scholarly journals Management of Epileptic Seizures in Disorders of Consciousness: An International Survey

2022 ◽  
Vol 12 ◽  
Author(s):  
Marie-Michèle Briand ◽  
Nicolas Lejeune ◽  
Nathan Zasler ◽  
Rita Formisano ◽  
Olivier Bodart ◽  
...  
Keyword(s):  
Online Survey ◽  
Brain Injuries ◽  
Guideline Development ◽  
Drug Effects ◽  
Epileptic Seizures ◽  
Final Analysis ◽  
Disorders Of Consciousness ◽  
Severe Injuries ◽  
Cross Sectional ◽  
Treatment Standard

Epileptic seizures/post-traumatic epilepsy (ES/PTE) are frequent in persons with brain injuries, particularly for patients with more severe injuries including ones that result in disorders of consciousness (DoC). Surprisingly, there are currently no best practice guidelines for assessment or management of ES in persons with DoC. This study aimed to identify clinician attitudes toward epilepsy prophylaxis, diagnosis and treatment in patients with DoC as well as current practice in regards to the use of amantadine in these individuals. A cross-sectional online survey was sent to members of the International Brain Injury Association (IBIA). Fifty physician responses were included in the final analysis. Withdrawal of antiepileptic drug/anti-seizure medications (AED/ASM) therapy was guided by the absence of evidence of clinical seizure whether or not the AED/ASM was given prophylactically or for actual seizure/epilepsy treatment. Standard EEG was the most frequent diagnostic method utilized. The majority of respondents ordered an EEG if there were concerns regarding lack of neurological progress. AED/ASM prescription was reported to be triggered by the first clinically evident seizure with levetiracetam being the AED/ASM of choice. Amantadine was frequently prescribed although less so in patients with epilepsy and/or EEG based epileptic abnormalities. A minority of respondents reported an association between amantadine and seizure. Longitudinal studies on epilepsy management, epilepsy impact on neurologic prognosis, as well as potential drug effects on seizure risk in persons with DoC appear warranted with the goal of pushing guideline development forward and improving clinical assessment and management of seizures in this unique, albeit challenging, population.

scholarly journals Physicians’ Knowledge, Attitude and Practice of Generic Substitution in China: A Cross-Sectional Online Survey

2021 ◽  
Vol 18 (15) ◽  
pp. 7749
Author(s):  
Mingyue Zhao ◽  
Lingyi Zhang ◽  
Zhitong Feng ◽  
Yu Fang
Keyword(s):  
Online Survey ◽  
Generic Substitution ◽  
Generic Drugs ◽  
Final Analysis ◽  
Generic Medicine ◽  
Generic Medicines ◽  
Online Questionnaire ◽  
Cross Sectional ◽  
Ordered Logistic Regression ◽  
Tertiary Hospitals

The purpose of this study is to investigate physicians’ knowledge, attitudes and practice of generic medicine substitutions in China. We conducted a cross-sectional online questionnaire survey on physicians from secondary or tertiary hospitals in China from 2020 December to 2021 April. Descriptive statistical and ordered logistic regression were used for analysis. A total of 1225 physicians were included in the final analysis, and only 330 (26.94%) of them scored 4 or above in the knowledge part, which means that the physicians have a good knowledge of generic substitutions. Of the total, 586 (47.83%) agreed or strongly agreed that generic drugs could be substituted for originator drugs and 585 (47.75%) always or often prescribed generic medicines. The percentage of physicians with a positive attitude toward or that practice prescribing generic medicine is below 50%, which needs to be improved in China. Physicians’ knowledge, their attitude toward generic substitution, if familiar with the policy of generic substitution, and incentives for prescribing generic medicines are influencing factors for the practice of generic substitution. Our studies show that the practice of generic substitution by physicians could be improved by several measures in China. We suggested that the physicians should be taught more about the bulk-buy policy and the generic-originator equivalence evaluation policy. Moreover, government incentives to promote generic substitution should be established. Our study also suggested that physicians with less working experience and female physicians should learn more about generic substitution.

scholarly journals Infrastructural and Human Factors Affecting Safety Outcomes of Cyclists

2018 ◽  
Vol 10 (2) ◽  
pp. 299 ◽  
Author(s):  
Sergio Useche ◽  
Luis Montoro ◽  
Francisco Alonso ◽  
Oscar Oviedo-Trespalacios
Keyword(s):  
Human Factors ◽  
Online Survey ◽  
Demographic Data ◽  
Cross Sectional Study ◽  
User Characteristics ◽  
Severe Injuries ◽  
Related Factors ◽  
Cross Sectional ◽  
Road Crashes ◽  
Safety Outcomes

