scholarly journals Synthesis and Application of Silica-Coated Quantum Dots in Biomedicine

2021 ◽  
Vol 22 (18) ◽  
pp. 10116
Author(s):  
Xuan-Hung Pham ◽  
Seung-Min Park ◽  
Kyeong-Min Ham ◽  
San Kyeong ◽  
Byung Sung Son ◽  
...  

Quantum dots (QDs) are semiconductor nanoparticles with outstanding optoelectronic properties. More specifically, QDs are highly bright and exhibit wide absorption spectra, narrow light bands, and excellent photovoltaic stability, which make them useful in bioscience and medicine, particularly for sensing, optical imaging, cell separation, and diagnosis. In general, QDs are stabilized using a hydrophobic ligand during synthesis, and thus their hydrophobic surfaces must undergo hydrophilic modification if the QDs are to be used in bioapplications. Silica-coating is one of the most effective methods for overcoming the disadvantages of QDs, owing to silica’s physicochemical stability, nontoxicity, and excellent bioavailability. This review highlights recent progress in the design, preparation, and application of silica-coated QDs and presents an overview of the major challenges and prospects of their application.

2014 ◽  
Vol 124 ◽  
pp. 132-139 ◽  
Author(s):  
Xiaoyuan Ji ◽  
Fei Peng ◽  
Yiling Zhong ◽  
Yuanyuan Su ◽  
Yao He

2021 ◽  
Vol 8 ◽  
Author(s):  
Muhammad Imran ◽  
Muhammad Jawwad Saif ◽  
Tahir Farooq ◽  
Javed Iqbal

Thiols are efficient capping agents used for the synthesis of semiconductor and metal nanoparticles. Commonly, long-chain thiols are used as passivating agents to provide stabilization to nanoparticles. Theoretical methods rarely reported aromatic thiol ligands’ effects on small-sized CdTe quantum dots’ structural and electronic properties. We have studied and compared the structural and electronic properties of (i) bare and (ii) aromatic thiols (thiophenol, 4-methoxybenzenethiol, 4-mercaptobenzonitrile, and 4-mercaptobenzoic acid) capped CdnTen quantum dots (QDs). Aromatic thiols are used as thiol-radical because of the higher tendency of thiol-radicals to bind with Cd atoms. This work provides an understanding of how the capping agents affect specific properties. The results show that all aromatic thiol-radical ligands caused significant structural distortion in the geometries. The aromatic thiol-radical ligands stabilize LUMOs, stabilize or destabilize HOMOs, and decrease HOMO-LUMO gaps for all the capped QDs. The stabilization of LUMOs is more pronounced than the destabilization of HOMOs. We also studied the effect of solvent on structural and electronic properties. TD-DFT calculations were performed to calculate the absorption spectra of bare and capped QDs, and all the capping ligands resulted in the redshift of absorption spectra.


2018 ◽  
Vol 106 ◽  
pp. 113-123 ◽  
Author(s):  
Jing Xue ◽  
Jixian Liu ◽  
Sui Mao ◽  
Yao Wang ◽  
Wenfei Shen ◽  
...  

Quantum dots (QDs) have shown promising potential to many biomedical and biological applications, mainly in drug delivery or activation and cellular imaging. These semiconductor nanoparticles, QDs, whose particle size is in the range of 2-10 nanometer with unique photo-chemical and -physical properties that are not possessed by any other isolated molecules, have become one of the distinct class of imaging probes and worldwide platforms for manufacturing of multifunctional nanodevices. In this chapter, properties, applications of QDs, and importance in the biomedical field especially in drug delivery is presented.


2019 ◽  
Vol 7 (24) ◽  
pp. 7279-7287 ◽  
Author(s):  
Tong Yan ◽  
Yunyan Li ◽  
Xiaoxiao Song ◽  
Jie Wang ◽  
Zhuoying Xie ◽  
...  

The cytotoxicities of the elements of current quantum dots (QDs) greatly restrict their applications in biomedical fields.


2019 ◽  
Vol 7 (46) ◽  
pp. 14441-14453 ◽  
Author(s):  
Aobo Ren ◽  
Liming Yuan ◽  
Hao Xu ◽  
Jiang Wu ◽  
Zhiming Wang

Heterogeneous integration of III–V quantum dots on Si substrates for infrared photodetection is reviewed, focusing on direct epitaxial growth and bonding techniques over the last few years.


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