Tannic Acid-Capped Gold Nanoparticles as a Novel Nanozyme for Colorimetric Determination of Pb2+ Ions

In this study, tannic acid-modified gold nanoparticles were found to have superior nanozyme activity and catalyze the oxidation reaction of 3,3′,5,5′-tetramethylbenzidine in the presence of hydrogen peroxide. Enhancing the catalytic activity of the nanozyme by Pb2+ ions caused by selectively binding metal ions by the tannic acid-capped surface of gold nanoparticles makes them an ideal colorimetric probe for Pb2+. The parameters of the reaction, including pH, incubation time, and concentration of components, were optimized to reach maximal sensitivity of Pb2+ detection. The absorption change is directly proportional to the Pb2+ concentration and allows the determination of Pb2+ ions within 10 min. The colorimetric sensor is characterized by a wide linear range from 25 to 500 ng×mL−1 with a low limit of detection of 11.3 ng×mL−1. The highly sensitive and selective Pb2+ detection in tap, drinking, and spring water revealed the feasibility and applicability of the developed colorimetric sensor.

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Highly sensitive colorimetric determination of amoxicillin in pharmaceutical formulations based on induced aggregation of gold nanoparticles

Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy ◽

10.1016/j.saa.2015.01.071 ◽

2015 ◽

Vol 143 ◽

pp. 223-229 ◽

Cited By ~ 21

Author(s):

Morteza Akhond ◽

Ghodratollah Absalan ◽

Hamid Ershadifar

Keyword(s):

Gold Nanoparticles ◽

Pharmaceutical Formulations ◽

Colorimetric Determination ◽

Highly Sensitive ◽

Induced Aggregation

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Colorimetric copper(ii) ion sensor based on the conformational change of peptide immobilized onto the surface of gold nanoparticles

Analytical Methods ◽

10.1039/c3ay42211a ◽

2014 ◽

Vol 6 (8) ◽

pp. 2580-2585 ◽

Cited By ~ 31

Author(s):

Hongxia Chen ◽

Jiangjiang Zhang ◽

Xinjian Liu ◽

Yanmin Gao ◽

Zonghuang Ye ◽

...

Keyword(s):

Gold Nanoparticles ◽

Conformational Change ◽

Conformational Changes ◽

Colorimetric Sensor ◽

Ion Sensor ◽

Highly Sensitive ◽

Binding Peptides ◽

Determination Of Copper

A highly sensitive and selective colorimetric sensor was developed for the determination of copper(ii) ions based on the conformational changes of Cu2+-binding peptides.

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Acetylcholinesterase inhibition-based colorimetric determination of Hg2+ using unmodified silver nanoparticles

New Journal of Chemistry ◽

10.1039/c4nj01722f ◽

2015 ◽

Vol 39 (2) ◽

pp. 1172-1178 ◽

Cited By ~ 9

Author(s):

Dashananda Nanda Kumar ◽

Ayyachamy Rajeshwari ◽

Sruthi Ann Alex ◽

Natarajan Chandrasekaran ◽

Amitava Mukherjee

Keyword(s):

Silver Nanoparticles ◽

Indirect Method ◽

Colorimetric Sensor ◽

Acetylcholinesterase Inhibition ◽

Colorimetric Determination ◽

Highly Sensitive

A highly sensitive colorimetric sensor for Hg2+ was developed with unmodified AgNPs using an enzyme-based indirect method.

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Highly sensitive colorimetric determination of malathion using gold nanoparticles

Water Science & Technology Water Supply ◽

10.2166/ws.2016.029 ◽

2016 ◽

Vol 16 (5) ◽

pp. 1214-1220 ◽

Cited By ~ 5

Author(s):

Tayebeh Kohzadi ◽

Mahmoud Roushani

Keyword(s):

Gold Nanoparticles ◽

High Sensitivity ◽

Colorimetric Determination ◽

Good Precision ◽

Buffer Solution ◽

Microscopy Technique ◽

Resonance Band ◽

Highly Sensitive ◽

Agriculture Products

A highly sensitive method is presented for the colorimetric determination of malathion using gold nanoparticles (AuNPs). In this approach, the synthesized AuNPs solution was stabilized by the citrate anions as their repulsion protected the AuNPs from aggregation. The synthesized AuNPs were characterized morphologically by using transmission electron microscopy technique. Malathion caps the surface of AuNPs and induces the aggregation of AuNPs in Britton–Robinson buffer solution. The reaction was monitored spectrophotometrically by measuring the decrease in the plasmon resonance band of the AuNPs at 527 nm after 9 min. The effect of reaction variables on the reaction sensitivity was investigated and furthermore, the interference of common ions was effectively avoided. The calibration curve is linear over the concentration range 3.3 × 10−7 to 3.3 × 10−6 mol/L of malathion with good precision and accuracy and the detection limit was down to 1.5 × 10−7 mol/L. The developed approach does not use complex and expensive instruments. The high sensitivity of the proposed method allowed its successful application to wheat and water samples. Thus, the proposed strategy can serve as a powerful method for the rapid diagnosis of malathion in agriculture products.

