BIRTH PREPAREDNESS AND COMPLICATION READINESS OF WOMEN IN NIGERIA: A SYSTEMATIC REVIEW AND META-ANALYSIS

Introduction Globally, efforts are being made to reduce the menace of maternal death in order to achieve the sustainable development goal. Maternal death has been associated with inadequate birth preparedness and complication readiness especially in the low and middle income countries. Therefore, this review assessed birth preparedness and complication readiness in Nigeria. Methods A systematic review and meta-analysis of published research articles on birth preparedness and complication readiness in Nigeria was done using PubMed, EMBASE and MEDLINE databases. All published articles from inception to November, 2018 were included in the review. A total of 8913 published articles were identified from electronic search, a total of 4440 studies were included in this review, while only 12 articles met the inclusion criteria and were included in the meta-analysis. Results The pooled prevalence of Good BPCR for all studies yielded an estimate of 58.7% (95% CI 43.9 to 72.7%). The I2 statistic was 98%, indicating statistically significant heterogeneity among the studies. The percentage of women with good birth preparedness and complication readiness increases with increasing year of publication, such that women tended to be more aware good birth preparedness and complication readiness in recent years. More than half of the women had knowledge of obstetric danger signs (52.0%, 95% CI 39.5 to 64.4%, 10 studies), arranged for transportation (59.5%, 95% CI 36.2 to 80.7, 11 studies) or saved money (63.4%, 95% CI 44.7 to 80.2%, 11 studies) as part of the BPCR. Conclusion Women in Nigeria are better prepared for birth preparedness and complication readiness in recent years. Therefore, interventions to promote more adequate birth preparedness and complication readiness among women is recommended.

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Childbirth at home and associated factors in Ethiopia: a systematic review and meta-analysis

Archives of Public Health ◽

10.1186/s13690-021-00569-5 ◽

2021 ◽

Vol 79 (1) ◽

Author(s):

Asteray Assmie Ayenew ◽

Azezu Asres Nigussie ◽

Biruk Ferede Zewdu

Keyword(s):

Systematic Review ◽

Odds Ratio ◽

Associated Factors ◽

Meta Analysis ◽

Birth Preparedness ◽

Media Access ◽

Complication Readiness ◽

Poor Knowledge ◽

Pooled Prevalence ◽

At Home

Abstract Background Maternal mortality remains a major challenge to health systems worldwide. Although most pregnancies and births are uneventful, approximately 15% of all pregnant women develop potentially life-threatening complications. Childbirth at home in this context can be acutely threatening, particularly in developing countries where emergency care and transportation are less available. Therefore, this systematic review and meta-analysis aimed to assess the prevalence of home childbirth and its associated factors among women in Ethiopia at their last childbirth. Method For this review, we used the standard PRISMA checklist guideline. This search included all published and unpublished observational studies written only in English language and conducted in Ethiopia. PubMed/Medline, Hinari, EMBASE, Google Scholar, Science Direct, Scopus, Web of Science (WoS), ProQuest, Cochrane Library, African Journals Online, Ethiopian’s university research repository online library were used. Based on the adapted PICO principles, different search terms were applied to achieve and access the essential articles from February 1–30, 2020. The overall selected search results were 40 studies. Microsoft Excel was used for data extraction and Stata version 11.0 (Stata Corporation, College Station, Texas, USA) for data analysis. The quality of individual studies was appraised by using the Joanna Briggs Institute (JBI) quality appraisal checklist. The heterogeneity of the studies was assessed by the Cochrane Q and I2 test. With the evidence of heterogeneity, subgroup analysis and sensitivity analysis were computed. The pooled prevalence of childbirth at home and the odds ratio (OR) with a 95% confidence interval was presented using forest plots. Result Seventy-one thousand seven hundred twenty-four (71, 724) mothers who gave at least one birth were recruited in this study. The estimated prevalence of childbirth at home in Ethiopia was 66.7% (95%CI: 61.56–71.92, I2 = 98.8%, p-value < 0.001). Being from a rural area (adjusted odds ratio (AOR) 6.48, 95% confidence interval (CI): 3.48–12.07), being uneducated (AOR = 5.90, 95% CI: 4.42–7.88), not pursuing antenatal (ANC) visits at all (AOR = 4.57(95% CI: 2.42–8.64), having 1–3 ANC visits only (AOR = 4.28, 95% CI: 3.8–8.26), no birth preparedness and complication readiness plan (AOR = 5.60, 95% CI: 6.68–8.25), no media access (AOR = 3.46, 95% CI: 2.27–5.27), having poor knowledge of obstetric complications (AOR = 4.16: 95% CI: 2.84–6.09), and walking distance more than 2 hours to reach the nearest health facility (AOR = 5.12, 95% CI: 2.94–8.93) were the factors associated with giving childbirth at home. Conclusion The pooled prevalence of childbirth at home was high in Ethiopia. Being from a rural area, being uneducated, not pursuing ANC visits at all, having 1–3 ANC visits only, no media access, having poor knowledge of obstetric complications, not having a birth preparedness and complication readiness plan, and walking time greater than 2 hours to reach the nearest health facility increased the probability of childbirth at home in Ethiopia.