The increasing number of registered road crashes involving cyclists during the last decade and the high proportion of road crashes resulting in severe injuries and fatalities among cyclists constitutes a global issue for community health, urban development and sustainability. Nowadays, the incidence of many risk factors for road crashes of cyclists remains largely unexplained. Given the importance of this issue, the present study has been conducted with the aim of determining relationships between infrastructural, human factors and safety outcomes of cyclists. Objectives: This study aimed, first, to examine the relationship between key infrastructural and human factors present in cycling, bicycle-user characteristics and their self-reported experience with road crashes. And second, to determine whether a set of key infrastructural and human factors may predict their self-reported road crashes. Methods: For this cross-sectional study, a total of 1064 cyclists (38.8% women, 61.2% men; M = 32.8 years of age) from 20 different countries across Europe, South America and North America, participated in an online survey composed of four sections: demographic data and cycling-related factors, human factors, perceptions on infrastructural factors and road crashes suffered. Results: The results of this study showed significant associations between human factors, infrastructural conditions and self-reported road crashes. Also, a logistic regression model found that self-reported road crashes of cyclists could be predicted through variables such as age, riding intensity, risky behaviours and problematic user/infrastructure interactions. Conclusions: The results of this study suggest that self-reported road crashes of cyclists are influenced by features related to the user and their interaction with infrastructural characteristics of the road.

COVID-19 complications and entrepreneurial intention among the entrepreneurs of Pakistan: evidence from the second wave of the pandemic

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Bahadur Ali Soomro
Keyword(s):  
Structural Equation ◽  
Online Survey ◽  
Final Analysis ◽  
Entrepreneurial Intention ◽  
Equation Model ◽  
Cross Sectional ◽  
Content Type ◽  
Negative Effect ◽  
The Government ◽  
Second Wave

Purpose At present, nearly the whole globe is facing a severe threat of COVID-19. This study aims to examine the COVID-19 complications and entrepreneurial intention among the entrepreneurs of Pakistan. Design/methodology/approach The study used a deductive approach. An online survey is conducted to collect cross-sectional data from entrepreneurs of Pakistan. Convenience sampling is applied to target the respondents. In total, 278 usable answers proceed for final analysis. The structural equation model (SEM) is used to infer the results. Findings The findings of the study highlight a significant negative effect of fear of COVID-19 (FO19), perceived susceptibility (PSU) and perceived severity (PSE) on entrepreneurial intention (EI) among the entrepreneurs. Practical implications The study would provide the guidelines for policymakers and planners to combat the barriers of fear, PSU and PSE during a pandemic. The findings of the second wave of COVID-19 may provide a warning to the government to take preventive measures to face the severe effect of the pandemic. Finally, the outcomes of the study may enrich the depth of COVID-19 literature globally. Originality/value This study is the first study highlighting factors such as fear, PSU and PSE toward EI in COVID-19 second wave.

scholarly journals COVID-19 misinformation: mere harmless delusions or much more? A knowledge and attitude cross-sectional study among the general public residing in Jordan

2020 ◽  
Author(s):  
Malik Sallam ◽  
Deema Dababseh ◽  
Alaa Yaseen ◽  
Ayat Al-Haidar ◽  
Duaa Taim ◽  
...  
Keyword(s):  
General Public ◽  
Online Survey ◽  
Psychological Impact ◽  
Final Analysis ◽  
Anxiety Level ◽  
Accurate Information ◽  
Sources Of Information ◽  
Monthly Income ◽  
Cross Sectional ◽  
History Of

Abstract Since the emergence of the recent coronavirus disease 2019 (COVID-19) and its spread as a pandemic, media was teeming with misinformation that led to psychologic, social and economic consequences among the global public. Probing knowledge and anxiety regarding this novel infectious disease is necessary to identify gaps and sources of misinformation which can help public health efforts to design and implement more focused interventional measures. The aim of this study was to evaluate the knowledge, attitude and effects of misinformation about COVID-19 on anxiety level among the general public residing in Jordan. An online survey was used that targeted people aged 18 and above and residing in Jordan. The questionnaire included items on the following: demographic characteristics of the participants, knowledge about COVID-19, anxiety level and misconceptions regarding the origin of the pandemic. The total number of participants included in final analysis was 3150. The study population was predominantly females (76.0%), with mean age of 31 years. The overall knowledge of COVID-19 was satisfactory. Older age, male gender, lower monthly income and educational levels, smoking and history of chronic disease were associated with perceiving COVID-19 as a very dangerous disease. Variables that were associated with a higher anxiety level during the pandemic included: lower monthly income and educational level, residence outside the capital (Amman) and history of smoking. Misinformation about the origin of the pandemic (being part of a conspiracy, biologic warfare and the 5G networks role) was also associated with higher anxiety and lower knowledge about the disease. Social media platforms, TV and news releases were the most common sources of information about the pandemic. The study showed the potential harmful effects of misinformation on the general public and emphasized the need to meticulously deliver timely and accurate information about the pandemic to lessen the health, social and psychological impact of the disease.

