scholarly journals Medication Adherence and Associated Factors in Patients With Type 2 Diabetes: A Structural Equation Model

2021 ◽  
Vol 9 ◽  
Author(s):  
Jing Huang ◽  
Shenglan Ding ◽  
Shuyuan Xiong ◽  
Zhiping Liu

Background: The number of patients with type 2 diabetes (T2D) is increasing. Medication treatment is of great importance to stabilize blood glucose. Previous studies have reported that neuroticism, self-efficacy, and social support are factors associated with medication adherence, but few studies have fully investigated the mechanisms between these factors and medication adherence in patients with T2D.Purpose: To explore the prevalence of medication adherence and the factors associated with medication adherence in patients with T2D.Methods: A cross-sectional study consisting of 483 patients with T2D was conducted from July to December 2020. Questionnaires containing sociodemographic and clinical characteristics, the Morisky Medication Adherence Scale-8 (MMAS-8), the neuroticism subscale of the Eysenck Personality Questionnaire-Revised Short Scale (EPQ-RS), the Multidimensional Scale of Perceived Social Support (MSPSS), and the Diabetes Management Self-efficacy Scale (DMSES) were used to collect data. The structural equation model (SEM) was used to test the hypotheses.Results: This study included 305 (63.1%) medication adherence and 178 (36.9%) medication non-adherence patients with T2D. Social support directly influenced medication adherence (β = 0.115, P = 0.029) and indirectly influenced medication adherence through self-efficacy (β = 0.044, P = 0.016). Self-efficacy directly influenced medication adherence (β = 0.139, P = 0.023). Neuroticism indirectly affected medication adherence through social support (β = −0.027, P = 0.023) and self-efficacy (β = −0.019, P = 0.014). Moreover, there was a sequential mediating effect of social support and self-efficacy on the relationship between neuroticism and medication adherence (β = −0.010, P = 0.012). After controlling for age and gender, similar results were obtained. The model fit indices showed a good fit.Conclusions: The medication adherence of patients with T2D needs to be improved. Neuroticism, social support, and self-efficacy had direct or indirect effects on medication adherence in patients with T2D. Healthcare providers should comprehensively develop intervention programs based on neuroticism, social support, and self-efficacy to improve medication adherence in patients with T2D.

2020 ◽  
Author(s):  
Qinghua Zhang ◽  
Feifei Huang ◽  
Lei Zhang ◽  
Shasha Li ◽  
Jingping Zhang

Abstract Background Considering the High Blood Pressure-Health Literacy (HBP-HL) has not been included in the study of Health-Related Quality of Life (HRQoL). The synergistic effects and the potential mechanism HBP-HL, self-management behavior, medication adherence, self-efficacy, social support on HRQoL remain unclear. This study aimed to introduce the conception of HBP-HL, and develop a structural equation model to identify the factors influencing of the HRQoL among Kazakh hypertensive patients. Methods A cross-sectional investigation study was conducted to collect data. Patients with hypertension were recruited through random cluster sampling in Kazakh settlements in Urumqi County, Xinjiang. The one-on-one household interviews were conducted by Kazakh investigators. The questionnaires regarding HBP-HL, HRQoL, self-management behavior, medication adherence, self-efficacy, and social support were collected. In addition, the results of physical examination were also included. A structural equation model was used to assess the association between the measured factors and HRQoL. Results 516 Kazakh patients were recruited, and 94.4% of them had a relatively low HBP-HL score. The mean standardized scores of HRQoL, self-management, medication adherence were poor; they were 63.5, 66.2, and 64.4, respectively. But 96.1% and 98.3% of the participants had high levels of self-efficacy and social support. The structural equation model of the HRQoL had a good overall fit (χ2/df = 2.078, AGFI = 0.944, GFI = 0.968, CFI = 0.947, IFI = 0.949, RMSEA = 0.046). The model indicated that the HBP-HL has the highest correlation with HRQoL, following with self-management behavior, social support, and self-efficacy. Conclusions Evidence from this study demonstrates that low HBP-HL is a major influenced factor of HRQoL among Kazakh hypertensive patients. Future programs should consider HBP-HL as the breakthrough point when designing targeting intervention strategies for Kazakh hypertension patients. Firstly, researchers should give a priority to evaluate patient’s HBP-HL before intervention. Next, tailored interventions are implemented for patients, and and ultimately it will contribute to control blood pressure and improve patients’ HRQoL.


2020 ◽  
Vol 35 (6) ◽  
pp. E18-E24
Author(s):  
Lakeshia Cousin ◽  
Harleah Buck ◽  
Bryan Benitez ◽  
Paul Mills ◽  
Laura Redwine

2020 ◽  
Vol 15 (2) ◽  
Author(s):  
Hema Malini ◽  
Fitra Yeni ◽  
Cindy Ayu Pratiwi ◽  
Devia Putri Lenggogeni

<span lang="EN-US">Patients with diabetes mellitus have difficulties in managing their disease. Most of patients with uncontrolled diabetes have HbA1c &gt; 9%. This study aimed to determine the factors associated with self-management of type 2 diabetes mellitus patients with HbA1c&gt; 9% in Public Health Center, Padang 2019. This study used a cross-sectional design. The sampling technique using a total sampling technique with a total sample of 79 respondents. This study used a questionnaire that consists of questionnaires; DKQ, DMSES, S4-MAD, and SDSCA-revised. Data were analyzed using the Pearson Product Moment Correlation test. This study showed, knowledge (mean= 10.89), self-efficacy (mean= 50.01), social support (mean= 52.27), and self-management (mean= 48.38 ). The factors associated with self-management of type 2 diabetes mellitus patients with HbA1c&gt; 9%, are knowledge (p = 0.016), self-efficacy (p = 0.000), and social support (p = 0.001). The most dominant factor in self-management of diabetes patients is self-efficacy (p-value = 0.000), (r = 0.607), and (r2 = 0.3684). Based on the study, it is recommended for health workers to be able to increase their attention to type 2 patients diabetes mellitus patient who have HbA1c&gt; 9% to improve their efficacy in self-management so that patients can control blood </span>


2016 ◽  
Vol 4 (1) ◽  
pp. e000231 ◽  
Author(s):  
Andres Roman-Urrestarazu ◽  
Faleh Mohamed Hussain Ali ◽  
Husein Reka ◽  
Matthew J Renwick ◽  
Gabriela D Roman ◽  
...  

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