scholarly journals A Novel Fluorescent Probe for Selective Detection of Hydrazine and Its Application in Imaging

Biosensors ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 130
Author(s):  
Ruo-Jun Man ◽  
Meng-Ke Wu ◽  
Bing Yang ◽  
Yu-Shun Yang
Keyword(s):  
Fluorescent Probe ◽  
Water Samples ◽  
High Selectivity ◽  
High Sensitivity ◽  
Living Cells ◽  
Environmental Toxicology ◽  
Future Research ◽  
Selective Detection ◽  
Anti Cancer ◽  
First Time

In this work, a novel fluorescent probe with first-time-selected thiazepine backbone, TZPzine-1, was developed for selective detection of hydrazine in water samples and living cells. Chosen from our recent anti-cancer agents, TZPzine-1 inferred structurally based advantages of the optical adjustability and the hydrazine-trapping approach. It also showed applicable properties including high sensitivity (LOD = 50 nM), wide linear range (0–15 equiv.), high selectivity (especially from competing species), rapid response (within 20 min), and practical steadiness in various pH (6.0–11.0) and temperature (15–50 °C) conditions. To satisfy the interdisciplinary requirements in environmental toxicology, TZPzine-1 was successfully applied in water samples and living cells. We hope that the information in this work, as well as the concept of monitoring the nitrogen cycle, may be referable for future research on systematic management.

Pyrene appended thymine derivative for selective turn-on fluorescence sensing of uric acid in live cells

RSC Advances ◽  
2016 ◽  
Vol 6 (71) ◽  
pp. 66774-66778 ◽  
Author(s):  
Prithidipa Sahoo ◽  
Himadri Sekhar Sarkar ◽  
Sujoy Das ◽  
Kalipada Maiti ◽  
Md Raihan Uddin ◽  
...  
Keyword(s):  
Uric Acid ◽  
Fluorescent Probe ◽  
High Sensitivity ◽  
Living Cells ◽  
Live Cells ◽  
Fluorescence Sensing ◽  
Turn On ◽  
Sensitivity And Selectivity ◽  
First Time

A new ‘turn-ON’ fluorescent probe, pyrene appended thymine acetamide (PTA), with high sensitivity and selectivity for the detection of uric acid (UA) was developed and first time imaging of uric acid in living cells in water was achieved.

A novel FRET-based fluorescent probe for the selective detection of hydrogen sulfide (H2S) and its application for bioimaging

2018 ◽  
Vol 6 (30) ◽  
pp. 4903-4908 ◽  
Author(s):  
Qi Zhao ◽  
Fangjun Huo ◽  
Jin Kang ◽  
Yongbin Zhang ◽  
Caixia Yin
Keyword(s):  
Hydrogen Sulfide ◽  
Detection Limit ◽  
Fluorescent Probe ◽  
Nude Mice ◽  
High Sensitivity ◽  
Fast Response ◽  
Living Cells ◽  
Selective Detection ◽  
Low Detection Limit ◽  
Sensitivity And Selectivity

Herein, our group developed a fast response fluorescent probe (Flu-N3) for H2S on the basis of the 7-amino-4-methylcoumarin and fluorescein FRET system with high sensitivity and selectivity and a low detection limit of 0.031 μM. Moreover, the probe was successfully applied to image exogenous and endogenous H2S in living cells and nude mice.

A mitochondria-targeted fluorescent probe based on coumarin–pyridine derivatives for hypochlorite imaging in living cells and zebrafish

2019 ◽  
Vol 7 (46) ◽  
pp. 7332-7337 ◽  
Author(s):  
Xiuli Zhong ◽  
Qing Yang ◽  
Yingshuang Chen ◽  
Yuliang Jiang ◽  
Bingxiang Wang ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
High Selectivity ◽  
A549 Cells ◽  
High Sensitivity ◽  
Living Cells ◽  
Pyridine Derivative ◽  
Pyridine Derivatives ◽  
Channel Detection ◽  
Dual Channel ◽  
Stokes Shifts

Herein, a novel coumarin–pyridine derivative (CPD) was prepared and exhibited a rapid response, large Stokes shifts, dual channel detection, high selectivity and high sensitivity toward OCl− in mitochondria of A549 cells and zebrafish.

A highly selective and sensitive photoinduced electron transfer (PET) based HOCl fluorescent probe in water and its endogenous imaging in living cells

2016 ◽  
Vol 52 (51) ◽  
pp. 7982-7985 ◽  
Author(s):  
Lijuan Liang ◽  
Chang Liu ◽  
Xiaojie Jiao ◽  
Liancheng Zhao ◽  
Xianshun Zeng
Keyword(s):  
Electron Transfer ◽  
Acridine Orange ◽  
Fluorescent Probe ◽  
Photoinduced Electron Transfer ◽  
Living Cells ◽  
Selective Detection

A probe based on the phenothiazine–acridine orange conjugate (Ptz–AO) has been designed and synthesized for the sensitive and selective detection of HOCl.

Colorimetric and Fluorescent Probe for Hypochlorite with High Selectivity

2013 ◽  
Vol 295-298 ◽  
pp. 475-478 ◽  
Author(s):  
Zhi Xiang Han ◽  
Ming Hui Du ◽  
Guo Xi Liang ◽  
Xiang Yang Wu
Keyword(s):  
Reactive Oxygen Species ◽  
Aqueous Solution ◽  
Detection Limit ◽  
Fluorescent Probe ◽  
Rhodamine B ◽  
High Selectivity ◽  
Reactive Oxygen ◽  
Living Cells ◽  
Oxygen Species ◽  
Turn On

Rhodamine B thiohydrazide (RBS) was firstly employed as turn-on fluorescent probe for hypochlorite in aqueous solution and living cells. It exhibits a stable response to hypochlorite from 1.0×10-6to 1.0×10-5M with a detection limit of 3.3×10-7M. The response of this probe to hypochlorite is fast and highly selective compared with other reactive oxygen species (such as.OH,1O2, H2O2) and other common anions (such as X-, ClO2-, ClO4-, NO3-, NO2-, OH-, Ac-, CO32-, SO42-).

A ratiometric fluorescence sensor for HOCl based on a FRET platform and application in living cells

RSC Advances ◽  
2016 ◽  
Vol 6 (21) ◽  
pp. 17059-17063 ◽  
Author(s):  
Yan-Ru Zhang ◽  
Zhi-Min Zhao ◽  
Le Su ◽  
Jun-Ying Miao ◽  
Bao-Xiang Zhao
Keyword(s):  
Fluorescent Probe ◽  
High Selectivity ◽  
Fast Response ◽  
Living Cells ◽  
Fluorescence Sensor ◽  
Ratiometric Fluorescence ◽  
Ratiometric Fluorescent Probe

A ratiometric fluorescent probe CRSH based on a FRET platform for detecting HOCl. CRSH showed high selectivity, excellent sensitivity and a fast response toward HOCl.

A pH-sensitive multifunctional fluorescent probe based on N-annulated perylene for the sensitive and selective detection of hypochlorous acid

2017 ◽  
Vol 1 (11) ◽  
pp. 2292-2298 ◽  
Author(s):  
Xiao Zhang ◽  
Yongchao Yan ◽  
Qing Peng ◽  
Jian Wang ◽  
Yandi Hang ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Water Samples ◽  
Hypochlorous Acid ◽  
Ph Sensitive ◽  
Selective Detection

The pH-sensitive multifunctional fluorescent probe PNPM based on N-annulated perylene was firstly developed for detecting HOCl selectively. And the probe could detect pH and HOCl simultaneously, and was successfully employed to detect HOCl in serum and water samples.

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