scholarly journals Retinol Has a Skin Dehydrating Effect That Can Be Improved by a Mixture of Water-Soluble Polysaccharides

Cosmetics ◽  
2020 ◽  
Vol 7 (4) ◽  
pp. 80
Author(s):  
James V. Gruber ◽  
Venera Stojkoska ◽  
Jed Riemer
Keyword(s):  
Topical Application ◽  
Untreated Control ◽  
Skin Testing ◽  
Water Soluble ◽  
Skin Hydration ◽  
Short Term ◽  
Study Methods ◽  
Barrier Disruption ◽  
Skin Erythema ◽  
Volar Forearm

It is common that retinoids used in skincare can cause skin dryness, irritation and redness which is a complaint for the use of these molecules in skincare formulations. Objective: to investigate the influence of a mixture of polysaccharides to improve retinol-based formulations in a 12-day inner volar forearm study. Methods: in total, 22 inner volar forearms were treated over a 12-day topical application of a Placebo formulation containing 0.5% retinol verses a formulation containing 0.5% retinol and 3.0% of a complex of polysaccharides. Application occurred 2X/day in the morning and evening. Skin testing included barrier disruption, erythema, and skin hydration. After a 3-day regression of treatment, skin hydration was measured again. Results: the 0.5% retinol Placebo formulation showed a significant impact on skin dehydration compared to untreated control or polysaccharide-treated areas. The formulation containing retinol and 3.0% of the polysaccharides, maintained skin hydration levels comparable to the untreated control. Neither formulation had a statistically significant impact on skin erythema or barrier disruption. After the 3-day regression, the polysaccharide mixture continued to demonstrate significant moisturization benefits superior to the untreated and active-treated sites. Conclusions: a mixture of polysaccharides was able to mitigate the short-term skin drying effects of retinol and continued to moisturize the skin after a 3-Day regression.

Topical application of a novel, water-soluble γ-tocopherol derivative prevents UV-induced skin damage in mice

2005 ◽  
Author(s):  
Shingo Yasuoka ◽  
Jiro Takata ◽  
Yoshiharu Karube ◽  
Eiko Katoh ◽  
Toshi Tsuzuki ◽  
...  
Keyword(s):  
Topical Application ◽  
Water Soluble ◽  
Skin Damage

scholarly journals How big is the influence of biogenic silicon pools on short-term changes in water-soluble silicon in soils? Implications from a study of a 10-year-old soil–plant system

2017 ◽  
Vol 14 (22) ◽  
pp. 5239-5252 ◽  
Author(s):  
Daniel Puppe ◽  
Axel Höhn ◽  
Danuta Kaczorek ◽  
Manfred Wanner ◽  
Marc Wehrhan ◽  
...  
Keyword(s):  
Water Soluble ◽  
Small Scale ◽  
Testate Amoeba ◽  
Short Term ◽  
Plant Materials ◽  
Main Driver ◽  
Key Factor ◽  
Calamagrostis Epigejos ◽  
Biogenic Silicon ◽  
Future Work

Abstract. The significance of biogenic silicon (BSi) pools as a key factor for the control of Si fluxes from terrestrial to aquatic ecosystems has been recognized for decades. However, while most research has been focused on phytogenic Si pools, knowledge of other BSi pools is still limited. We hypothesized that different BSi pools influence short-term changes in the water-soluble Si fraction in soils to different extents. To test our hypothesis we took plant (Calamagrostis epigejos, Phragmites australis) and soil samples in an artificial catchment in a post-mining landscape in the state of Brandenburg, Germany. We quantified phytogenic (phytoliths), protistic (diatom frustules and testate amoeba shells) and zoogenic (sponge spicules) Si pools as well as Tiron-extractable and water-soluble Si fractions in soils at the beginning (t0) and after 10 years (t10) of ecosystem development. As expected the results of Tiron extraction showed that there are no consistent changes in the amorphous Si pool at Chicken Creek (Hühnerwasser) as early as after 10 years. In contrast to t0 we found increased water-soluble Si and BSi pools at t10; thus we concluded that BSi pools are the main driver of short-term changes in water-soluble Si. However, because total BSi represents only small proportions of water-soluble Si at t0 (< 2 %) and t10 (2.8–4.3 %) we further concluded that smaller (< 5 µm) and/or fragile phytogenic Si structures have the biggest impact on short-term changes in water-soluble Si. In this context, extracted phytoliths (> 5 µm) only amounted to about 16 % of total Si contents of plant materials of C. epigejos and P. australis at t10; thus about 84 % of small-scale and/or fragile phytogenic Si is not quantified by the used phytolith extraction method. Analyses of small-scale and fragile phytogenic Si structures are urgently needed in future work as they seem to represent the biggest and most reactive Si pool in soils. Thus they are the most important drivers of Si cycling in terrestrial biogeosystems.