scholarly journals The role of community pharmacists in immunisation: a national cross-sectional study

2021 ◽  
Author(s):  
Nikolaus Lindner ◽  
Martin Riesenhuber ◽  
Thomas Müller-Uri ◽  
Anita Elaine Weidmann
Keyword(s):  
Online Survey ◽  
Theoretical Domains Framework ◽  
Community Pharmacists ◽  
Final Analysis ◽  
Cross Sectional Study ◽  
Patient Contact ◽  
Cross Sectional ◽  
Ethical Approval ◽  
The Right

AbstractBackground Austrian pharmacists are not authorised to administer immunisations, and evidence about their willingness to immunise is lacking. Aim The aim of this study is to investigate Austrian community pharmacists’ willingness to administer immunisations in the future. Method This study is designed as a cross-sectional online survey based on the theoretical domains framework (TDF). The validated and piloted questionnaire obtained ethical approval by Robert Gordon University. Outcome measures included pharmacists’ willingness to immunise, service requirements, barriers and education needs. Results The questionnaire was sent out to 3086 community pharmacists of which 380 responses were included in the final analysis (12.3%). Willingness to administer immunisations after appropriate training and legislative regulation was stated by 82.6% (n = 314) of participants. It was demonstrated that pharmacists willing to immunise were significantly younger than their counterpart (38 [IQR 31–49] years vs. 45 [IQR 37.5–54] years; OR 1.06; 1.03–1.09, 95% CI; p < 0.001). ‘Legal liability’ was considered the most critical barrier to service implementation, ‘seeing blood’ and ‘close patient contact’ as least critical. Pharmacists not willing to immunise showed a higher probability to evaluate personnel resources (OR 2.98; 1.35–6.58, 95% CI; p = 0.007), close patient contact (OR 2.79; 1.46–5.34, 95% CI; p = 0.002) and management of side effects (OR 2.62; 1.21–5.67, 95% CI; p = 0.015) as (highly) critical. The majority assessed the ‘right timing for training’ to be after the foundation training with a 2-yearly renewal. Conclusion Austrian community pharmacists show a strong willingness to administer immunisations while highlighting important requirements and barriers towards service implementation.

Examining the intention to stay home due to COVID-19: a pandemic's second wave outlook

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Bahadur Ali Soomro ◽  
Naimatullah Shah
Keyword(s):  
Structural Equation ◽  
Online Survey ◽  
Final Analysis ◽  
Equation Model ◽  
Intention To Stay ◽  
Cross Sectional ◽  
Content Type ◽  
The Government ◽  
Second Wave ◽  
At Home

PurposeAt present, almost the whole globe is facing a severe threat of coronavirus disease 2019 (COVID-19). The present study examines the intention to stay home due to COVID-19 during a second wave of the pandemic.Design/methodology/approachThe study employed a deductive approach based on cross-sectional data. An online survey is conducted from citizens of Pakistan. A convenience sampling is applied to target the respondents. In total, 238 useable responses proceed for final analysis. The structural equation model (SEM) is used to infer the results.FindingsThe findings of the study highlight a positive and significant effect of fear of COVID-19, attitudes to stay at home behaviour (AtSHB), knowledge about COVID-19 (Ka19) and health consciousness (HC) on the intention to stay at home (ItSAH).Practical implicationsThe study would provide the guidelines to policymakers and planners to develop the policies which may establish the individual's ItSAH. This strategy would restrict the spread of COVID-19. The government should also formulate the plannings to reduce the fear about COVID-19 and health concerns to combat the pandemic. The government should launch awareness programs regarding the spread and cure of COVID-19.Originality/valueThis study is the first study which highlights the factors such as fear, HC, attitudes and knowledge towards ItSAH. The study may be unique in the COVID-19 perspective, particularly in the Pakistani context.

scholarly journals Coma recovery scale: Key clinical tool ignored enough in disorders of consciousness

