Assessing the Knowledge of Analgesic Drugs Utilization during Pregnancy among Women in Saudi Arabia: A Cross-Sectional Study

Background: Pain is a common compensation mechanism in pregnant women that they may face during gestation due to physiological changes. Paracetamol and non-steroidal anti-inflammatory drugs are the most administered analgesic drugs worldwide. Therefore, safety and efficacy are important measures for the use of analgesics during pregnancy. Objective: Assess the knowledge of analgesic drug utilization among Saudi pregnant women. Method: We conducted a self-administered survey with an electronic questionnaire via Google Drive among a sample of 406 Saudi women. Results: About half of the respondents took analgesics during the first trimester, and 52.5% of women have used analgesics at least once without any medical advice during their gestation. Most participants agreed that paracetamol is the safest and effective analgesic drug during pregnancy, yet 61.8% of women are not aware that analgesics could be detrimental to the fetus if inappropriately administered in the third trimester. Conclusion: Participants have a good perception of the safest and most effective analgesic drug during pregnancy, but they have poor knowledge about analgesics’ side effects.

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Preventive and Curative treatment of malaria during pregnancy in Mali: Evaluation of the Healthcare Professionals based on the Malian National Malaria Control Program (NMCP) Guidelines

Journal of Drug Delivery and Therapeutics ◽

10.22270/jddt.v11i5-s.5092 ◽

2021 ◽

Vol 11 (5-S) ◽

pp. 71-76

Author(s):

Mahamadou BALLO ◽

Karim Traoré ◽

Samou Sidibé ◽

Seidina Diakité ◽

Abdoulaye Guindo ◽

...

Keyword(s):

Pregnant Women ◽

Malaria Transmission ◽

Control Program ◽

Preventive Treatment ◽

First Trimester ◽

Cross Sectional Study ◽

Antimalarial Drugs ◽

Third Trimester ◽

Cross Sectional ◽

In Pregnancy

Malaria infections in pregnancy should be treated promptly with safe and efficacious antimalarial drugs to prevent harmful effects on the mother and fetus. To succeed, the Malian has developed NMCP guidelines for the management of malaria cases in pregnant women. The study aimed at the analysis of the prescription of antimalarial drugs based on the Mali's NMCP guidelines. We conducted a cross-sectional study during malaria transmission season from June to August 2020. The sampling concerned all prescriptions for pregnant women containing at least one antimalarial drug. The frequency of prescription of antimalarial drugs was 85%. 132 (74.16%) were preventive treatments and 46 (25.84%) curative treatments. 30 (90.91%) of pregnant women in the first trimester received one dose of Sulfadoxine-Pyrimethamine. 6 (12.5%) received three doses in the third trimester. Of the 46 antimalarial drugs prescribed for the treatment of uncomplicated malaria, 30 (65.22%) were Artemether-lumefantrine (tablet), 10 (21.74%) were Quinine (tablet). 29 (63.04%) were compliant with NMCP guidelines and 17 (36.96%) were not. The non-compliances concerned 3 prescriptions of Artemether-lumefantrine in the first trimester, 3 and 5 prescriptions of Quinine (tablet) in the second and third trimester respectively and at the end 2 and 4 non-compliances respectively for the prescription of injectable dosage forms of Quinine and Artesunate. This study showed a great noncompliance with the Mali's NMCP guidelines in the prescription of antimalarial in pregnant women. Chemoprophylaxis should be prohibited in the first trimester. Keywords: Curative and Preventive Treatment, Malaria in Pregnancy, Malaria Transmission, Mali

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Antibiotic Prescriptions among China Ambulatory Care Visits of Pregnant Women: A Nationwide Cross-Sectional Study

Antibiotics ◽

10.3390/antibiotics10050601 ◽

2021 ◽

Vol 10 (5) ◽

pp. 601

Author(s):

Houyu Zhao ◽

Mei Zhang ◽

Jiaming Bian ◽

Siyan Zhan

Keyword(s):

