifugal pump

Performance characteristics of the new Eurosets magnetically suspended centrifugal pump

Perfusion ◽  
2020 ◽  
pp. 026765912093199
Author(s):  
Denis Berdajs ◽  
Ludwig K von Segesser ◽  
Francesco Maisano ◽  
Guiseppina Milano ◽  
Enrico Ferrari
Keyword(s):  
Centrifugal Pump ◽  
Repeated Measurements ◽  
Hydrodynamic Performance ◽  
Membrane Oxygenator ◽  
Mean Flow ◽  
Biochemical Tests ◽  
Extracorporeal Membrane Oxygenator ◽  
Pump Head ◽  
Ventricular Assistance Device ◽  
Magnetically Suspended Centrifugal Pump

Objective: The aim was to evaluate the performance of a newly developed magnetically suspended centrifugal pump head intended for use as a ventricular assistance device with a newly developed extracorporeal membrane oxygenator setup. Methods: In an experimental setup, an extracorporeal membrane oxygenator circuit was established in three calves with a mean weight of 68.2 ± 2.0 kg. A magnetically levitated centrifugal pump was tested, along with a newly designed extracorporeal membrane oxygenator console, at three different flow ranges: (a) 0.0 to 5.2 L/min, (b) 0.0 to 7.1 L/min, and (c) 0.0 to 6.0 L/min. For each setup, the animals were supported by a circuit for 6 h. Blood samples were collected just before caridiopulmonary bypass (CPB) after 10 min on bypass and after 1, 2, 5, and 6 h of perfusion for hemolysis determination and biochemical tests. Values were recorded for blood pressure, mean flow, and pump rotational speed. Analysis of variance was used for repeated measurements. Results: Mean pump flows achieved during the three 6 h pump runs for the three pump heads studied were as follows: (a) flow range 0.0 to 5.2 L/min, 3.6 ± 1.5 L/min, (b) flow range 0.0 to 7.1 L/min, 4.9 ± 1.3 L/min, and (c) flow range 0.0 to 6.0 L/min, 3.8 ± 1.5 L/min. Blood trauma, evaluated by plasma hemoglobin and lactate dehydrogenase levels, did not help in detecting any significant hemolysis. Thrombocytes and white blood cell count profiles showed no significant differences between the groups at the end of the 6 h perfusion. At the end of testing, no clot deposition was found in the oxygenator, and there was no evidence of peripheral emboli. Conclusion: The results suggest that the newly developed magnetically suspended centrifugal pump head provides satisfactory hydrodynamic performance in an acute perfusion scenario without increasing hemolysis.

FLOW MEASUREMENT AT THE PUMP HEAD OF AN IMPLANTABLE CENTRIFUGAL PUMP WITH AN ULTRASONIC TRANSIT TIME (USTT) FLOWPROBE

ASAIO Journal ◽  
1996 ◽  
Vol 42 (2) ◽  
pp. 50
Author(s):  
H. Schima ◽  
L. Huber ◽  
H. Schmallegger ◽  
G. Wieselthaler ◽  
M. A. Rajek ◽  
...  
Keyword(s):  
Centrifugal Pump ◽  
Transit Time ◽  
Flow Measurement ◽  
Pump Head

Effect of Surfactant Additives on Centrifugal Pump Performance

2003 ◽  
Author(s):  
Satoshi Ogata ◽  
Keizo Watanabe ◽  
Asano Kimura
Keyword(s):  
Centrifugal Pump ◽  
Surfactant Concentration ◽  
Tap Water ◽  
Maximum Flow ◽  
Pump Efficiency ◽  
Optimal Temperature ◽  
Pump Performance ◽  
Surfactant Solutions ◽  
Pump Head ◽  
Shaft Power

Performance of a centrifugal pump when handling surfactant solutions was measured experimentally. The effects of the concentration and temperature of surfactant solutions on pump performance were investigated. It was clarified that the pump efficiency with surfactant solutions was higher than that with tap water, and increased with an increase of surfactant concentration. The value of maximum flow rate of the pump also increased. The total pump head increased with an increase in the surfactant concentration, however, the shaft power decreased with a decrease in the rotational speed of the impeller. The pump efficiency is dependent on the surfactant temperature, and there is an optimal temperature which maximizes the efficiency.

