scholarly journals Depression Is Associated With the Absence of Sex Differences in the 2D:4D Ratio of the Right Hand

2019 ◽  
Vol 10 ◽  
Author(s):  
Simon Sanwald ◽  
Katharina Widenhorn-Müller ◽  
Jennifer Wernicke ◽  
Cornelia Sindermann ◽  
Markus Kiefer ◽  
...  
Keyword(s):  
Sex Differences ◽  
Right Hand ◽  
The Right

scholarly journals Is 2D:4D the most sexually differentiated among finger-length ratios? Answers from a meta-analysis

2021 ◽  
Author(s):  
Martin Voracek
Keyword(s):  
Sex Differences ◽  
Meta Analysis ◽  
Digit Ratio ◽  
Human Hand ◽  
Finger Length ◽  
Right Hand ◽  
The Usa ◽  
Scanned Images ◽  
The Uk ◽  
The Right

The second-to-fourth digit ratio (2D:4D) is a sexually differentiated trait of human hand anatomy which presently is frequently used in anthropological, biomedical, and psychological studies as a putative (retrospective and indirect) marker for prenatal androgen levels. Apart from the traditionally studied 2D:4D ratio, five further finger-length ratios can be constructed for the human hand (2D:3D, 2D:5D, 3D:4D, 3D:5D, 4D:5D). These have been probed by only a minority of digit ratio studies. It is not firmly established whether all of these finger-length ratios actually exhibit sex differences and whether 2D:4D indeed is the most sexually differentiated among them. To clarify these questions, a meta-analysis on studies reporting data from mixed-sex samples on all six finger-length ratios of the right and left hands in healthy normals was conducted. This study inclusion criterion was satisfied by 18 independent samples (including two unpublished), representing 4198 individuals (1989 men and 2209 women), seven countries (Australia, Austria, China, Greece, Jamaica, the UK, and the USA), different age bands (child, young adult, and adult samples), and different finger-length measurement methods (from printouts of flatbed-scanned images or photocopies of the hands or direct measurements). The meta-analytical results showed that men invariably had lower finger-length ratios than women. Although these sex differences were significant for all six finger-length ratios, effects were not strong, but rather ranged from small (d=-0.21, for right-hand 4D:5D) to medium (d= 0.44, for right-hand 2D:4D). 2D:5D was equally sexually differentiated as 2D:4D. Sex differences for finger-length ratios calculated from nonadjacent fingers (2D:4D, 2D:5D, 3D:5D) generally were somewhat more pronounced than for those calculated from adjacent fingers (2D:3D, 3D:4D, 4D:5D). Discussed are practical consequences of these findings for digit ratio research.

Editorial Note

1946 ◽  
Vol 11 (1) ◽  
pp. 2-2
Keyword(s):  
Editorial Note ◽  
Speech Sounds ◽  
Left Hand ◽  
Hand Column ◽  
Right Hand ◽  
Infant Speech ◽  
The Right

In the article “Infant Speech Sounds and Intelligence” by Orvis C. Irwin and Han Piao Chen, in the December 1945 issue of the Journal, the paragraph which begins at the bottom of the left hand column on page 295 should have been placed immediately below the first paragraph at the top of the right hand column on page 296. To the authors we express our sincere apologies.

Eosinophilic vasculitis: an inhabitual and resistant manifestation of a vasculitis

VASA ◽  
2010 ◽  
Vol 39 (4) ◽  
pp. 344-348 ◽  
Author(s):  
Jandus ◽  
Bianda ◽  
Alerci ◽  
Gallino ◽  
Marone
Keyword(s):  
Skin Biopsy ◽  
Intravenous Iron ◽  
Small Vessel Vasculitis ◽  
High Dose ◽  
Raynaud Phenomenon ◽  
The Third ◽  
Left Elbow ◽  
Right Hand ◽  
The Right ◽  
Trunk Skin