Pregnant Women ◽

Ambulatory Care ◽

National Level ◽

Mainland China ◽

Antibiotic Use ◽

First Trimester ◽

Cross Sectional Study ◽

Cross Sectional ◽

Fetal Safety ◽

First Trimester Of Pregnancy

Background: Antibiotic use in pregnant women at the national level has rarely been reported in China. Objectives: We aimed to investigate antibiotic prescriptions during pregnancy in ambulatory care settings in China. Methods: Data of 4,574,961 ambulatory care visits of pregnant women from October 2014 to April 2018 were analyzed. Percentages of Antibiotic prescriptions by different subgroups and various diagnosis categories and proportions of inappropriate antibiotic prescriptions for different subgroups were estimated. Food and Drug Administration (FDA) pregnancy categories were used to describe the antibiotic prescription patterns. The 95% confidence intervals (CIs) were estimated using the Clopper––Pearson method or Goodman method. Results: Among the 4,574,961 outpatient visits during pregnancy, 2.0% (92,514 visits; 95% CI, 2.0–2.0%) were prescribed at least one antibiotic. The percentage of antibiotic prescriptions for pregnant women aged >40 years was 4.9% (95% CI, 4.7–5.0%), whereas that for pregnant women aged 26–30 years was 1.5% (95% CI, 1.4–1.5%). In addition, percentages of antibiotic prescriptions varied among different trimesters of pregnancy, which were 5.4% (95% CI, 5.3–5.4%) for the visits in the first trimester of pregnancy and 0.5% (95% CI, 0.4–0.5%) in the third trimester of pregnancy. Furthermore, the percentages of antibiotic prescriptions substantially varied among different diagnosis categories and nearly three-quarters of antibiotic prescriptions had no clear indications and thus might be inappropriate. In total, 130,308 individual antibiotics were prescribed; among these, 60.4% (95% CI, 60.0–60.8%) belonged to FDA category B, 2.7% (95% CI, 2.1–3.5%) were classified as FDA category D and 16.8% (95% CI, 16.2–17.4%) were not assigned any FDA pregnancy category. Conclusions: Antibiotic prescriptions in ambulatory care during pregnancy were not highly prevalent in mainland China. However, a substantial proportion of antibiotics might have been prescribed without adequate indications. Antibiotics whose fetal safety has not been sufficiently illustrated were widely used in pregnant women.

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Health anxiety and related factors among pregnant women during the COVID-19 pandemic: a cross-sectional study from Iran

BMC Psychiatry ◽

10.1186/s12888-021-03092-7 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Najmieh Saadati ◽

Poorandokht Afshari ◽

Hatam Boostani ◽

Maryam Beheshtinasab ◽

Parvin Abedi ◽

...

Keyword(s):

Pregnant Women ◽

Health Care Providers ◽

Health Anxiety ◽

Cross Sectional Study ◽

Care Providers ◽

Sectional Study ◽

Third Trimester ◽

Related Factors ◽

Cross Sectional ◽

The Third

Abstract Background The COVID-19 pandemic has affected many countries around the world and Iran was no exception. The aim of this study was to evaluate health anxiety of Iranian pregnant women during the COVID-19 pandemic. Methods In this cross-sectional study, 300 pregnant women in different trimesters (n = 100 in each trimester) were recruited. A demographic questionnaire and the Health Anxiety Questionnaire were used to collect data. Scores of < 27, 27–34 and more than 35 were defined as low, moderate and high health anxiety, respectively. Due to nationwide restrictions, data were collected through social media groups. Chi-square tests, ANOVA and multiple linear regression were used to analyze the data. Results Mean (SD) total anxiety scores were 22.3 ± 9.5, 24.6 ± 9.3 and 25.4 ± 10.6 in the first, second and third trimesters of pregnancy, respectively. 9, 13 and 21% of women had severe anxiety in the first, second and third trimesters of pregnancy, respectively. Women in the third trimester had significantly higher health anxiety scores than those in the first trimester (p = 0.045). Conclusion At the time of the COVID-19 pandemic, women in the second and third trimesters of pregnancy were more worried about consequences of disease, but total health anxiety scores were significantly higher among women in the third trimester of pregnancy. Health care providers should pay more attention to the mental health of pregnant women in times of crises such as the COVID-19 pandemic.

