scholarly journals Effects of Sedation with Medetomidine and Dexmedetomidine on Doppler Measurements of Ovarian Artery Blood Flow in Bitches

Animals ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 538
Author(s):  
Paloma Nicolás-Barceló ◽  
Martina Facchin ◽  
Fernando Martínez-Taboada ◽  
Rafael Barrera ◽  
José Ignacio Cristóbal ◽  
...  
Keyword(s):  
Blood Flow ◽  
Flow Velocity ◽  
Drug Administration ◽  
Peak Systolic Velocity ◽  
Resistive Index ◽  
Good Choice ◽  
Excessive Bleeding ◽  
Ovarian Artery ◽  
Arterial Blood ◽  
Diastolic Velocity

The aim was to evaluate if medetomidine and dexmedetomidine affected arterial ovarian blood flow in dogs. The dogs were randomly assigned to two different groups. In Group 1, medetomidine (10 µg/kg) was administered intramuscularly and, in Group 2, dexmedetomidine (5 µg/kg) was used. After a preliminary exam, arterial blood pressure (BP) was measured and a duplex Doppler ultrasonographic examination of both ovarian arteries was performed. Twenty minutes after the administration of medetomidine or dexmedetomidine, BP and ovarian Doppler ultrasonography were repeated. High quality tracings of ovarian artery flow velocity were obtained in all dogs and Doppler parameters: Peak Systolic Velocity (PSV), End Diastolic Velocity (EDV) and Resistive Index (RI) were measured before and after drug administration in the left (LO) and right (RO) ovaries. PSV and EDV values decreased significantly after drug administration (p < 0.05) compared to the non-sedated values, but no differences were found between the LO and RO (p > 0.05). The RI was not affected by drugs administration in neither of the groups studied (p > 0.05). In conclusion, the administration of medetomidine or dexmedetomidine causes a decrease in blood flow velocity in the ovarian artery and may be a good choice to avoid excessive bleeding prior surgeries in which ovariectomy.

Influence of Smoking Cigarettes on Cerebral Blood Flow Parameters

2013 ◽  
Vol 17 (1) ◽  
pp. 8-12 ◽  
Author(s):  
Jan Kochanowicz ◽  
Jolanta Lewko ◽  
Robert Rutkowski ◽  
Grzegorz Turek ◽  
Andrzej Sieskiewicz ◽  
...  
Keyword(s):  
Blood Flow ◽  
Flow Velocity ◽  
Cerebral Artery ◽  
Blood Flow Velocity ◽  
Cerebral Arteries ◽  
Velocity Ratio ◽  
Peak Systolic Velocity ◽  
Flow Parameters ◽  
Diastolic Velocity ◽  
Increased Risk

Introduction: While chronic cigarette smoking can lead to increased risk of stroke, the acute effects of smoking have not been established. We studied the changes in blood flow parameters in the major cerebral arteries caused by smoking one cigarette. Method: Using transcranial color-coded sonography (TCCS), we studied the anterior cerebral artery (ACA), middle cerebral artery (MCA), posterior cerebral artery (PCA), and the internal carotid artery (ICA) of 36 healthy male volunteers before and after they smoked one cigarette. Results: Blood flow velocity increased to a different degree in all but one of the arteries examined after participants smoked a single cigarette: The end diastolic velocity increased significantly by 7.8% in the PCA, 8% in the ACA, and 14.4% in the MCA. The peak systolic velocity increased significantly by 7.5% in the MCA. Blood flow velocity remained unchanged in the ICA only. Blood pressure and heart rate increased as did the flow velocity ratio for the MCA/ICA. The pulsatility index decreased after smoking from 0.92 ± 0.13 to 0.87 ± 0.14 in the MCA, 0.93 ± 0.15 to 0.87 ± 0.13 in the ACA, and 0.95 ± 0.17 to 0.89 ± 0.16 in the PCA. Conclusions: The results suggest that the direct effect of smoking on cerebral circulation includes peripheral vasodilatation with possible constriction of the main trunk of the basal cerebral arteries.