A 55-year-old woman was referred because of diffuse pruritic erythematous lesions and an ischemic process of the third finger of her right hand. She was known to have anaemia secondary to hypermenorrhea. She presented six months before admission with a cutaneous infiltration on the left cubital cavity after a paravenous leakage of intravenous iron substitution. She then reported a progressive pruritic erythematous swelling of her left arm and lower extremities and trunk. Skin biopsy of a lesion on the right leg revealed a fibrillar, small-vessel vasculitis containing many eosinophils.Two months later she reported Raynaud symptoms in both hands, with a persistent violaceous coloration of the skin and cold sensation of her third digit of the right hand. A round 1.5 cm well-delimited swelling on the medial site of the left elbow was noted. The third digit of her right hand was cold and of violet colour. Eosinophilia (19 % of total leucocytes) was present. Doppler-duplex arterial examination of the upper extremities showed an occlusion of the cubital artery down to the palmar arcade on the right arm. Selective angiography of the right subclavian and brachial arteries showed diffuse alteration of the blood flow in the cubital artery and hand, with fine collateral circulation in the carpal region. Neither secondary causes of hypereosinophilia nor a myeloproliferative process was found. Considering the skin biopsy results and having excluded other causes of eosinophilia, we assumed the diagnosis of an eosinophilic vasculitis. Treatment with tacrolimus and high dose steroids was started, the latter tapered within 12 months and then stopped, but a dramatic flare-up of the vasculitis with Raynaud phenomenon occurred. A new immunosupressive approach with steroids and methotrexate was then introduced. This case of aggressive eosinophilic vasculitis is difficult to classify into the usual forms of vasculitis and constitutes a therapeutic challenge given the resistance to current immunosuppressive regimens.

Detection of Sarcoidosis Based on Subcutaneous Nodules in the Dorsum of the Right Hand

2014 ◽  
Vol 76 (1) ◽  
pp. 14-17
Author(s):  
Yoshiyuki KUWAE ◽  
Kunitaka HARUNA ◽  
Yasushi SUGA
Keyword(s):  
Subcutaneous Nodules ◽  
Right Hand ◽  
The Right

Construct Validity

2017 ◽  
Author(s):  
Richard McCleary ◽  
David McDowall ◽  
Bradley J. Bartos
Keyword(s):  
Time Series ◽  
Construct Validity ◽  
Hypothesis Test ◽  
Secondary Data ◽  
Time Frame ◽  
Primary Data ◽  
Optimal Time ◽  
Intervention Model ◽  
Right Hand ◽  
The Right

Chapter 8 focuses on threats to construct validity arising from the left-hand side time series and the right-hand side intervention model. Construct validity is limited to questions of whether an observed effect can be generalized to alternative cause and effect measures. The “talking out” self-injurious behavior time series, shown in Chapter 5, are examples of primary data. Researchers often have no choice but to use secondary data that were collected by third parties for purposes unrelated to any hypothesis test. Even in those less-than-ideal instances, however, an optimal time series can be constructed by limiting the time frame and otherwise paying attention to regime changes. Threats to construct validity that arise from the right-hand side intervention model, such as fuzzy or unclear onset and responses, are controlled by paying close attention to the underlying theory. Even a minimal theory should specify the onset and duration of an impact.

scholarly journals Digit Variability in Carotenoid Scores Obtained with the Veggie Meter: A Pilot Study (P02-001-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Velarie Ansu ◽  
Stephanie Dickinson ◽  
Alyce Fly
Keyword(s):  
Indiana University ◽  
Left Hand ◽  
Funding Sources ◽  
Right Hand ◽  
Period Data ◽  
The Mean ◽  
The Right ◽  
Post Hoc ◽  
Main Effects ◽  
Mean Square Errors