2021 ◽  
Vol 12 ◽  
pp. 93
Author(s):  
Jitender Chaturvedi ◽  
Shiv Kumar Mudgal ◽  
Tejas Venkataram ◽  
Priyanka Gupta ◽  
Nishant Goyal ◽  
...  
Keyword(s):  
Multivariate Analysis ◽  
Online Survey ◽  
Vegetative State ◽  
Minimally Conscious State ◽  
Diagnostic Errors ◽  
Demographic Variables ◽  
Disorders Of Consciousness ◽  
Clinical Tool ◽  
Optimal Care ◽  
Cross Sectional

Background: Disorders of consciousness (DoC) includes coma, vegetative state (VS), minimally conscious state (MCS), and emergence from the MCS. Aneurysmal rupture with high-grade SAH, traumatic brain injury, and neoplastic brain lesions are some of the frequent pathologies leading to DoC. The diagnostic errors among these DoC are as high as ranging from 25% to 45%, with a probable error in the conclusion of patients’ state, treatment choice, end-of-life decision-making, and prognosis. Some studies also reported that 37–43% of patients were misdiagnosed in VS while demonstrating signs of awareness. Despite its wide acceptance, Coma Recovery Scale-Revised (CRS-r) remained underused or inappropriately utilized, which may lead to substandard or unprofessional patient care. Literature is rare on the knowledge of CRS-r among physicians published from India and across the globe. Therefore, we carried out the present study to ascertain physicians’ knowledge on CRS-r and raise awareness about its justifiable clinical utilization. We also explored the factors associated with this perceived level of experience among participants and recommend frequent physicians’ training for care of patients with DoC. Methods: An institution-based cross-sectional online survey was conducted from June 8 to July 7, 2020, among Ninety-six physicians recruited using a convenient sampling technique. Twenty-item, validated, reliable, and a pilot-tested questionnaire was used to assess the knowledge regarding CRS-r and collect socio-demographic variables. The analysis was performed using the Statistical Package for the Social Sciences version 23. Bivariate and multivariate logistic regression analyses were employed to assess the association of participants’ socio-demographic variables and their parent department of work with the knowledge. P < 0.05 was considered statistically significant in the multivariate analysis. Results: A total of Ninety-six participants were included in the analysis, and only 33.3% of them were found to have adequate knowledge of CRS-r. Multivariate analysis revealed that age (adjusted odds ratio [AOR] = 31.66; 95% CI: 6.25–160.36), gender (AOR = 44.16; 95% CI: 7.43–268.23), and parent department of working (AOR = 0.148; 95% CI: 0.06–0.39) were significantly associated with the knowledge. Conclusion: Knowledge of the physicians on CRS-r is found to be exceptionally low. It has a strong tendency to adversely affect patients’ optimal care with disorders of consciousness (DoC). Therefore, it is crucial to expand physicians’ knowledge and awareness regarding CRS-r to adequately screen patients with DoC.

scholarly journals Does Students’ Home Zip Code Relate to Food Insecurity on Campus? Implications of Home Demographics on Food Insecurity in College

2021 ◽  
Vol 5 (Supplement_2) ◽  
pp. 178-178
Author(s):  
Abigail Sarna ◽  
Jesse Stabile Morrell
Keyword(s):  
College Students ◽  
Food Security ◽  
Food Insecurity ◽  
Online Survey ◽  
Census Data ◽  
Final Analysis ◽  
Cross Sectional ◽  
Food Security Status ◽  
Security Index ◽  
Zip Code

Abstract Objectives To explore the relationship between students’ home zip code demographics and their food security status at a midsized, northeastern university. Methods Data were collected between 2018–2020 from the College Health and Nutrition Assessment Survey, an ongoing, cross sectional study at a midsized, public, northeastern university. As part of an online survey (Qualtrics) offered during the 3rd or 4th week of the semester, students completed the 6-item USDA Food Insecurity Questionnaire and provided the zip code associated with their primary residence prior to attending college. Students’ self-reported answers were used to categorize current food security status: food secure, low food secure, or very low food secure. A food security index was created from 13 unique sets of US Census data associated with zip codes. Each zip code was scored by sextiles for each census demographic and summed; final index values were assigned to each reported zip code and ranged from high to low risk of food insecurity (13–78). Results After exclusion of missing data, 687 students were included in the final analysis. The sample of predominantly female (62.0%), white (93.1%), first year (47.7%), and reported a zip code from the home state of the institution (39.9%). The mean food security index (±SD) of reported zip codes was 45.3 ± 8.9. In all, 18.8% reported food insecurity, (5.5% very low food security and 13.2% low food security), and 81.2% reported food security or marginal food security. Food insecurity was highest (21.8%) in students from zip codes most at risk for food insecurity based on the index, however, not significantly different from students from zip codes with the most food secure index score (18.8%). Conclusions Food insecurity among college students has been previously linked to poorer health, grades, and academic retention. More work is needed to elucidate the role of students’ prior place of residence to identify those at greatest risk of experiencing food insecurity on campus. Funding Sources The New Hampshire Agricultural Experiment Station and USDA National Institute of Food and Agricultural Hatch Project 1010738.

