scholarly journals Facility-Based Maternal Death in Western Africa: A Systematic Review

2018 ◽  
Vol 6 ◽  
Author(s):  
Nathali Gunawardena ◽  
Ghose Bishwajit ◽  
Sanni Yaya
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Ratnasari D. Cahyanti ◽  
Widyawati Widyawati ◽  
Mohammad Hakimi

Abstract Background Maternal Death Reviews (MDR) can assist in formulating prevention strategies to reduce maternal mortality. To support MDR, an adequate MDR instrument is required to accurately identify the underlying causes of maternal deaths. We conducted a systematic review and meta-analysis to determine the reliability of maternal death instruments for conducting the MDR process. Method Three databases: PubMed, ProQuest and EBSCO were systematically searched to identify related research articles published between January 2004 and July 2019. The review and meta-analysis involved identification of measurement tools to conduct MDR in all or part of maternal audit. Eligibiliy and quality of studies were evaluated using the Modified Quality Appraisal of Diagnostic Reliability (QAREL) Checklist: Reliability Studies. Results Overall, 242 articles were identified. Six articles examining the instrument used for MDR in 4 countries (4 articles on verbal autopsy (VA) and 2 articles on facility-based MDR) were included. None of studies identified reliability in evaluation instruments assessing maternal audit cycle as a comprehensive approach. The pooled kappa for the MDR instruments was 0.72 (95%CI:0.43–0.99; p < 0.001) with considerable heterogeneity (I2 = 96.19%; p < 0.001). Subgroup analysis of MDR instruments showed pooled kappa in VA of 0.89 (95%CI:0.52–1.25) and facility-based MDR of 0.48 (95%CI:0.15–0.82). Meta-regression analysis tended to show the high heterogeneity was likely associated with sample sizes, regions, and year of publications. Conclusions The MDR instruments appear feasible. Variation of the instruments suggest the need for judicious selection of MDR instruments by considering the study population and assessment during the target periods.


2021 ◽  
Author(s):  
Eugene Vernyuy Yeika ◽  
Brecht Ingelbeen ◽  
Ben-Lawrence Kemah ◽  
Frankline Sevidzem Wirsiy ◽  
Joseph Nkeangu Fomengia ◽  
...  

AbstractBackgroundSelf-medication with antibiotics (SMA) is a common practise in many parts of Africa, but its magnitude and drivers are not well-known. This systematic review evaluated and compared the prevalence, reasons, sources, and factors associated with of SMA within African sub-regions.MethodsAn electronic search of PubMed and Google Scholar databases was performed for observational studies conducted between January 2005 and February 2020. Two reviewers independently screened the abstracts and full texts using the PRISMA flowchart and equally performed quality assessment. Both quantitative and qualitative syntheses of selected studies were carried out.ResultsA total of 40 studies from 19 countries were selected for qualitative synthesis. The prevalence of SMA in Africa ranged from 12.1% to 93.9% with a median prevalence of 55.7% (IQR 41%-75%). Western Africa was the sub-region with the highest prevalence 70.1% (IQR 48.3%-82.1%), followed by Northern Africa with 48.1% (IQR 41.1-64.3%). We identified 27 different antibiotics used for self-medication from 13 different antibiotic classes. Penicillins were the most frequently used antibiotics followed by Tetracyclines and Fluoroquinolones. The most frequent indications for SMA were upper respiratory tract symptoms/infections (27 studies). Common sources of antibiotics used for self-medication were community pharmacies (31 studies), family/friends (20 studies), leftover antibiotics from previous treatments (19 studies), and patent medicine stores (18 studies). Commonly reported factors associated with SMA were no education/ low educational status (9 studies), male gender (5 studies), and low income / unemployment (2 studies).ConclusionsThe prevalence of SMA in Africa is high and varies across sub-regions with Western Africa having the highest prevalence. Drivers of SMA are complex comprising of socio-economic factors, limited access to healthcare coupled with absence or poorly implemented policies regulating antibiotic sales.


