scholarly journals Immune response for live and killed Newcastle disease vaccines (LaSota strain) in broiler chicks

2012 ◽  
Vol 26 (Suppl. III) ◽  
pp. 257-261
Author(s):  
A.A. Shamaun ◽  
A.A.A. Al-Hialli
2016 ◽  
Vol 47 (3) ◽  
Author(s):  
ABDULWAHID & et al.

This study was aimed to enhance the immune response of the broilers by vitamin E and Cod liver oil supplement with locally inactivated bivalent vaccine of Newcastle disease and Infectious bronchitis viruses. One hundred and twenty broiler chicks Ross 308 were divided to four groups at 30 chicks of each group. The 2nd group was vaccinated with 0.5ml/chick of locally inactivated ND-IB vaccine at 5 days old. The 3rd group was vaccinated with 0.5ml locally ND-IB vaccine and 0.1 ml/chick of VE. The 4th group was vaccinated with 0.5ml of locally ND-IB vaccine and 0.1ml/chick of Cod liver oil, while the first group was left without vaccination as a control group. All groups were vaccinated with attenuated ND-IB at 3 days old and attenuated IBD at 14 days old. The results of ELISA test revealed that the 3rd and 4th groups showed significantly increased (P≤0.05) in Ab titers against ND virus at aged 35 days, also, the 4th group showed significantly (P≤0.05) increased in Ab titers against IB virus at day 35 of age as compared with the other groups. The 4th group showed a significant (P≤0.05) increased in bursal index as compared with the other groups. The results of challenge test revealed that vaccinated groups resist the velogenic ND and IB viruses with relatively high productive range particularly the 4th group as compared with other groups. In conclusion, the VE and Cod liver oil supplement with local bivalent oil based vaccine of ND and IBV may enhance the immune response of the broilers particularly the 4th group which vaccinated with 0.5 ml of local bivalent oil based vaccine of ND-IB vaccine and 0.1 ml Cod liver oil.


2010 ◽  
Vol 7 (2) ◽  
pp. 296-302 ◽  
Author(s):  
MA Jalil ◽  
MA Samad ◽  
MT Islam

The study was conducted to determine the persistence of maternally derived antibody (MDA) and its effects on protection against NDV in broiler chickens and to investigate the status of humoral immune response following vaccination with BCRDV® (F-strain, lentogenic) at different ages of broiler chickens during the period from August to October,  2008. A total of 90 day-old broiler chicks of Cobb 500 strain with the history of vaccination of parent stock against Newcastle disease (ND) was divided into three groups (A, B and C). Birds of group A (n = 35) were used for the study of protection ability of MDA against NDV, the birds of group B (n = 45) were used for the measurement of humoral immune response in chickens following vaccination at different ages and birds of group C (n = 10) were used for the determination of persistence of maternally derived antibody. The level of antibody titre against NDV was determined by HI test. The protective potentiality of MDA and vaccine was determined by the rate of survivability of the chickens following challenge infection. It was observed that the MDA titre in day-old chicks was higher and gradually declined at minimal level at day 28. The MDA titre of 128 or above protected the birds following challenge infection with virulent NDV. There were significant decrease in HI titres of chickens which were vaccinated once at day 1 and day 7, and could not withstand challenge infection with virulent NDV. Single vaccination with BCRDV® at day 14 triggered the production of antibody but could not provide complete protection to the birds. The birds which were boosted with the same vaccine 7 days and 21 days after primary vaccination produced better immune response. However, the birds which were vaccinated primarily at day 1 and boosted at day 7 could not withstand the challenge completely. Of the other regimens of twice vaccination, primary vaccination at day 7 and booster dosing at day 28 was found to be the best in terms of immune response and protection potentiality. Therefore, it may be concluded that (a) The MDA titre level of 128 or above is sufficient to protect broilers against challenge with virulent NDV,( b) Primary vaccination at day 7 followed by a booster dosing at day 28 may be followed for better immune response and protection against ND in broilers.DOI: 10.3329/bjvm.v7i2.5995Bangl. J. Vet. Med. (2009). 7(2) : 296 – 302


2008 ◽  
Vol 11 (14) ◽  
pp. 1848-1851 ◽  
Author(s):  
R.A. Jafari ◽  
M. Razi Jalali ◽  
M. Ghorbanpoo ◽  
S.M.R. Marashian Saraei

2020 ◽  
Vol 64 (2) ◽  
pp. 74-79
Author(s):  
K. G. Madubuike ◽  
O. N. Okoroafor ◽  
I. U. Asuzu