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Low-Cost Synthesis of Gold Nanoparticles from Reused Traditional Gold Leaf and its Application for Sensitive and Selective Colorimetric Sensing of Creatinine in Urine

Current Analytical Chemistry ◽

10.2174/1573411014666181010130631 ◽

2020 ◽

Vol 16 (3) ◽

pp. 287-297

Author(s):

Arjnarong Mathaweesansurn ◽

Nathawut Choengchan ◽

Putthiporn Khongkaew ◽

Chutima M. Phechkrajang

Keyword(s):

Gold Nanoparticles ◽

Limit Of Detection ◽

Low Cost ◽

Poly Vinyl Alcohol ◽

Colorimetric Determination ◽

Au Nps ◽

Urinary Creatinine ◽

Gold Leaf ◽

Colorimetric Response

Background: Gold nanoparticles (Au NPs) are normally prepared using standard gold (III) trichloride which is much expensive and irritant. This work is aimed at demonstrating simple and low-cost synthesis of Au NPs from the reused traditional gold leaf which is cost-free and less toxic. Methods: The reused gold leaf was donated by the local temple. It was digested and used as the precursor for the preparation of the Au NPs by Turkevich method. Poly (vinyl alcohol) (PVA) was employed as a stabilizer. The as-prepared Au NPs were applied for the colorimetric determination of creatinine in urine without any sample pretreatment. Results: Long-term stability of the gold colloids was achieved for at least 3 months. Morphology and purity of the as-prepared Au NPs were the same as the ones prepared from standard gold (III) salt and standard gold foil. Colorimetric response of the Au NPs was linear to the standard creatinine up to 200 mg L-1. The limit of detection (0.16 mg L-1 or 1.41 μM) was enough sensitive for urinary creatinine detection in patients with kidney disease. Good recoveries (97-108%) and fast analysis time (3 min) were achieved. The developed method was successfully validated against the HPLC method. Conclusion: Facile and cost-effective synthesis of the Au NPs from the reused traditional gold leaf, was accomplished. The as-prepared Au NPs were successfully applied for the determination of urinary creatinine with high sensitivity and selectivity.

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Indirect Determination of Amikacin by Gold Nanoparticles as Redox Probe

Current Drug Delivery ◽

10.2174/1567201817666200719005919 ◽

2020 ◽

Vol 17 ◽

Author(s):

Mansureh Alizadeh ◽

Mandana Amiri ◽

Abolfazl Bezaatpour

Keyword(s):

Gold Nanoparticles ◽

Bacterial Infections ◽

Limit Of Detection ◽

Pharmaceutical Preparation ◽

Cathodic Peak ◽

Easy Method ◽

Peak Current ◽

Indirect Determination ◽

Tract Infections

: Amikacin is an aminoglycoside antibiotic used for many gram-negative bacterial infections like infections in the urinary tract, infections in brain, lungs and abdomen. Electrochemical determination of amikacin is a challenge in electroanalysis because it shows no voltammetric peak at the surface of bare electrodes. In this approach, a very simple and easy method for indirect voltammetric determination of amikacin presented in real samples. Gold nanoparticles were electrodeposited at the surface of glassy carbon electrode in constant potential. The effect of several parameters such as time and potential of deposition, pH and scan rates on signal were studied. The cathodic peak current of Au3+ decreased with increasing amikacin concentration. Quantitative analysis of amikacin was performed using differential pulse voltammetry by following cathodic peak current of gold ions. Two dynamic linear ranges of 1.0 × 10−8–1.0 × 10-7 M and 5.0 × 10−7–1.0 × 10-3 M were obtained and limit of detection was estimated 3.0× 10−9 M. The method was successfully determined amikacin in pharmaceutical preparation and human serum. The effect of several interference in determination of amikacin was also studied.

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