scholarly journals Dopplerfluxometria da artéria femoral de cães adultos hígidos (Canis lupus familiaris)

2018 ◽  
Vol 46 (1) ◽  
pp. 5
Author(s):  
Ivan Felismino Charas Dos Santos ◽  
Letícia Rocha Inamassu ◽  
Sheila Canevese Rahal ◽  
Maria Jaqueline Mamprim ◽  
David José De Castro Martins ◽  
...  
Keyword(s):  
Blood Flow ◽  
Femoral Artery ◽  
Pulsatility Index ◽  
Normal Values ◽  
Peak Systolic Velocity ◽  
Resistive Index ◽  
Resistivity Index ◽  
Diastolic Velocity ◽  
Healthy Dogs ◽  
The Right

Background: In Veterinary Medicine, there are several methods for early and accurate assessment of blood flow dynamics. The Dopplerfluxometry can access the peak systolic velocity, mean velocity and end diastolic velocity, including Resistive Index and Pulsatility Index. Normal values of Dopplerfluxometry in healthy dogs allow the identification of vascular abnormalities and authors’ knowledge there are no reference regarding the values of Dopplerfluxometry of the femoral artery in healthy dogs. The aim of the study was to assess the femoral Dopplerfluxometry of adult healthy dogs by Resistive Index, Pulsatility Index, systolic and diastolic velocities, and femoral artery diameter.Materials, Methods & Results: Eighteen healthy intact beagle dogs, male and female, aging from 2 to 4 years old (mean ± SD: mean 3 ± 0.8 years), weighing from 10.1-17.9 kg [22.3-39.5 lb] [mean ± SD: 14.3 ± 2.7 kg (31.5 ± 5.96 lb)] were used. The dogs underwent to physical examination, complete blood cell count, serum biochemistry examination urinalysis, and radiographs examination, muscular and cardiac evaluation. Females had to be in anestrous. All dogs were submitted to right femoral artery Dopplerfluxometry. The dogs were positioned in dorsal recumbency by one person without any chemical restraint. A high definition ultrasound device equipped with a 3 - 13 MHz multi-frequency linear transducer was used. The right femoral artery was identified with the transducer positioned transversely on the right triangle femoral area. Peak systolic velocity, end-diastolic velocity was measured. The Resistivity Index and Pulsatility Index were calculated automatically by the ultrasound machine software. Three measurements were obtained with the Doppler spectrum. The values of peak systolic velocity, end-diastolic velocity, Resistivity Index, Pulsatility Index and femoral artery diameter were expressed as Mean ± Standard Deviation (SD).Discussion: No studies regarding to femoral artery Dopplerfluxometry in healthy dogs were found in the literature. These results can be used as normal reference values of Dopplerfluxometric parameters for adult dogs. The literature cited only Dopplerfluxometric values of renal arteries, abdominal aorta and of the internal thoracic artery. The normal values of arterial Dopplerfluxometry is necessary to identify the spectral quantitative characteristics of the blood flow for diagnosis and prognosis of vascular diseases. Authors referred to changes in blood perfusion by Dopplerfluxometry examination, but no changes in B-mode ultrasonography. The femoral Resistivity Index values can be used to correlate the postoperative evolution in dogs submitted to femoral bone, hip and knee surgeries, since Dopplerfluxometry allows blood flow assessment in the femoral region muscles. Changes in the heart rate, blood pressure, stress, exercise, and diseases as hypotension, renal lesion, hepatic diseases, diabetes, hyperadrenocorticism can change the Dopplerfluxometric parameters. All dogs which used in this study were clinically healthy, and were used beagle dogs due to lowest variations within breed. Sedation was avoid due to possible changes in Dopplerfluxometric parameters since the use of sedation or tranquilization in animals is strongly discussed due to possible hemodynamic changes that may occur during the examination. In conclusion, the mean values of the right femoral artery Dopplerfluxometry in male and female adult healthy dogs is Resistivity Index (0.887); Pulsatility Index (1.599); peak systolic velocity (124.41 cm/s), end-diastolic velocity (14.12 cm/s), femoral artery diameter (3.9 mm).

scholarly journals Transcranial Doppler Sonography for Detecting Stenosis or Occlusion of Intracranial Arteries in People with Acute Ischemic Stroke in Neurocritical Care Unit.