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Male involvement in birth preparedness and complication readiness in Ethiopia: A Systematic review and Meta-analysis

10.21203/rs.3.rs-55935/v2 ◽

2020 ◽

Author(s):

Chilot kassa Mekonnen ◽

Hailemichael Kindie Abate ◽

Negesu Gizaw Demessie

Keyword(s):

Systematic Review ◽

Low Income ◽

Meta Analysis ◽

Random Effect ◽

Random Effect Model ◽

Male Involvement ◽

Outcome Variable ◽

Birth Preparedness ◽

Complication Readiness ◽

Pooled Prevalence

Abstract Background: Male involvement during pregnancy, labor and post-partum care has been shown to improve positive maternal and newborn outcomes. Nevertheless, it continues to be low, especially in low income countries. One of the reasons is the lack of birth preparedness and complication readiness, which is recognized as the most cost-effective and achievable components of safe motherhood programs around the world. Thus, this systematic review and meta-analysis study tried to determine the pooled prevalence of male involvement in birth preparedness and complication readiness (BP/CR) and its associated factors in Ethiopia. Methods: Searching of the primary articles was completed by PubMed/MEDLINE, EMBASE, CINAHAL, and Google Scholar, HINARI portal which includes the SCOPUS, African Index Medicus, and African Journals Online Database. The data was extracted by using a standard data extraction checklist that developed according to Joanna Briggs Institute (JBI).For assessing heterogeneity across the studies I2 statistics was used. The Funnel plot asymmetry and Egger’s tests were used to check the presence of publication bias. A random effect model was used to estimate the pooled proportion of male involvement. Odds Ratio (OR) with the 95% confidence interval was also used to determine the association of identified factors with the outcome variable. Result: From a total of 614, primary studies 8 were eligible for inclusion in the final systematic Review and meta-analysis. The pooled estimate of male involvement in birth preparedness and complication readiness was found to be 40.17% [95%CI (24.01-56.33). Conclusion: The pooled prevalence of male involvement in birth preparedness and complication readiness was relatively low. Thus, Minister of Health with its stake holders better to give emphasis on community awareness programs so as to increase male involvement for birth preparedness and complication readiness.

