scholarly journals The Use of Deep Learning to Predict Stroke Patient Mortality

2019 ◽  
Vol 16 (11) ◽  
pp. 1876 ◽  
Author(s):  
Songhee Cheon ◽  
Jungyoon Kim ◽  
Jihye Lim
Keyword(s):  
Neural Network ◽  
Health Behavior ◽  
Deep Neural Network ◽  
Service Use ◽  
Medical Service ◽  
Area Under The Curve ◽  
Principal Component ◽  
Warning Signs ◽  
Imaging Data ◽  
Stroke Incidence

The increase in stroke incidence with the aging of the Korean population will rapidly impose an economic burden on society. Timely treatment can improve stroke prognosis. Awareness of stroke warning signs and appropriate actions in the event of a stroke improve outcomes. Medical service use and health behavior data are easier to collect than medical imaging data. Here, we used a deep neural network to detect stroke using medical service use and health behavior data; we identified 15,099 patients with stroke. Principal component analysis (PCA) featuring quantile scaling was used to extract relevant background features from medical records; we used these to predict stroke. We compared our method (a scaled PCA/deep neural network [DNN] approach) to five other machine-learning methods. The area under the curve (AUC) value of our method was 83.48%; hence; it can be used by both patients and doctors to prescreen for possible stroke.

scholarly journals A Deep Neural Network-Based Method for Prediction of Dementia Using Big Data

2021 ◽  
Vol 18 (10) ◽  
pp. 5386
Author(s):  
Jungyoon Kim ◽  
Jihye Lim
Keyword(s):  
Neural Network ◽  
Health Behavior ◽  
Deep Neural Network ◽  
Medical Service ◽  
Financial Burden ◽  
Area Under The Curve ◽  
Principal Component ◽  
Machine Learning Algorithms ◽  
Service Usage ◽  
Usage Data

The rise in dementia among the aging Korean population will quickly create a financial burden on society, but timely recognition of early warning for dementia and proper responses to the occurrence of dementia can enhance medical treatment. Health behavior and medical service usage data are relatively more accessible than clinical data, and a prescreening tool with easily accessible data could be a good solution for dementia-related problems. In this paper, we apply a deep neural network (DNN) to prediction of dementia using health behavior and medical service usage data, using data from 7031 subjects aged over 65 collected from the Korea National Health and Nutrition Examination Survey (KNHANES) in 2001 and 2005. In the proposed model, principal component analysis (PCA) featuring and min/max scaling are used to preprocess and extract relevant background features. We compared our proposed methodology, a DNN/scaled PCA, with five well-known machine learning algorithms. The proposed methodology shows 85.5% of the area under the curve (AUC), a better result than that using other algorithms. The proposed early prescreening method for possible dementia can be used by both patients and doctors.

scholarly journals A Deep Neural Network-Based Method for Early Detection of Osteoarthritis Using Statistical Data

2019 ◽  
Vol 16 (7) ◽  
pp. 1281 ◽  
Author(s):  
Jihye Lim ◽  
Jungyoon Kim ◽  
Songhee Cheon
Keyword(s):  
Neural Network ◽  
Health Behavior ◽  
Deep Neural Network ◽  
Statistical Data ◽  
Medical Images ◽  
Area Under The Curve ◽  
Principal Component ◽  
Medical Utilization ◽  
Correct Prediction ◽  
Promising Tool

A large number of people suffer from certain types of osteoarthritis, such as knee, hip, and spine osteoarthritis. A correct prediction of osteoarthritis is an essential step to effectively diagnose and prevent severe osteoarthritis. Osteoarthritis is commonly diagnosed by experts through manual inspection of patients’ medical images, which are usually collected in hospitals. Checking the occurrence of osteoarthritis is somewhat time-consuming for patients. In addition, the current studies are focused on automatically detecting osteoarthritis through image-based deep learning algorithms. This needs patients’ medical images, which requires patients to visit the hospital. However, medical utilization and health behavior information as statistical data are easier to collect and access than medical images. Using indirect statistical data without any medical images to predict the occurrence of diverse forms of OA can have significant impacts on pro-active and preventive medical care. In this study, we used a deep neural network for detecting the occurrence of osteoarthritis using patient’s statistical data of medical utilization and health behavior information. The study was based on 5749 subjects. Principal component analysis with quantile transformer scaling was employed to generate features from the patients’ simple background medical records and identify the occurrence of osteoarthritis. Our experiments showed that the proposed method using deep neural network with scaled PCA resulted in 76.8% of area under the curve (AUC) and minimized the effort to generate features. Hence, this methos can be a promising tool for patients and doctors to prescreen for possible osteoarthritis to reduce health costs and patients’ time in hospitals.

