scholarly journals Non-Carcinogenic Health Risk Assessment due to Fluoride Exposure from Tea Consumption in Iran Using Monte Carlo Simulation

2019 ◽  
Vol 16 (21) ◽  
pp. 4261 ◽  
Author(s):  
Mohammad Amin Karami ◽  
Yadollah Fakhri ◽  
Shahabaldin Rezania ◽  
Abdol Azim Alinejad ◽  
Ali Akbar Mohammadi ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Health Risk ◽  
Health Risk Assessment ◽  
Environmental Protection Agency ◽  
Hazard Quotient ◽  
Age Groups ◽  
Fluoride Concentration ◽  
Daily Intake ◽  
Carcinogenic Risk ◽  
Fluoride Exposure

Excessive intake of fluoride can cause adverse health effects. Consumption of tea as a popular drink could be a potential source of fluoride exposure to humans. This research aimed to evaluate the fluoride concentration in tea among the Iranian people using the available data in the literature and to assess the health risk related to the consumption of tea in men, women, and children. The health risk assessment was conducted using the chronic daily intake and hazard quotient according to the approach suggested by the Environmental Protection Agency. The fluoride content in published studies varied noticeably, ranging from 0.13 to 3.27 mg/L. The results revealed that the hazard quotient (HQ) in age groups of women (21–72 years) and children (0–11 years) was within the safe zone (HQ < 1) which showed that there was no potential of non-carcinogenic risk associated with drinking tea in these groups. However, in one case of the men (21–72 years), the HQ > 1 which shows a probable risk of fluorosis. The order of non-carcinogenic health risks in the studied groups was in the order of men > women > children. The results of this can be useful for organizations with the responsibility of human health promotion.

scholarly journals Health risk assessment by trace elements in an aquatic system in midwestern Brazil

2021 ◽  
Vol 10 (10) ◽  
pp. e398101019037
Author(s):  
Raylane Pereira Gomes ◽  
Thais Reis Oliveira ◽  
Aline Rodrigues Gama ◽  
Fernando Santos Lima ◽  
José Daniel Gonçalves Vieira ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Trace Elements ◽  
Health Risk ◽  
Health Risk Assessment ◽  
Socioeconomic Development ◽  
Hazard Quotient ◽  
Hazard Index ◽  
Carcinogenic Risk ◽  
Risk Indices ◽  
Daily Dose

Water is an important asset for the maintenance of life and socioeconomic development. Aquatic environments have been anthropized, receiving a large polluting load, mainly from trace elements.This study investigates the occurrence of health risks caused by 15 trace elements in the surface water of João Leite stream. Health risk indices were evaluated as average daily dose (ADD), hazard quotient (HQ), hazard index and carcinogenic risk. The risk analysis to human health of the stream João Leite water, indicated that the ADDingestion for the adults had the highest for Fe 1.86E-00 µg/kg/day and lower value for Be 8.0E-05 µg/kg/day. On the other hand, of ADDdermal the highest value was for Fe 5.02E-02 µg/kg/day and, the smallest for Sb 1.54E-05 µg/kg/day. For children to ADDingestion obtained was obtained the highest Fe value 2.60E-00 µg/kg/day and smaller for Be 1.12E-04 µg/kg/day. For ADDdermal the highest value was for Fe 8.58E-02 µg/kg/day and smaller for Sb 2.64E-05 µg/kg/day. HQ for adults ranged from 1.61E-05 to 2.97E-01 for HQingestion and 7.71E-06 to 1.01E-01 for HQdermal. For children 2.25E-05 to 3.74E-01 for HQingestion and 1.32E-05 to 1.73E-01 for HQdermal. The health risk assessment showed that for children, the trace elements present in water have a potentially adverse effect on non-carcinogenic health. The carcinogenic risks were unacceptable for both children and adults. Thus, it is recommended that the use of these waters be limited and that measures be taken to minimize pollution by trace elements.