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Male involvement in Birth Preparedness and Complication Readiness in Ethiopia: A Systematic Review and Meta-analysis

10.21203/rs.3.rs-55935/v1 ◽

2020 ◽

Author(s):

Chilot kassa Mekonnen ◽

Hailemichael Kindie Abate ◽

Negesu Gizaw Demessie

Keyword(s):

Systematic Review ◽

Low Income ◽

Post Partum ◽

Meta Analysis ◽

Random Effect Model ◽

Male Involvement ◽

Outcome Variable ◽

Birth Preparedness ◽

Complication Readiness ◽

Pooled Prevalence

Abstract Background: Maternal death may occur from complications while a woman is pregnant, during labor and post-partum period. Birth preparedness and complication readiness during pregnancy period prominently increase positive maternal as well as child health outcomes. Male involvement in pregnancy, labor and post-partum care has been shown to improve maternal and newborn outcomes. Nevertheless, it continues to be low, especially in low income countries. One of the reasons is the lack of birth preparedness and complication readiness, which is recognized as the most cost-effective and achievable components of safe motherhood programs around the world. Thus, this systematic review and meta-analysis study tried to determine the pooled prevalence of male involvement in birth preparedness and complication readiness (BP/CR) and its associated factors in Ethiopia. Methods: Searching of the primary articles was completed by PubMed/MEDLINE, EMBASE, CINAHAL, and Google Scholar, HINARI portal which includes the SCOPUS, African Index Medicus, and African Journals Online Database. The data was extracted by using a standard data extraction checklist that developed according to Joanna Briggs Institute (JBI).For assessing heterogeneity across the studies I2 statistics was used. The Funnel plot asymmetry and Egger’s tests were used to check the presence of publication bias. A random effect model was used to estimate the pooled prevalence of male involvement in birth preparedness and complication readiness. Odds Ratio (OR) with the 95% confidence interval was also used to determine the association of identified factors with the outcome variable. Statistical analysis was conducted using STATA version 11 software.Result: From a total of 614, primary studies with (sample participants 3413), 8 were eligible for inclusion in the final systematic Review and meta-analysis. The pooled estimate of male involvement in birth preparedness and complication readiness was found to be 40.17% [95%CI (24.01-56.33) Conclusion: The pooled prevalence of male involvement in birth preparedness and complication readiness was relatively low. Thus, Minister of Health with its stake holders better to give emphasis on community awareness programs so as to increase male involvement for birth preparedness and complication readiness.

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Global variation in the prevalence and incidence of major depressive disorder: a systematic review of the epidemiological literature

Psychological Medicine ◽

10.1017/s0033291712001511 ◽

2012 ◽

Vol 43 (3) ◽

pp. 471-481 ◽

Cited By ~ 428

Author(s):

A. J. Ferrari ◽

A. J. Somerville ◽

A. J. Baxter ◽

R. Norman ◽

S. B. Patten ◽

...

Keyword(s):

Systematic Review ◽

Major Depressive Disorder ◽

Depressive Disorder ◽

Meta Analysis ◽

Significant Heterogeneity ◽

Major Depressive ◽

Middle Income ◽

Pooled Prevalence ◽

Low Middle Income Countries ◽

Incidence Studies

BackgroundSummarizing the epidemiology of major depressive disorder (MDD) at a global level is complicated by significant heterogeneity in the data. The aim of this study is to present a global summary of the prevalence and incidence of MDD, accounting for sources of bias, and dealing with heterogeneity. Findings are informing MDD burden quantification in the Global Burden of Disease (GBD) 2010 Study.MethodA systematic review of prevalence and incidence of MDD was undertaken. Electronic databases Medline, PsycINFO and EMBASE were searched. Community-representative studies adhering to suitable diagnostic nomenclature were included. A meta-regression was conducted to explore sources of heterogeneity in prevalence and guide the stratification of data in a meta-analysis.ResultsThe literature search identified 116 prevalence and four incidence studies. Prevalence period, sex, year of study, depression subtype, survey instrument, age and region were significant determinants of prevalence, explaining 57.7% of the variability between studies. The global point prevalence of MDD, adjusting for methodological differences, was 4.7% (4.4–5.0%). The pooled annual incidence was 3.0% (2.4–3.8%), clearly at odds with the pooled prevalence estimates and the previously reported average duration of 30 weeks for an episode of MDD.ConclusionsOur findings provide a comprehensive and up-to-date profile of the prevalence of MDD globally. Region and study methodology influenced the prevalence of MDD. This needs to be considered in the GBD 2010 study and in investigations into the ecological determinants of MDD. Good-quality estimates from low-/middle-income countries were sparse. More accurate data on incidence are also required.

