scholarly journals Genetic Risk Factors for Alzheimer's Disease in Racial/Ethnic Minority Populations in the U.S.: A Scoping Review

2021 ◽  
Vol 9 ◽  
Author(s):  
Lindsey Rubin ◽  
Lucy A. Ingram ◽  
Nicholas V. Resciniti ◽  
Brianna Ashford-Carroll ◽  
Katherine Henrietta Leith ◽  
...  
Keyword(s):  
Risk Factors ◽  
Ethnic Minority ◽  
Ethnic Minorities ◽  
Scoping Review ◽  
Genetic Risk ◽  
Genetic Risk Factors ◽  
Minority Populations ◽  
Ethnic Minority Populations ◽  
Racial Ethnic ◽  
The U.S

Objectives: As the United States (U.S.) population rapidly ages, the incidence of Alzheimer's Disease and Related Dementias (ADRDs) is rising, with racial/ethnic minorities affected at disproportionate rates. Much research has been undertaken to test, sequence, and analyze genetic risk factors for ADRDs in Caucasian populations, but comparatively little has been done with racial/ethnic minority populations. We conducted a scoping review to examine the nature and extent of the research that has been published about the genetic factors of ADRDs among racial/ethnic minorities in the U.S.Design: Using an established scoping review methodological framework, we searched electronic databases for articles describing peer-reviewed empirical studies or Genome-Wide Association Studies that had been published 2005–2018 and focused on ADRD-related genes or genetic factors among underrepresented racial/ethnic minority population in the U.S.Results: Sixty-six articles met the inclusion criteria for full text review. Well-established ADRD genetic risk factors for Caucasian populations including APOE, APP, PSEN1, and PSEN2 have not been studied to the same degree in minority U.S. populations. Compared to the amount of research that has been conducted with Caucasian populations in the U.S., racial/ethnic minority communities are underrepresented.Conclusion: Given the projected growth of the aging population and incidence of ADRDs, particularly among racial/ethnic minorities, increased focus on this important segment of the population is warranted. Our review can aid researchers in developing fundamental research questions to determine the role that ADRD risk genes play in the heavier burden of ADRDs in racial/ethnic minority populations.

scholarly journals Representation of racial and ethnic minority groups in cohort studies evaluating risk factors for dementia: protocol for a scoping review

BMJ Open ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. e044404
Author(s):  
Arjun Krishnan ◽  
Louise M Waite ◽  
Fiona F Stanaway
Keyword(s):  
Risk Factors ◽  
Cohort Studies ◽  
Ethnic Minority ◽  
Scoping Review ◽  
Primary Data ◽  
Minority Populations ◽  
Minority Representation ◽  
Ethnic Minority Populations ◽  
Racial Ethnic ◽  
Racial And Ethnic Minority

IntroductionAvailable evidence suggests that some racial/ethnic minority populations may be disproportionately burdened by dementia. Cohort studies are an important tool for defining and understanding the causes behind these racial and ethnic inequalities. However, ethnic minority populations may be more likely to be excluded from such research. Therefore, the aim of this study is to systematically investigate and quantify racial and ethnic minority representation in dementia risk factor research.Methods and analysisThe elements of this protocol have been designed in accordance with the relevant sections of the Preferred Reporting Items for Systematic Reviews and Meta-Analysis Protocols which are specifically applicable to scoping review protocols. We will include population-based cohort studies looking at risk factors for dementia incidence in our review and assess the representation of racial and ethnic minority populations in these studies. We will use multiple strategies to identify relevant studies, including a systematic search of the following electronic databases: MEDLINE (Ovid SP), Embase (Ovid SP) and Scopus. Two review authors will independently perform title and abstract screening, full-text screening and data extraction. Included cohort studies will be evaluated using a comprehensive framework to assess racial/ethnic minority representation. Logistic regression will also be performed to describe associations between cohort study characteristics and outcomes related to racial and ethnic minority representation.Ethics and disseminationFormal ethical approval is not required to conduct this review as no primary data are to be collected. The final results of this scoping review will be disseminated through publication in peer-reviewed journals and conference presentations.

scholarly journals Protection of Racial/Ethnic Minority Populations During an Influenza Pandemic

2009 ◽  
Vol 99 (S2) ◽  
pp. S261-S270 ◽  
Author(s):  
Sonja S. Hutchins ◽  
Kevin Fiscella ◽  
Robert S. Levine ◽  
Danielle C. Ompad ◽  
Marian McDonald
Keyword(s):  
Ethnic Minority ◽  
Influenza Pandemic ◽  
Minority Populations ◽  
Ethnic Minority Populations ◽  
Racial Ethnic

Effects of Full-Day Kindergarten on the Long-Term Health Prospects of Children in Low-Income and Racial/Ethnic-Minority Populations

2014 ◽  
Vol 46 (3) ◽  
pp. 312-323 ◽  
Author(s):  
Robert A. Hahn ◽  
Veda Rammohan ◽  
Benedict I. Truman ◽  
Bobby Milstein ◽  
Robert L. Johnson ◽  
...  
Keyword(s):  
Ethnic Minority ◽  
Low Income ◽  
Minority Populations ◽  
Full Day Kindergarten ◽  
Ethnic Minority Populations ◽  
Full Day ◽  
Racial Ethnic

scholarly journals The Intersection of Rural Residence and Minority Race/Ethnicity in Cancer Disparities in the United States

2021 ◽  
Vol 18 (4) ◽  
pp. 1384
Author(s):  
Whitney E. Zahnd ◽  
Cathryn Murphy ◽  
Marie Knoll ◽  
Gabriel A. Benavidez ◽  
Kelsey R. Day ◽  
...  
Keyword(s):  
Access To Care ◽  
Ethnic Minority ◽  
Data Access ◽  
The United States ◽  
Cancer Disparities ◽  
Treatment Modalities ◽  
Minority Populations ◽  
Race Ethnicity ◽  
Ethnic Minority Populations ◽  
Racial Ethnic

One in every twenty-five persons in America is a racial/ethnic minority who lives in a rural area. Our objective was to summarize how racism and, subsequently, the social determinants of health disproportionately affect rural racial/ethnic minority populations, provide a review of the cancer disparities experienced by rural racial/ethnic minority groups, and recommend policy, research, and intervention approaches to reduce these disparities. We found that rural Black and American Indian/Alaska Native populations experience greater poverty and lack of access to care, which expose them to greater risk of developing cancer and experiencing poorer cancer outcomes in treatment and ultimately survival. There is a critical need for additional research to understand the disparities experienced by all rural racial/ethnic minority populations. We propose that policies aim to increase access to care and healthcare resources for these communities. Further, that observational and interventional research should more effectively address the intersections of rurality and race/ethnicity through reduced structural and interpersonal biases in cancer care, increased data access, more research on newer cancer screening and treatment modalities, and continued intervention and implementation research to understand how evidence-based practices can most effectively reduce disparities among these populations.

scholarly journals Evaluation of Revised US Preventive Services Task Force Lung Cancer Screening Guideline Among Women and Racial/Ethnic Minority Populations

2021 ◽  
Vol 4 (1) ◽  
pp. e2033769
Author(s):  
Thomas J. Reese ◽  
Chelsey R. Schlechter ◽  
Lindsey N. Potter ◽  
Kensaku Kawamoto ◽  
Guilherme Del Fiol ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Screening ◽  
Ethnic Minority ◽  
Task Force ◽  
Preventive Services ◽  
Lung Cancer Screening ◽  
Minority Populations ◽  
Screening Guideline ◽  
Ethnic Minority Populations ◽  
Racial Ethnic
Sign in / Sign up

Export Citation Format

Share Document