Abstract Objectives To determine which digit and hand have the highest and lowest skin carotenoid scores, to compare inter-and-intra-hand variability of digits, and to determine if results are consistent with another subject. Methods Two subjects’ first(F1), second(F2), third(F3) and fifth(F5) digits on both hands were measured for skin carotenoids with a Veggie Meter, for 3 times on each of 18 days over a 37-day period. Data were subjected to ANOVA in a factorial treatment design to determine main effects for hand (2 levels), digits (4), and days (18) along with interactions. Differences between digits were determined by Tukey's post hoc test. Results There were significant hand x digit, hand x day, digit x day, and hand x digit x day interactions and significant simple main effects for hand, digit, and day (all P < 0.001). Mean square errors were 143.67 and 195.62 for subject A and B, respectively, which were smaller than mean squares for all main effects and interactions. The mean scores ± SD for F1, F2, F3, and F5 digits for the right vs left hands for subject A were F1:357.13 ± 45.97 vs 363.74 ± 46.94, F2:403.17 ± 44.77 vs. 353.20 ± 44.13, F3:406.76 ± 43.10 vs. 357.11 ± 45.13, and F5:374.95 ± 53.00 vs. 377.90 ± 47.38. For subject B, the mean scores ± SD for digits for the right vs left hands were F1:294.72 ± 61.63 vs 280.71 ± 52.48, F2:285.85 ± 66.92 vs 252.67 ± 67.56, F3:268.56 ± 57.03 vs 283.22 ± 45.87, and F5:288.18 ± 34.46 vs 307.54 ± 40.04. The digits on the right hand of both subjects had higher carotenoid scores than those on the left hands, even though subjects had different dominant hands. Subject A had higher skin carotenoid scores on the F3 and F2 digits for the right hand and F5 on the left hand. Subject B had higher skin carotenoid scores on F5 (right) and F1 (left) digits. Conclusions The variability due to hand, digit, and day were all greater than that of the 3 replicates within the digit-day for both volunteers. This indicates that data were not completely random across the readings when remeasuring the same finger. Different fingers displayed higher carotenoid scores for each volunteer. There is a need to conduct a larger study with more subjects and a range of skin tones to determine whether the reliability of measurements among digits of both hands is similar across the population. Funding Sources Indiana University.

scholarly journals Association between Hippocampal Volume and Working Memory in 10,000+ 9–10-Year-Old Children: Sex Differences

Children ◽  
2021 ◽  
Vol 8 (5) ◽  
pp. 411
Author(s):  
Shervin Assari ◽  
Shanika Boyce ◽  
Tanja Jovanovic
Keyword(s):  
Working Memory ◽  
Sex Differences ◽  
Parental Education ◽  
Predictor Variable ◽  
National Sample ◽  
Hippocampal Volume ◽  
Study Data ◽  
Cross Sectional ◽  
The Right

Aim: This study tested sex differences in the association between hippocampal volume and working memory of a national sample of 9–10-year-old children in the US. As the hippocampus is functionally lateralized (especially in task-related activities), we explored the results for the right and the left hippocampus. Methods: This is a cross-sectional study using the Adolescent Brain Cognitive Development (ABCD) Study data. This analysis included baseline ABCD data (n = 10,093) of children between ages 9 and 10 years. The predictor variable was right and left hippocampal volume measured by structural magnetic resonance imaging (sMRI). The primary outcome, list sorting working memory, was measured using the NIH toolbox measure. Sex was the moderator. Age, race, ethnicity, household income, parental education, and family structure were the covariates. Results: In the overall sample, larger right (b = 0.0013; p < 0.001) and left (b = 0.0013; p < 0.001) hippocampal volumes were associated with higher children’s working memory. Sex had statistically significant interactions with the right (b = −0.0018; p = 0.001) and left (b = −0.0012; p = 0.022) hippocampal volumes on children’s working memory. These interactions indicated stronger positive associations between right and left hippocampal volume and working memory for females compared to males. Conclusion: While right and left hippocampal volumes are determinants of children’s list sorting working memory, these effects seem to be more salient for female than male children. Research is needed on the role of socialization, sex hormones, and brain functional connectivity as potential mechanisms that may explain the observed sex differences in the role of hippocampal volume as a correlate of working memory.