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Male partners’ participation in birth preparedness and complication readiness in low- and middle-income countries: a systematic review and meta-analysis

BMC Pregnancy and Childbirth ◽

10.1186/s12884-021-03994-0 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Minyahil Tadesse Boltena ◽

Abraham Sahlemichael Kebede ◽

Ziad El-Khatib ◽

Benedict Oppong Asamoah ◽

Andualem Tadesse Boltena ◽

...

Keyword(s):

Systematic Review ◽

Meta Analysis ◽

Random Effect ◽

Birth Preparedness ◽

Male Partners ◽

Complication Readiness ◽

Middle Income ◽

Middle Income Countries ◽

Study Participants ◽

Low And Middle Income

Abstract Background Maternal and neonatal health outcomes remain a challenge in low- and middle-income countries (LMICs) despite priority given to involving male partners in birth preparedness and complication readiness (BPCR). Men in LMICs often determine women’s access to and affordability of health services. This systematic review and meta-analysis determined the pooled magnitude of male partner’s participation in birth preparedness and complication readiness in LMICs. Methods Literature published in English language from 2004 to 2019 was retrieved from Google Scholar, PubMed, CINAHL, Scopus, and EMBASE databases. The Joanna Briggs Institute’s critical appraisal tool for prevalence and incidence studies were used. A pooled statistical meta-analysis was conducted using STATA Version 14.0. The heterogeneity and publication bias were assessed using the I2 statistics and Egger’s test. Duval and Tweedie's nonparametric trim and fill analysis using the random-effect analysis was carried out to validate publication bias and heterogeneity. The random effect model was used to estimate the summary prevalence and the corresponding 95% confidence interval (CI) of birth preparedness and complication readiness. The review protocol has been registered in PROSPERO number CRD42019140752. The PRISMA flow chart was used to show the number of articles identified, included, and excluded with justifications described. Results Thirty-seven studies with a total of 17, 148 participants were included. The pooled results showed that 42.4% of male partners participated in BPCR. Among the study participants, 54% reported having saved money for delivery, whereas 44% identified skilled birth attendants. 45.8% of male partners arranged transportation and 57.2% of study participants identified health facility as a place of birth. Only 16.1% of the male partners identified potential blood donors. Conclusions A low proportion of male partners were identified to have participated in BPCR in LMICs. This calls countries in low- and middle-income setting for action to review their health care policies, to remove the barriers and promote facilitators to male partner’s involvement in BPCR. Health systems in LMICs must design and innovate scalable strategies to improve male partner’s arrangements for a potential blood donor and transportation for complications that could arise during delivery or postpartum haemorrhage.

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The high risk of malarial recurrence in patients with Plasmodium-mixed infection after treatment with antimalarial drugs: a systematic review and meta-analysis

Parasites & Vectors ◽

10.1186/s13071-021-04792-5 ◽

2021 ◽

Vol 14 (1) ◽

Author(s):

Aongart Mahittikorn ◽

Frederick Ramirez Masangkay ◽

Kwuntida Uthaisar Kotepui ◽

Giovanni De Jesus Milanez ◽

Manas Kotepui

Keyword(s):