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Tokophobia and Anxiety in Pregnant Women during the SARS-CoV-2 Pandemic in Poland—A Prospective Cross-Sectional Study

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph19020714 ◽

2022 ◽

Vol 19 (2) ◽

pp. 714

Author(s):

Marta Makara-Studzińska ◽

Kornelia Zaręba ◽

Natalia Kawa ◽

Dorota Matuszyk

Keyword(s):

Pregnant Women ◽

Human Life ◽

Perinatal Period ◽

Cross Sectional Study ◽

Third Trimester ◽

Cross Sectional ◽

The Third ◽

Main Determinants ◽

High Level ◽

Anxiety Questionnaire

SARS-CoV-2 coronavirus emerged in the world at the end of 2019. The introduction of a number of restrictions had a significant effect on numerous aspects of human life with particular influence being exerted on pregnant women and their sense of security. The study aimed to assess the level of anxiety and its main determinants in women in the third trimester of pregnancy during the coronavirus pandemic. The study technique included the present purposely designed questionnaire, Labor Anxiety Questionnaire (KLPII), and the State-Trait Anxiety Inventory (STAI). The study was conducted in a group of 315 women in the third trimester of pregnancy. A total of 258 women (81.9%) completed the questionnaire in May 2020, and 57 of them (18.1%) completed it in October 2020. The overall analysis of the Labor Anxiety Questionnaire and the STAI inventory revealed a high level of anxiety, particularly situational anxiety, in pregnant women during the SARS-CoV-2 pandemic. The age and financial status of the women were the factors which contributed to the intensification of tokophobia. Women interviewed in October 2020 were characterized by higher tokophobia levels compared to the respondents included in May 2020. It seems justified to in-crease the vigilance in the diagnostics of possible mental disorders in the perinatal period during pandemic.

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Cross-sectional study to assess etiology and associated factors for anaemia during first trimester of pregnancy in Anuradhapura District, Sri Lanka: a protocol

F1000Research ◽

10.12688/f1000research.28226.1 ◽

2021 ◽

Vol 10 ◽

pp. 223

Author(s):

Gayani Amarasinghe ◽

Vasana Mendis ◽

Thilini Agampodi

Keyword(s):

Sri Lanka ◽

Data Collection ◽

Pregnant Women ◽

Associated Factors ◽

First Trimester ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Anaemia In Pregnancy ◽

In Pregnancy

Background: Anaemia in pregnancy, which can lead to adverse maternal and fetal outcomes, is a significant global health problem. Despite Sri Lanka’s strong public health system and commitment towards prevention, maternal anaemia remains a major problem in the country. While prevention is focused on iron deficiency, detailed etiological studies on this topic are scarce. Moreover, estimates of socio demographic and economic factors associated with anaemia in pregnancy, which can provide important clues for anaemia control, are also lacking. This study aims to evaluate the hemoglobin distribution, spatial distribution, etiology and associated factors for anaemia in pregnant women in Anuradhapura, Sri Lanka. Methods: This is a cross sectional study of pregnant women in their first trimester registered for antenatal care from July to September 2019 in the Anuradhapura district. The minimal sample size was calculated to be 1866. Initial data collection has already been carried out in special field clinics for pregnant women between June to October 2019. An interviewer-administered questionnaire, a self-completed dietary questionnaire and an examination checklist were used for data collection. In addition, all participants underwent complete blood count testing. Further investigations are being conducted for predicting the etiology of anaemia based on a developed algorithm (such as high-performance liquid chromatography [HPLC] and peripheral blood film analysis). Discussion: Being the largest study on anaemia during pregnancy in a single geographical area in Sri Lanka, this study will provide important clues about geographical clustering of anaemia cases with similar etiology, associated factors and etiologies which would help to develop interventions to improve the health of pregnant women in the area. The possibility of selection bias is a potential limitation associated with the study design.

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Iron deficiency among pregnant women attending an antenatal clinic in Northern Uganda: a cross-sectional study

10.21203/rs.2.14386/v1 ◽

2019 ◽

Author(s):

Samson Udho ◽

Joyce Nankumbi ◽

Mariam Namutebi ◽

Grace Ndeezi ◽

Joshua Epuitai ◽

...

Keyword(s):