scholarly journals Attitude towards Zika among frontline physicians in a dengue-endemic country: A preliminary cross-sectional study in Indonesia

Narra J ◽  
2021 ◽  
Vol 1 (1) ◽  
Author(s):  
Amanda Yufika ◽  
Samsul Anwar ◽  
Reza Maulana ◽  
Nur Wahyuniati ◽  
Rizki R. Ramadana ◽  
...  
Keyword(s):  
Online Survey ◽  
Final Analysis ◽  
Cross Sectional Study ◽  
Endemic Country ◽  
Cross Sectional ◽  
Medical Experience ◽  
Education Professional ◽  
Strategic Initiatives ◽  
Adjusted Model ◽  
Good Attitude

In dengue-endemic countries such as Indonesia, Zika may be misdiagnosed as dengue, leading to underestimates of Zika disease and less foreknowledge of pregnancy-related complications such as microcephaly. Objective: To assess the attitudes of frontline physicians in a dengue-endemic country toward testing for Zika infection among patients with dengue-like illnesses. Methods: A cross-sectional online survey was conducted among general practitioners (GPs) in Indonesia. The survey assessed their attitude and also collected sociodemographic data, characteristics of their medical education, professional background, and workplace, and exposure to Zika cases. A two-step logistic regression analysis was used to assess possible variables associated with these attitudes. Results: A total of 370 GPs were included in the final analysis of which 70.8% had good attitude. Unadjusted analyses suggested that GPs who were 30 years old or older and those who had medical experience five years or longer had lower odds of having a positive attitude compared to those who aged younger than 30 years and those who had medical experience less than five years, OR: 0.58; 95%CI: 0.37, 0.91 and OR: 0.55; 95%CI: 0.35, 0.86, respectively. No explanatory variable was associated with attitude in the fully adjusted model. Conclusion: Our findings point to younger GPs with a shorter medical experience being more likely to consider testing for Zika infection among their patients presenting with dengue-like illnesses. Strategic initiatives may be needed to enhance older or longer-experienced physicians' capacity in diagnosing Zika infection.

scholarly journals Infrastructural and Human Factors affecting Safety Outcomes of Cyclists

2018 ◽  
Author(s):  
Sergio Useche ◽  
Luis Montoro ◽  
Francisco Alonso ◽  
Oscar Oviedo-Trespalacios
Keyword(s):  
Human Factors ◽  
Online Survey ◽  
Demographic Data ◽  
Risky Behaviors ◽  
Cross Sectional Study ◽  
Severe Injuries ◽  
Related Factors ◽  
Cross Sectional ◽  
Road Crashes ◽  
Safety Outcomes

The increasing number of registered road crashes involving cyclists during the last decade, and the high proportion of road crashes resulting in severe injuries and fatalities among cyclists constitutes a global issue for community health, urban development, and sustainability. Nowadays, the incidence of many risk factors for road crashes of cyclists remains largely unexplained. Given the importance of this issue, the present study has been conducted with the aim of determining relationships between infrastructural, human factors and safety outcomes of cyclists. Objectives: This study aimed, first, to examine the relationship between key infrastructural and human factors present in cycling, bicycle-user characteristics, and their self-reported experience with road crashes. And second, to determine whether a set of key infrastructural and human factors may predict their self-reported road crashes. Methods: For this cross-sectional study, a total of 1064 cyclists (38.8% women, 61.2% men; M = 32.8 years of age) from 20 different countries across Europe, South America and North America, participated in an online survey composed of four sections: demographic data and cycling-related factors, human factors, perceptions on infrastructural factors, and road crashes suffered. Results: The results of this study showed significant associations between human factors, infrastructural conditions and self-reported road crashes. Also, a logistic regression model found that self-reported road crashes of cyclists could be predicted through variables such as age, riding intensity, risky behaviors, and problematic user/infrastructure interactions. Conclusions: The results of this study suggest that self-reported road crashes of cyclists are influenced by features related to the user and their interaction with infrastructural characteristics of the road.

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