Systematic Review ◽

Mixed Infection ◽

Subgroup Analysis ◽

Initial Treatment ◽

Meta Analysis ◽

Antimalarial Drugs ◽

Secondary Outcome ◽

Significant Heterogeneity ◽

Pooled Prevalence ◽

Significant Difference

Abstract Background Malaria mixed infections are often unrecognized by microscopists in the hospitals, and a delay or failure to treat Plasmodium-mixed infection may lead to aggravated morbidity and increased mortality. The present study aimed to quantify the pooled proportion and risk of malarial recurrences after the treatment of Plasmodium-mixed infection. The results of the study may provide benefits in the management of Plasmodium-mixed infection in co-endemic regions. Methods This systematic review and meta-analysis searched the international Prospective Register of Systematic Reviews (PROSPERO; ID = CRD42020199709), MEDLINE, Web of Science, and Scopus for potentially relevant studies in any language published between January 1, 1936, and July 20, 2020, assessing drug efficacy in patients with Plasmodium-mixed infection. The primary outcome was the pooled prevalence of Plasmodium parasitemia after initiating antimalarial treatment for Plasmodium-mixed infection. The secondary outcome was the pooled risk ratio (RR) of malarial recurrence in Plasmodium-mixed infection compared with those in Plasmodium falciparum and Plasmodium vivax mono-infection. The pooled analyses were calculated by random-effects meta-analysis. After the initial treatment in different days of recurrences (≤ 28 days or > 28 days), the risk of Plasmodium parasitemia was compared in subgroup analysis. Results Out of 5217 screened studies, 11 were included in the meta-analysis, including 4390 patients from six countries. The pooled prevalence of all recurrences of Plasmodium-mixed parasitemia was 30% (95% confidence interval (CI) 16–43; I2: 99.2%; 11 studies). The RR of malarial recurrence within 28 days after the initial treatment (clinical treatment failure) of Plasmodium-mixed parasitemia compared with the treatment of P. falciparum was 1.22 (p: 0.029; 95% CI 1.02–1.47; Cochran Q: 0.93; I2: 0%; six studies), while there was no significant difference in the risk of recurrence 28 days after initial treatment compared with the treatment of P. falciparum (p: 0.696, RR: 1.14; 95% CI 0.59–2.18; Cochran Q < 0.05; I2: 98.2%; four studies). The subgroup analysis of antimalarial drugs showed that significant malarial recurrence within 28 days was observed in patients treated with artemisinin-based combination therapies (ACTs) with no significant heterogeneity (p: 0.028, RR: 1.31; 95% CI 1.03–1.66; Cochran Q: 0.834; I2: 0%). Conclusions The present findings showed a high prevalence of malarial recurrence after the initial treatment of Plasmodium-mixed infection. Moreover, significant malaria recurrence of mixed infection occurred within 28 days after treatment with ACTs. Graphic Abstract

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The prevalence of personality disorders in the community: a global systematic review and meta-analysis

The British Journal of Psychiatry ◽

10.1192/bjp.2019.166 ◽

2019 ◽

Vol 216 (2) ◽

pp. 69-78 ◽

Cited By ~ 9

Author(s):

Catherine Winsper ◽

Ayten Bilgin ◽

Andrew Thompson ◽

Steven Marwaha ◽

Andrew M. Chanen ◽

...

Keyword(s):