Iron Deficiency ◽

Pregnant Women ◽

Serum Ferritin ◽

Antenatal Clinic ◽

Cross Sectional Study ◽

Sectional Study ◽

Third Trimester ◽

Cross Sectional ◽

Iron Supplements ◽

The Third

Abstract Background Iron deficiency is a leading cause of anemia among pregnant women in Uganda. However, due to the high cost of biochemical tests required to determine iron deficiency, the prevalence and factors associated with iron deficiency remain largely unstudied in our setting. Therefore, this study aimed at determining the prevalence of iron deficiency and its associated factors among pregnant women attending an antenatal clinic, Lira District-Uganda.Methods A cross-sectional study was conducted among 320 pregnant women attending an antenatal clinic at Lira Regional Referral Hospital. Maternal serum ferritin was used as a measure of iron deficiency and was determined using a Cobas 6000 Automated Analyzer. Iron deficiency was based on serum ferritin of <30 μg/L. A semi-structured questionnaire was used to obtain the characteristics of the study participants. Binary and multivariate logistic regression were performed to identify the associated factors.Results The prevalence of iron deficiency was 45%. Non-adherence to iron supplements (AOR: 2.05 95% CI: 1.02-4.12) & third trimester pregnancy (AOR: 1.88 95% CI: 1.20-2.94) were significantly associated with iron deficiency during pregnancy.Conclusion Nearly 5 in 10 of the participants had iron deficiency. Iron deficiency during pregnancy was associated with non-adherence to iron supplements and being in the third trimester of pregnancy. Midwives should encourage pregnant women to adhere to iron supplements during pregnancy especially pregnant women who are in the third trimester.

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Intimate partner violence against pregnant women: sociodemographic profile and characteristics of the aggressions

Revista Gaúcha de Enfermagem ◽

10.1590/1983-1447.2021.20200394 ◽

2021 ◽

Vol 42 ◽

Author(s):

Naiane Beatriz da Silva ◽

Rosely Erlach Goldman ◽

Hugo Fernandes

Keyword(s):

Black Women ◽

Pregnant Women ◽

Partner Violence ◽

Physical Violence ◽

First Trimester ◽

Cross Sectional Study ◽

Disease Notification ◽

Cross Sectional ◽

Notification System ◽

Sociodemographic Profile

ABSTRACT Objective: To identify the sociodemographic profile and the main characteristics of violence by intimate partners in pregnant women in São Paulo, Brazil. Method: Cross-sectional study based on notifications for suspected or confirmed cases of inter-police violence from the National Disease Notification System (SINAN) carried out in the 2016-2019 period. Collection was performed between March and June 2020. Chi-squared test or Fisher’s Exact test were used in statistical analysis. Results: A total of 4,269 notifications were obtained and the prevalent profile was women between 20 and 34 years old (62.5%), brown or black (51.3%), who have completed high school (22.5%) in the first trimester of pregnancy (44.2%). Physical violence was more frequent (48.3%), occurred at home (59.1%), motivated by sexism (22.29%). Sexual violence or rape was more frequent (85.4%) with abortion in cases provided for by law (39%). Conclusion: Adult brown or black women in the first gestational trimester experienced physical violence more frequently.

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Sociodemographic and Obstetric Characteristics of Anaemic Pregnant Women Attending Antenatal Clinic in Bolgatanga Regional Hospital

Scientifica ◽

10.1155/2016/4687342 ◽

2016 ◽

Vol 2016 ◽

pp. 1-8 ◽

Cited By ~ 3

Author(s):

Benjamin Ahenkorah ◽

Kwabena Nsiah ◽

Peter Baffoe

Keyword(s):

Pregnant Women ◽

Antenatal Clinic ◽

Cross Sectional Study ◽

Regional Hospital ◽

Antenatal Visit ◽

Third Trimester ◽

Cross Sectional ◽

Domestic Livestock ◽

Obstetric Factors ◽

Anaemia In Pregnancy

The study determined the sociodemographic and obstetric characteristics of pregnant women which contribute to the risk of developing anaemia. A cross-sectional study was conducted among 400 pregnant women attending their first antenatal visit at the Bolgatanga Regional Hospital Antenatal Clinic. Anaemia was significantly associated (p<0.05) with younger maternal age, parity, gravidity, trimester of pregnancy, and source of drinking water. Multivariate logistic regression identified the following factors with adjusted odds ratios (aOR) and 95% confidence intervals (CI): unemployment (aOR = 4.76 (CI: 2.26–11.33);p<0.0001), rural dwelling (aOR = 3.10 (CI: 2.16–4.91);p=0.0071), primigravida (aOR = 2.13 (CI: 1.34–3.18);p=0.0201), nulliparity (aOR = 1.92 (CI: 1.23–2.86);p=0.0231), first antenatal visit at second trimester (aOR = 1.71 (CI: 1.33–3.12);p=0.0149) and first antenatal visit at third trimester (aOR = 2.73 (CI: 1.24–4.35);p=0.0017), drinking from well and boreholes (aOR = 2.78 (CI: 2.27–5.21);p<0.0001), and the presence of domestic livestock (aOR = 2.15 (CI: 1.33–3.68);p=0.0019). This study has shown the various sociodemographic and obstetric factors which significantly contribute to anaemia in pregnancy.