PHOSPHORUS UPTAKE BY ALFALFA AS INFLUENCED BY PHOSPHATE SOURCE AND MOISTURE

1962 ◽  
Vol 42 (2) ◽  
pp. 254-265 ◽  
Author(s):  
J. D. Beaton ◽  
D. W. L. Read ◽  
W. C. Hinman
Keyword(s):  
Phosphorus Uptake ◽  
Significant Negative Correlation ◽  
P Uptake ◽  
Water Soluble ◽  
Ammonium Polyphosphate ◽  
Short Term ◽  
Treated Soil ◽  
Extractable P ◽  
Phosphate Source ◽  
Soil Fertilizer

The effect of phosphate source and soil moisture during the initial soil-fertilizer reaction period on subsequent phosphorus uptake by alfalfa was investigated in a growth chamber. Phosphate-treated soils with moisture adjusted to four different tensions were stored at approximately 18 °C. for 10 weeks. Following this storage interval phosphorus uptake by alfalfa was measured using a short-term technique.Phosphorus content and phosphorus uptake by both tops and roots increased significantly when water-soluble materials such as ammonium polyphosphate, monoammonium and monocalcium phosphate were applied. Less soluble sources, i.e., hydroxyapatite and anhydrous dicalcium phosphate, were much less effective. Calcium metaphosphate produced intermediate results.Moisture content of the soil during the reaction period did not greatly alter subsequent P uptake. The water-soluble sources of phosphorus were affected to the greatest degree.Uptake of P was significantly correlated with the amount of P extracted by NaHCO3 from the treated soils. The highest degree of correlation occurred with ammonium polyphosphate treated soil. A significant negative correlation occurred with calcium metaphosphate. With the exception of the 0.8 bar treatment, moisture tension had little influence on the correlation of P uptake with NaHCO3 extractable-P.

Short-term steam treatment of MFC gel with and without water-soluble cellulose derivative

2019 ◽  
Vol 34 (1) ◽  
pp. 10-18
Author(s):  
Salla Hiltunen ◽  
Isto Heiskanen ◽  
Kaj Backfolk
Keyword(s):  
Thermal Treatment ◽  
Water Retention ◽  
Crystallinity Index ◽  
Water Soluble ◽  
Steam Treatment ◽  
Water Retention Capacity ◽  
Shear Forces ◽  
Short Term ◽  
Retention Capacity ◽  
Jet Cooking

Abstract Microfibrillated cellulose (MFC) with and without added CMC was exposed to short-term dynamic thermal treatment using a steam jet cooker. The effects of the elevated temperature (130 °C, ∼3 bar) and shear forces on the rheology, crystallinity index, UV/VIS adsorption and water retention were measured. Jet cooking increased the viscosity and gel strength of the MFC and MFC/CMC mixture but with CMC alone a slight decrease in viscosity was observed. The water retention capacity and crystalline indices of the MFC were not greatly affected by the short-term thermal treatment and shear forces, although a slight increase in the UV/VIS absorbance was observed.

Labile water soluble components govern the short-term microbial decay of hydrochar from sewage sludge

2017 ◽  
Vol 64 (6) ◽  
pp. 873-880
Author(s):  
Marc Breulmann ◽  
Katrin Kuka ◽  
Manfred van Afferden ◽  
François Buscot ◽  
Christoph Fühner ◽  
...  
Keyword(s):  
Sewage Sludge ◽  
Water Soluble ◽  
Short Term ◽  
Soluble Components

scholarly journals SULFATION PATHWAYS: Potential benefits of a sulfated resveratrol derivative for topical application

2018 ◽  
Vol 61 (2) ◽  
pp. M27-M39 ◽  
Author(s):  
Marta Correia-da-Silva ◽  
Verónica Rocha ◽  
Cláudia Marques ◽  
Cláudia M Deus ◽  
Adriana Marques-Carvalho ◽  
...  
Keyword(s):  
Protein Content ◽  
Topical Application ◽  
In Silico ◽  
Water Solubility ◽  
Hacat Cell ◽  
Binding Free Energy ◽  
Water Soluble ◽  
Sirtuin 1 ◽  
Trypan Blue Exclusion

Resveratrol (RSV) is a polyphenolic compound with antioxidant, anti-inflammatory and anti-aging properties partly associated with sirtuin 1 (SIRT1)-activation in the skin. However, poor water solubility may limit RSV efficacy. This work aimed to clarify the interest of a new synthetic water-soluble RSV derivative (resveratrol glucoside sulfate, RSV-GS) for topical application. Resveratrol glucoside sulfate was synthesized using microwave-assisted sulfation. Cytotoxicity assays were performed with the keratinocyte HaCaT cell line, using MTT reduction, neutral red uptake, Alamar Blue/resazurin reduction, trypan blue exclusion and measurement of ATP concentration. Western blotting was used to evaluate SIRT1 protein content. Regarding SIRT1 binding, an in silico docking study was performed, using AutoDock Vina. Our results showed that the synthetic derivative RSV-GS was 1000 times more soluble in water than RSV and its non-sulfated glucoside. No relevant decrease in HaCaT cell viability was observed for concentrations up to 5 mM for RSV-GS, and up to 500 μM for resveratrol glucoside, while a significant decrease in HaCaT viability occurred from 100 μM for RSV. RSV-GS and RSV showed a similar behavior regarding protective effect against oxidative stress-induced cytotoxicity. SIRT1 protein content increased after treatment with 500 μM of RSV-GS and 100 μM of RSV. Moreover, in silico studies predicted that RSV-GS binds more stably to SIRT1 with a lower binding free energy than RSV. Although these results support the possible use of RSV-GS in topical formulations, in vivo safety and efficacy studies are needed before considering the use of RSV-GS in commercial products.

Sign in / Sign up

Export Citation Format

Share Document