scholarly journals Whole-Body Regeneration in the Lobate Ctenophore Mnemiopsis leidyi

Genes ◽  
2021 ◽  
Vol 12 (6) ◽  
pp. 867
Author(s):  
Allison Edgar ◽  
Dorothy G. Mitchell ◽  
Mark Q. Martindale

Ctenophores (a.k.a. comb jellies) are one of the earliest branching extant metazoan phyla. Adult regenerative ability varies greatly within the group, with platyctenes undergoing both sexual and asexual reproduction by fission while others in the genus Beroe having completely lost the ability to replace missing body parts. We focus on the unique regenerative aspects of the lobate ctenophore, Mnemiopsis leidyi, which has become a popular model for its rapid wound healing and tissue replacement, optical clarity, and sequenced genome. M. leidyi’s highly mosaic, stereotyped development has been leveraged to reveal the polar coordinate system that directs whole-body regeneration as well as lineage restriction of replacement cells in various regenerating organs. Several cell signaling pathways known to function in regeneration in other animals are absent from the ctenophore’s genome. Further research will either reveal ancient principles of the regenerative process common to all animals or reveal novel solutions to the stability of cell fates and whole-body regeneration.

1998 ◽  
Vol 1 (1) ◽  
pp. 23-39
Author(s):  
Carter J. Kerk ◽  
Don B. Chaffin ◽  
W. Monroe Keyserling

The stability constraints of a two-dimensional static human force exertion capability model (2DHFEC) were evaluated with subjects of varying anthropometry and strength capabilities performing manual exertions. The biomechanical model comprehensively estimated human force exertion capability under sagittally symmetric static conditions using constraints from three classes: stability, joint muscle strength, and coefficient of friction. Experimental results showed the concept of stability must be considered with joint muscle strength capability and coefficient of friction in predicting hand force exertion capability. Information was gained concerning foot modeling parameters as they affect whole-body stability. Findings indicated that stability limits should be placed approximately 37 % the ankle joint center to the posterior-most point of the foot and 130 % the distance from the ankle joint center to the maximal medial protuberance (the ball of the foot). 2DHFEC provided improvements over existing models, especially where horizontal push/pull forces create balance concerns.


Author(s):  
C. Rajalingham ◽  
R. B. Bhat ◽  
G. D. Xistris

Abstract The natural frequencies and natural modes of vibration of uniform elliptic plates with clamped, simply supported and free boundaries are investigated using Rayleigh-Ritz method. A modified polar coordinate system is used to investigate the problem. Energy expressions in Cartesian coordinate system are transformed into the modified polar coordinate system. Boundary characteristic orthogonal polynomials in the radial direction, and trigonometric functions in the angular direction are used to express the deflection of the plate. These deflection shapes are classified into four basic categories, depending on its symmetrical or antisymmetrical property about the major and minor axes of the ellipse. The first six natural modes in each of the above categories are presented in the form of contour plots.


2016 ◽  
Vol 33 (4) ◽  
pp. 697-712 ◽  
Author(s):  
R. Andrew Weekley ◽  
R. Kent Goodrich ◽  
Larry B. Cornman

AbstractAn image-processing algorithm has been developed to identify aerosol plumes in scanning lidar backscatter data. The images in this case consist of lidar data in a polar coordinate system. Each full lidar scan is taken as a fixed image in time, and sequences of such scans are considered functions of time. The data are analyzed in both the original backscatter polar coordinate system and a lagged coordinate system. The lagged coordinate system is a scatterplot of two datasets, such as subregions taken from the same lidar scan (spatial delay), or two sequential scans in time (time delay). The lagged coordinate system processing allows for finding and classifying clusters of data. The classification step is important in determining which clusters are valid aerosol plumes and which are from artifacts such as noise, hard targets, or background fields. These cluster classification techniques have skill since both local and global properties are used. Furthermore, more information is available since both the original data and the lag data are used. Performance statistics are presented for a limited set of data processed by the algorithm, where results from the algorithm were compared to subjective truth data identified by a human.


Healthcare ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 33
Author(s):  
Norbert Hosten ◽  
Robin Bülow ◽  
Henry Völzke ◽  
Martin Domin ◽  
Carsten Oliver Schmidt ◽  
...  

The Study of Health in Pomerania (SHIP), a population-based study from a rural state in northeastern Germany with a relatively poor life expectancy, supplemented its comprehensive examination program in 2008 with whole-body MR imaging at 1.5 T (SHIP-MR). We reviewed more than 100 publications that used the SHIP-MR data and analyzed which sequences already produced fruitful scientific outputs and which manuscripts have been referenced frequently. Upon reviewing the publications about imaging sequences, those that used T1-weighted structured imaging of the brain and a gradient-echo sequence for R2* mapping obtained the highest scientific output; regarding specific body parts examined, most scientific publications focused on MR sequences involving the brain and the (upper) abdomen. We conclude that population-based MR imaging in cohort studies should define more precise goals when allocating imaging time. In addition, quality control measures might include recording the number and impact of published work, preferably on a bi-annual basis and starting 2 years after initiation of the study. Structured teaching courses may enhance the desired output in areas that appear underrepresented.


2021 ◽  
Vol 12 (1) ◽  
pp. 165-172
Author(s):  
Kan Shi ◽  
Shuai Lin ◽  
Yan'an Yao

Abstract. As a type of spatial transmission mechanism, noncircular bevel gears can be used to transfer the power and motion with a variable transmission ratio between intersecting axes. In this paper, utilizing the spherical triangle theorem and meshing principle, the parametric equations of the contact ratio are established in the space polar coordinate system. Two innovative methods are proposed to analyze the contact ratio by using the rotation angle of the driving (driven) gears and the arc length of pitch curve as pure rolling. In the case of modified gear and X-zero gear, whether the noncircular bevel gear is continuously driven is deduced. The simulation transmission ratio curve and theoretical transmission ratio curve are compared to verify the rationality of the design.


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