scholarly journals Evaluation of the Nasolabial Angle in Orthodontic Diagnosis: A Systematic Review

2021 ◽  
Vol 11 (6) ◽  
pp. 2531
Author(s):  
Vincenzo Quinzi ◽  
Licia Coceani Paskay ◽  
Nicola D’Andrea ◽  
Arianna Albani ◽  
Annalisa Monaco ◽  
...  
Keyword(s):  
Systematic Review ◽  
Hyaluronic Acid ◽  
Class Ii ◽  
Cochrane Library ◽  
Class Iii ◽  
Palatal Expansion ◽  
Rapid Palatal Expansion ◽  
Nasolabial Angle ◽  
Registration Number ◽  
Teeth Extraction

Background: This study is a systematic literature review aiming at identifying the variation of the average nasolabial angle (NLA) in various orthodontic situations. The NLA is one of the key factors to be studied in an orthodontic diagnosis for the aesthetics of the nose and facial profile. Methods: Out of 3118 articles resulting from four search engines (PubMed, Cochrane Library, Turning Research Into Practice (TRIP) and SciELO), the final study allowed the analysis and comparison of only 26 studies. These included studies have considered the NLA in the following cases: teeth extraction, class II malocclusion, class III malocclusion, rapid palatal expansion (RPE), orthognathic surgery, and non-surgical rhinoplasty with a hyaluronic acid filler. Results: The results indicate that teeth extraction and the use of hyaluronic acid fillers significantly affect the NLA. Conclusions: This systematic review shows that a statistically significant change in NLA values occurs in: extractive treatments of all four of the first or second premolars in class I patients; in class II patients with upper maxillary protrusion; in patients with maxillary biprotrusion, except for cases of severe crowding; and in patients undergoing non-surgical rhinoplasty with a hyaluronic acid filler. Trial registration number: PROSPERO CRD42020185166

scholarly journals Efficacy of Miniscrew-Assisted Rapid Palatal Expansion (MARPE) in late adolescents and adults: a systematic review and meta-analysis

2021 ◽  
Author(s):  
Aldin Kapetanović ◽  
Christina I Theodorou ◽  
Stefaan J Bergé ◽  
Jan G J H Schols ◽  
Tong Xi
Keyword(s):  
Systematic Review ◽  
Success Rate ◽  
Observational Studies ◽  
Risk Of Bias ◽  
Late Adolescents ◽  
Maxillary Expansion ◽  
Palatal Expansion ◽  
Rapid Palatal Expansion ◽  
Adolescents And Adults ◽  
Maxillary Deficiency

Summary Background Miniscrew-Assisted Rapid Palatal Expansion (MARPE) is a non-surgical treatment for transverse maxillary deficiency. However, there is limited evidence concerning its efficacy. Objectives This systematic review aims to evaluate the efficacy of MARPE in late adolescents and adults by assessing success rate and skeletal and dental transverse maxillary expansion, as well as treatment duration, dental and periodontal side effects and soft tissue effects. Search methods Seven electronic databases were searched (MEDLINE, Embase, Cochrane Library, Web of Science, Scopus, ProQuest and ClinicalTrials.gov) without limitations in November 2020. Selection criteria Randomized and non-randomized clinical trials and observational studies on patients from the age of 16 onwards with transverse maxillary deficiency who were treated with MARPE and which included any of the predefined outcomes. Data collection and analysis Inclusion eligibility screening, data extraction and risk of bias assessment were performed independently in duplicate. When possible, exploratory meta-analyses of mean differences (MDs) with their 95% confidence intervals (CIs) were conducted, followed by the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) analysis of the evidence quality. Results Eight articles were included: two prospective and six retrospective observational studies. One study had a moderate risk of bias, whereas seven studies had a serious risk of bias. GRADE quality of evidence was very low. MARPE showed a high success rate (mean: 92.5%; 95%CI: 88.7%–96.3%), resulting in a significant skeletal width increase (MD: 2.33 mm; 95%CI: 1.63 mm–3.03 mm) and dental intermolar width increase (MD: 6.55 mm; 95%CI: 5.50 mm–7.59 mm). A significant increase in dental tipping, a decrease in mean buccal bone thickness and buccal alveolar height, as well as nasal soft tissue change was present (P < 0.05). The mean duration of expansion ranged from 20 to 126 days. Limitations One of the main drawbacks was the lack of high-quality prospective studies in the literature. Conclusions and implications MARPE is a treatment modality that is associated with a high success rate in skeletal and dental maxillary expansion. MARPE can induce dental and periodontal side effects and affect peri-oral soft tissues. Given the serious risk of bias of the included studies, careful data interpretation is necessary and future research of higher quality is strongly recommended. Registration PROSPERO (CRD42020176618). Funding No grants or any other support funding were received.