2020 ◽  
pp. 1-17
Keyword(s):  
Blood Flow ◽  
Confidence Interval ◽  
Flow Velocity ◽  
Transcranial Doppler ◽  
Neurocritical Care ◽  
Cerebral Blood Flow Velocity ◽  
Transcranial Doppler Sonography ◽  
Peak Systolic Velocity ◽  
Mean Flow ◽  
Diastolic Velocity

Introduction: A Transcranial Doppler (TCD) is an inexpensive noninvasive ultrasonography technique that helps provide a rapid real time measure of blood flow from the basal intracerebral vessels, which may be used for the diagnosis and follow-up of cerebrovascular disease. By placing the ultrasound probe on the scalp; it utilizes low frequency soundwaves to record cerebral blood flow velocity, and its change in multiple conditions. Technology offers several diagnostic tests available in the evaluation and treatment of cerebrovascular diseases (CVD). Transcranial ultrasonography may represent a valuable tool for patients with CVD in neurocritical care unit. However due to geographic, financial or patient tolerance of procedures, physicians may be limited to the tools they can utilize. Method: Diagnostic accuracy of transcranial ultrasonography in acute stroke was subjected to systematic review. This study will set to demonstrate that the Transcranial Doppler (TCD) ultrasound is a viable piece of technology, which overcomes barriers mentioned in both the diagnosis and treatment of CVD. Cerebral flow peak systolic velocity (CBFVs), mean flow velocity (CBFVm), and the end diastolic velocity CBFVd) values are three components, which characterize the spectral waveform derived from TCD. These flow velocities provide valuable physiologic perspectives in various intracranial pathologies. We have demonstrated TCD to be highly predictive of evidence of vasospasm in patients with an aneurysmal subarachnoid hemorrhage with a 95% confidence interval. In patients with traumatic brain injury, TCD has been shown to be effective with a 95% confidence interval in the assessment of intracranial pressure and cerebral flow velocity. For strokes, TCD was shown to be effective with an overall sensitivity of 83% for the diagnosis, prognosis and treatment of ischemic strokes. Results: Due to its portability, affordability, and noninvasive application along with the high confidence intervals seen in our study, our data suggests the successful application of TCD in various pathologies in both diagnosis and monitoring of patients with various CVD.

scholarly journals Racial differences in the correlations between structural parameters and ocular blood flow in healthy eyes

2018 ◽  
Vol 2 (1) ◽  
pp. 29-41
Author(s):  
Koosha Ramezani ◽  
Alon Harris ◽  
Brent Siesky ◽  
Carine Olinde ◽  
Darrell WuDunn ◽  
...  
Keyword(s):  
Blood Flow ◽  
Racial Differences ◽  
Structural Parameters ◽  
Peak Systolic Velocity ◽  
Resistive Index ◽  
Ocular Blood Flow ◽  
Rnfl Thickness ◽  
Diastolic Velocity ◽  
The Relationship ◽  
Healthy Eyes