Numerical and Experimental Investigations of the Cavitating Flow in a Centrifugal Pump Impeller

2002 ◽  
Author(s):  
Moritz Frobenius ◽  
Rudolf Schilling ◽  
Jens Friedrichs ◽  
Gu¨nter Kosyna
Keyword(s):  
Numerical Simulations ◽  
Centrifugal Pump ◽  
Bubble Dynamics ◽  
Cavitating Flow ◽  
Experimental Investigations ◽  
Pump Impeller ◽  
Pump Head ◽  
Flow Through ◽  
Technical University ◽  
Centrifugal Pump Impeller

This paper presents numerical simulations and experimental investigations of the cavitating flow through a centrifugal pump impeller of low specific speed. The experimental research was carried out at the Pfleiderer-Institute of the Technical University of Braunschweig, while the numerical simulations were performed at the Institute for Hydraulic Machinery and Plants at the Technical University of Munich (LHM). The cavitation model used is based on bubble dynamics and is able to describe the complicated and transient growth and collapse of the cavitation bubbles. The model has been implemented in the 3D CFD-code CNS3D developed at the LHM. The CNS3D-code has been applied to simulate the cavitating flow through a centrifugal pump impeller. The computed pump head, incipient NPSH and three-percent head drop are compared to the experimental data. Also the pressure distributions measured on the blades are compared with the computed ones. Finally, the numerically investigated void fraction distributions are shown in comparison with pictures of the cavitation zones on the blade.

scholarly journals Effect of the staggered impeller on reducing unsteady pressure pulsations of a centrifugal pump

2021 ◽  
Author(s):  
Ning Zhang ◽  
Junxian Jiang ◽  
Xiaokai Liu ◽  
Bo Gao
Keyword(s):  
Centrifugal Pump ◽  
Internal Flow ◽  
Simulation Method ◽  
Low Noise ◽  
Stable Operation ◽  
Pump Efficiency ◽  
Pressure Pulsations ◽  
Pump Design ◽  
Pump Head ◽  
Rotor Stator Interaction

Abstract High pressure pulsations excited by rotor stator interaction is always focused in pumps, especially for its control considering the stable operation. In the current research, a special staggered impeller is proposed to reduce intense pressure pulsations of a centrifugal pump with ns=69 based on alleviating rotor stator interaction. The numerical simulation method is conducted to illustrate the influence of staggered impeller on the pump performance and pressure pulsations, and three typical flow rates (0.8ФN-1.2ФN) are simulated. Results show that the staggered impeller will lead to the pump head increasing, and at the design working condition, the increment reaches about 3% compared with the original impeller. Meanwhile, the pump efficiency is little affected by the staggered impeller, which is almost identical with the original impeller. From comparison of pressure spectra at twenty monitoring points around the impeller outlet, it is validated that the staggered impeller contributes significantly to decreasing pressure pulsations at the concerned working conditions. At the blade passing frequency, the averaged reduction of twenty points reaches 89% by using the staggered impeller at 1.0ФN. The reduction reaches to 90%, 80% at 0.8ФN, 1.2ФN respectively. Caused by the rib within the staggered impeller, the internal flow field in the blade channel will be affected. Finally, it is concluded that the proposed staggered impeller surely has a significant effect on alleviating intense pressure pulsation of the model pump, which is very promising during the low noise pump design considering its feasibility for manufacturing.

scholarly journals Effect of Blade Thickness on Internal Flow and Performance of a Plastic Centrifugal Pump

Machines ◽  
2022 ◽  
Vol 10 (1) ◽  
pp. 61
Author(s):  
Zhenfa Xu ◽  
Fanyu Kong ◽  
Lingfeng Tang ◽  
Mingwei Liu ◽  
Jiaqiong Wang ◽  
...  
Keyword(s):  
Centrifugal Pump ◽  
Variable Thickness ◽  
Internal Flow ◽  
Constant Thickness ◽  
Element Analysis ◽  
Pump Performance ◽  
Blade Thickness ◽  
The Finite Element Analysis ◽  
Pump Head ◽  
And Performance