scholarly journals Epidemiology of Road Traffic Accidents and Injuries in Nigeria: A Protocol for Systematic Review and Meta-analysis

2021 ◽  
Author(s):  
Samuel Osobuchi Ngene ◽  
Olatoun Adefunke Adeola ◽  
Chi-kadibia T Ukoma ◽  
Augustine Nwakuche Duru ◽  
Kayode Olaoluwa Olaniyan ◽  
...  
Keyword(s):  
Systematic Review ◽  
Standard Error ◽  
Traffic Accidents ◽  
Road Traffic ◽  
Cochrane Library ◽  
Economic Losses ◽  
Road Traffic Accidents ◽  
Road Traffic Injuries ◽  
Pooled Prevalence ◽  
Registration Number

Abstract Background: About 1.35 million people die annually worldwide due to road traffic accidents. Road traffic injuries cause considerable economic losses to individuals, their families, and to nations as a whole. About 93% of the world's fatalities on the roads occur in low-and middle-income countries, even though these countries have approximately 60% of the world's vehicles. Road Traffic Accidents constitute the third leading cause of trauma related deaths in Nigeria. It is a substantial public health problem that deserves a systematic review.Methods and Analysis: We developed a search strategy using MeSH, text words and entry terms. Nine databases will be searched, including PubMed, African Journal Online, Embase, Google Scholar, Scopus, Cochrane Library, CINAHL, Web of Science and ResearchGate. Only observational studies, retrievable in the English language will be included. The primary outcome is prevalence of road traffic injuries in Nigeria. The secondary outcomes include proportion of road traffic accidents in Nigeria, patterns, predictors and consequences of road traffic accidents in Nigeria. Identified studies will be screened and selected based on inclusion criteria using Rayyan QCRI screening tool, by independent reviewers with dual blinding. Data items will be extracted into predefined forms in Microsoft Excel before exporting to CMA version 3 for analysis. Every selected study will have their NIH quality scores and Cochrane risk of bias reported. Studies will be assessed for methodological and statistical heterogeneity. Publication bias will be assessed using Funnel Plots and test of asymmetry. Results will include forest plots, pooled prevalence with standard error, variance, relative weights assigned to studies and heterogeneity test. Further analysis will include subgroup analysis and meta-regression using both categorical and quantitative variables.Discussion: This protocol will enable a transparent, accurate and reliable method for determining pooled prevalence, standard error and 95% CI of road traffic injuries in Nigeria. Patterns and outcomes of RTA in Nigeria will also be assessed. Evidence generated by this protocol will likely inform policy on prevention of RTA in NigeriaTrial Registration Number: This protocol is registered with PROSPERO, with registration number CRD42021226956.

Skeletal and dentoalveolar effects of hybrid rapid palatal expansion and facemask treatment in growing skeletal Class III patients

2018 ◽  
Vol 153 (2) ◽  
pp. 262-268 ◽  
Author(s):  
Giuliano Maino ◽  
Ylenia Turci ◽  
Angela Arreghini ◽  
Emanuele Paoletto ◽  
Giuseppe Siciliani ◽  
...  
Keyword(s):  
Class Iii ◽  
Skeletal Class ◽  
Palatal Expansion ◽  
Rapid Palatal Expansion

Randomized Controlled Trials of Headache Treatments in Pregnancy: A Systematic Review

2020 ◽  
Author(s):  
Elisa T. Bushman ◽  
Gabriella Cozzi ◽  
Rachel G. Sinkey ◽  
Catherine H. Smith ◽  
Michael W. Varner ◽  
...  
Keyword(s):  
Systematic Review ◽  
At Risk ◽  
English Language ◽  
Statistical Significance ◽  
Cochrane Library ◽  
Control Group ◽  
Inclusion Criteria ◽  
Headache Diagnosis ◽  
Registration Number ◽  
In Pregnancy

Abstract Objective Headaches affect 88% of reproductive-aged women. Yet data are limited addressing treatment of headache in pregnancy. While many women experience improvement in pregnancy, primary and secondary headaches can develop. Consequently, pregnancy is a time when headache diagnosis can influence maternal and fetal interventions. This study was aimed to summarize existing randomized control trials (RCTs) addressing headache treatment in pregnancy. Study Design We searched PubMed, CINAHL, EMBASE, ClinicalTrials.gov, Cochrane Library, CINAHL, and SCOPUS from January 1, 1970 through June 31, 2019. Studies were eligible if they were English-language RCTs addressing treatment of headache in pregnancy. Conference abstracts and studies investigating postpartum headache were excluded. Three authors reviewed English-language RCTs addressing treatment of antepartum headache. To be included, all authors agreed each article to meet the following criteria: predefined control group, participants underwent randomization, and treatment of headache occurred in the antepartum period. If inclusion criteria were met no exclusions were made. Our systematic review registration number was CRD42019135874. Results A total of 193 studies were reviewed. Of the three that met inclusion criteria all were small, with follow-up designed to measure pain reduction and showed statistical significance. Conclusion Our systematic review of RCTs evaluating treatment of headache in pregnancy revealed only three studies. This paucity of data limits treatment, puts women at risk for worsening headache disorders, and delays diagnosis placing both the mother and fetus at risk for complications.