AbstractThe administration of antibiotics to day old chicks as a means of prevention or treatment of suspected hatchery or farm-borne infections is common, especially in developing countries. This practice could contribute to a poor immune response following Newcastle disease (ND)-LaSota vaccinations, in addition to the sluggish growth in broiler chickens. This study was aimed at determining: the antibody titre to ND-LaSota vaccine, live weight, weight gain and feed conversion efficiency (FCE) of broiler chicken exposed early to gentamicin and doxycycline. One hundred, day-old broiler chicks were randomly assigned to four groups (n = 25). Group 1 served as a control, while groups 2 and 4 received gentamycin and doxycycline, respectively. The chicks in group 3 were treated with a combination of gentamicin and doxycycline (1 : 1). All drugs were administered via the drinking water from the 2nd to the 6th day of the chicks’ life. On day 18, the birds received ND-LaSota vaccine intraocularly. At weekly intervals, the post-vaccination antibody titre, live weight and weight gain were determined. The feed conversion efficiency (FCE) of the different groups was calculated at the end of the experiments. The results showed that the NDV antibody titre of the antibiotic-treated groups did not differ significantly (P < 0.05) from that of the control. However, there was a significant (P < 0.05) increase in the live weight, weight gain and FCE of the control birds when compared to the antibiotic-treated groups.


2021 ◽  
Vol 44 (3) ◽  
pp. 38-42
Author(s):  
O. O. Oni ◽  
K. O. Bello ◽  
O. F. Soyinka

Newcastle disease (ND) remains one of the major diseases ravaging the poultry industry in Nigeria. Vaccination of birds is carried out to protect birds against the disease. Despite vaccination against ND, birds still come down with the disease. This study was conducted to determine the potency of ND vaccines sold at different veterinary outlets in Abeokuta. Newcastle disease vaccines were purchased from three veterinary outlets (I, II and III) in Abeokuta over a period of 3 weeks and the haemagglutination (HA) titre determined. A total of 50 broiler chicks were also purchased and divided into 4 groups A-D. Groups A-C had 12 birds each and vaccinated against ND while Group D (Control) had 14 birds and were not vaccinated against ND. Groups A-C were vaccinated with ND vaccines with different HA titre and the antibody response determined using haemagglutination inhibition (HI) assay. Varying haemagglutination titre was recorded for all the vaccines purchased from the three outlets. The first batch of vaccines had haemagglutination titre of 0log2, 6log2 and 0log2 for outlets A, B and C respectively. The second batch had 6log2, 7log2 and 5log2 while the third batch had 4log2, 3log2 and 3log2 for outlets A, B and C respectively. Antibody titre stimulated in vaccinated birds by the second batch of vaccines for groups A, B and C birds were 1536log2, 1792log2 and 768log2 respectively, while the control birds had HI titre of 5log2. It is recommended that veterinary outlets improve the storage of vaccines, vaccine potency test be carried out on vaccines regularly and seromonitoring for humoral immune response in vaccinated chicken flocks be carried out for successful control of Newcastle disease.


2014 ◽  
Vol 3 (1) ◽  
pp. 150-157
Author(s):  
Khalid M. Gaafar

The research was conducted to study the effect of feeding broiler chickens on diets containing isomaltooligosaccharides on the growth performance, carcass traits and immune response. 90-one day old broiler chicks were used according to completely randomized two treatment groups and one control, 30 birds each. Birds fed ad-libitum on basal starter and grower-finisher diets for 35 day. Diets of treatment`s groups contained 0.5 g/Kg and 1 g/Kg of Isomaltooligosaccharides, while the control group fed on the basal diets without Isomaltooligosaccharides supplementation. Dietary supplementation of broiler chickens with Isomaltooligosaccharides improved body weight, feed conversion, carcass traits, two lymphoid organs weight and log antibody titer against avian flu vaccine. Most of the highest values were for birds fed low levels of Isomaltooligosaccharides. Feed intake decreases as Isomaltooligosaccharides level increases. Dietary supplementation with Isomaltooligosaccharides did not affect the lipids profile (triglycerides, total cholesterol, LDL and HDL), however the blood VLDL levels decreased with increased levels of Malondialdehyde and Glutathione reductase. Collectively, Dietary supplementation of broiler chickens with 0.5 g/Kg diet of Isomaltooligosaccharides improved growth performance, carcass traits and immune status.


2021 ◽  
pp. 1-8
Author(s):  
Hanan A. Hassan ◽  
A. R. Arafat ◽  
K. Y. Farroh ◽  
M. S. Bahnas ◽  
I. El-wardany ◽  
...  

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