Personality Disorder ◽

Personality Disorders ◽

Study Design ◽

Large Scale ◽

Meta Analysis ◽

High Income ◽

Significant Heterogeneity ◽

Prevalence Rates ◽

Middle Income ◽

Pooled Prevalence

BackgroundPersonality disorders are now internationally recognised as a mental health priority. Nevertheless, there are no systematic reviews examining the global prevalence of personality disorders.AimsTo calculate the worldwide prevalence of personality disorders and examine whether rates vary between high-income countries and low- and middle-income countries (LMICs).MethodWe systematically searched PsycINFO, MEDLINE, EMBASE and PubMed from January 1980 to May 2018 to identify articles reporting personality disorder prevalence rates in community populations (PROSPERO registration number: CRD42017065094).ResultsA total of 46 studies (from 21 different countries spanning 6 continents) satisfied inclusion criteria. The worldwide pooled prevalence of any personality disorder was 7.8% (95% CI 6.1–9.5). Rates were greater in high-income countries (9.6%, 95% CI 7.9–11.3%) compared with LMICs (4.3%, 95% CI 2.6–6.1%). In univariate meta-regressions, significant heterogeneity was partly attributable to study design (two-stage v. one-stage assessment), county income (high-income countries v. LMICs) and interview administration (clinician v. trained graduate). In multiple meta-regression analysis, study design remained a significant predictor of heterogeneity. Global rates of cluster A, B and C personality disorders were 3.8% (95% CI 3.2, 4.4%), 2.8% (1.6, 3.7%) and 5.0% (4.2, 5.9%).ConclusionsPersonality disorders are prevalent globally. Nevertheless, pooled prevalence rates should be interpreted with caution due to high levels of heterogeneity. More large-scale studies with standardised methodologies are now needed to increase our understanding of population needs and regional variations.

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Prevalence and progression of incidental terminal ileitis on non-diagnostic colonoscopy: a systematic review and meta-analysis

Journal of Crohn s and Colitis ◽

10.1093/ecco-jcc/jjab030 ◽

2021 ◽

Author(s):

Manasi Agrawal ◽

Mario Bento-Miranda ◽

Samantha Walsh ◽

Neeraj Narula ◽

Jean-Frederic Colombel ◽

...

Keyword(s):

Systematic Review ◽

Prevalence Rate ◽

Meta Analysis ◽

Significant Heterogeneity ◽

Long Term Outcomes ◽

Diagnostic Colonoscopy ◽

Terminal Ileitis ◽

Pooled Prevalence

Abstract Background Incidentally-diagnosed terminal ileitis (IDTI) has been reported among asymptomatic persons undergoing non-diagnostic colonoscopy. The purpose of our study was to determine the prevalence and long-term outcomes of asymptomatic terminal ileitis. Methods We performed a systematic review using three biomedical databases (Medline, Embase and Web of Science) and relevant scientific meeting abstracts. We identified observational studies that reported the prevalence of IDTI in adults undergoing screening or polyp surveillance colonoscopy and/or the long-term outcomes of such lesions. A random-effects meta-analysis was conducted to determine the pooled prevalence rate of IDTI. The progression of IDTI to overt Crohn’s disease (CD) was also described. Results Of 2,388 eligible studies, 1,784 were screened after excluding duplicates, 84 were reviewed in full text, and 14 studies were eligible for inclusion. Seven studies reported the prevalence of IDTI in 44,398 persons undergoing non-diagnostic colonoscopy, six studies reported follow-up data, and one study reported both types of data. The pooled prevalence rate of IDTI was 1.6% (CI 0.1–21.8%) with significant heterogeneity (I 2 = 99.7). Among patients who had undergone non-diagnostic colonoscopy and had follow-up data (range 13–84 months reported in five studies), progression to overt CD was rare. Conclusion IDTI is not uncommon on non-diagnostic colonoscopies. Based on limited data, the rate of its progression to overt CD seems low, and watchful waiting is likely a reasonable strategy. Further long-term follow-up studies are needed to inform the natural history of incidental terminal ileitis, factors that predict progression to CD, and therapeutic implications.

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Prevalence of idiopathic REM behavior disorder: a systematic review and meta-analysis

SLEEP ◽

10.1093/sleep/zsaa294 ◽

2021 ◽

Author(s):

Calogero Edoardo Cicero ◽

Loretta Giuliano ◽

Jaime Luna ◽

Mario Zappia ◽

Pierre-Marie Preux ◽

...

