scholarly journals Grip Strength: A Useful Marker for Composite Hepatic Events in Patients with Chronic Liver Diseases

Diagnostics ◽  
2020 ◽  
Vol 10 (4) ◽  
pp. 238 ◽  
Author(s):  
Kazunori Yoh ◽  
Hiroki Nishikawa ◽  
Hirayuki Enomoto ◽  
Yoshinori Iwata ◽  
Naoto Ikeda ◽  
...  
Keyword(s):  
Grip Strength ◽  
Muscle Mass ◽  
Cumulative Incidence ◽  
Liver Diseases ◽  
Short Form ◽  
Incidence Rates ◽  
Chronic Liver ◽  
Prognostic Impact ◽  
Chronic Liver Diseases

Here we sought to clarify the prognostic impact of sarcopenia-related markers (grip strength (GS), muscle mass using bioimpedance analysis and patient quality of life as assessed by the 36-Item Short-Form Health Survey (SF36)) in patients with chronic liver diseases (CLDs, n = 411; 160 liver cirrhosis patients; median age, 64 years) on the incidence of composite hepatic events (CHEs). A GS decrease was defined as <26 kg in men and <18 kg in women, while a skeletal muscle mass index (SMI) decrease was defined as <7.0 kg/m2 in men and <5.7 kg/m2 in women based on the current guidelines. The physical and metal component summary scores on the SF36 were also included into the analysis. Sixty-two patients (15.1%) had the first incidence of CHEs. The three-year cumulative incidence rates of CHEs in patients with GS decrease or non-decrease were 24.51% and 12.44% (p = 0.0057). The three-year cumulative incidence rates of CHEs in patients with an SMI decrease or non-decrease were 19.65% and 12.99% (p = 0.0982). Multivariate analysis revealed that GS decrease (p = 0.0350) and prothrombin time (p = 0.0293) were significantly associated with the incidence of CHEs. In conclusion, GS can be an independent predictor for CHE development in patients with CLDs.

scholarly journals Predictors of Quality of Life after Liver Transplant

2019 ◽  
Vol 2 (1) ◽  
Author(s):  
Joey Wu ◽  
Archita Desai, MD
Keyword(s):  
Quality Of Life ◽  
Liver Disease ◽  
General Population ◽  
Liver Transplant ◽  
Liver Diseases ◽  
Chronic Liver ◽  
University Hospital ◽  
Chronic Liver Diseases ◽  
The Impact

Background and Hypothesis: The impact of chronic liver diseases on patients and their family member is often understated and understudied. Chronic liver diseases can sometimes progress to a need for Liver transplant (LT). While recent studies have described quality of life (QOL) at different stages of liver disease, the impact of the patient’s QOL in LT survivors has not been examined. The importance of studying QOL in patients is due to its effect on the survivorship of LT recipients. We hypothesize that QOL in LT patients is lower than the general population. Our aim was to describe predictors of QOL in a well-described cohort of LT patients. Methods: Patients were enrolled at the Digestive and Liver Disease Liver clinic at Indiana University Hospital. All patients over the age of 18 were approached, if patients consented to the study, they were then enrolled during their liver follow up visit. The PROMIS survey was administered on an iPad and completed during the clinic visit. Survey were then scored and analyzed. Results: The T-scores for post liver transplant patients are lower in physical function, anxiety and depression, but higher in general life satisfaction compared to the general population. LT recipients have similar T-scores in Fatigue, Sleep disturbance, ability to participate in social activities, and pain interference compared to the general population. Conclusion and Potential Impact: Previous diagnosis of PBC, HCC, diagnosis of depression, household income, insurance status, Charlson Comorbid Index and number of non-transplant related medications have the highest association with quality of life. Further enrollment is needed to increase the power of the study. However, this can inform physicians the importance to taking these factors in to consideration in order to improve the QOL in LT recipients.

ASSESMENT OF FATIGUE IN PATIENTS WITH CHRONIC LIVER DISEASES

2021 ◽  
pp. 49-53
Author(s):  
М.D. Golubeva ◽  
◽  
К.V. Darafeyeva ◽  
D.E. Danilau ◽  
D.V. Litvinchuk ◽  
...  
Keyword(s):  
Liver Disease ◽  
Chronic Liver Disease ◽  
Liver Diseases ◽  
Short Form ◽  
Chronic Liver ◽  
Assessment Scale ◽  
Chronic Liver Diseases ◽  
Fatigue Assessment ◽  
Chronic Liver Disease Questionnaire ◽  
Disease Questionnaire

To determine the most sensitive questionnaire for the detection of fatigue in patients with chronic liver diseases, 61 patients with chronic liver diseases were inpatient treatment at the City Infectious Diseases Clinical were interviewed. And 72 relatively healthy responses were interviewed using Chronic Liver Disease Questionnaire, the Short Form-36, the Fatigue Assessment Scale. The study was conducted between November 2019 and March 2020. The severity of fatigue and declining quality of life was correlated with the presence of chronic liver diseases, excess body weight, and female sex. The Short Form-36 questionnaire showed greater sensitivity for assessing fatigue in people with chronic liver diseases compared to the Chronic Liver Disease Questionnaire. The Fatigue Assessment Scale didn't reveal reliable differences between the groups being compared.

