scholarly journals Case Report: Infantile Bullous Pemphigoid: Triggering by COVID-19 Is Speculative

2021 ◽  
Vol 8 ◽  
Author(s):  
Anna Rosińska-Więckowicz ◽  
Magdalena Jałowska ◽  
Monika Bowszyc-Dmochowska ◽  
Marian Dmochowski

Bullous pemphigoid (BP) is a cutaneous disease triggered by numerous stimuli, where genetic milieu-influenced autoimmunity to hemidesmosomal proteins, namely, BP180 and/or BP230 initiate an inflammation leading to dermal-epidermal junction (DEJ) enzymatic pathological remodelling. Here, to the best of our knowledge, we present the first case of an infantile BP apparently triggered by COVID-19. BP should be included in differential diagnosis of infantile rashes showing blisters or vesicles or both as well as their prodromal and evolutionary lesions. Possible triggers, such as coronavirus disease 2019 (COVID-19), of BP in infancy should be identified and properly dealt with.

2013 ◽  
Vol 2013 ◽  
pp. 1-4
Author(s):  
Brian Cervenka ◽  
Brenda Villegas ◽  
Uttam Sinha

Solitary fibrous tumor (SFT) is a rare mesenchymal neoplasm that can present essentially anywhere in the body. Presentations in the hypopharynx are extremely rare with only two previous cases reported. We report the first case of postcricoid SFT occurring in a 58-year-old male requiring a microsuspension laryngoscopy excision following an unsuccessful transoral robotic attempt. The excision was uneventful, and the patient is currently without recurrence. Current management strategies of the hypopharyngeal SFT, the unique differential diagnosis, and challenges in surgical approaches in the postcricoid region are discussed.


2018 ◽  
Vol 21 (2) ◽  
pp. 107-111 ◽  
Author(s):  
Bowen Jiang ◽  
Harry Mushlin ◽  
Lei Zhang ◽  
Aaron W. James ◽  
Alan R. Cohen

Scalp and calvarial masses are common in children and the differential diagnosis is broad. The authors recently cared for a child with an unusual fibro-osseous lesion of the temporal bone that has previously not been described in the pediatric neurosurgery literature. A 10-year-old girl presented with a firm, slowly enlarging protuberant mass arising from the squamous suture of the temporal bone without intracranial extension. The mass was removed en bloc through a temporal craniectomy and cranioplasty was performed. The patient had a smooth postoperative course. Histological examination showed multiple oval osseous islands dispersed throughout a bland fibrous stroma. The pathological diagnosis was “Bullough’s bump,” a rare, benign fibro-osseous neoplasm first described in 1999, and only 8 reported cases appear in the literature. Here the authors report the first case of Bullough’s bump in a child.


2015 ◽  
Vol 19 (2) ◽  
pp. 153-155 ◽  
Author(s):  
Waleed Al-Salhi ◽  
Ru'aa Alharithy

Background Pemphigoid nodularis is a rare clinical variant of bullous pemphigoid characterized by overlapping clinical features of both prurigo nodularis lesions and bullous pemphigoid blisters. The condition appears to be more common in females and is often resistant to treatment. Objective To raise awareness of this rare variant of bullous pemphigoid. Methods Case report. Results and Conclusion Dermatologists should include this variant in differential diagnosis of prurigo nodularis because early recognition can lead to an effective treatment for the prurigo component.


2016 ◽  
Vol 2016 ◽  
pp. 1-3 ◽  
Author(s):  
M. I. Montenovo ◽  
F. G. Jalikis ◽  
M. Yeh ◽  
J. D. Reyes

We report a case of hepatic adenoma progression to carcinoma in the setting of hepatoportal sclerosis in an HIV+ patient and provide a review of the scarce literature regarding hepatoportal sclerosis in HIV patients. We describe the clinical presentation, diagnostic workup, and management. This is the first case report in the literature of progression of hepatic adenoma to carcinoma in hepatoportal sclerosis in an HIV patient. This case also highlights the broad differential diagnosis that should always be included in the study of any liver disease in this patient population, including the performance of invasive and aggressive tests to arrive at the final diagnosis.


