What Affects Quality of Life for People with Type 1 Diabetes?: A Cross-Sectional Observational Study

This study investigated the association between the quality of life (QOL) and type 1 diabetes mellitus (DM), a lifelong disease that requires constant management. A complex set of factors influence the QOL of people with type 1 DM, and understanding these factors requires further research. This research is a cross-sectional descriptive study. A survey on related variables such as acceptance of disease and efficacy for self-management of diabetes, was conducted among 111 participants with type 1 DM. The collected data were analyzed using PASW Statistics program, and factors influencing participants’ QOL were identified through hierarchical multiple regression. The study followed the Guidelines of Systematic Reporting of Examination in the STROBE checklist. The results showed that four variables exerted a significant effect on QOL (blood glucose level at hypoglycemia and complications in Model 1; efficacy for self-management of diabetes and acceptance and action in Model 2), and all the variables explained a majority of the variance in QOL. The results indicate that management of severe hypoglycemia and prevention of complications is crucial. Interventions should be developed to enhance coping abilities to improve efficacy for self-management for those with diabetes and promote their acceptance of the disease.

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Quality of Life in Romanian Children with Type 1 Diabetes: A Cross-Sectional Survey Using an Interdisciplinary Healthcare Intervention

Healthcare ◽

10.3390/healthcare8040382 ◽

2020 ◽

Vol 8 (4) ◽

pp. 382

Author(s):

Constanta Urzeală ◽

Aura Bota ◽

Silvia Teodorescu ◽

Mihaela Vlăiculescu ◽

Julien S Baker ◽

...

Keyword(s):

Quality Of Life ◽

Type 1 Diabetes ◽

Well Being ◽

Healthcare Intervention ◽

Type I ◽

Cross Sectional ◽

Significant Difference ◽

Interdisciplinary Healthcare

Background: The purpose of this study was to assess the quality of life in Romanian type 1 diabetes mellitus (T1DM) children attending an early interdisciplinary healthcare intervention. Hypothesis: engaging T1DM children in leisure sports leads to a better quality of life. Methods: This research embeds a cross-sectional observational study, incorporating some clinical characteristics relevant for diabetes management. The Kidscreen 27 questionnaire was issued to 100 T1DM children aged between 7 and 17 years. Parents completed the questionnaire. All subjects received interdisciplinary healthcare in the previous year. Statistics were performed using SPSS, v20. The required sample size of 100 subjects was obtained with a confidence interval of 95% and a sampling error of 0.009. The tests were two-sided, with a type I error set at 0.05. Results: Subjects reached an increased level of physical well-being, psychological well-being, autonomy, parent relationships, peer and social support, and school inclusion. There was a significant difference (p < 0.05) between children who practice leisure activities and children who only participated in physical education (PE) classes, regarding their physical well-being (t = 2.123). ANOVA demonstrated significant differences between age groups regarding physical well-being. Conclusion: The interdisciplinary healthcare intervention increased the efficiency of T1DM management with positive effects on life quality.

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Pathogenesis of Type 1 Diabetes Mellitus: A Brief Overview

Romanian Journal of Diabetes Nutrition and Metabolic Diseases ◽

10.2478/v10255-012-0009-1 ◽

2012 ◽

Vol 19 (1) ◽

pp. 67-72 ◽

Cited By ~ 1

Author(s):

Adrian Vlad ◽

Romulus Timar

Keyword(s):

Quality Of Life ◽

Diabetes Mellitus ◽

Type 1 Diabetes ◽

Insulin Therapy ◽

Type 1 Diabetes Mellitus ◽

Chronic Complications ◽

Type 1 Dm ◽

Preventive Methods

Pathogenesis of Type 1 Diabetes Mellitus: A Brief OverviewBefore the discovery of insulin, type 1 diabetes mellitus (DM) was a disease with acute evolution, leading to death shortly after diagnosis. During the first years of insulin therapy, the medical world was optimistic, even enthusiastic, considering that the therapeutic solution for the malady was found. Unfortunately this was only an illusion, because the patients started to develop chronic complications that shortened their lifespan and impaired their quality of life. In other words, insulin therapy transformed type 1 DM into a chronic disease. The prevention or the delay of the onset of hyperglycemia emerged as a new solution for the patients and, consequently, the understanding of the pathogenesis of the disease (a prerequisite for developing efficient preventive methods) became a priority for all the diabetologists involved in research. Almost 40 years have passed since the autoimmune theory regarding the pathogenesis of type 1 DM was imagined but, despite the tremendous research performed in this field since then, the prevention could not be obtained. The aim of this paper is to present the most important theoretic notions regarding the mechanisms that underlie the development of type 1 DM, in the way they are understood today.