Purpose: This study aimed to assess differences in the relationship between structural parameters and ocular blood flow between persons of African (AD) and European descent (ED) with healthy eyes.Methods: The relationship between structural and ocular blood flow parameters was assessed in 46 participants (20 AD, 26 ED) with healthy eyes. Disc area (DA), rim area (RA), and retinal nerve fiber layer (RNFL) thickness were measured. Retrobulbar blood flow was assessed in the ophthalmic (OA), central retinal (CRA), nasal (NPCA) and temporal short posterior ciliary arteries (TPCA). Peak systolic velocity (PSV), end diastolic velocity (EDV) and resistive index (RI) were assessed. Retinal capillary blood flow was also evaluated. Differences between the correlations were determined using the Fisher r-to-z transformation.Results: Significant differences in correlations were observed between the AD and ED groups in the CRA, where PSV and DA were positively correlated in AD (r=0.43) and negatively correlated in ED (r=-0.36) (Δr=0.79; P=0.01). A similar finding was observed for PSV and RA (AD: r=0.39; ED: r=-0.23; Δr=0.62; P=0.04). In the inferior hemifield for ED group only, percentage of avascular space and RNFL thickness were positively correlated (r=0.51, P=0.01) and mean retinal flow and RNFL thickness were negatively correlated (r=-0.50, P=0.01).Conclusion: The relationship between structural parameters and the blood supply to the superficial layer of the retina was significantly different in the healthy eyes of AD compared to ED. More research is required to show how these differences may affect glaucomatous risk.

scholarly journals Gambaran Priapism pada USG Doppler

2016 ◽  
Vol 1 (4) ◽  
pp. 256-259
Author(s):  
Indri Haryuni ◽  
Sudarmanta Sudarmanta
Keyword(s):  
Doppler Ultrasound ◽  
Penile Erection ◽  
Peak Systolic Velocity ◽  
Resistive Index ◽  
Duplex Sonography ◽  
Adequate Treatment ◽  
Non Invasive ◽  
Arterial Blood ◽  
Diastolic Velocity ◽  
Ischemic Priapism

Priapism is a penile erection that lasts 4 hours or longer and is not associated with sexual activity. Identifcation of priapism is important because it requires treatment in time as soon as possible, especially for the low-?ow priapism/ischemic subgroups. Handling too late may lead to persisting erectile dysfunction as a result of irreversible corporal fbrosis. Therefore, the accurate radiology diagnosis is required to get adequate treatment. Penile Doppler ultrasound is the frst examination to distinguish the hemodynamic abnormalities in the penis of the in?ow and out?ow vessels.Some of the parameters used to measure penile arterial blood ?ow is peak systolic velocity (PSV), end diastolic velocity (EDV) and resistive index (RI). Among the index, PSV is the most frequently used parameters. Priapism is classifed into ischemic and non-ischemic. At low ?ow ischemic priapism, venous out?ow is not visible on cavernosography and pulsation was not palpable. In ischemic priapism, Doppler ultrasound is useful for the identifcation of arterial ?ow cavernosal (no ?ow is suspected as cavernosal infarction), identifcation of variants of ischemic priapism that there is still high ?ow (often > 1-2 m/s) with high resistance (i.e non-perfusing). At low ?ow priapism there is a stasis of blood in the corpora cavernosa resulting in low pO2 and higher pCO2. The pH of the corporeal blood drops below 7.0 (acidosis). Erection then becomes painful and may progress to irreversible corporal fbrosis. Pain arising from tissue hypoxia and acidosis. It required immediate intervention therapy with irrigation and aspiration of corporal blood of150 - 200 ml. On color-?ow duplex sonography, non-ischemic high-?ow priapism shows high arterial in?ow and venous out?ow cavernosography showed normal. pH rises above 7.0. Color-?ow duplex sonography is a non-invasive examination compared to cavernosography.