The Lancet ◽  
2006 ◽  
Vol 367 (9516) ◽  
pp. 1066-1074 ◽  
Author(s):  
Khalid S Khan ◽  
Daniel Wojdyla ◽  
Lale Say ◽  
A Metin Gülmezoglu ◽  
Paul FA Van Look

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Asteray Assmie Ayenew

Abstract Background Obstructed labor is a preventable obstetric complication. However, it is an important cause of maternal mortality and morbidity and of adverse outcomes for newborns in resource-limited countries in which undernutrition is common resulting in a small pelvis in which there is no easy access to functioning health facilities with a capacity to carry out operative deliveries. Therefore, this systematic review and meta-analysis aimed to estimate the incidence, causes, and maternofetal outcomes of obstructed labor among mothers who gave birth in Ethiopia. Method for this review, we used the standard PRISMA checklist guideline. Different online databases were used for the review: PubMed, Google Scholar, EMBASE, Cochrane Library, HINARI, AFRO Library Databases, and African Online Journals. Based on the adapted PICO principles, different search terms were applied to achieve and access the essential articles. The search included all published and unpublished observational studies written only in the English language and conducted in Ethiopia. Microsoft Excel 16 was used for data entrance, and Stata version 11.0 (Stata Corporation, College Station, Texas, USA) was used for data analysis. Results I included sixteen (16) primary studies with twenty-eight thousand five hundred ninety-one (28,591) mothers who gave birth in Ethiopia. The pooled incidence of obstructed labor in Ethiopia was 12.93% (95% CI: 10.44–15.42, I2 = 98.0%, p < 0.001). Out of these, 67.3% (95% CI: 33.32–101.28) did not have antenatal care follow-up, 77.86% (95% CI: 63.07–92.66) were from the rural area, and 58.52% (95% CI: 35.73– 82.31) were referred from health centers and visited hospitals after 12 h of labor. The major causes of obstructed labor were cephalo-pelvic disproportion 64.65% (95% CI: 57.15– 72.14), and malpresentation and malposition in 27.24% (95% CI: 22.05–32.42) of the cases. The commonest complications were sepsis in 38.59% (95% CI: 25.49–51.68), stillbirth in 38.08% (95% CI: 29.55–46.61), postpartum hemorrhage in 33.54% (95% CI:12.06– 55.02), uterine rupture in 29.84% (95% CI: 21.09–38.58), and maternal death in 17.27% (95% CI: 13.47–48.02) of mothers who gave birth in Ethiopia. Conclusion This systematic review and meta-analysis showed that the incidence of obstructed labor was high in Ethiopia. Not having antenatal care follow-up, rural residency, and visiting hospitals after 12 h of labor increased the incidence of obstructed labor. The major causes of obstructed labor were cephalo-pelvic disproportion, and malpresentation and malpresentation. Additionally, the commonest complications were sepsis, stillbirth, postpartum hemorrhage, uterine rupture, and maternal death. Thus, promoting antenatal care service utilization, a good referral system, and availing comprehensive obstetric care in nearby health institutions are recommended to prevent the incidence of obstructed labor and its complications.


2021 ◽  
Author(s):  
Maria de Lourdes de Souza ◽  
Adalia Edna Fernando Chipindo ◽  
Eneida Patrícia Teixeira ◽  
Anna Carolina Raduenz Huf Souza ◽  
Rita de Cássia Teixeira Rangel ◽  
...  

Abstract BackgroundPostpartum hemorrhage (PPH) is the most common form of obstetric hemorrhage. This is the main cause of maternal death around the world: the incidence varies among countries and accounts for 27% (in some countries, more than 50%) of direct obstetric maternal deaths, mainly in the postpartum period. Recognizing risk factors for PPH in prenatal care and during childbirth care is the first stage to prevent maternal death from PPH. The objective this review is: To identify the risk factors for hemorrhage in the third stage of labor described in the literature from 2000 to 2020. MethodsA protocol for a Systematic Review and Meta-analysis study was developed, supported by the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA-P) and, registered in the International Prospective Register of Systematic Reviews (PROSPERO). The research question for conducting the review was structured according to the PEOS strategy (P — Populations/People/Patient/ Problem, E — Exposure (s), O — Outcome, S — Study design): P — women aged from 10 to 49 years, in labor; E — risk factors for hemorrhage in the third stage of labor; O — women with hemorrhage during birth and postpartum; S — observational studies (case control and cohort). Thus, the defined question was: what are the risk factors for hemorrhage in the third stage of labor described in the literature from 2000 to 2020? As for the planning of electronic searches, databases were consulted by using the platform of the Coordination for the Improvement of Higher Education Personnel in Brazil (CAPES, as per its Portuguese acronym). Due to the characteristics of each database, specific search strategies were chosen for each database. After applying the eligibility criteria, the articles that are selected will have the quality of the evidence evaluated by applying the Grading of Recommendations, Assessment, Development and Evaluation (GRADE), with the online tool GRADEpro GDT.Discussion Prevention and control of hemorrhage must be initiated in the prenatal period, requiring competent professionals to carry out the appropriate clinical evaluation to classify the degree of risk to which the woman is exposed. This systematic review will support the studies of professionals who working in Angola and Brazil.Systematic review registrationPROSPERO available from: https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021219303