scholarly journals Effect of Cystic Fibrosis Transmembrane Receptor Modulators on Anthropometric and Growth Parameters in Individuals with Cystic Fibrosis: A Systematic Review (OR36-08-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Jessica Alvarez ◽  
Julianna Bailey ◽  
Ellen Bowser ◽  
Kristen Farnham ◽  
Mark Mangus, Sr. ◽  
...  
Keyword(s):  
Systematic Review ◽  
Cystic Fibrosis ◽  
Growth Parameters ◽  
Class Ii ◽  
Risk Of Bias ◽  
New Drugs ◽  
Class Iii ◽  
Qualitative Synthesis ◽  
Anthropometric Parameters ◽  
Poor Growth

Abstract Objectives Individuals with cystic fibrosis (CF) are at high risk for malnutrition and poor growth. New drugs that modulate CF transmembrane receptor (CFTR) function are available, although their effects on anthropometric parameters are not clear. This systematic review aimed to determine if various CFTR modulator therapies affect weight and growth parameters in individuals with CF. Methods A literature search was conducted using MEDLINE, CINAHL and Embase databases for peer-reviewed, randomized controlled trials (RCT) published from January 2002 to May 2018 that examined the effect of CFTR modulation therapy on weight and growth parameters in children and adults with CF. Articles were screened for relevance, data was extracted and summarized, and risk of bias was assessed to determine the quality of evidence. Results A total of 612 original articles were identified, and 13 articles representing 10 RCTs were included in qualitative synthesis and three were included in quantitative synthesis. All but one RCT demonstrated low risk of bias. The targeted class of CFTR mutation varied by RCT. Studies indicated that, in children and adults with CF with class III mutations, ivacaftor treatment alone increased weight and BMI (4 RCTs), but it did not influence growth in individuals with class II (1 RCT) or class IV mutations (1 RCT). Treatment with ivacaftor + lumacaftor in adults homozygous for the F508del CFTR mutation (class II) increased BMI following 24 weeks of treatment (2 RCTs), but there was no effect in adults heterozygous for the mutation treated for 8 weeks (1 RCT). Treatment with lumacaftor + tezacaftor in individuals ages 12–20 years with class II mutations did not change growth parameters (1 RCT). Conclusions Effects of CFTR modulators on increasing weight and growth in individuals with CF are likely dependent on the therapy formulation (single vs combination therapy) and the targeted CFTR mutation. Whereas ivacaftor alone increases weight and growth parameters in individuals with class III mutations, ivacaftor + lumacaftor is more effective at increasing BMI in adults homozygous for the class II F508del CFTR mutation. Additional studies are needed to determine effects of other CFTR modulator drugs on growth parameters in individuals with varying CFTR mutations. Funding Sources Academy of Nutrition and Dietetics/Medical Nutrition DPG, National Institutes of Health.

scholarly journals Class III Subdivision Malocclusion With Unilateral Posterior Crossbite

2015 ◽  
Vol 12 (3) ◽  
pp. 207-210
Author(s):  
R Suresh
Keyword(s):  
Medical Journal ◽  
Adolescent Girl ◽  
Class Iii ◽  
Fixed Appliance ◽  
Palatal Expansion ◽  
Posterior Crossbite ◽  
Rapid Palatal Expansion

 This article describes the management of class III subdivision malocclusion with unilateral left side posterior crossbite in an adolescent girl, using rapid palatal expansion followed by extraction of four premolars with comprehensive fixed appliance mechanotherapy.Kathmandu University Medical Journal Vol.12(3) 2014; 207-210

Surgically assisted rapid palatal expansion in class III malocclusion: Our experience

2018 ◽  
Vol 119 (5) ◽  
pp. 384-388 ◽  
Author(s):  
A. Barrabé ◽  
C. Meyer ◽  
H. Bonomi ◽  
E. Weber ◽  
N. Sigaux ◽  
...  
Keyword(s):  
Class Iii ◽  
Class Iii Malocclusion ◽  
Palatal Expansion ◽  
Rapid Palatal Expansion
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