Diurnal variation in time to presyncope and associated circulatory changes during a controlled orthostatic challenge

2010 ◽  
Vol 299 (1) ◽  
pp. R55-R61 ◽  
Author(s):  
N. C. S. Lewis ◽  
G. Atkinson ◽  
S. J. E. Lucas ◽  
E. J. M. Grant ◽  
H. Jones ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Diurnal Variation ◽  
Flow Velocity ◽  
Blood Flow Velocity ◽  
Cerebral Blood Flow Velocity ◽  
Orthostatic Challenge ◽  
Arterial Blood ◽  
Neurally Mediated Syncope

Epidemiological data indicate that the risk of neurally mediated syncope is substantially higher in the morning. Syncope is precipitated by cerebral hypoperfusion, yet no chronobiological experiment has been undertaken to examine whether the major circulatory factors, which influence perfusion, show diurnal variation during a controlled orthostatic challenge. Therefore, we examined the diurnal variation in orthostatic tolerance and circulatory function measured at baseline and at presyncope. In a repeated-measures experiment, conducted at 0600 and 1600, 17 normotensive volunteers, aged 26 ± 4 yr (mean ± SD), rested supine at baseline and then underwent a 60° head-up tilt with 5-min incremental stages of lower body negative pressure until standardized symptoms of presyncope were apparent. Pretest hydration status was similar at both times of day. Continuous beat-to-beat measurements of cerebral blood flow velocity, blood pressure, heart rate, stroke volume, cardiac output, and end-tidal Pco2 were obtained. At baseline, mean cerebral blood flow velocity was 9 ± 2 cm/s (15%) lower in the morning than the afternoon ( P < 0.0001). The mean time to presyncope was shorter in the morning than in the afternoon (27.2 ± 10.5 min vs. 33.1 ± 7.9 min; 95% CI: 0.4 to 11.4 min, P = 0.01). All measurements made at presyncope did not show diurnal variation ( P > 0.05), but the changes over time (from baseline to presyncope time) in arterial blood pressure, estimated peripheral vascular resistance, and α-index baroreflex sensitivity were greater during the morning tests ( P < 0.05). These data indicate that tolerance to an incremental orthostatic challenge is markedly reduced in the morning due to diurnal variations in the time-based decline in blood pressure and the initial cerebral blood flow velocity “reserve” rather than the circulatory status at eventual presyncope. Such information may be used to help identify individuals who are particularly prone to orthostatic intolerance in the morning.

Effects of umbilical arterial resistance on its arterial blood flow velocity waveforms

2001 ◽  
Vol 80 (4) ◽  
pp. 307-307
Author(s):  
Makiko Mine ◽  
Junko Nishio ◽  
Yuichiro Nakai ◽  
Motoharu Imanaka ◽  
Sachio Ogita
Keyword(s):  
Blood Flow ◽  
Flow Velocity ◽  
Blood Flow Velocity ◽  
Arterial Blood Flow ◽  
Arterial Resistance ◽  
Arterial Blood

scholarly journals Feasibility of Ultrafast Doppler technique for cranial ultrasound in neonates

2019 ◽  
Vol 21 (3) ◽  
pp. 288
Author(s):  
Hyun Gi Kim ◽  
Jang Hoon Lee
Keyword(s):  
Cerebral Artery ◽  
Anterior Cerebral Artery ◽  
Posterior Cerebral Artery ◽  
Peak Systolic Velocity ◽  
Resistive Index ◽  
Quantitative Information ◽  
Cranial Ultrasound ◽  
Doppler Us ◽  
Diastolic Velocity ◽  
Cranial Arteries

Aims: The aim of this study was to compare the performances of Ultrafast Doppler ultrasound (US) with classic Doppler US, for cranial ultrasound in neonates.Materials and methods: We measured the peak systolic velocity (PSV), end-diastolic velocity (EDV) and resistive index (RI) of the anterior cerebral artery (ACA), middle cerebral artery (MCA) and posterior cerebral artery (PCA) in neonates using both conventional and Ultrafast Doppler US and acquisition times were compared. Distal ACA branches were assessed with Ultrafast Doppler US.Results: A total of 138 neonates were included. The PSV and EDV of the cranial arteries were comparable between the two Doppler methods (PSV, 64.6-85.5 cm/s vs. 63.4-84.1 cm/s, p=0.100-0.510; EDV, 19.1-26.5 cm/s vs. 17.8-24.2 cm/s, p=0.100-0.981). The RIs of the ACA and PCA were not significantly different (0.69-0.73 vs 0.68-0.74, p=0.174-0.810). Ultrafast Doppler US required shorter acquisition times than conventional Doppler US (6.7 s vs. 11.0 s, p=0.003). The PSV and EDV of the distal ACA were higher than the proximal ACA (20.1-63.3 cm/s vs. 9.4-36.7, p<0.001) although the RI was similar (0.69 vs. 0.68, p=0.251).Conclusions: Ultrafast Doppler US provides comparable values to conventional Doppler US with shorter acquisition times. This novel imaging technique provides quantitative information and is suitable for distal cranial artery evaluation.