2021 ◽  
Author(s):  
Margaret Omowaleola Akinwaare ◽  
Oyeninhun Abimbola Oluwatosin ◽  
Olalekan A Uthman ◽  
Elizabeth Ike

Introduction Globally, efforts are being made to reduce the menace of maternal death in order to achieve the sustainable development goal. Maternal death has been associated with inadequate birth preparedness and complication readiness especially in the low and middle income countries. Therefore, this review assessed birth preparedness and complication readiness in Nigeria. Methods A systematic review and meta-analysis of published research articles on birth preparedness and complication readiness in Nigeria was done using PubMed, EMBASE and MEDLINE databases. All published articles from inception to November, 2018 were included in the review. A total of 8913 published articles were identified from electronic search, a total of 4440 studies were included in this review, while only 12 articles met the inclusion criteria and were included in the meta-analysis. Results The pooled prevalence of Good BPCR for all studies yielded an estimate of 58.7% (95% CI 43.9 to 72.7%). The I2 statistic was 98%, indicating statistically significant heterogeneity among the studies. The percentage of women with good birth preparedness and complication readiness increases with increasing year of publication, such that women tended to be more aware good birth preparedness and complication readiness in recent years. More than half of the women had knowledge of obstetric danger signs (52.0%, 95% CI 39.5 to 64.4%, 10 studies), arranged for transportation (59.5%, 95% CI 36.2 to 80.7, 11 studies) or saved money (63.4%, 95% CI 44.7 to 80.2%, 11 studies) as part of the BPCR. Conclusion Women in Nigeria are better prepared for birth preparedness and complication readiness in recent years. Therefore, interventions to promote more adequate birth preparedness and complication readiness among women is recommended.


2017 ◽  
Vol 51 ◽  
pp. 105 ◽  
Author(s):  
Keila Cristina Mascarello ◽  
Bernardo Lessa Horta ◽  
Mariângela Freitas Silveira

OBJECTIVE: The objective of this study was to determine the risks of severe acute maternal complications associated with cesarean section without medical indication. METHODS: A systematic review was carried out with meta-analysis. The literature search was performed systematically, in multiple stages, in the PubMed, Lilacs, and Web of Science databases using the following descriptors: (postpartum period) and (cesarean section or natural childbirth) and ((morbidity or mortality) or (postpartum hemorrhage) or (puerperal infection) or (surgical infection) or (puerperal disorders)). The protocol of the study was registered at PROSPERO as CRD42016032933. A total of 1,328 articles were found; after selection, eight publications that met the study objective and inclusion criteria were selected, with information on 1,051,543 individuals. RESULTS: The results obtained in the meta-analyses indicate that women with cesarean section have a higher chance of maternal death (OR = 3.10, 95%CI 1.92–5.00) and postpartum infection (OR = 2.83, 95%CI, 1.585.06), but they have a lower chance of hemorrhage (OR = 0.52, 95%CI 0.48–0.57). For the blood transfusion outcome, the group effect was not associated with the type of delivery (95%CI 0.88–2.81). CONCLUSIONS: The quality of evidence was considered low for hemorrhage and blood transfusion and moderate for postpartum infection and maternal death. Thus, cesarean sections should be performed with caution and safety, especially when its benefits outweigh the risks of a surgical procedure.


Author(s):  
Jasmine Abu-Amara ◽  
Dawid Szpecht ◽  
Salwan Al-Saad ◽  
Lukasz Karbowski

published from January 1st to 27th of December 2020. Two independent reviewers evaluated studies using the STROBE statement in combination with the CERQual quality assessment of findings. Total 1387 articles were screened and a final 24 studies evaluated (220 1st/2nd trimesters COVID-19 pregnant women). 132/220 (60%) were symptomatic, most commonly with fever (86/220=39%) or cough (73/220=33%). Minority of studies reported complications, notably preeclampsia (2/15 patients-13%). 3 cases of maternal death were reported. Majority of neonates had unreported status concerning the outcome of pregnancy. Neonatal death occurred in 17 cases (including one chemical pregnancy, 5 miscarriages, 2 IUFD, 6 stillbirths and 3 abortions) Majority of reported mothers who contracted COVID-19 during 1st/2nd trimesters are yet to complete their pregnancy. Usually, mothers are discharged from the hospital without any serious complications, however, placental inflammation/fibrin deposition and neonatal death has been reported in a number of cases.


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