scholarly journals Optimization of Bone Health in Children before and after Renal Transplantation: Current Perspectives and Future Directions

2014 ◽  
Vol 2 ◽  
Author(s):  
Kristen Sgambat ◽  
Asha Moudgil
Keyword(s):  
Renal Transplantation ◽  
Bone Health ◽  
Future Directions ◽  
Before And After

scholarly journals Twelve Years of the Italian Program to Enhance Relational and Communication Skills (PERCS)

2021 ◽  
Vol 18 (2) ◽  
pp. 439
Author(s):  
Lidia Borghi ◽  
Elaine C. Meyer ◽  
Elena Vegni ◽  
Roberta Oteri ◽  
Paolo Almagioni ◽  
...  
Keyword(s):  
Communication Skills ◽  
Repeated Measures ◽  
Behavioral Changes ◽  
Chi Square ◽  
Future Directions ◽  
Public And Private ◽  
Learner Centered ◽  
Difficult Conversations ◽  
Booster Sessions ◽  
Before And After

To describe the experience of the Italian Program to Enhance Relations and Communication Skills (PERCS-Italy) for difficult healthcare conversations. PERCS-Italy has been offered in two different hospitals in Milan since 2008. Each workshop lasts 5 h, enrolls 10–15 interdisciplinary participants, and is organized around simulations and debriefing of two difficult conversations. Before and after the workshops, participants rate their preparation, communication, relational skills, confidence, and anxiety on 5-point Likert scales. Usefulness, quality, and recommendation of the program are also assessed. Descriptive statistics, t-tests, repeated-measures ANOVA, and Chi-square were performed. A total of 72 workshops have been offered, involving 830 interdisciplinary participants. Participants reported improvements in all the dimensions (p < 0.001) without differences across the two hospitals. Nurses and other professionals reported a greater improvement in preparation, communication skills, and confidence, compared to physicians and psychosocial professionals. Usefulness, quality, and recommendation of PERCS programs were highly rated, without differences by discipline. PERCS-Italy proved to be adaptable to different hospital settings, public and private. After the workshops, clinicians reported improvements in self-reported competencies when facing difficult conversations. PERCS-Italy’s sustainability is based on the flexible format combined with a solid learner-centered approach. Future directions include implementation of booster sessions to maintain learning and the assessment of behavioral changes.

LV remodelling after renal transplantation: future directions

Heart ◽  
2015 ◽  
Vol 101 (22) ◽  
pp. 1776-1777
Author(s):  
Ming-Jui Hung
Keyword(s):  
Renal Transplantation ◽  
Future Directions

A Critical Assessment and Review of Artificial Intelligence in Facial Paralysis Analysis: Uncovering the Truth

FACE ◽  
2021 ◽  
pp. 273250162110228
Author(s):  
David T. Mitchell ◽  
David Z. Allen ◽  
Matthew R. Greives ◽  
Phuong D. Nguyen
Keyword(s):  
Artificial Intelligence ◽  
Facial Paralysis ◽  
Critical Assessment ◽  
Facial Emotion ◽  
Data Systems ◽  
Computer Algorithms ◽  
Future Directions ◽  
Sample Data ◽  
Before And After ◽  
Facial Reanimation

Machine learning is a rapidly growing subset of artificial intelligence (AI) which involves computer algorithms that automatically build mathematical models based on sample data. Systems can be taught to learn from patterns in existing data in order to make similar conclusions from new data. The use of AI in facial emotion recognition (FER) has become an area of increasing interest for providers who wish to quantify facial emotion before and after interventions such as facial reanimation surgery. While FER deep learning algorithms are less subjective when compared to layperson assessments, the databases used to train them can greatly alter their outputs. There are currently many well-established modalities for assessing facial paralysis, but there is also increasing interest in a more objective and universal measurement system to allow for consistent assessments between practitioners. The purpose of this article is to review the development of AI, examine its existing uses in facial paralysis assessment, and discuss the future directions of its implications.

Study assessing the efficacy of herbal teas on bone health and quality of life in a population with osteopenia: rooibos actions on melatonin and tulsi actions on quality of life.

2021 ◽  
Vol 4 (2) ◽  
pp. 270-298
Author(s):  
Fahima Munmun ◽  
Alyssa Linden ◽  
Hunter Hanlon ◽  
Hannah Enderby ◽  
Paula Witt-Enderby
Keyword(s):  
Quality Of Life ◽  
Oxidative Stress ◽  
Bone Health ◽  
Human Mesenchymal Stem Cell ◽  
Melatonin Receptors ◽  
Cooperative Effort ◽  
Translational Study ◽  
Before And After

The purpose of the OsTea translational study was to assess the efficacy of teas (tulsi, rooibos, oolong) compared to placebo (coriander) on markers of bone health and quality of life (QOL) in those with osteopenia and on human mesenchymal stem cell (hMSC) differentiation into osteoblasts to identify potential mechanisms of action. Following consumption of tea (3 times/day; 90 days), participants collected a urine sample during the night (10pm-6am) and filled in questionnaires before and after the study. Rooibos consumption demonstrated a significant decrease in urinary CTX levels vs placebo; trended towards increases in nocturnal melatonin levels (p=0.06); significantly decreased serotonin-producing microbes in the gut; and demonstrated trends towards improvements (p=0.09) in QUALIOST emotional parameters. Tulsi consumption primarily affected subjective measures, such as significantly improved scores for PSS, STAI-trait anxiety, and osteoporosis/osteopenia-related parameters in the QUALIOST. To further identify potential mechanisms underlying these actions of rooibos on CTX and melatonin (urinary and gut), rooibos and melatonin effects on human osteoblastogenesis were carried out for 21 days under oxidative stress conditions to mimic osteopenia.  Although both rooibos and melatonin protected against oxidative stress-induced loss of osteoblasts in vitro, their underlying mechanisms were different.  Melatonin, like tulsi and oolong, demonstrated the greatest protection against oxidative stress at days 10-11 of exposure, which was due to effects on hMSC viability and through melatonin receptors. Rooibos, on the other hand, demonstrated protection at days 10-11 and 20-21, which was through signaling mechanisms involved in differentiation processes and not on cell viability. These findings suggest that the clinical actions of rooibos on decreasing CTX levels in a population with osteopenia may be through a cooperative effort between melatonin and rooibos by protecting hMSC viability against oxidative stress-induced loss and by promoting osteoblast differentiation, respectively.  This study also supports the use of tulsi for improving quality of life in a population susceptible to osteoporosis.