scholarly journals Carcinogenic and Non-Carcinogenic Risk Assessment of Heavy Metals in Water Resources of North East of Iran in 2018

2021 ◽  
Author(s):  
Mahdi Sadeghi ◽  
Mina Noroozi
Keyword(s):  
Heavy Metals ◽  
Risk Assessment ◽  
Health Risk ◽  
Water Samples ◽  
Environmental Protection Agency ◽  
Hazard Quotient ◽  
Carcinogenic Risk ◽  
High Rate ◽  
Health Concern ◽  
North East

Introduction: Contamination of water with heavy metals has turned into a health concern, particularly in the developing countries. In this study, concentration of heavy metals and associated carcinogenic and non- carcinogenic risk was investigated in water samples collected from Gonbad-e Kavus, a high-risk area for cancer. Materials and Methods: Samples were collected from Gorgan River, Golestan reservoir and wells around villages with high prevalence in 2018. Samples were analysed through inductively coupled plasma mass spectrometry. After determining the concentration of heavy metals in water samples from different sources, health risk assessment was carried out according to the Environmental Protection Agency.  Results: Arsenic in samples 6-9 was higher than 10 µg/L, calcium and magnesium in sample 5 was higher than 200 mg/L and 150 mg/L respectively, and sodium in all samples was higher than 50 mg/L.  According to the findings, these concentrations were higher than the maximum allowed limit in most water samples. Hazard quotient (HQ) in samples 8 and 9 were associated with arsenic and health risk in sample 1 was related to antimony. Furthermore, since all samples contained high amounts of lithium, water from this area better should not be consumed by children older than one year. Conclusion: Given the high rate of arsenic contamination, consumption of water in the study area could be health threatening for all individuals and is not recommended for children. This highlights the need for taking immediate actions to review the water treatment process and ensure safety of the drinking water in this area.

scholarly journals Lead exposure through eggs in Iran: health risk assessment

2021 ◽  
Vol 9 (1) ◽  
pp. 184-191
Author(s):  
Sajad Faryabi ◽  
Mohsen Ghorbiani ◽  
Hadi Haghbin Nazarpak ◽  
Azadeh Rashidimehr
Keyword(s):  
Risk Assessment ◽  
Health Risk ◽  
Human Health ◽  
Health Risk Assessment ◽  
Human Health Risk ◽  
Daily Intake ◽  
Carcinogenic Risk ◽  
Egg Consumption ◽  
Safe Limits ◽  
Mashhad City

Introduction. Contamination of food, including animal protein sources, with heavy metals is a major threat to humans. The aim of this research was to determine lead concentrations in eggs from different Iranian regions and assess risks to human health. Study objects and methods. In this study, lead concentrations in eggs produced at laying hen farms in Qom, Isfahan (Kashan city), and Khorasan Razavi (Mashhad city) provinces were measured by an atomic absorption device. Health risk was estimated using the Human Health Risk Assessment (HHRA) model. Results and discussion. The levels of lead in eggs were significantly different (P ≤ 0.05) among the three regions. They were lower than the permissible limit (0.1 mg/kg) for Kashan (0.0756 mg/kg) and Mashhad (0.0633 mg/kg), but eggs from Qom contained 0.1163 mg/kg of lead. In all the three regions, the estimated daily intake (EDI) of lead was lower than the maximum tolerable daily intake (MTDI), indicating no health risk for lead through egg consumption among Iranian consumers. Also, no risks were detected for adults in terms of non-cancer risk, or target hazard quotients (THQ), and carcinogenic risk (CR) of lead (THQ < 1 and CR < 10–6). Conclusion. The results of this study indicated that lead health risk through egg consumption is within safe limits. However, the nutritional importance and high consumption of eggs among households necessitate a more careful monitoring of lead concentrations to meet public health requirements.

scholarly journals Health Risk Assessment of Selected Heavy Metals in Cocoyam from Three Quarry Sites in Old Netim, Cross River State, Nigeria