Blade thickness is an essential parameter of the impeller, which has significant effects on the pump performance. The plastic pump generally adopts thick blade due to low strength of plastic. The effects of blade thickness on the internal flow and performance of a plastic centrifugal pump were discussed based on the numerical methods. Two kinds of blade profile, the constant thickness blade (CTB) and the variable thickness blade (VTB), were investigated. The results indicated that, for the CTB, when the blade thickness was less than 6 mm, the pump performance did not change significantly. When the blade thickness exceeded 6 mm, the pump head and efficiency decreased rapidly. The pump head and efficiency of CTB 10 decreased by 42.2% and 30% compared with CTB 4, respectively. For the VTB, with blade thickness in a certain range (6 mm–14 mm), the pump performance changed slightly with the increased of trailing edge thickness. The minimum blade thickness of the plastic centrifugal pump should be 4 mm based on the finite element analysis. A variable thickness blade (VTB 4-8-4) with the maximum thickness located at 60% chord length was proposed to improve the pump performance, and its efficiency was 1.67% higher than that of the CTB 4 impeller.

Flow loss analysis of a two-stage axially split centrifugal pump with double inlet under different channel designs

2019 ◽  
Vol 233 (15) ◽  
pp. 5316-5328 ◽  
Author(s):  
Majeed Koranteng Osman ◽  
Wenjie Wang ◽  
Jianping Yuan ◽  
Jiantao Zhao ◽  
Yiyun Wang ◽  
...  
Keyword(s):  
Centrifugal Pump ◽  
Flow Characteristics ◽  
Water Diversion ◽  
Centrifugal Pumps ◽  
Loss Analysis ◽  
Flow Losses ◽  
Water Pumping ◽  
Pumping Stations ◽  
Pump Head ◽  
Flow Loss

The double-stage axially split centrifugal pump is widely used in water diversion and water pumping stations due to their ability to deliver at high heads and large flow rate for long running hours. Their flow characteristics can be greatly influenced by the geometry of the channels between the stages, which is a prominent place for irreversible loss to occur. Numerical investigations were extensively carried out and a comparison was drawn between two multistage axially split centrifugal pumps, with different channel designs between its stages. The reliability of the numerical model was confirmed after a good agreement existed between numerical results and the experiments. Subsequently, entropy generation terms were used to evaluate turbulence dissipation to characterize the flow losses. The modified channels had a great effect on reducing swirl near the impeller eye, thereby improving pump head by 12.5% and efficiency by 4.98% at the design condition. They however induced flow impact, causing an unusual separation, which generated high turbulence dissipation at the blade surfaces. The channels and second stage impeller were identified as major areas for selective optimization since their turbulence dissipation was dominant. Consequently, entropy production analysis with computational fluid dynamics could be relied upon to reveal the loss locations for selective optimization in centrifugal pumps.

Analysis of Centrifugal Pump Performing Under Two-Phase Flow Using Bleeding System

2001 ◽  
Author(s):  
M. A. Zaher
Keyword(s):  
Multiphase Flow ◽  
Centrifugal Pump ◽  
Fluid Model ◽  
Energy Requirement ◽  
Two Phase ◽  
Pump Test ◽  
Pump Head ◽  
Two Fluid Model ◽  
Specific Energy Requirement ◽  
Two Fluid

Abstract A one dimensional two fluid model is used to study the performance of a centrifugal pump. Pumping of two-phase products in oil/geothermal industry offered a special multiphase pump. Test with different suction void fraction was used to predict the two-phase pump head data for two scales of pumps. With the new arrangement of bleeding and correct impeller design, a radical solution is offered to handle a multiphase flow. The physical mechanism responsible for transporting multiphase flow on efficiency, specific energy requirement and flow rate were also investigated.

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