scholarly journals Approximating pointwise products of quasimodes

2020 ◽  
Vol 32 (3) ◽  
pp. 541-552
Author(s):  
Mei Ling Jin
Keyword(s):  
Vector Space ◽  
Harmonic Analysis ◽  
Riemannian Manifolds ◽  
Spectral Projection ◽  
Beltrami Operator ◽  
Singular Potentials ◽  
Link Type ◽  
Right Hand ◽  
Low Degree ◽  
The Right

AbstractWe obtain approximation bounds for products of quasimodes for the Laplace–Beltrami operator on compact Riemannian manifolds of all dimensions without boundary. We approximate the products of quasimodes uv by a low-degree vector space {B_{n}}, and we prove that the size of the space {\dim(B_{n})} is small. In this paper, we first study bilinear quasimode estimates of all dimensions {d=2,3}, {d=4,5} and {d\geq 6}, respectively, to make the highest frequency disappear from the right-hand side. Furthermore, the result of the case {\lambda=\mu} of bilinear quasimode estimates improves {L^{4}} quasimodes estimates of Sogge and Zelditch in [C. D. Sogge and S. Zelditch, A note on L^{p}-norms of quasi-modes, Some Topics in Harmonic Analysis and Applications, Adv. Lect. Math. (ALM) 34, International Press, Somerville 2016, 385–397] when {d\geq 8}. And on this basis, we give approximation bounds in {H^{-1}}-norm. We also prove approximation bounds for the products of quasimodes in {L^{2}}-norm using the results of {L^{p}}-estimates for quasimodes in [M. Blair, Y. Sire and C. D. Sogge, Quasimode, eigenfunction and spectral projection bounds for Schrodinger operators on manifolds with critically singular potentials, preprint 2019, https://arxiv.org/abs/1904.09665]. We extend the results of Lu and Steinerberger in [J. F. Lu and S. Steinerberger, On pointwise products of elliptic eigenfunctions, preprint 2018, https://arxiv.org/abs/1810.01024v2] to quasimodes.

scholarly journals Differences in digit ratios between gay men who prefer receptive versus insertive sex roles indicate a role for prenatal androgen

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Ashlyn Swift-Gallant ◽  
Victor Di Rita ◽  
Christina A. Major ◽  
Christopher J. Breedlove ◽  
Cynthia L. Jordan ◽  
...  
Keyword(s):  
Gay Men ◽  
Sex Role ◽  
Gender Nonconformity ◽  
Critical Periods ◽  
Same Sex ◽  
Digit Ratios ◽  
Right Hand ◽  
Prenatal Androgens ◽  
The Right ◽  
Prenatal Androgen

AbstractAmong non-human mammals, exposure to androgens during critical periods of development leads to gynephilia (attraction to females), whereas the absence or low levels of prenatal androgens leads to androphilia (attraction to males). However, in humans, retrospective markers of prenatal androgens have only been associated with gynephilia among women, but not with androphilia among men. Here, we asked whether an indirect indication of prenatal androgen exposure, 2D:4D, differs between subsets of gay men delineated by anal sex role (ASR). ASR was used as a proxy for subgroups because ASR groups tend to differ in other measures affected by brain sexual differentiation, such as gender conformity. First, we replicated the finding that gay men with a receptive ASR preference (bottoms) report greater gender nonconformity (GNC) compared to gay men with an insertive ASR preference (tops). We then found that Tops have a lower (male-typical) average right-hand digit ratio than Bottoms, and that among all gay men the right-hand 2D:4D correlated with GNC, indicating that a higher (female-typical) 2D:4D is associated with increased GNC. Differences were found between non-exclusive and exclusive same-sex attraction and GNC, and ASR group differences on digit ratios do not reach significance when all non-heterosexual men are included in the analyses, suggesting greater heterogeneity in the development of non-exclusive same-sex sexual orientations. Overall, results support a role for prenatal androgens, as approximated by digit ratios, in influencing the sexual orientation and GNC of a subset of gay men.

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