2021 ◽  
pp. 57-66
Author(s):  
P. O. Odey ◽  
F. C. Anacletus ◽  
M. O. Wegwu
Keyword(s):  
Heavy Metals ◽  
Risk Assessment ◽  
Health Risk ◽  
Health Risk Assessment ◽  
Hazard Quotient ◽  
Daily Intake ◽  
Atomic Absorption Spectrophotometry ◽  
Target Hazard Quotient ◽  
Cross River ◽  
Cross River State

This study assessed health risk assessment of heavy metals in cocoyam from three quarry sites in Akamkpa LGA, Cross River State, Nigeria. Cocoyam tubers were obtained from three quarry sites in Oban Okoroba, each 4.5 kilometers apart and 20 kilometers from the control site. Cocoyam tubers were obtained from 0km, 0.2km, 0.4km, and 0.6km. Atomic Absorption Spectrophotometry (AAS) was used to determine the content of Lead (Pb), Cadmium (Cd), Copper (Cu), Arsenic (As) and Manganese (Mn), showing relative abundance across all sites and samples in the sequence Mn > Cu > Pb > As > Cd. Quarry site D had highest levels of Mn, As and Cu (50.003 ± 5.478 mgkg-1, 0.207 ± 0.184 and 4.522 ± 1.204mgkg-1). Quarry site C and B respectively had the highest levels of Pb and Cd (1.136 ± 0.267 mgkg-1 and 0.041 ± 0.028 mgkg-1). Results of Estimated Daily Intake (EDI), Target Hazard Quotient (THQ) and Life Carcinogenic Risk (LCR) showed ingestion of cocoyam tubers from Old Netim is safe and devoid of non-carcinogenic and carcinogenic risks. THI on the other hand revealed non-carcinogenic threat may result from prolonged ingestion of cocoyam tubers cultivated within quarry sites in Old Netim.

scholarly journals Bioaccumulation of Antimony and Arsenic in Vegetables and Health Risk Assessment in the Superlarge Antimony-Mining Area, China

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Defang Zeng ◽  
Saijun Zhou ◽  
Bozhi Ren ◽  
Tengshu Chen
Keyword(s):  
Risk Assessment ◽  
Health Risk ◽  
Health Risk Assessment ◽  
Health Risks ◽  
Hazard Quotient ◽  
Daily Intake ◽  
Mining Area ◽  
Coriandrum Sativum ◽  
Potential Health ◽  
Safe Limit

Heavy metal pollution in soils caused by mining and smelting has attracted worldwide attention for its potential health risks to residents. This paper studies the concentrations and accumulations of Sb and As in both soils and vegetables and the human health risks of Sb and As in vegetables from Xikuangshan (XKS) Sb mine, Hunan, China. Results showed that the soils were severely polluted by Sb and As; Sb and As have significant positive correlation. Sb and As concentrations in vegetables were quite different:Coriandrum sativumL. was the highest in Sb,Allium fistulosumL. was the highest in As, andBrassica pekinensisL. was the lowest in both Sb and As;Daucus carotaL. andCoriandrum sativumL. showed advantage in accumulating Sb and As;Coriandrum sativumL. had higher capacity of redistributing Sb and As within the plant. Health risk assessment results showed that the hazard quotient (HQ) values of Sb and As in vegetables were in the ranges of 1.61–3.33 and 0.09–0.39, respectively; the chronic daily intake (CDI) and hazard quotient (HQ) values of Sb were over the safe limit recommended by FAO and WHO, indicating that long-term consumption of vegetables from the surrounding soils of XKS mine may bring health risks to residents.

scholarly journals Concentration of cadmium, arsenic, and lead in rice (Oryza sativa) and probabilistic health risk assessment: A case study in Hormozgan province, Iran

