scholarly journals Acrylamide Contents of Local Snacks in Singapore

2021 ◽  
Vol 8 ◽  
Author(s):  
Michelle Ting Yun Yeo ◽  
Xinyan Bi ◽  
Christiani Jeyakumar Henry
Keyword(s):  
Mass Spectrometry ◽  
Ethnic Groups ◽  
Raw Materials ◽  
Age Groups ◽  
Tandem Mass ◽  
Average Content ◽  
Chromatography Tandem Mass Spectrometry ◽  
Liquid Chromatography Tandem Mass ◽  
Different Levels ◽  
Insight Into

Acrylamide is a carcinogen that forms in foods processed at high temperatures. In this study, acrylamide contents of 30 local snacks commonly consumed by the three ethnic groups (Malay, Chinese, and Indian) in Singapore were analysed by using liquid chromatography-tandem mass spectrometry (LC-MS/MS). These snacks were chosen because they were consumed regularly by people of different classes and age groups in Singapore. Our results showed that the average content of acrylamide in Indian snacks (102.23 ng/g) was higher than those in Malay (75.14 ng/g) and Chinese snacks (70.78 ng/g). The high acrylamide levels in several snacks was probably due to the processing methods and the usage of acrylamide-inducing raw materials. Same snacks prepared by different manufacturers contained different levels of acrylamide, suggesting the possibility of acrylamide reduction in these snacks. This study provides an insight into the acrylamide levels of snacks commonly consumed by the three different ethnic groups in Singapore.

scholarly journals Ultrasound Assisted Method Development for the Determination of Selected Sulfonamides in Honey Using Liquid Chromatography-Tandem Mass Spectrometry

2016 ◽  
Vol 16 (2) ◽  
pp. 289-295
Author(s):  
M. Manimekalai ◽  
Anand Sheshadri ◽  
K. Suresh Kumar ◽  
Ashish Rawson
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Tandem Mass Spectrometry ◽  
Method Development ◽  
Age Groups ◽  
Veterinary Drug ◽  
Tandem Mass ◽  
Chromatography Tandem Mass Spectrometry ◽  
Liquid Chromatography Tandem Mass

Honey is a highly valuable natural product, which is consumed by people of all age groups unaware of the high load of veterinary drug residues present. Sulfonamides are one such class of veterinary drugs, which are used in apiculture in higher amounts and impose a lot of negative health effects. This paper describes an analytical method developed for simultaneous determination of two Sulfonamides (Sulfamethizole and Trimethoprim) in honey using liquid chromatography- tandem mass spectrometry (LC-MS/MS). Suitable fragmentor voltage and collision energy were optimised for both the analytes. Five different sample preparation techniques based on ultrasonication were evaluated. In which ultrasonication at 80% amplitude, 5 minutes at 45°C gave improved recoveries. On validation, the developed method showed good linearity with r2 values in the range of 0.98-0.99 for both the sulfonamides. The effect of matrix on the method developed was evaluated and was found that the sample matrix does not pose considerable interferences with excellent linearities with r2 values above 0.95 for both the analytes. The method developed was found to be very selective and can find application in routine analysis for the determination of sulfonamides from honey samples.

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