scholarly journals A Novel Cognition-Guided Neurofeedback BCI Dataset on Nicotine Addiction

2021 ◽  
Vol 15 ◽  
Author(s):  
Junjie Bu ◽  
Chang Liu ◽  
Huixing Gou ◽  
Hefan Gan ◽  
Yan Cheng ◽  
...  

Compared with the traditional neurofeedback paradigm, the cognition-guided neurofeedback brain–computer interface (BCI) is a novel paradigm with significant effect on nicotine addiction. However, the cognition-guided neurofeedback BCI dataset is extremely lacking at present. This paper provides a BCI dataset based on a novel cognition-guided neurofeedback on nicotine addiction. Twenty-eight participants are recruited and involved in two visits of neurofeedback training. This cognition-guided neurofeedback includes two phases: an offline classifier construction and a real-time neurofeedback training. The original electroencephalogram (EEG) raw data of two phases are provided and evaluated in this paper. The event-related potential (ERP) amplitude and channel waveform suggest that our BCI dataset is of good quality and consistency. During neurofeedback training, the participants’ smoking cue reactivity patterns have a significant reduction. The mean accuracy of the multivariate pattern analysis (MVPA) classifier can reach approximately 70%. This novel cognition-guided neurofeedback BCI dataset can be used to develop comparisons with other neurofeedback systems and provide a reference for the development of other BCI algorithms and neurofeedback paradigms on addiction.

2019 ◽  
Author(s):  
Andrew A. Chen ◽  
Joanne C. Beer ◽  
Nicholas J. Tustison ◽  
Philip A. Cook ◽  
Russell T. Shinohara ◽  
...  

AbstractTo acquire larger samples for answering complex questions in neuroscience, researchers have increasingly turned to multi-site neuroimaging studies. However, these studies are hindered by differences in images acquired across multiple scanners. These effects have been shown to bias comparison between scanners, mask biologically meaningful associations, and even introduce spurious associations. To address this, the field has focused on harmonizing data by removing scanner-related effects in the mean and variance of measurements. Contemporaneously with the increase in popularity of multi-center imaging, the use of multivariate pattern analysis (MVPA) has also become commonplace. These approaches have been shown to provide improved sensitivity, specificity, and power due to their modeling the joint relationship across measurements in the brain. In this work, we demonstrate that methods for removing scanner effects in mean and variance may not be sufficient for MVPA. This stems from the fact that such methods fail to address how correlations between measurements can vary across scanners. Data from the Alzheimer’s Disease Neuroimaging Initiative is used to show that considerable differences in covariance exist across scanners and that popular harmonization techniques do not address this issue. We also propose a novel methodology that harmonizes covariance of multivariate image measurements across scanners and demonstrate its improved performance in data harmonization.


2017 ◽  
Author(s):  
Stefan Bode ◽  
Daniel Feuerriegel ◽  
Daniel Bennett ◽  
Phillip M. Alday

AbstractIn recent years, neuroimaging research in cognitive neuroscience has increasingly used multivariate pattern analysis (MVPA) to investigate higher cognitive functions. Here we present DDTBOX, an open-source MVPA toolbox for electroencephalography (EEG) data. DDTBOX runs under MATLAB and is well integrated with the EEGLAB/ERPLAB and Fieldtrip toolboxes (Delorme and Makeig, 2004; Lopez-Calderon and Luck, 2014; Oostenveld et al. 2011). It trains support vector machines (SVMs) on patterns of event-related potential (ERP) amplitude data, following or preceding an event of interest, for classification or regression of experimental variables. These amplitude patterns can be extracted across space/electrodes (spatial decoding), time (temporal decoding), or both (spatiotemporal decoding). DDTBOX can also extract SVM feature weights, generate empirical chance distributions based on shuffled-labels decoding for group-level statistical testing, provide estimates of the prevalence of decodable information in the population, and perform a variety of corrections for multiple comparisons. It also includes plotting functions for single subject and group results. DDTBOX complements conventional analyses of ERP components, as subtle multivariate patterns can be detected that would be overlooked in standard analyses. It further allows for a more explorative search for information when no ERP component is known to be specifically linked to a cognitive process of interest. In summary, DDTBOX is an easy-to-use and open-source toolbox that allows for characterising the time-course of information related to various perceptual and cognitive processes. It can be applied to data from a large number of experimental paradigms and could therefore be a valuable tool for the neuroimaging community.


Children ◽  
2021 ◽  
Vol 8 (3) ◽  
pp. 186
Author(s):  
Valeria Calcaterra ◽  
Giacomo Biganzoli ◽  
Gloria Pelizzo ◽  
Hellas Cena ◽  
Alessandra Rizzuto ◽  
...  

Background: The prevalence of pediatric metabolic syndrome is usually closely linked to overweight and obesity; however, this condition has also been described in children with disabilities. We performed a multivariate pattern analysis of metabolic profiles in neurologically impaired children and adolescents in order to reveal patterns and crucial biomarkers among highly interrelated variables. Patients and methods: We retrospectively reviewed 44 cases of patients (25M/19F, mean age 12.9 ± 8.0) with severe disabilities. Clinical and anthropometric parameters, body composition, blood pressure, and metabolic and endocrinological assessment (fasting blood glucose, insulin, total cholesterol, high-density lipoprotein cholesterol, triglycerides, glutamic oxaloacetic transaminase, glutamate pyruvate transaminase, gamma-glutamyl transpeptidase) were recorded in all patients. As a control group, we evaluated 120 healthy children and adolescents (61M/59F, mean age 12.9 ± 2.7). Results: In the univariate analysis, the children-with-disabilities group showed a more dispersed distribution, thus with higher variability of the features related to glucose metabolism and insulin resistance (IR) compared to the healthy controls. The principal component (PC1), which emerged from the PC analysis conducted on the merged dataset and characterized by these variables, was crucial in describing the differences between the children-with-disabilities group and controls. Conclusion: Children and adolescents with disabilities displayed a different metabolic profile compared to controls. Metabolic syndrome (MetS), particularly glucose metabolism and IR, is a crucial point to consider in the treatment and care of this fragile pediatric population. Early detection of the interrelated variables and intervention on these modifiable risk factors for metabolic disturbances play a central role in pediatric health and life expectancy in patients with a severe disability.


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