scholarly journals DNN-m6A: A Cross-Species Method for Identifying RNA N6-Methyladenosine Sites Based on Deep Neural Network with Multi-Information Fusion

Genes ◽  
2021 ◽  
Vol 12 (3) ◽  
pp. 354
Author(s):  
Lu Zhang ◽  
Xinyi Qin ◽  
Min Liu ◽  
Ziwei Xu ◽  
Guangzhong Liu
Keyword(s):  
Neural Network ◽  
Deep Neural Network ◽  
Area Under The Curve ◽  
Nucleotide Composition ◽  
Computational Method ◽  
Feature Subset ◽  
Accurate Identification ◽  
Genome Wide ◽  
Dinucleotide Composition ◽  
Optimal Feature Subset

As a prevalent existing post-transcriptional modification of RNA, N6-methyladenosine (m6A) plays a crucial role in various biological processes. To better radically reveal its regulatory mechanism and provide new insights for drug design, the accurate identification of m6A sites in genome-wide is vital. As the traditional experimental methods are time-consuming and cost-prohibitive, it is necessary to design a more efficient computational method to detect the m6A sites. In this study, we propose a novel cross-species computational method DNN-m6A based on the deep neural network (DNN) to identify m6A sites in multiple tissues of human, mouse and rat. Firstly, binary encoding (BE), tri-nucleotide composition (TNC), enhanced nucleic acid composition (ENAC), K-spaced nucleotide pair frequencies (KSNPFs), nucleotide chemical property (NCP), pseudo dinucleotide composition (PseDNC), position-specific nucleotide propensity (PSNP) and position-specific dinucleotide propensity (PSDP) are employed to extract RNA sequence features which are subsequently fused to construct the initial feature vector set. Secondly, we use elastic net to eliminate redundant features while building the optimal feature subset. Finally, the hyper-parameters of DNN are tuned with Bayesian hyper-parameter optimization based on the selected feature subset. The five-fold cross-validation test on training datasets show that the proposed DNN-m6A method outperformed the state-of-the-art method for predicting m6A sites, with an accuracy (ACC) of 73.58%–83.38% and an area under the curve (AUC) of 81.39%–91.04%. Furthermore, the independent datasets achieved an ACC of 72.95%–83.04% and an AUC of 80.79%–91.09%, which shows an excellent generalization ability of our proposed method.

scholarly journals Centered Kernel Alignment Enhancing Neural Network Pretraining for MRI-Based Dementia Diagnosis

2016 ◽  
Vol 2016 ◽  
pp. 1-10 ◽  
Author(s):  
David Cárdenas-Peña ◽  
Diego Collazos-Huertas ◽  
German Castellanos-Dominguez
Keyword(s):  
Neural Network ◽  
Characteristic Curve ◽  
Principal Component ◽  
Imaging Data ◽  
Resonance Imaging ◽  
Dementia Diagnosis ◽  
Target Matrix ◽  
Computer Aided ◽  
Artificial Neural Network Ann ◽  
Aided Diagnosis

Dementia is a growing problem that affects elderly people worldwide. More accurate evaluation of dementia diagnosis can help during the medical examination. Several methods for computer-aided dementia diagnosis have been proposed using resonance imaging scans to discriminate between patients with Alzheimer’s disease (AD) or mild cognitive impairment (MCI) and healthy controls (NC). Nonetheless, the computer-aided diagnosis is especially challenging because of the heterogeneous and intermediate nature of MCI. We address the automated dementia diagnosis by introducing a novel supervised pretraining approach that takes advantage of the artificial neural network (ANN) for complex classification tasks. The proposal initializes an ANN based on linear projections to achieve more discriminating spaces. Such projections are estimated by maximizing the centered kernel alignment criterion that assesses the affinity between the resonance imaging data kernel matrix and the label target matrix. As a result, the performed linear embedding allows accounting for features that contribute the most to the MCI class discrimination. We compare the supervised pretraining approach to two unsupervised initialization methods (autoencoders and Principal Component Analysis) and against the best four performing classification methods of the 2014CADDementiachallenge. As a result, our proposal outperforms all the baselines (7% of classification accuracy and area under the receiver-operating-characteristic curve) at the time it reduces the class biasing.