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Relationship between Diabetes Family Conflicts or Problem Recognition in Illness Self-Management and Quality of Life of Adolescents with T1DM and Their Parents

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph182010710 ◽

2021 ◽

Vol 18 (20) ◽

pp. 10710

Author(s):

Mi-Kyoung Cho ◽

Mi Young Kim

Keyword(s):

Quality Of Life ◽

Type 1 Diabetes ◽

Peer Interactions ◽

Linear Regression Analysis ◽

Self Management ◽

Problem Recognition ◽

Family Conflicts ◽

Diabetes Family

This study aimed to investigate the relationship between diabetes family conflicts or problem recognition in illness self-management (PRISM) and the parental perceived quality of life (QoL) of adolescents with type 1 diabetes mellitus (T1DM) and their parents. This was a cross-sectional study, and the participants comprised 111 parents of type 1 diabetes adolescents; data were collected via an online survey and analyzed by descriptive statistics, correlation, and multiple linear regression analysis using the IBM SPSS 25.0 program. The explanatory power of the QoL model in parents of adolescents with T1DM, constructed using three variables—diabetes family conflict (B = −0.56), regimen pain and bother (B = −11.25), and peer interactions (B = −7.48), which are PRISM barriers—was 35.7% (F = 5.70, p < 0.001). Diabetes family conflicts (B = −0.86) and peer interactions (B = −9.04) explained 57.3% of the variance in the parental perceived QoL of adolescents with T1DM (F = 12.33, p < 0.001). In order to improve the QoL in parents and adolescents with type 1 diabetes, interventions to effectively manage diabetes family conflicts and improve peer interactions are necessary.

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Diabetes self-management, depressive symptoms, metabolic control and satisfaction with quality of life over time in Chinese youth with type 1 diabetes

Journal of Clinical Nursing ◽

10.1111/jocn.12698 ◽

2014 ◽

Vol 24 (9-10) ◽

pp. 1258-1268 ◽

Cited By ~ 13

Author(s):

Jia Guo ◽

Robin Whittemore ◽

Sangchoon Jeon ◽

Margaret Grey ◽

Zhi-Guang Zhou ◽

...

Keyword(s):

Quality Of Life ◽

Type 1 Diabetes ◽

Depressive Symptoms ◽

Metabolic Control ◽

Self Management ◽

Chinese Youth ◽

Over Time

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Health-Related Quality of Life, Family Conflicts and Fear of Injecting: Perception Differences between Preadolescents and Adolescents with Type 1 Diabetes and Their Mothers

Behavioral Sciences ◽

10.3390/bs11070098 ◽

2021 ◽

Vol 11 (7) ◽

pp. 98

Author(s):

Marta Tremolada ◽

Maria Cusinato ◽

Sabrina Bonichini ◽

Arianna Fabris ◽

Claudia Gabrielli ◽

...

Keyword(s):

Quality Of Life ◽

Diabetes Mellitus ◽

Type 1 Diabetes ◽

Self Regulation ◽

Type I ◽

Family Conflicts ◽

Cross Sectional ◽

Age Range

Good management of diabetes requires at the same time self-regulation behaviour and a balanced involvement of family components. This cross-sectional study’s aims were: understanding fear of injections and perceptions of family conflicts in preadolescents and adolescents with type 1 diabetes mellitus and their mothers, comparing their perceptions, and identifying the risk factors impacting patients’ quality of life. Eligibility criteria were: treatment for diabetes mellitus type I, currently aged 10–18 years, attending the hospital for annual hospital follow-ups. Exclusion criteria were: intellectual disabilities, inability to complete questionnaires alone and neuropsychiatric illness with active pharmacotherapy. The study design was cross-sectional. Participants were one hundred and two patients (Mean age = 14.6, SD = 2.4; age range = 10–19 years; Females = 52 and Males = 50) and their mothers (Mean age = 46.9, SD = 6.2, age range = 27–63 years), who filled in self and proxy-report questionnaires (N total= 204). The results showed that 20% of patients and 14.7% of their mothers reported clinical scores for fear of self-injection and blood testing. The mothers reported lower fear of injecting and higher family conflicts compared with the patients. Age, fear of injecting and family conflicts were significantly associated with patients’ quality of life perceptions. Clinical considerations and recommendations are given based on the empirical results.

