scholarly journals High Power Electromagnetic Waves Exposure of Healthy and Tumor Bearing Mice: Assessment of Effects on Mice Growth, Behavior, Tumor Growth, and Vessel Permeabilization

2021 ◽  
Vol 22 (16) ◽  
pp. 8516
Author(s):  
Jelena Kolosnjaj-Tabi ◽  
Muriel Golzio ◽  
Elisabeth Bellard ◽  
Alexandre Catrain ◽  
Thomas Chretiennot ◽  
...  
Keyword(s):  
Pilot Study ◽  
Electric Fields ◽  
High Power ◽  
Electromagnetic Waves ◽  
Field Experiments ◽  
Narrow Band ◽  
Biological Effects ◽  
Wide Band ◽  
Tumor Bearing ◽  
Peak Value

High power radiofrequencies may transiently or permanently disrupt the functioning of electronic devices, but their effect on living systems remains unknown. With the aim to evaluate the safety and biological effects of narrow-band and wide-band high-power electromagnetic (HPEM) waves, we studied their effects upon exposure of healthy and tumor-bearing mice. In field experiments, the exposure to 1.5 GHz narrow-band electromagnetic fields with the incident amplitude peak value level in the range of 40 kV/m and 150 MHz wide-band electric fields with the amplitude peak value in the range of 200 kV/m, did not alter healthy and tumor-bearing animals’ growth, nor it had any impact on cutaneous murine tumors’ growth. While we did not observe any noticeable behavioral changes in mice during the exposure to narrow-band signals when wide-band HPEM signals were applied, mice could behave in a similar way as they respond to loud noise signals: namely, if a mouse was exploring the cage prior to signal application, it returned to companion mates when wide-band HPEM signals were applied. Moreover, the effect of wide-band signals was assessed on normal blood vessels permeability in real-time in dorsal-chamber-bearing mice exposed in a pilot study using wide-band signal applicators. Our pilot study conducted within the applicator and performed at the laboratory scale suggests that the exposure to wide-band signals with the amplitude of 47.5 kV/m does not result in increased vessel permeability.

scholarly journals Evaluations of Acute and Sub-Acute Biological Effects of Narrowband and Moderate-Band High Power Electromagnetic Waves on Cellular Spheroids

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Laure Gibot ◽  
Jelena Kolosnjaj-Tabi ◽  
Elisabeth Bellard ◽  
Thomas Chretiennot ◽  
Quentin Saurin ◽  
...  
Keyword(s):  
Electric Fields ◽  
High Power ◽  
Electromagnetic Waves ◽  
Biological Effects ◽  
Membrane Integrity ◽  
Dermal Fibroblasts ◽  
Mitochondrial Potential ◽  
Cellular Spheroids ◽  
Physiological Processes ◽  
Electromagnetic Signals

Abstract High power electromagnetic signals can disrupt the functioning of electronic devices. As electromagnetism plays a role in cells homeostasis, such electromagnetic signals could potentially also alter some physiological processes. Herein we report on distinct biological parameters assessment after cellular spheroids exposure to high power electromagnetic signals, such as the ones used for defense applications. Signals effects were assessed in tumor cells spheroids and in normal human dermal fibroblasts spheroids, where macroscopic aspect, growth, plasma membrane integrity, induction of apoptosis, ATP content, and mitochondrial potential were investigated after spheroids exposure to high power electromagnetic signals. No significant effects were observed, indicating that 1.5 GHz narrowband electromagnetic fields with incident amplitude level of 40 kV/m, and 150 MHz moderate-band electric fields with an amplitude of 72.5 to approximately 200 kV/m, do not cause any significant alterations of assessed parameters.

Biological effects of narrow band pulsed electric fields

2007 ◽  
Vol 14 (3) ◽  
pp. 663-668 ◽  
Author(s):  
Sunao Katsuki ◽  
Naoyuki Nomura ◽  
Hideto Koga ◽  
Hidenori Akiyama ◽  
Ichiro Uchida ◽  
...  
Keyword(s):  
Electric Fields ◽  
Narrow Band ◽  
Biological Effects ◽  
Pulsed Electric Fields

HIGH-POWER NARROW-BAND TUNEABLE IMPACT PERIODIC DYE LASER

2010 ◽  
Vol 69 (14) ◽  
pp. 1301-1309
Author(s):  
V. P. Pelipenko ◽  
P.G. Dalchenko ◽  
M. I. Dzyubenko
Keyword(s):  
High Power ◽  
Narrow Band ◽  
Dye Laser

scholarly journals Blinding in electric current stimulation in subacute neglect patients with current densities of 0.8 A/m2: a cross-over pilot study

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Anna Gorsler ◽  
Ulrike Grittner ◽  
Nadine Külzow ◽  
Torsten Rackoll
Keyword(s):  
Pilot Study ◽  
Electric Fields ◽  
Standard Care ◽  
Small Sample Size ◽  
Small Sample ◽  
Related Factors ◽  
Attentional Deficits ◽  
Age Related ◽  
Current Densities ◽  
Improve Standard

Abstract Objective Neglect after stroke is a disabling disorder and its rehabilitation is a major challenge. Transcranial direct current stimulation (tDCS) seems to be a promising adjuvant technique to improve standard care neglect therapy. Since electric fields are influenced by age-related factors, higher current densities are probably needed for effective treatment in aged stroke patients. Validation of treatment efficacy requires sham-controlled experiments, but increased current densities might comprise blinding. Therefore, a pilot study was conducted to test sham adequacy when using current density of 0.8 A/m2. Whether especially neglect patients who mainly suffer from perceptual and attentional deficits are able to differentiate beyond chance active from sham tDCS was investigated in a randomized cross-over design (active/sham stimulation) in 12 early subacute patients with left-sided hemineglect. Stimulation (0.8 A/m2) was performed simultaneous to standard care neglect therapy. Results Odds ratio of correct guessing an atDCS condition compared to wrongly judge an atDCS condition as sham was 10.00 (95%CI 0.65–154.40, p = 0.099). However, given the small sample size and high OR, although likely somewhat overestimated, results require careful interpretation and blinding success in neglect studies with current densities of 0.8 A/m2 should be further confirmed.

MUTUAL NONLINEAR INTERACTION OF A NUMBER OF ELECTROMAGNETIC WAVES IN A PLASMA

1963 ◽  
Vol 41 (10) ◽  
pp. 1702-1711 ◽  
Author(s):  
Mahendra Singh Sodha ◽  
Carl J. Palumbo
Keyword(s):  
Wave Equation ◽  
Electric Fields ◽  
Current Density ◽  
Nonlinear Interaction ◽  
Electromagnetic Waves ◽  
Physical Significance ◽  
Mutual Interaction ◽  
Modulated Waves ◽  
Boltzmann's Equation ◽  
Uniform Plasma

In this communication the authors have obtained an expression for current density in a slightly ionized uniform plasma in the presence of a number of electric fields of different frequencies by solving the appropriate Boltzmann's equation. This expression along with the wave equation has been used to investigate the nonlinear mutual interaction of a number of electromagnetic waves, propagating in a plasma. Limitations of the present analysis have also been indicated and the physical significance of the results has been discussed. The technique has also been applied to investigate the mutual interaction of amplitude-modulated waves, and the results express a generalization of Luxembourg effect to a number of strong modulated waves.

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