scholarly journals Predictive Model for Brain Stroke in CT using Deep Neural Network

2020 ◽  
Vol 9 (1) ◽  
pp. 2011-2017
Keyword(s):  
Neural Network ◽  
Machine Learning ◽  
Deep Neural Network ◽  
Principal Component ◽  
World Population ◽  
Neural Network Learning ◽  
Machine Learning Classification ◽  
Network Learning ◽  
Brain Stroke ◽  
Aging World

The increasing in the incidence of stroke with aging world population would quickly place an economic burden on society. In proposed method we use different machine learning classification algorithms like Decision Tree, Deep Neural Network Learning, Maximum Expectization , Random Forest and Gaussian Naïve Bayesian Classifier is used with associated number of attributes to estimate the occurrence of stroke disease. The present research, mainly PCA (Principal Component Analysis) algorithm is used to limit the performance and scaling used to be adopted to extract splendid context statistics from medical records. We used those reduced features to determine whether or not the patient has a stroke disorder. We compared proposed method Deep neural network learning classifier with other machine-learning methods with respect to accuracy, sensitivity and specificity that yields 86.42%, 74.89 and 88.49% respectively. Hence it can be with the aid of both patients and medical doctors to treat viable stroke.

CARDIAC ADVANCED ARRYTHMIA PREDICTION SYSTEMS- CAAPS

2021 ◽  
pp. 54-55
Author(s):  
Pradeep Kumar Radhakrishnan ◽  
Gayathri Ananyajyothi Ambat ◽  
Saihrudya Samhita ◽  
Murugan U S ◽  
Tarig Ali ◽  
...  
Keyword(s):  
Neural Network ◽  
Principal Component Analysis ◽  
Support Vector Machine ◽  
Ventricular Arrhythmias ◽  
Deep Neural Network ◽  
Principal Component ◽  
Support Vector ◽  
Discrete Wavelet ◽  
Term Memory

There is a constant search for novel methods of classication and predicting cardiac rhythm disorders or arrhythmias. We prefer to classify them as wide complex tachyarrhythmia's or ventricular arrhythmias inclusive of malignant ventricular arrhythmias which with hemodynamic compromise is usually life threatening. Long term and fatality predictions warranting AICD implantation are already available. We have a novel method and robust algorithm with preprocessing and optimal feature selection from ECG signal analysis for such rhythm disorders. Variability of ECG recording makes predictability analysis challenging especially when execution time is of prime importance in tackling resuscitative attempts for MVA. Noisy data needs ltering and preprocessing for effective analysis. Portable devices need more of this ltering prior to data input. Deterministic probabilistic nite state automata (DPFA) which generates a probability strings from the broad morphologic patterns of an ECG can generate a classier data for the algorithm without preprocessing for atrial high rate episodes (AHRE). DPFA can be effectively used for atrial tachyarrhythmias for predictive analysis. The method we suggest is use of optimal classier set for prediction of malignant ventricular arrhythmias and use of DFPA for atrial arrhythmias. Here traditional practices of heart rate variability based support vector machine (SVM), discrete wavelet transform (DWT), principal component analysis (PCA), deep neural network (DNN), convoutional neural network (CNN) or CNN with long term memory (LSTM) can be outperformed. AICD - automatic implantable cardiac debrillator, MVA - Malignant Ventricular Arrhythmias, VT - ventricular tachycardia, VF - ventricular brillation,DFPA deterministic probabilistic nite state automata, SVM -Support Vector Machine, DWT discrete wavelet transform, PCA principal component analysis, DNN deep neural network, CNN convoutional neural network, Convoutional LSTM Long short term memory,RNN recurrent neural network

scholarly journals Employing Robust Principal Component Analysis for Noise-Robust Speech Feature Extraction in Automatic Speech Recognition with the Structure of a Deep Neural Network

2018 ◽  
Vol 1 (3) ◽  
pp. 28 ◽  
Author(s):  
Jeih-weih Hung ◽  
Jung-Shan Lin ◽  
Po-Jen Wu
Keyword(s):  
Neural Network ◽  
Principal Component Analysis ◽  
Speech Recognition ◽  
Automatic Speech Recognition ◽  
Deep Neural Network ◽  
Principal Component ◽  
Component Analysis ◽  
Robust Principal Component Analysis ◽  
Speech Feature ◽  
Noise Robust