scholarly journals P0299EVALUATION OF THE CORRELATION BETWEEN VITAMIN D LEVELS AND THROMBOCYTE MARKERS IN PATIENTS WITH DİALYSİS, CHRONIC RENAL DISEASE AND RENAL TRANSPLANTATION PATIENTS

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
KÖNÜL AHMEDOVA ◽  
Garip SAHIN ◽  
Cengiz Bal ◽  
Rüya Mutluay
Keyword(s):  
Vitamin D ◽  
Renal Transplantation ◽  
Renal Disease ◽  
Negative Correlation ◽  
Chronic Renal Disease ◽  
Significant Negative Correlation ◽  
Vitamin D Supplementation ◽  
Control Group ◽  
Before And After ◽  
Grade 3

Abstract Background and Aims 25(OH)D3 levels are known to be lower in patients with chronic renal disease (CRD). Vitamin D supplementation has been shown to have beneficial effects on mortality in these patients. In our study, we have evaluated the pleiotropic effect of vitamin D on thrombocyte markers, which is known very little by most. Method The main thrombocyte function markers (MPV, PDW and PCT) were obtained in patients which underwent dialysis, renal transplantation and patients with grade 3-4 CRD before and after vitamin D supplementation. 40 healthy individuals were chosen as control group and 24 patients underwent renal transplantation, 25 patients underwent dialysis for at least 3 months, 32 patients were diagnosed as Grade 3-4 CRD. All of the patients above had 25(OH)D3 levels &lt;20ng/mL (&lt;50nmol/L). Thrombocyte markers were evaluated before and after vitamin D supplementation (which was given 50.000 IU orally once a week for 8 weeks). Results Statistically no significant difference were found between MPV values in- and across- group comparison before and after vitamin D supplementation. After the correlation analyses were reviewed, statistically significant negative correlation was found (r=-0,422 p&lt;0.05) between ΔMPV and ΔVitamin D in renal transplantation group. Also statistically significant positive correlation was found between ΔPDW and ΔVitamin D. In the control group with healty participants, a statistically significant negative correlation was found (r=-0,493 p&lt;0.05) between ΔVitamin D and ΔThrombocyte count. In the dialysis group a statistically significant negative correlation was found (r=-0,422 p&lt;0.05) between ΔVitamin D and ΔMPV. Conclusion A significant correlation was found particularly between Vitamin D and MPV in dialysis and renal transplantation patients. In order to prevent cardiovascular events due to thrombosis caused by Vitamin D deficiency which increases MPV, it has been thought that Vitamin D supplementation and antiaggregant therapy might be beneficial.

EVALUATION OF PATIENTʼS SEXUAL FUNCTION BEFORE AND AFTER RENAL TRANSPLANTATION

2010 ◽  
Vol 90 ◽  
pp. 932
Author(s):  
Darabi M.R. Mahboub ◽  
R. Taghavi ◽  
M. H. Shakibi
Keyword(s):  
Renal Transplantation ◽  
Sexual Function ◽  
Before And After

scholarly journals Impact of Changing Trend in Cold Ischaemic Time on Operating Times in Renal Transplantation

2006 ◽  
Vol 88 (7) ◽  
pp. 667-671 ◽  
Author(s):  
Ying-Ying Seow ◽  
Hany Riad ◽  
Philip Dyer
Keyword(s):  
Renal Transplantation ◽  
Working Hours ◽  
Out Of Hours ◽  
Time Of Surgery ◽  
European Working ◽  
Before And After ◽  
Changing Trend ◽  
Cadaver Kidney ◽  
Time Periods ◽  
Working Time Directive

INTRODUCTION The European Working Time Directive (EWTD) is calling for reduction in the working hours of doctors. Renal transplantation is well-recognised as an out-of-hours specialty. Our study looks at whether our renal transplant centre's attempt to reduce cold ischaemic time (CIT) has impacted on the pattern of operating times since this may have implications on the surgeons' working hours. PATIENTS AND METHODS We studied 883 adult cadaver kidney transplants performed between 1 January 1992 and 31 December 2002. CIT and time of surgery was obtained from a local audit database (< www.nwkta.org >) and that held by UK Transplant. Time of surgery was divided into 07:30–17:59 (day),18:00–23:59 (evening) and 00:00–07:29 (night). RESULTS CIT has decreased since 1992, with a significant reduction after 1998 (P = 0.0001). There was, however, no difference in the percentage of operations performed during the three time periods before and after 1998. Between 1999–2002, 51.4% of transplants took place out of hours (i.e. 18:00–07:29). CONCLUSIONS Reduction in CIT does not appear to have impacted on our operating times. The large amount of out-of-hours work is, however, not compliant with EWTD requirements.

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