2021 ◽  
Vol 8 (2) ◽  
pp. 67-75
Author(s):  
Leila Rezaei ◽  
Vali Alipour ◽  
Parisa Sharafi ◽  
Hamidreza Ghaffari ◽  
Amene Nematollahi ◽  
...  
Keyword(s):  
Heavy Metals ◽  
Risk Assessment ◽  
Health Risk ◽  
Health Risk Assessment ◽  
Graphite Furnace ◽  
Hazard Quotient ◽  
Carcinogenic Risk ◽  
Target Hazard Quotient ◽  
Toxic Heavy Metals ◽  
Rice Samples

Background: The presence of toxic heavy metals in cereal grains like rice is one of the main human and environmental health concerns. Their importance is because of their non-biodegradability nature, high half-time, and bioaccumulation ability in the human body. Among heavy metals, cadmium (Cd), lead (Pb), and arsenic (As) are most critical, so their concentrations in rice were evaluated in this study. Methods: In this study, the concentration of Cd and Pb was determined by graphite-furnace atomic absorption spectrometer (GF-AAS), while the concentration of As was measured by atomic spectrum poll after acid digestion of the milled rice samples. The probabilistic health risk assessment of Cd, As, and Pb through consumption of different types of rice including local rice and two types imported from India (IND) and Pakistan (PAK), was estimated for the adults in Hormozgan province using Monte Carlo simulation (MCS) technique. Results: It was revealed that the concentrations of all Cd, As, and Pb in the local rice samples were lower than those in the PAK and IND samples. The average concentration of As, Pb, and Cd in the rice samples were 0.045, 0.057, and 0.022 mg/kg, respectively. The estimated total target hazard quotient (TTHQ) for this population was lower than 1, representing negligible non-carcinogenic risk through rice consumption. However, total carcinogenic risk (TCR) via As intake showed a considerable carcinogenic risk (TCR > 1E-4) for this population. Conclusion: According to the results, it is necessary to perform continuous monitoring for concentration of Cd, As, and Pb especially in the imported rice samples.

scholarly journals The Condition of Air Pollution in Kraków, Poland, in 2005–2020, with Health Risk Assessment

2020 ◽  
Vol 17 (17) ◽  
pp. 6063 ◽  
Author(s):  
Paulina Traczyk ◽  
Agnieszka Gruszecka-Kosowska
Keyword(s):  
Risk Assessment ◽  
Health Risk ◽  
Environmental Protection ◽  
Health Risk Assessment ◽  
Environmental Protection Agency ◽  
Human Health Risk ◽  
Carcinogenic Risk ◽  
Air Pollutant ◽  
Risk Indices ◽  
Study Results

Aims: Air quality changes with human health risk assessment were investigated. Methods: The measurement results obtained by the Regional Environmental Protection Inspectorate (REPI) in Kraków and our deposited particulate-matter (PM) analysis, as well as United States Environmental Protection Agency (USEPA) methodology of risk assessment were used in the study. Results: Annual pollutant contents kept decreasing, with the exception of O3. However, the permissible annual levels were exceeded in the cases of PM10, PM2.5, and NO2. Increased contents of SO2, CO, C6H6, PM10, and PM2.5, as well as of As, Pb, Cd, Ni, and polycyclic aromatic hydrocarbons (PAHs) in PM particles during winter months indicated that house heating was the source of pollution. Due to no significant change in the monthly NO2 contents, this measurement was used as an indicator of traffic sources of pollution. In winter months, the allowable 24 h PM2.5 and PM10 contents were constantly exceeded. PM was identified as the most significant air pollutant. Enrichment factors revealed that deposited PM was enriched with heavy metals. The potential ecological risk (ERI) was determined to be very high for Cd, considerable for Zn, and low for As, Co, Cr, Cu, Ni, Pb, and Tl. The total non-carcinogenic risk indices (HQ) for both adults (HQ = 15.0) and children (HQ = 26.4) exceeded the acceptable value of 1. The total carcinogenic risk indices (CR) for both adults (CR = 1.51 × 10−4) and children (CR = 1.77 × 10−4) exceeded the acceptable level of 1 × 10−4. Conclusions: In the years 2005–2020, a general decreasing tendency of annual pollutant contents was observed. However, the permissible contaminant contents were still exceeded. PM2.5, BaP, PM10, and NO2 were determined as the most dangerous pollutants in inhalational pathway.