In recent decades, researchers have been focused on developing noise-robust methods in order to compensate for noise effects in automatic speech recognition (ASR) systems and enhance their performance. In this paper, we propose a feature-based noise-robust method that employs a novel data analysis technique—robust principal component analysis (RPCA). In the proposed scenario, RPCA is employed to process a noise-corrupted speech feature matrix, and the obtained sparse partition is shown to reveal speech-dominant characteristics. One apparent advantage of using RPCA for enhancing noise robustness is that no prior knowledge about the noise is required. The proposed RPCA-based method is evaluated with the Aurora-4 database and a task using a state-of-the-art deep neural network (DNN) architecture as the acoustic models. The evaluation results indicate that the newly proposed method can provide the original speech feature with significant recognition accuracy improvement, and can be cascaded with mean normalization (MN), mean and variance normalization (MVN), and relative spectral (RASTA)—three well-known and widely used feature robustness algorithms—to achieve better performance compared with the individual component method.

scholarly journals Internal Crack Prediction of Continuous Casting Billet Based on Principal Component Analysis and Deep Neural Network

Metals ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 1976
Author(s):  
Leilei Zou ◽  
Jiangshan Zhang ◽  
Yanshen Han ◽  
Fanzheng Zeng ◽  
Quanhui Li ◽  
...  
Keyword(s):  
Neural Network ◽  
Principal Component Analysis ◽  
Continuous Casting ◽  
Deep Neural Network ◽  
Principal Component ◽  
Component Analysis ◽  
Learning Ability ◽  
Internal Crack ◽  
Strong Nonlinearity ◽  
Neural Network Models

The accurate prediction of internal cracks in steel billets is of great importance for the stable production of continuous casting. However, it is challenging, owing to the strong nonlinearity, and coupling among continuous casting process parameters. In this study, an internal crack prediction model based on the principal component analysis (PCA) and deep neural network (DNN) was proposed by collecting sufficient industrial data. PCA was used to reduce the dimensionality of the factors influencing the internal cracks, and the obtained principal components were used as DNN input variables. The 5-fold cross-validation results demonstrate that the prediction accuracy of the DNN model is 92.2%, which is higher than those of the decision tree (DT), extreme learning machine (ELM), and backpropagation (BP) neural network models. Moreover, the variance analysis showed that the prediction results of the DNN model were more stable. The PCA-DNN model can provide a useful reference for real production, owing to its strong learning ability and fault-tolerant ability.

scholarly journals Online COVID-19 diagnosis with chest CT images: Lesion-attention deep neural networks

2020 ◽  
Author(s):  
Bin Liu ◽  
Xiaoxue Gao ◽  
Mengshuang He ◽  
Fengmao Lv ◽  
Guosheng Yin
Keyword(s):  
Neural Network ◽  
Deep Neural Network ◽  
Binary Classification ◽  
Area Under The Curve ◽  
Ct Images ◽  
Chest Ct ◽  
Diagnostic Tools ◽  
Ct Image ◽  
Medical Systems ◽  
Negative Case

Chest computed tomography (CT) scanning is one of the most important technologies for COVID-19 diagnosis and disease monitoring, particularly for early detection of coronavirus. Recent advancements in computer vision motivate more concerted efforts in developing AI-driven diagnostic tools to accommodate the enormous demands for the COVID-19 diagnostic tests globally. To help alleviate burdens on medical systems, we develop a lesion-attention deep neural network (LA-DNN) to predict COVID-19 positive or negative with a richly annotated chest CT image dataset. Based on the textual radiological report accompanied with each CT image, we extract two types of important information for the annotations: One is the indicator of a positive or negative case of COVID-19, and the other is the description of five lesions on the CT images associated with the positive cases. The proposed data-efficient LA-DNN model focuses on the primary task of binary classification for COVID-19 diagnosis, while an auxiliary multi-label learning task is implemented simultaneously to draw the model's attention to the five lesions associated with COVID-19. The joint task learning process makes it a highly sample-efficient deep neural network that can learn COVID-19 radiology features more effectively with limited but high-quality, rich-information samples. The experimental results show that the area under the curve (AUC) and sensitivity (recall), precision, and accuracy for COVID-19 diagnosis are 94.0%, 88.8%, 87.9%, and 88.6% respectively, which reach the clinical standards for practical use. A free online system is currently alive for fast diagnosis using CT images at the website https://www.covidct.cn/, and all codes and datasets are freely accessible at our github address.

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