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Improved Health-Related Quality of Life in a Phase 3 Islet Transplantation Trial in Type 1 Diabetes Complicated by Severe Hypoglycemia

Diabetes Care ◽

10.2337/dc17-1779 ◽

2018 ◽

Vol 41 (5) ◽

pp. 1001-1008 ◽

Cited By ~ 42

Author(s):

Eric D. Foster ◽

Nancy D. Bridges ◽

Irene D. Feurer ◽

Thomas L. Eggerman ◽

Lawrence G. Hunsicker ◽

...

Keyword(s):

Quality Of Life ◽

Type 1 Diabetes ◽

Islet Transplantation ◽

Severe Hypoglycemia ◽

Health Related Quality ◽

Phase 3 ◽

Related Quality ◽

Health Related

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The Effects of Diabetes Self-Management Education on Quality of Life for Persons With Type 1 Diabetes: A Systematic Review of Randomized Controlled Trials

The Science of Diabetes Self-Management and Care ◽

10.1177/26350106211070266 ◽

2022 ◽

pp. 263501062110702

Author(s):

Patricia Davidson ◽

Jacqueline LaManna ◽

Jean Davis ◽

Maria M. Ojeda ◽

Suzanne Hyer ◽

...

Keyword(s):

Quality Of Life ◽

Systematic Review ◽

Type 1 Diabetes ◽

Management Education ◽

Self Management ◽

Secondary Outcome ◽

Controlled Trials ◽

Randomized Controlled

Purpose: It is well documented that chronic conditions, such as diabetes, impact quality of life (QoL). QoL assessment is essential when developing and evaluating diabetes self-management education support interventions. The aim of this systematic review was to evaluate the evidence and gaps in the research and the impact of diabetes self-management education (DSME) on QoL outcomes in persons with type 1 diabetes mellitus (T1DM). Methods A systematic review of English language studies published between January 1, 2007, and March 31, 2020, was conducted using a modified Cochrane review method. Studies were included if they were randomized controlled trials (RCTs), participants had T1DM with or without caregivers, a DSME intervention alone or a component(s) of the ADCES7™ Self-Care Behaviors was described, and QoL was a primary or secondary outcome. A 3-tiered review process was utilized for selecting articles. Retained articles were assessed for risk of bias. Results: Nineteen articles, reporting on 17 RCTs, met inclusion criteria, of which 7 studies reported QoL as the primary outcome and 10 as a secondary outcome. Seven studies detected significant impact of DMSE on QoL outcomes in either the participants or family caregivers, which varied in participant populations, selection of QoL tools (generic vs diabetes-specific), intervention type, intervention length, and type of interventionist. Conclusion: DSME has the potential to influence QoL outcomes in people with T1DM. Research using more standardized methods are needed to delineate impact on a broader range of factors that influence QoL for those living with T1DM across the life span and their caregivers.

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Measuring the Quality of Life Among Children with Type 1 Diabetes in NGHA Riyadh

Current Developments in Nutrition ◽

10.1093/cdn/nzaa059_003 ◽

2020 ◽

Vol 4 (Supplement_2) ◽

pp. 1286-1286

Author(s):

Nouf Altheyabi

Keyword(s):

Quality Of Life ◽

Type 1 Diabetes ◽

Well Being ◽

Cross Sectional Study ◽

Average Score ◽

Pediatric Endocrinology ◽

Cross Sectional ◽

Scale Scores

Abstract Objectives Aim of the Study: (Instructions: state the goal you need to achieve) Evaluate the quality of life in children with type 1 diabetes. Specific Objectives: (Instructions: state the details of each objective that will finally lead to achievement of the goal) 1. To assess the quality of life in children and adolescents with type 1 diabetes using the HR-QOL questionnaire. 2. To determine the characteristics associated with quality of life in children with type 1 diabetes. Methods A descriptive cross-sectional study done in Pediatric Endocrinology clinic at the King Abdullah Specialist Children Hospital (KASCH). Quality of life was evaluated during a personal interview with each patient using the diabetes- specific quality of life (QOL) tool KINDL-R Diabetes Module (DM). The questionnaire consists of 41 items related to quality of life and diabetes. Demographics, anthropometric measurements, and HbA1c were reviewed from patient records. Results Overall quality of life was good with average score of (67.9%). There was no statistical difference between males and females in sub scale scores such as physical and emotional well-being. Also, there was no significant correlation between HbA1c, BMI and sub scale scores. Conclusions Poor glycemic control, BMI, and sex were not associated with worse QoL. Further studies to determine the optimal cut points for QoL scales are needed to identify T1D patients with poor QoL. Funding Sources in NGHA Riyadh.

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