scholarly journals Health Risk Assessment of Mercury Exposure from Fish Consumption in Munduruku Indigenous Communities in the Brazilian Amazon

2021 ◽  
Vol 18 (15) ◽  
pp. 7940
Author(s):  
Ana Claudia Santiago de Vasconcellos ◽  
Gustavo Hallwass ◽  
Jaqueline Gato Bezerra ◽  
Angélico Nonato Serrão Aciole ◽  
Heloisa Nascimento de Moura Meneses ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Health Risk ◽  
Health Risk Assessment ◽  
Environmental Protection Agency ◽  
Fish Consumption ◽  
Daily Intake ◽  
Indigenous Communities ◽  
Trophic Levels ◽  
World Health ◽  
Health Organization

Fish serves as the principal source of animal protein for the indigenous people of the Amazon, ensuring their food and nutritional security. However, gold mining causes mercury (Hg) contamination in fish, and consequently increases health risks associated with fish consumption. The aim of this study was to assess the health risk attributed to the consumption of mercury-contaminated fish by Munduruku indigenous communities in the Middle-Tapajós Region. Different fish species were collected in the Sawré Muybu Indigenous Land to determine mercury levels. The health risk assessment was carried out according to the World Health Organization (WHO 2008) methodology and different scenarios were built for counterfactual analysis. Eighty-eight fish specimens from 17 species and four trophic levels were analyzed. Estimates of Hg ingestion indicated that the methylmercury daily intake exceeds the U.S. EPA (United States Environmental Protection Agency) (2000) reference dose from 3 to 25-fold, and up to 11 times the FAO (Food and Agriculture Organization)/WHO (2003) dose recommendation. In all situations analyzed, the risk ratio estimates were above 1.0, meaning that the investigated Munduruku communities are at serious risk of harm as a result of ingestion of mercury-contaminated fish. These results indicate that, at present, fish consumption is not safe for this Munduruku population. This hazardous situation threatens the survival of this indigenous population, their food security, and their culture

scholarly journals Evaluation of Chemical Parameters of Urban Drinking Water Quality along with Health Risk Assessment: A Case Study of Ardabil Province, Iran

2021 ◽  
Vol 18 (10) ◽  
pp. 5179
Author(s):  
Reza Aghlmand ◽  
Saeed Rasi Nezami ◽  
Ali Abbasi
Keyword(s):  
Water Quality ◽  
Risk Assessment ◽  
Drinking Water ◽  
Health Risk ◽  
Health Risk Assessment ◽  
Water Distribution ◽  
Hazard Quotient ◽  
Hazard Index ◽  
World Health ◽  
Study Region

In recent years, in addition to water resources’ quantity, their quality has also received much attention. In this study, the quality of the urban water distribution network in northwestern Iran was evaluated using the water quality index (WQI) method. Then, some important trace elements were investigated, and finally, the health risk assessment was evaluated for both carcinogenic elements (Ni, Cd, Cr, Pb, and As) and non-carcinogenic elements (Ca, Mg, Na, K, F, NO3, and Cu) using carcinogenic risk (CR) and hazard quotient (HQ), respectively. In the present study, the WQI was calculated based on both World Health Organization (WHO) and Iranian drinking water standards. Comparing the results of these standards revealed that the WQI based on the Iranian standard was slightly higher. Regarding the calculated WQI for the study region, the status of water quality for drinking consumption is in the good water quality class (25 < WQI < 50). It was observed that Cu and Cd have the highest and lowest concentrations in all sampling points, respectively. Hazard Index (HI) results showed that the non-carcinogenic substances studied had a low risk for both adults and children (<1.0). However, the CR results showed that Ni, Cd, and As were above the desired level for both children and adults. The results of this study can be applied for efficient water management and human health protection programs in the study area.

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