Keyword(s):

Systematic Review ◽

Subgroup Analysis ◽

Meta Analysis ◽

Random Effect Model ◽

Behavior Disorder ◽

Significant Heterogeneity ◽

Pooled Prevalence ◽

Screening Questionnaires ◽

Meta Regression

Abstract Study Objectives To provide an overall estimate of the prevalence of idiopathic REM Sleep Behavior Disorder (iRBD). Methods Two investigators have independently searched the PubMed and Scopus databases for population-based studies assessing the prevalence of iRBD. Data about type of diagnosis (polysomnographic diagnosis, defined iRBD [dRBD]; clinical diagnosis, probable RBD [pRBD]), continent, age range of the screened population, quality of the studies, sample size, screening questionnaires and strategies have been gathered. A random effect model was used to estimate the pooled prevalence. Heterogeneity was investigated with subgroup analysis and meta-regression. Results From 857 articles found in the databases, 19 articles were selected for the systematic review and meta-analysis. According to the type of diagnosis, five studies identified dRBD cases given a pooled prevalence of 0.68% (95%CI 0.38-1.05) without significant heterogeneity (Cochran’s Q p=0.11; I 2 = 46.43%). Fourteen studies assessed the prevalence of pRBD with a pooled estimate of 5.65% (95%CI 4.29-7.18) and a significant heterogeneity among the studies (Cochran’s Q p<0.001; I 2 = 98.21%). At the subgroup analysis, significant differences in terms of prevalence were present according to the quality of the studies and, after removing two outlaying studies, according to the continents and the screening questionnaire used. Meta-regression did not identify any significant effect of the covariates on the pooled estimates. Conclusion Prevalence estimates of iRBD are significantly impacted by diagnostic level of certainty. Variations in pRBD prevalence are due to methodological differences in study design and screening questionnaires employed.

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The prevalence of thrombocytopenia and leucopenia among people living with HIV/AIDS in Ethiopia: A systematic review and meta-analysis

PLoS ONE ◽

10.1371/journal.pone.0257630 ◽

2021 ◽

Vol 16 (9) ◽

pp. e0257630

Author(s):

Habtye Bisetegn ◽

Hussien Ebrahim

Keyword(s):

Systematic Review ◽

Meta Analysis ◽

Hematological Parameters ◽

Random Effect ◽

People Living With Hiv ◽

Significant Heterogeneity ◽

Aids Patients ◽

Pooled Prevalence ◽

Living With Hiv ◽

Hiv Aids

Introduction Thrombocytopenia and leucopenia are frequently encountered hematological disorders among people living with HIV/AIDS. This systematic review and meta-analysis were aimed to indicate the national prevalence of thrombocytopenia and leucopenia among HIV/AIDS patients. Methods This systematic review and meta-analysis was conducted following the preferred reporting items for systematic review and meta-analysis (PRISMA) guidelines. A systematic search was conducted from February 01, 2021 to April 02, 2021 using electronic databases Google Scholar, PubMed, Web of Sciences, Google, EMBASE, SCOPUS and ResearchGate. The quality of the included studies was assessed using Newcastle—Ottawa Quality Assessment Scale (NOS) adapted for cross-sectional studies. Data analysis was done using STATA version 14 using metan commands. Random effect meta-analysis was used to estimate the pooled prevalence of thrombocytopenia and leucopenia among people living with HIV/AIDS in Ethiopia. Result Of the 349 initially searched articles, 90 were assessed for eligibility and only 13 articles published from 2014 to 2020 were included in the final meta-analysis. A total of 3854 participants were involved in the included studies. The pooled prevalence of thrombocytopenia was 9.69% (95%CI; 7.40–11.97%). Significant heterogeneity was observed with I2 value of 84.7%. Thrombocytopenia was 11.91% and 5.95% prevalent among HAART naive and HAART exposed HIV/AIDS patients, respectively. The pooled prevalence of leucopenia among HIV/AIDS patients was 17.31% (95%CI: 12.37–22.25%). Conclusion This study showed a high prevalence of thrombocytopenia and leucopenia among people living with HIV/AIDS, indicating the necessity of regular screening of HIV seropositive patients for different hematological parameters and providing treatment.

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