scholarly journals The Role of Short-Chain Fatty Acids in the Interplay between a Very Low-Calorie Ketogenic Diet and the Infant Gut Microbiota and Its Therapeutic Implications for Reducing Asthma

2020 ◽  
Vol 21 (24) ◽  
pp. 9580
Author(s):  
Naser A. Alsharairi
Keyword(s):  
Fatty Acids ◽  
Gut Microbiota ◽  
Ketogenic Diet ◽  
Potential Role ◽  
Short Chain Fatty Acids ◽  
Short Chain ◽  
Low Calorie ◽  
Pregnancy And Lactation ◽  
Chain Fatty Acids

Gut microbiota is well known as playing a critical role in inflammation and asthma development. The very low-calorie ketogenic diet (VLCKD) is suggested to affect gut microbiota; however, the effects of VLCKD during pregnancy and lactation on the infant gut microbiota are unclear. The VLCKD appears to be more effective than caloric/energy restriction diets for the treatment of several diseases, such as obesity and diabetes. However, whether adherence to VLCKD affects the infant gut microbiota and the protective effects thereof on asthma remains uncertain. The exact mechanisms underlying this process, and in particular the potential role of short chain fatty acids (SCFAs), are still to be unravelled. Thus, the aim of this review is to identify the potential role of SCFAs that underlie the effects of VLCKD during pregnancy and lactation on the infant gut microbiota, and explore whether it incurs significant implications for reducing asthma.

scholarly journals The Role of Short-Chain Fatty Acids in Mediating Very Low-Calorie Ketogenic Diet-Infant Gut Microbiota Relationships and Its Therapeutic Potential in Obesity

Nutrients ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 3702
Author(s):  
Naser A. Alsharairi
Keyword(s):  
Gut Microbiota ◽  
Ketogenic Diet ◽  
Therapeutic Potential ◽  
Short Chain Fatty Acids ◽  
Short Chain ◽  
Protective Effects ◽  
Low Calorie ◽  
Pregnancy And Lactation ◽  
Gut Microbiota Composition

As the very low-calorie ketogenic diet (VLCKD) gains increased interest as a therapeutic approach for many diseases, little is known about its therapeutic use in childhood obesity. Indeed, the role of VLCKD during pregnancy and lactation in influencing short chain fatty acid (SCFA)-producing bacteria and the potential mechanisms involved in the protective effects on obesity are still unclear. Infants are characterized by a diverse gut microbiota composition with higher abundance of SCFA-producing bacteria. Maternal VLCKD during pregnancy and lactation stimulates the growth of diverse species of SCFA-producing bacteria, which may induce epigenetic changes in infant obese gene expression and modulate adipose tissue inflammation in obesity. Therefore, this review aims to determine the mechanistic role of SCFAs in mediating VLCKD-infant gut microbiota relationships and its protective effects on obesity.

scholarly journals Role of Gut Microbiota-Generated Short-Chain Fatty Acids in Metabolic and Cardiovascular Health

2018 ◽  
Vol 7 (4) ◽  
pp. 198-206 ◽  
Author(s):  
Edward S. Chambers ◽  
Tom Preston ◽  
Gary Frost ◽  
Douglas J. Morrison
Keyword(s):  
Fatty Acids ◽  
Gut Microbiota ◽  
Cardiovascular Health ◽  
Short Chain Fatty Acids ◽  
Short Chain ◽  
Chain Fatty Acids

scholarly journals The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism

2013 ◽  
Vol 54 (9) ◽  
pp. 2325-2340 ◽  
Author(s):  
Gijs den Besten ◽  
Karen van Eunen ◽  
Albert K. Groen ◽  
Koen Venema ◽  
Dirk-Jan Reijngoud ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Energy Metabolism ◽  
Gut Microbiota ◽  
Short Chain Fatty Acids ◽  
Short Chain ◽  
Chain Fatty Acids

The interplay among gut microbiota, hypertension and kidney diseases: The role of short-chain fatty acids

2019 ◽  
Vol 141 ◽  
pp. 366-377 ◽  
Author(s):  
R.J.F. Felizardo ◽  
I. K.M. Watanabe ◽  
Patrizia Dardi ◽  
L.V. Rossoni ◽  
N.O.S. Câmara
Keyword(s):  
Fatty Acids ◽  
Gut Microbiota ◽  
Kidney Diseases ◽  
Short Chain Fatty Acids ◽  
Short Chain ◽  
Chain Fatty Acids

The Consumption of Galactomannan Effervescent Drinks made from Coconut Pulp Waste and Colonic Microbiota in Wistar Rats

2020 ◽  
Vol 15 (1) ◽  
pp. 52-56
Author(s):  
Sri Winarti ◽  
Agung Pasetyo
Keyword(s):  
Fatty Acids ◽  
Gut Microbiota ◽  
Wistar Rats ◽  
Short Chain Fatty Acids ◽  
Short Chain ◽  
E Coli ◽  
Colonic Microbiota ◽  
Male Wistar Rats ◽  
Lactobacillus Spp ◽  
Chain Fatty Acids

The consumption of prebiotics is known to affect the balance of gut microbiota. The purpose of this study was to explore how a galactomannan-rich effervescent drink can affect the population of Lactobacillus, Bifidobacterium, E. coli, and the concentration of short-chain fatty acids in the cecum of rats. Twenty-eight male Wistar rats (aged 2 months) were divided equally into 7 groups and treated orally each day for 15 days with 2 mL effervescent drinks with increasing levels of prebiotic galactomannan. The dosage of 500 mg galactomannan increased the growth of Lactobacillus spp. and Bifidobacterium spp. with inhibition of the growth of E.coli with increased formation of short-chain fatty acids such as acetate, propionate, and butyrate in the cecum of rats.

Impact of oral COMT-inhibitors on gut microbiota and short chain fatty acids in Parkinson's disease

2020 ◽  
Vol 70 ◽  
pp. 20-22 ◽  
Author(s):  
Daniel Grün ◽  
Valerie C. Zimmer ◽  
Jil Kauffmann ◽  
Jörg Spiegel ◽  
Ulrich Dillmann ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Fatty Acids ◽  
Parkinson's Disease ◽  
Gut Microbiota ◽  
Short Chain Fatty Acids ◽  
Short Chain ◽  
Comt Inhibitors ◽  
Chain Fatty Acids
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