2019 ◽  
Vol 12 ◽  
pp. 117954761982868 ◽  
Author(s):  
Muhammad Ishaq Ghauri ◽  
Syeda Beenish Bareeqa ◽  
Amir Riaz ◽  
Ajeet Kumar

Introduction: Iatrogenic or physician-induced hypervitaminosis D is a rare cause of persistent vomiting. To the best of our knowledge, this is the first case report on iatrogenic hypervitaminosis D presenting with persistent vomiting in Pakistan. Case Report: We report a rare case of continual vomiting for 15 days in a 48-year-old woman of Pakistani descent. She was a known case of diabetes mellitus for 8 years, which was well controlled at the time of presentation. Conclusions: The correct diagnosis of our patient was based on clinical suspicion, appropriate lab tests, and deliberation of the differential diagnosis. It is important to consider hypervitaminosis D as a cause of persistent vomiting if no other obvious is apparent.


Cephalalgia ◽  
2010 ◽  
Vol 30 (11) ◽  
pp. 1400-1402 ◽  
Author(s):  
Chong Yoon Park ◽  
Kyung Soo Kim

Background: Pneumoceles of the paranasal sinuses are a very rare condition; characterized by a distended air-filled paranasal sinus extending beyond the margins of the paranasal bone, with bony defects and extension of air into the surrounding soft tissues. Also, spontaneous pneumo-cephalus is a rare condition which represented only 0.6% in the largest reported series of pneumocephalus. Although pneumocephalus caused by sinogenic origins, such as osteoma, has been reported, spontaneous pneumocephalus has not been reported as a complication associated with pneumocele of the frontal sinus. Methods: We report a case of spontaneous pneumocephalus associated with a pneumocele involving the frontal sinus which presented as acute severe headache. Results: To the best of our knowledge, this is the first case report in literature reporting spontaneous pneumocephalus in association with pneumocele of the frontal sinus. Conclusions: Although pneumocele of the frontal sinus is a very rare condition, it can develop into spontaneous pneumocephalus, and thus it needs to be included in the differential diagnosis of acute severe headache.


2020 ◽  
Vol 4 (2) ◽  
pp. 143
Author(s):  
Naeha Gupta ◽  
Payvand Kamrani ◽  
Nektarios Lountzis ◽  
Richard McClain

Reactive angioendotheliomatosis (RAE) is a rare, typically self-limiting, angioproliferative disease that is commonly seen in patients with a variety of inflammatory and systemic diseases. RAE can clinically present as ulcerated, single or multifocal, violaceous papules or plaques. We report a case of a 59-year-old male with a complicated cardiac history who presented with biopsy-proven RAE on the thigh. The differential diagnosis of RAE can include Kaposi sarcoma and angiosarcoma, as well as other non-malignant cutaneous disease. These diagnoses must be excluded before correctly diagnosing and treating RAE. We review the common presentation of RAE along with criteria to exclude other possible diagnoses that can resemble RAE. 


2017 ◽  
Vol 4 (5) ◽  
pp. 1793
Author(s):  
Rajashekhar T. Patil ◽  
Sandesh V. Parelkar ◽  
Beejal Sanghvi

Hydatidosis is an endemic disease caused by Echinococcus granulosus. Humans are accidental intermediate hosts. In children, it affects the lung in 64% of cases and the liver in 28%. Renal involvement is uncommon (2-4%). We operated 7 years old girl with renal and hepatic hydatidosis laparoscopically. Hydatid cyst should be kept as one of differential diagnosis while managing cystic disease of any organ in the body. To the best of our knowledge this is the first case of renal hydatidosis with hepatic hydatidosis that has been managed laparoscopically. Laparoscopic surgery is safe and efficacious in managing multiorgan hydatid disease in children.


2012 ◽  
Vol 2012 ◽  
pp. 1-3
Author(s):  
Jennifer Hsu ◽  
Brian G. Mohney

Periocular tumors are common in infancy. The most common periocular tumors are capillary hemangiomas, which are present in 1-2% of newborns and develop in 10%–12% of children by the age of 1 year old. Deep capillary hemangiomas may be more challenging to diagnose than superficial capillary hemangiomas and can be confused with other orbital lesions. Deep orbital hemangiomas can mimic teratoma, lymphangioma, rhabdomyosarcoma, metastatic neuroblastoma, and granulocytic sarcoma. In this paper, we describe 2 pediatric cases where previously diagnosed dermoid cyst and dacrocystocele were found to be capillary hemangiomas upon biopsy. Approaches to distinguish capillary hemangiomas from other periocular tumors are further discussed. To our knowledge, this is the first case report of periocular hemangiomas imitating a dermoid cyst and a dacrocystocele. These cases emphasize the importance of including infantile hemangiomas in the differential diagnosis of subcutaneous periocular abnormalities.


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