Suctioning and Cerebral Blood Flow

PEDIATRICS ◽  
1984 ◽  
Vol 73 (5) ◽  
pp. 737-737
Author(s):  
JEFFREY M. PERLMAN ◽  
JOSEPH J. VOLPE
Keyword(s):  
Blood Pressure ◽  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Intracranial Pressure ◽  
Flow Velocity ◽  
Arterial Blood Pressure ◽  
Blood Flow Velocity ◽  
Cerebral Blood Flow Velocity ◽  
Base Line ◽  
Arterial Blood

In Reply.— Marshall misread a critical piece of information in the text. His interpretation of the data would be correct, if the intracranial pressure, arterial blood pressure, and cerebral blood flow velocity changes occurred simultaneously. However, as we stated in the text (see section on "Temporal Features of Changes with Suctioning"), the intracranial pressure fell to base-line values immediately following suctioning, whereas the changes in arterial blood pressure and cerebral blood flow velocity occurred more slowly over an approximately two-minute period.

Estimation of haemodynamic changes in varicocele testis and results after microsurgical sub-inguinal varicocelectomy

2021 ◽  
pp. 039156032110690
Author(s):  
Satyadeo Sharma ◽  
Rajendra K Shimpi
Keyword(s):  
Semen Analysis ◽  
Peak Systolic Velocity ◽  
Resistive Index ◽  
Semen Parameters ◽  
Medical Institute ◽  
Sperm Density ◽  
Doppler Study ◽  
Diastolic Velocity ◽  
Before And After ◽  
Haemodynamic Changes

Introduction: Varicocele is among the most frequently encountered, surgically correctable causes of male infertility. Since varicocele is a primary abnormality of testicular vessels, a thorough understanding of haemodynamic changes in the microcirculation of varicocele testis is needed. Objectives: To estimate changes in the microcirculation of varicocele testis and correlate them with symptomatic and semen parameters changes before and after varicocelectomy. Material and methods: This prospective, observational study includes 47 patients of age group 18–40 years who underwent microsurgical varicocelectomy during June 2016 to April 2018 at a tertiary medical institute. Testicular haemodynamic was evaluated using a colour spectral doppler study (PSV-Peak systolic velocity/ESV-End diastolic velocity/RI-Resistive index/PI-Pulsatility index). Semen analysis parameters and testicular blood flow were compared with pre-operative values. Results: RI in the capsular artery of varicocele affected testis, which was 0.61 ± 0.11 (mean ± SD), significantly reduced to 0.56 ± 0.09 (mean ± SD) in post-operative follow-up, indicating improved perfusion. Pre-operative sperm density was noted to be 15.94 ± 7.88 (mean ± SD), which improved to 28.41 ± 10.99, Progressive sperm motility from 33.81 ± 10.88 to 38.32 ± 9.21 and morphology from 36.13 ± 10.68 to 41.43 ± 9.29 on 6-month follow-ups ( p < 0.05). Conclusion: Varicocele testis is associated with altered testicular haemodynamic, which insults spermatogenesis. Microsurgical varicocelectomy with testicular artery and lymphatic preservation leads to correction of this altered haemodynamic state and improves the testicular microcirculation.

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