scholarly journals PGI36 Relationship Between Clinical Severity and Health Related Quality of Life in Chronic Liver Diseases

2012 ◽  
Vol 15 (7) ◽  
pp. A332 ◽  
Author(s):  
L. Scalone ◽  
P.A. Cortesi ◽  
R. Ciampichini ◽  
S. Okolicsanyi ◽  
M. Rota ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Liver Diseases ◽  
Chronic Liver ◽  
Clinical Severity ◽  
Health Related Quality ◽  
Chronic Liver Diseases ◽  
Related Quality ◽  
Health Related

scholarly journals Decrease in grip strength is associated with the progression of sleep disturbances in chronic liver diseases

2021 ◽  
Vol 3 (2) ◽  
Author(s):  
Hiroki Nishikawa ◽  
Kazunori Yoh ◽  
Hirayuki Enomoto ◽  
Takashi Nishimura ◽  
Shuhei Nishiguchi ◽  
...  
Keyword(s):  
Grip Strength ◽  
Liver Diseases ◽  
Sleep Disturbances ◽  
Chronic Liver ◽  
Chronic Liver Diseases

scholarly journals Possibilities of echography in chronic liver diseases and portal hypertension

2001 ◽  
Vol 82 (6) ◽  
pp. 430-436
Author(s):  
R. F. Raimova ◽  
D. K. Bashirov ◽  
M. G. Tukhbatullin
Keyword(s):  
Portal Hypertension ◽  
Liver Diseases ◽  
Life Quality ◽  
The State ◽  
Chronic Liver ◽  
Surgical Correction ◽  
Chronic Liver Diseases ◽  
Adequate Therapy ◽  
Early Signs

The possibilities of the complex echography in studies of the state of patients with chronic liver diseases are estimated. It is concluded that in definite situations the complex echography has undeniable advantages because it makes it possible to reveal early signs of portal hypertension and to predict its course. This will make it possible to choose more adequate therapy and to perform timely surgical correction and to improve the life quality of patients.

scholarly journals Quality of life in patients with chronic hepatitis C

2011 ◽  
Vol 139 (3-4) ◽  
pp. 165-169
Author(s):  
Sladjana Pavic ◽  
Dragan Delic ◽  
Jasmina Simonovic ◽  
Neda Svirtlih
Keyword(s):  
Quality Of Life ◽  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Liver Diseases ◽  
Chronic Liver ◽  
Healthy Population ◽  
Chronic Liver Diseases ◽  
Chronic Hepatitis C Patients

Introduction. Hepatitis C virus often causes chronic liver disease reducing physical, mental and social functions in these patients. Objective. The aim of this investigation was analysis of the quality of life in chronic hepatitis C patients compared to patients with other chronic liver diseases and healthy population, as well as investigation of the influence of socio-demographic factors on the quality of life in patients with chronic hepatitis C. Methods. A generic Short Form-36 (SF-36) questionnaire and Chronic Liver Diseases Questionnaire (CLDQ) were used in this prospective study for the investigation of the quality of life in 160 patients (100 patients with chronic hepatitis C, 30 patients with chronic hepatitis B, 30 patients with non-viral chronic liver diseases) and 50 healthy controls. Results. Reduced quality of life was noted in patients with chronic hepatitis C patients in comparison with healthy controls (p=0.00). Significant differences in SF-36 were found between patients with chronic hepatitis C and B regarding physical functions, activity, physical pain and emotional functions. Multivariate linear regression analysis revealed ages below 50 years as the most important positive variable in chronic hepatitis C patients for total score of the quality of life and physical component score (B=14.5; SE=5.16; p=0.049; and B=16.4; SE=5.94; p=0.003, respectively). The most important positive variable for the mental component of the quality of life was male gender (B=15.3; SE=5.81; p=0.003). Conclusion. Quality of life is reduced in patients with chronic hepatitis C in comparison with healthy population. The quality of life in chronic hepatitis C patients is better than in patients with other non-viral chronic liver diseases. In comparison with patients with chronic hepatitis B, reduction in some domains of the quality of life is noted. Younger age is the most predictable group for the lowest damage of the total quality of life in patients with chronic hepatitis C patients among other socio- demographic characteristics of these patients.

scholarly journals Quality of Life of the Patients Suffering from Chronic Liver Diseases at the University Health Center Campus of Lome

2015 ◽  
Vol 05 (07) ◽  
pp. 88-93
Author(s):  
Aklesso Bagny ◽  
Oumboma Bouglouga ◽  
Late Mawuli Lawson-Ananissoh ◽  
Angelique Dusabe ◽  
Yeba Laconism Kaaga ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Health Center ◽  
Liver Diseases ◽  
Chronic Liver ◽  
Chronic Liver Diseases ◽  
The University
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