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Sexual Function Alteration in First Trimester of Pregnancy Among *** Women

10.21203/rs.3.rs-436925/v2 ◽

2021 ◽

Author(s):

Hoang Dao Nhat Linh ◽

Le Sy Phuc An ◽

Le Minh Tam ◽

Nguyen Vu Quoc Huy

Keyword(s):

Sexual Function ◽

Pregnant Women ◽

First Trimester ◽

Cross Sectional Study ◽

Female Sexual Function Index ◽

Sexual Life ◽

Female Sexual Function ◽

Related Factors ◽

Cross Sectional ◽

Function Index

Abstract Introduction: A healthy sexual life would contribute to a lasting intimate couple relationship; pregnant women were susceptible to physical, psychological and social changes leading to sexual alterations and dysfunction in pregnancy. In ***, despite not being a novel domain, sexuality has not been extensively evaluated due to the influence of Eastern tradition, which creating promotes unsecured feelings of insecurity when talking about sex.Aim: To investigate the female sexual function alteration during the 1st trimester of pregnancy and some related factors among *** women.Methods: A descriptive cross-sectional study comprising 383 women aged from 18 years old having routine antenatal visits at Department of Obstetrics and Gynecology, *** Hospital from April 2016 to March 2017. Data were collected by interviews using is Female Sexual Function Index (FSFI) questionnaire.Main outcome measures: Subjects’ sexual function alteration, using the validated *** version of Female Sexual Function Index.Results: The prevalence of women with female sexual function alteration before pregnancy was 53% and in 1st trimester was 88.8%. The frequency of intercourses during 1st trimester of pregnancy is lower than before pregnancy (p<0.05). The main reasons of no sexual activity during pregnancy were fear of harming the fetus (75.1%) and prefer not to be satisfied in the short-term rather than hurt the baby (73.5%). Factors affected female sexual function were age, time of living-together, age of 1st sexual intercourse, pregnancy planning, obstetrical history, sexual initiative, religion, academic level, and jobs (p<0.05).Conclusions: Sexual function alteration among first trimester pregnant women is a problem which should be considered, and medical staff should provide counseling to them to improve the quality of their sexual life and maintain normal course of pregnancy.

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Seroprevalence rates of Toxoplasma gondii, Rubella, Cytomegalovirus among first trimester pregnant women in Istanbul

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20205749 ◽

2020 ◽

Vol 10 (1) ◽

pp. 22

Author(s):

Aysegul Ozer ◽

Mujde Canday ◽

Aslihan Yurtkal ◽

Ebru Alici Davutoglu ◽

Yasam Kemal Akpak ◽

...

Keyword(s):

Toxoplasma Gondii ◽

Pregnant Women ◽

First Trimester ◽

Cross Sectional Study ◽

University Hospital ◽

Infectious Agents ◽

Igg Antibody ◽

Cross Sectional ◽

Common Causes ◽

Obstetric Clinic

Background: Toxoplasma Gondii, Rubella, and Cytomegalovirus (CMV) are the most common causes of congenital infections worldwide. There is not a consensus on these infectious agents should be screened during pregnancy. The aim of this study is to determine the prevalence of toxoplasma, rubella, and CMV infections in order to know the need for antenatal screening.Methods: This retrospective cross-sectional study was performed on 1309 ambulatory pregnant patients who applied to the obstetric clinic of a university hospital between October 2016 and April 2018. Documents of patients in the first trimester were reviewed and serologic data of Toxoplasma gondii, CMV, Rubella infections were retrieved from the computer database.Results: Of 1309 pregnant women, positivity for anti-Toxoplasma IgG antibody was 352(26.9%), while 17(1.3%) of the subjects tested were positive for the anti-Toxoplasma IgM antibody. These positivities of the pregnant women for anti-Rubella IgG and IgM were 1147(87.6%) and (0.1%), respectively. These positivities of the pregnant women for anti-CMV IgG and IgM were 1163(88.8%) and 17(1.3%), respectively.Conclusions: We detected high rates of immunity against Rubella and CMV but low rates of immunity against Toxoplasma in this retrospective cohort of pregnant women. Due to high rates of seropositivity against Rubella and CMV, routine nationwide screening may not be necessary.

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